{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:18:46Z","timestamp":1787167126551,"version":"build-2736575974"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100031374","name":"Universidade do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100031374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","award":["12\/2022"],"award-info":[{"award-number":["12\/2022"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","award":["01\/2023"],"award-info":[{"award-number":["01\/2023"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmacological and Toxicological Methods"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.vascn.2025.108381","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T03:15:45Z","timestamp":1751426145000},"page":"108381","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Anticoagulant activity of Eucalyptus essential oils: An in vitro approach and a bioinformatics-based pharmacokinetic-pharmacodynamic analysis"],"prefix":"10.1016","volume":"135","author":[{"given":"Jhonatan Felipe","family":"dos Santos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Eduarda Dias","family":"Possate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maysa Barbosa de","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eveline Maria de","family":"Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Andrade","family":"Furtado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lays da Silva Moreira","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabela Cristina Gomes","family":"Hon\u00f3rio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio","family":"de Almeida-Junior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.vascn.2025.108381_bb0005","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.3390\/microorganisms12081538","article-title":"Effects of mint oils on the human oral microbiome: A pilot study","volume":"12","author":"Abdelrahman","year":"2024","journal-title":"Microorganisms"},{"issue":"5","key":"10.1016\/j.vascn.2025.108381_bb0010","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1093\/ehjcvp\/pvae052","article-title":"The search for the holy grail: The balance between the risk of thrombosis and bleeding in patients","volume":"10","author":"Agewall","year":"2024","journal-title":"European Heart Journal - Cardiovascular Pharmacotherapy"},{"issue":"31","key":"10.1016\/j.vascn.2025.108381_bb0015","doi-asserted-by":"crossref","first-page":"28233","DOI":"10.1021\/acsomega.3c01571","article-title":"Natural oils enhance the topical delivery of ketoconazole by nanoemulgel for fungal infections","volume":"8","author":"Ahmad","year":"2023","journal-title":"ACS Omega"},{"issue":"12","key":"10.1016\/j.vascn.2025.108381_bb0020","doi-asserted-by":"crossref","first-page":"3506","DOI":"10.3390\/molecules26123506","article-title":"The role of essential oils and their main compounds in the management of cardiovascular disease risk factors","volume":"26","author":"Alves-Silva","year":"2021","journal-title":"Molecules"},{"issue":"1","key":"10.1016\/j.vascn.2025.108381_bb0025","doi-asserted-by":"crossref","DOI":"10.1111\/jfbc.13566","article-title":"D-limonene: A multifunctional compound with potent therapeutic effects","volume":"45","author":"Anandakumar","year":"2021","journal-title":"Journal of Food Biochemistry"},{"issue":"4","key":"10.1016\/j.vascn.2025.108381_bb0030","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1007\/s10787-023-01237-6","article-title":"Anti-inflammatory mechanisms of eucalyptol rich Eucalyptus globulus essential oil alone and in combination with flurbiprofen","volume":"31","author":"Arooj","year":"2023","journal-title":"Inflammopharmacology"},{"issue":"5","key":"10.1016\/j.vascn.2025.108381_bb0035","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.thromres.2014.02.027","article-title":"The Kallikrein inhibitor from Bauhinia bauhinioides (BbKI) shows antithrombotic properties in venous and arterial thrombosis models","volume":"133","author":"Brito","year":"2014","journal-title":"Thrombosis Research"},{"key":"10.1016\/j.vascn.2025.108381_bb0040","article-title":"Natural products for antithrombosis","volume":"2015","author":"Chen","year":"2015","journal-title":"Evidence-based Complementary and Alternative Medicine"},{"issue":"1","key":"10.1016\/j.vascn.2025.108381_bb0045","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1186\/s12967-023-04233-0","article-title":"Uncovering the mechanism of resveratrol in the treatment of diabetic kidney disease based on network pharmacology, molecular docking, and experimental validation","volume":"21","author":"Chen","year":"2023","journal-title":"Journal of Translational Medicine"},{"issue":"4","key":"10.1016\/j.vascn.2025.108381_bb0050","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1590\/s1984-29612019090","article-title":"Anthelmintic activity of Eucalyptus citriodora essential oil and its major component, citronellal, on sheep gastrointestinal