{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T16:44:40Z","timestamp":1782924280615,"version":"3.54.5"},"reference-count":17,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmacological and Toxicological Methods"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1016\/j.vascn.2010.05.014","type":"journal-article","created":{"date-parts":[[2010,6,5]],"date-time":"2010-06-05T04:31:16Z","timestamp":1275712276000},"page":"6-11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Combined cardiopulmonary assessments with implantable telemetry device in conscious freely moving cynomolgus monkeys"],"prefix":"10.1016","volume":"62","author":[{"given":"S.","family":"Authier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Haefner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Fournier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Troncy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.B.","family":"Moon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vascn.2010.05.014_bib1","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1254\/jphs.QT-A4","article-title":"QT PRODACT: In vivo QT assay with a conscious monkey for assessment of the potential for drug-induced QT interval prolongation","volume":"99","author":"Ando","year":"2005","journal-title":"Journal of Pharmacological Sciences"},{"key":"10.1016\/j.vascn.2010.05.014_bib2","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.yrtph.2009.07.010","article-title":"Respiratory safety pharmacology: Positive control drug responses in Sprague\u2013Dawley rats, Beagle dogs and cynomolgus monkeys","volume":"55","author":"Authier","year":"2009","journal-title":"Regulatory Toxicology & Pharmacology"},{"key":"10.1016\/j.vascn.2010.05.014_bib3","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.vascn.2007.03.010","article-title":"A cardiovascular monitoring system in conscious cynomolgus monkeys for regulatory safety pharmacology. Part 1: Non-pharmacological validation","volume":"56","author":"Authier","year":"2007","journal-title":"Journal of Pharmacological & Toxicological Methods"},{"key":"10.1016\/j.vascn.2010.05.014_bib4","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.vascn.2007.03.011","article-title":"A cardiovascular monitoring system used in conscious cynomolgus monkeys for regulatory safety pharmacology. Part 2: Pharmacological validation","volume":"56","author":"Authier","year":"2007","journal-title":"Journal of Pharmacological & Toxicological Methods"},{"key":"10.1016\/j.vascn.2010.05.014_bib5","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.vascn.2009.05.003","article-title":"Measuring the risk of torsades de pointes: Electrocardiographic evaluation of PNU-142093 in conscious cynomolgus non-human primates using restraint and non-restraint procedures","volume":"60","author":"Bass","year":"2009","journal-title":"Journal of Pharmacological & Toxicological Methods"},{"key":"10.1016\/j.vascn.2010.05.014_bib6","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1046\/j.1460-9592.2001.00989.x","article-title":"Correlation of impedance minute ventilation with measured minute ventilation in a rate responsive pacemaker","volume":"24","author":"Cole","year":"2001","journal-title":"Pacing & Clinical Electrophysiology"},{"key":"10.1016\/j.vascn.2010.05.014_bib7","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1111\/j.1540-8159.2000.tb07015.x","article-title":"Influence of posture, breathing pattern, and type of exercise on minute ventilation estimation by a pacemaker transthoracic impedance sensor","volume":"23","author":"Duru","year":"2000","journal-title":"Pacing & Clinical Electrophysiology"},{"key":"10.1016\/j.vascn.2010.05.014_bib8","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1111\/j.1540-8159.1989.tb01838.x","article-title":"Behavior of a respiratory driven pacemaker and direct respiratory measurements","volume":"12","author":"Jordaens","year":"1989","journal-title":"Pacing & Clinical Electrophysiology"},{"key":"10.1016\/j.vascn.2010.05.014_bib9","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.vascn.2008.07.001","article-title":"Benchmarking safety pharmacology regulatory packages and best practice","volume":"58","author":"Lindgren","year":"2008","journal-title":"Journal of Pharmacological & Toxicological Methods"},{"key":"10.1016\/j.vascn.2010.05.014_bib10","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1038\/bjp.2008.206","article-title":"Dose\u2013response effects of sotalol on cardiovascular function in conscious, freely moving Cynomolgus monkeys","volume":"154","author":"Lynch","year":"2008","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.vascn.2010.05.014_bib11","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1111\/j.1540-8159.1988.tb06322.x","article-title":"Rate responsive pacing using a minute ventilation sensor","volume":"11","author":"Mond","year":"1988","journal-title":"Pacing & Clinical Electrophysiology"},{"key":"10.1016\/j.vascn.2010.05.014_bib12","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1038\/bjp.2008.280","article-title":"Principles of safety pharmacology","volume":"154","author":"Pugsley","year":"2008","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.vascn.2010.05.014_bib13","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/pst.338","article-title":"Impact of baseline ECG collection on the planning, analysis and interpretation of \u2018thorough\u2019 QT trials","volume":"8","author":"Sethuraman","year":"2009","journal-title":"Pharmaceutical Statistics"},{"key":"10.1016\/j.vascn.2010.05.014_bib14","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/nbt0410-307","article-title":"Fresh from the biologic pipeline\u20142009","volume":"28","author":"Sheridan","year":"2010","journal-title":"Nature Biotechnology"},{"key":"10.1016\/j.vascn.2010.05.014_bib15","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1046\/j.1460-9592.2003.00331.x","article-title":"Comparison of impedance minute ventilation and direct measured minute ventilation in a rate adaptive pacemaker","volume":"26","author":"Simon","year":"2003","journal-title":"Pacing & Clinical Electrophysiology"},{"key":"10.1016\/j.vascn.2010.05.014_bib16","author":"U.S. FOOD AND DRUG ADMINISTRATION"},{"key":"10.1016\/j.vascn.2010.05.014_bib17","author":"U.S. FOOD AND DRUG ADMINISTRATION"}],"container-title":["Journal of Pharmacological and Toxicological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056871910000870?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056871910000870?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T23:54:24Z","timestamp":1761004464000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1056871910000870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["S1056871910000870"],"URL":"https:\/\/doi.org\/10.1016\/j.vascn.2010.05.014","relation":{},"ISSN":["1056-8719"],"issn-type":[{"value":"1056-8719","type":"print"}],"subject":[],"published":{"date-parts":[[2010,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Combined cardiopulmonary assessments with implantable telemetry device in conscious freely moving cynomolgus monkeys","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmacological and Toxicological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vascn.2010.05.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}