{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:50:16Z","timestamp":1790675416991,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmacological and Toxicological Methods"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.vascn.2012.04.006","type":"journal-article","created":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T23:54:22Z","timestamp":1335830062000},"page":"8-13","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"title":["Comparison of manual and automated filaments for evaluation of neuropathic pain behavior in rats"],"prefix":"10.1016","volume":"66","author":[{"given":"Ramakrishna","family":"Nirogi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkatesh","family":"Goura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhanalakshmi","family":"Shanmuganathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep","family":"Jayarajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renny","family":"Abraham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vascn.2012.04.006_bb0005","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.pain.2009.11.015","article-title":"Acetazolamide and midazolam act synergistically to inhibit neuropathic pain","volume":"148","author":"Asiedu","year":"2010","journal-title":"Pain"},{"key":"10.1016\/j.vascn.2012.04.006_bb0010","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0304-3959(90)90022-6","article-title":"Further evidence for \u2018pain-related\u2019 behaviours in a model of unilateral peripheral mononeuropathy","volume":"41","author":"Attal","year":"1990","journal-title":"Pain"},{"key":"10.1016\/j.vascn.2012.04.006_bb0015","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0363-5023(87)80189-2","article-title":"The repeatability of testing with Semmes\u2013Weinstein monofilaments","volume":"12","author":"Bell-Krotoski","year":"1987","journal-title":"Journal of Hand Surgery"},{"key":"10.1016\/j.vascn.2012.04.006_bb0020","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0304-3959(88)90209-6","article-title":"A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man","volume":"33","author":"Bennett","year":"1988","journal-title":"Pain"},{"key":"10.1016\/j.vascn.2012.04.006_bb0025","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/bja\/87.1.12","article-title":"Mechanisms of neuropathic pain","volume":"87","author":"Bridges","year":"2001","journal-title":"British Journal of Anaesthesiology"},{"key":"10.1016\/j.vascn.2012.04.006_bb0030","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-0270(94)90144-9","article-title":"Quantitative assessment of allodynia in the rat paw","volume":"53","author":"Chaplan","year":"1994","journal-title":"Journal of Neuroscience Methods"},{"key":"10.1016\/j.vascn.2012.04.006_bb0035","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1146\/annurev.pa.20.040180.002301","article-title":"Efficient analysis of experimental observations","volume":"20","author":"Dixon","year":"1980","journal-title":"Annual Review of Pharmacology and Toxicololgy"},{"key":"10.1016\/j.vascn.2012.04.006_bb0040","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1385\/0-89603-129-2:145","article-title":"Techniques for assessing the effects of drugs on nociceptive responses","volume":"13","author":"Franklin","year":"1990","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.vascn.2012.04.006_bb0045","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1016\/j.bcp.2007.08.010","article-title":"A-366833: a novel nicotinonitrile-substituted 3,6-diazabicyclo [3.2.0]-heptane \u03b14\u03b22 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models","volume":"74","author":"Ji","year":"2007","journal-title":"Biochemical Pharmacology"},{"key":"10.1016\/j.vascn.2012.04.006_bb0050","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1017\/S0265021507000221","article-title":"Assessment of the clinical relevance of quantitative sensory testing with Von Frey monofilaments in patients with allodynia and neuropathic pain. A pilot study","volume":"24","author":"Keizer","year":"2007","journal-title":"European Journal of Anaesthesiology"},{"key":"10.1016\/j.vascn.2012.04.006_bb0055","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0304-3959(92)90041-9","article-title":"An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat","volume":"50","author":"Kim","year":"1992","journal-title":"Pain"},{"key":"10.1016\/j.vascn.2012.04.006_bb0060","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1080\/00207450802174506","article-title":"Regional differences in epidermal thickness and behavioral response following partial denervation of the rat paw","volume":"118","author":"Kojundzic","year":"2008","journal-title":"International Journal of Neuroscience"},{"issue":"10","key":"10.1016\/j.vascn.2012.04.006_bb0065","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.jpain.2009.06.002","article-title":"Translational pain research: Achievements and challenges","volume":"10","author":"Mao","year":"2009","journal-title":"Pain"},{"key":"10.1016\/j.vascn.2012.04.006_bb0070","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0165-0270(98)00083-1","article-title":"Assessing mechanical allodynia in the rat paw with a new electronic algometer","volume":"84","author":"Moller","year":"1998","journal-title":"Journal of Neuroscience Methods"},{"key":"10.1016\/j.vascn.2012.04.006_bb0075","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1007\/s12630-010-9318-0","article-title":"Attenuation of neuropathy-induced allodynia intraplantar injection of Pregabalin","volume":"57","author":"Park","year":"2010","journal-title":"Journal of Canadian Anesthesiolgy"},{"key":"10.1016\/j.vascn.2012.04.006_bb0080","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.brainres.2009.07.091","article-title":"Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models","volume":"1295","author":"Piesla","year":"2009","journal-title":"Brain Research"},{"key":"10.1016\/j.vascn.2012.04.006_bb0085","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.ejpain.2009.08.010","article-title":"Modality of hyperalgesia tested, not type of nerve damage, predicts pharmacological sensitivity in rat models of neuropathic pain","volume":"14","author":"Pradhan","year":"2010","journal-title":"European Journal of Pain"},{"key":"10.1016\/j.vascn.2012.04.006_bb0090","doi-asserted-by":"crossref","first-page":"5l","DOI":"10.1016\/0006-8993(95)01452-7","article-title":"Systemic ketamine attenuates nociceptive behaviors in a rat model of peripheral neuropathy","volume":"715","author":"Qian","year":"1996","journal-title":"Brain Research"},{"key":"10.1016\/j.vascn.2012.04.006_bb0095","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0304-3959(90)91074-S","article-title":"A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury","volume":"43","author":"Seltzer","year":"1990","journal-title":"Pain"},{"key":"10.1016\/j.vascn.2012.04.006_bb0100","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.pain.2007.12.008","article-title":"Clinical and preclinical assessment: Are we measuring the same thing?","volume":"135","author":"Vierck","year":"2008","journal-title":"Pain"},{"key":"10.1016\/j.vascn.2012.04.006_bb0105","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1213\/01.ANE.0000158471.41575.F0","article-title":"A behavioral and pharmacological validation of the acetone spray test in gerbils with a chronic constriction Injury","volume":"101","author":"Vissers","year":"2005","journal-title":"Anesthesiology and Analgesia"},{"key":"10.1016\/j.vascn.2012.04.006_bb0110","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/s0304-3959(02)00382-2","article-title":"\u2018CatWalk\u2019 automated quantitative gait analysis as a novel method to assess mechanical allodynia in the rat; a comparison with Von Frey testing","volume":"102","author":"Vrinten","year":"2003","journal-title":"Pain"},{"key":"10.1016\/j.vascn.2012.04.006_bb0115","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.neuron.2007.07.016","article-title":"Nociceptors\u2014Noxious stimulus detectors","volume":"55","author":"Woolf","year":"2007","journal-title":"Neuron"}],"container-title":["Journal of Pharmacological and Toxicological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056871912000469?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056871912000469?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T23:56:39Z","timestamp":1761004599000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1056871912000469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S1056871912000469"],"URL":"https:\/\/doi.org\/10.1016\/j.vascn.2012.04.006","relation":{},"ISSN":["1056-8719"],"issn-type":[{"value":"1056-8719","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of manual and automated filaments for evaluation of neuropathic pain behavior in rats","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmacological and Toxicological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vascn.2012.04.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}