nematodes","volume":"28","author":"de Ara\u00fajo-Filho","year":"2019","journal-title":"Revista Brasileira de Parasitologia Veterin\u00e1ria"},{"issue":"1","key":"10.1016\/j.vascn.2025.108381_bb0055","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s12906-017-1598-2","article-title":"Chemical composition, vasorelaxant, antioxidant and antiplatelet effects of essential oil of Artemisia campestris L. from Oriental Morocco","volume":"17","author":"Dib","year":"2017","journal-title":"BMC Complementary and Alternative Medicine"},{"key":"10.1016\/j.vascn.2025.108381_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2019.152859","article-title":"Curdione inhibits thrombin-induced platelet aggregation via regulating the AMP-activated protein kinase-vinculin\/talin-integrin \u03b1IIb\u03b23 sign pathway","volume":"61","author":"Fang","year":"2019","journal-title":"Phytomedicine"},{"key":"10.1016\/j.vascn.2025.108381_bb0065","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1218315","article-title":"Eucalyptus-derived essential oils alleviate microbes and modulate inflammation by suppressing superoxide and elastase release","volume":"14","author":"Fayez","year":"2023","journal-title":"Frontiers in Pharmacology"},{"issue":"6","key":"10.1016\/j.vascn.2025.108381_bb0070","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.3390\/pharmaceutics14061120","article-title":"Drug-drug interactions of direct oral anticoagulants (DOACs): From pharmacological to clinical practice","volume":"14","author":"Ferri","year":"2022","journal-title":"Pharmaceutics"},{"issue":"8","key":"10.1016\/j.vascn.2025.108381_bb0075","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1007\/s40262-020-00879-x","article-title":"Drug-drug interactions with direct oral anticoagulants","volume":"59","author":"Foerster","year":"2020","journal-title":"Clinical Pharmacokinetics"},{"issue":"13","key":"10.1016\/j.vascn.2025.108381_bb0080","doi-asserted-by":"crossref","first-page":"4977","DOI":"10.3390\/molecules28134977","article-title":"Novel isosteviol-based FXa inhibitors: Molecular modeling, in silico design and docking simulation","volume":"28","author":"Gackowski","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.vascn.2025.108381_bb0085","doi-asserted-by":"crossref","first-page":"W270","DOI":"10.1093\/nar\/gkr366","article-title":"SwissDock, a protein-small molecule docking web service based on EADock DSS","volume":"39","author":"Grosdidier","year":"2011","journal-title":"Nucleic Acids Research"},{"issue":"12","key":"10.1016\/j.vascn.2025.108381_bb0090","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.3390\/ph16121669","article-title":"In vitro screening of antimicrobial and anti-coagulant activities, ADME profiling, and molecular docking study of Citrus limon L. and Citrus paradisi L. cold-pressed volatile oils","volume":"16","author":"Hamdi","year":"2023","journal-title":"Pharmaceuticals (Basel)"},{"issue":"1","key":"10.1016\/j.vascn.2025.108381_bb0095","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1080\/13880209.2017.1314513","article-title":"Anti-inflammatory activity of clove (Eugenia caryophyllata) essential oil in human dermal fibroblasts","volume":"55","author":"Han","year":"2017","journal-title":"Pharmaceutical Biology"},{"key":"10.1016\/j.vascn.2025.108381_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biopen.2017.04.001","article-title":"Chemical composition analysis and in vitro biological activities of ten essential oils in human skin cells","volume":"5","author":"Han","year":"2017","journal-title":"Biochimie Open"},{"key":"10.1016\/j.vascn.2025.108381_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.115467","article-title":"1,8-cineole (eucalyptol): A versatile phytochemical with therapeutic applications across multiple diseases","volume":"167","author":"Hoch","year":"2023","journal-title":"Biomedicine & Pharmacotherapy"},{"issue":"10","key":"10.1016\/j.vascn.2025.108381_bb0110","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1001\/archinte.165.10.1095","article-title":"Systematic overview of warfarin and its drug and food interactions","volume":"165","author":"Holbrook","year":"2005","journal-title":"Archives of Internal Medicine"},{"issue":"3","key":"10.1016\/j.vascn.2025.108381_bb0115","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1053\/rmed.2003.1432","article-title":"Anti-inflammatory activity of 1.8-cineol (eucalyptol) in bronchial asthma: A double-blind placebo-controlled trial","volume":"97","author":"Juergens","year":"2003","journal-title":"Respiratory Medicine"},{"issue":"2\u20133","key":"10.1016\/j.vascn.2025.108381_bb0120","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/minf.201000151","article-title":"QSAR modelling of rat acute toxicity on the basis of PASS prediction","volume":"30","author":"Lagunin","year":"2011","journal-title":"Molecular Informatics"},{"issue":"3","key":"10.1016\/j.vascn.2025.108381_bb0125","first-page":"391","article-title":"The effect of cytochrome P450 metabolism on drug response, interactions, and adverse effects","volume":"76","author":"Lynch","year":"2007","journal-title":"American Family Physician"},{"issue":"9","key":"10.1016\/j.vascn.2025.108381_bb0130","doi-asserted-by":"crossref","first-page":"2164","DOI":"10.1016\/j.bmcl.2016.03.068","article-title":"Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells","volume":"26","author":"Madadi","year":"2016","journal-title":"Bioorganic & Medicinal Chemistry Letters"},{"issue":"6","key":"10.1016\/j.vascn.2025.108381_bb0135","article-title":"Drug interactions affecting oral anticoagulant use","volume":"15","author":"Mar","year":"2022","journal-title":"Circulation: Arrhythmia and Electrophysiology"},{"key":"10.1016\/j.vascn.2025.108381_bb0140","author":"Mazumder"},{"issue":"22","key":"10.1016\/j.vascn.2025.108381_bb0145","doi-asserted-by":"crossref","first-page":"7101","DOI":"10.1182\/bloodadvances.2023010177","article-title":"American Society of Hematology 2023 guidelines for management of venous thromboembolism: Thrombophilia testing","volume":"7","author":"Middeldorp","year":"2023","journal-title":"Blood Advances"},{"issue":"1","key":"10.1016\/j.vascn.2025.108381_bb0150","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1177\/1076029615595879","article-title":"Antiplatelet and anticoagulant activities of angelica shikokiana extract and its isolated compounds","volume":"23","author":"Mira","year":"2017","journal-title":"Clinical and Applied Thrombosis\/Hemostasis"},{"issue":"1","key":"10.1016\/j.vascn.2025.108381_bb0155","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s00204-023-03616-y","article-title":"Evaluation of new alternative methods for the identification of estrogenic, androgenic and steroidogenic effects: A comparative in vitro\/in silico study","volume":"98","author":"Najjar","year":"2024","journal-title":"Archives of Toxicology"},{"issue":"6","key":"10.1016\/j.vascn.2025.108381_bb0160","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1742-7843.2006.pto_388.x","article-title":"Natural oils affect the human skin integrity and the percutaneous penetration of benzoic acid dose-dependently","volume":"98","author":"Nielsen","year":"2006","journal-title":"Basic and Clinical Pharmacology and Toxicology"},{"key":"10.1016\/j.vascn.2025.108381_bb0165","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/978-1-62703-059-5_2","article-title":"Accessing and using chemical databases","volume":"930","author":"Nikolov","year":"2013","journal-title":"Methods in Molecular Biology"},{"issue":"6","key":"10.1016\/j.vascn.2025.108381_bb0170","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1007\/s00210-020-02037-3","article-title":"Influence of renal insufficiency on anticoagulant effects and safety of warfarin in Chinese patients: Analysis from a randomized controlled trial","volume":"394","author":"Ning","year":"2021","journal-title":"Naunyn-Schmiedeberg\u2019s Archives of Pharmacology"},{"issue":"9","key":"10.1016\/j.vascn.2025.108381_bb0175","doi-asserted-by":"crossref","first-page":"3851","DOI":"10.3390\/molecules28093851","article-title":"New hybrid tetrahydropyrrolo[3,2,1-ij]quinolin-1-ylidene-2-thioxothiazolidin-4-ones as new inhibitors of factor Xa and factor XIa: Design, synthesis, and in silico and experimental evaluation","volume":"28","author":"Novichikhina","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.vascn.2025.108381_bb0180","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1146\/annurev-pharmtox-032823-122811","article-title":"Oral anticoagulants beyond warfarin","volume":"64","author":"Olie","year":"2024","journal-title":"Annual Review of Pharmacology and Toxicology"},{"issue":"3","key":"10.1016\/j.vascn.2025.108381_bb0185","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3390\/gels9030209","article-title":"Permeability-enhanced liposomal emulgel formulation of 5-fluorouracil for the treatment of skin cancer","volume":"9","author":"Pachauri","year":"2023","journal-title":"Gels"},{"issue":"2","key":"10.1016\/j.vascn.2025.108381_bb0190","doi-asserted-by":"crossref","DOI":"10.1590\/0001-3765202220200394","article-title":"Antifungal activity of essential oil from Eucalyptus staigeriana against Alternaria alternata causing of leaf spot and black rot in table grapes","volume":"94","author":"Pedrotti","year":"2022","journal-title":"Anais da Academia Brasileira de Ci\u00eancias"},{"issue":"9","key":"10.1016\/j.vascn.2025.108381_bb0195","doi-asserted-by":"crossref","first-page":"4066","DOI":"10.1021\/acs.jmedchem.5b00104","article-title":"pkCSM: Predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures","volume":"58","author":"Pires","year":"2015","journal-title":"Journal of Medicinal Chemistry"},{"key":"10.1016\/j.vascn.2025.108381_bb0200","article-title":"High-molecular-weight fractions of spruce and Eucalyptus lignin as a perspective nanoparticle-based platform for a therapy delivery in liver cancer","volume":"9","author":"Pylypchuk","year":"2021","journal-title":"Frontiers in Bioengineering and Biotechnology"},{"issue":"3","key":"10.1016\/j.vascn.2025.108381_bb0205","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.vetpar.2014.05.026","article-title":"Efficacy of free and nanoencapsulated Eucalyptus citriodora essential oils on sheep gastrointestinal nematodes and toxicity for mice","volume":"204","author":"Ribeiro","year":"2014","journal-title":"Veterinary Parasitology"},{"issue":"8","key":"10.1016\/j.vascn.2025.108381_bb0210","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.3390\/biom10081139","article-title":"Immunomodulatory activities of selected essential oils","volume":"10","author":"Sandner","year":"2020","journal-title":"Biomolecules"},{"key":"10.1016\/j.vascn.2025.108381_bb0215","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.ejphar.2016.07.005","article-title":"A comparison of two semi-mechanistic models for prolactin release and prediction of receptor occupancy following administration of dopamine D2 receptor antagonists in rats","volume":"789","author":"Taneja","year":"2016","journal-title":"European Journal of Pharmacology"},{"issue":"1","key":"10.1016\/j.vascn.2025.108381_bb0220","doi-asserted-by":"crossref","first-page":"46","DOI":"10.5713\/ajas.2013.13301","article-title":"Effects of Eucalyptus crude oils supplementation on rumen fermentation, microorganism and nutrient digestibility in swamp buffaloes","volume":"27","author":"Thao","year":"2014","journal-title":"Asian-Australasian Journal of Animal Sciences"},{"issue":"5","key":"10.1016\/j.vascn.2025.108381_bb0225","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1080\/14786419.2024.2332949","article-title":"Citronellal: A natural aldehyde with important properties","volume":"39","author":"Venancio","year":"2025","journal-title":"Natural Product Research"},{"issue":"4","key":"10.1016\/j.vascn.2025.108381_bb0230","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1093\/labmed\/lmx050","article-title":"Coagulation testing in the core laboratory","volume":"48","author":"Winter","year":"2017","journal-title":"Laboratory Medicine"},{"issue":"D1","key":"10.1016\/j.vascn.2025.108381_bb0235","doi-asserted-by":"crossref","first-page":"D1074","DOI":"10.1093\/nar\/gkx1037","article-title":"DrugBank 5.0: A major update to the DrugBank database for 2018","volume":"46","author":"Wishart","year":"2018","journal-title":"Nucleic Acids Research"},{"issue":"2","key":"10.1016\/j.vascn.2025.108381_bb0240","doi-asserted-by":"crossref","first-page":"165","DOI":"10.17219\/acem\/142657","article-title":"Anticoagulant-related nephropathy: Focus on novel agents. A review","volume":"31","author":"Zakrocka","year":"2022","journal-title":"Advances in Clinical and Experimental Medicine"},{"issue":"7","key":"10.1016\/j.vascn.2025.108381_bb0245","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1093\/ndt\/gfab197","article-title":"Epidemiology, thrombolytic management, and outcomes of acute stroke among patients with chronic kidney disease: A systematic review and meta-analysis","volume":"37","author":"Zamberg","year":"2022","journal-title":"Nephrology, Dialysis, Transplantation"},{"issue":"1","key":"10.1016\/j.vascn.2025.108381_bb0250","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/1755-5922.12230","article-title":"Cytochrome P450 2C9 gene polymorphism and warfarin maintenance dosage in pediatric patients: A systematic review and meta-analysis","volume":"35","author":"Zhang","year":"2017","journal-title":"Cardiovascular Therapeutics"},{"issue":"4","key":"10.1016\/j.vascn.2025.108381_bb0255","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1002\/jcc.24249","article-title":"Attracting cavities for docking. Replacing the rough energy landscape of the protein by a smooth attracting landscape","volume":"37","author":"Zoete","year":"2016","journal-title":"Journal of Computational Chemistry"}],"container-title":["Journal of Pharmacological and Toxicological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056871925008019?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056871925008019?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T20:19:19Z","timestamp":1760213959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1056871925008019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":51,"alternative-id":["S1056871925008019"],"URL":"https:\/\/doi.org\/10.1016\/j.vascn.2025.108381","relation":{},"ISSN":["1056-8719"],"issn-type":[{"value":"1056-8719","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anticoagulant activity of Eucalyptus essential oils: An in vitro approach and a bioinformatics-based pharmacokinetic-pharmacodynamic analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmacological and Toxicological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vascn.2025.108381","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108381"}}