{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T04:34:44Z","timestamp":1768278884207,"version":"3.49.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"3-4","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001823","name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy","doi-asserted-by":"publisher","award":["AVOZ 5020903"],"award-info":[{"award-number":["AVOZ 5020903"]}],"id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001824","name":"Grantov\u00e1 Agentura \u010cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["ME 580"],"award-info":[{"award-number":["ME 580"]}],"id":[{"id":"10.13039\/501100001824","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Immunology and Immunopathology"],"published-print":{"date-parts":[[2005,2]]},"DOI":"10.1016\/j.vetimm.2004.09.001","type":"journal-article","created":{"date-parts":[[2004,10,21]],"date-time":"2004-10-21T14:48:22Z","timestamp":1098370102000},"page":"155-161","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Protection of gnotobiotic pigs against Salmonella enterica serotype Typhimurium by rough mutant of the same serotype is accompanied by the change of local and systemic cytokine response"],"prefix":"10.1016","volume":"103","author":[{"given":"Igor","family":"\u0160pl\u00edchal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilja","family":"Trebichavsk\u00fd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alla","family":"\u0160pl\u00edchalov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul A.","family":"Barrow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetimm.2004.09.001_bib1","series-title":"Salmonella in Domestic Animals","first-page":"323","article-title":"Vaccination against Salmonella infections in food animals: rationale, theoretical basis and practical applications","author":"Barrow","year":"2000"},{"key":"10.1016\/j.vetimm.2004.09.001_bib2","doi-asserted-by":"crossref","first-page":"3432","DOI":"10.1016\/S0264-410X(01)00065-2","article-title":"The virulence for gnotobiotic pigs of live attenuated vaccine strains of Salmonella enterica serovars Typhimurium and Enteritidis","volume":"19","author":"Barrow","year":"2001","journal-title":"Vaccine"},{"key":"10.1016\/j.vetimm.2004.09.001_bib3","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1017\/S0950268800062063","article-title":"Inhibition of colonization of the chicken alimentary tract with Salmonella typhimurium gram-negative facultatively anaerobic bacteria","volume":"98","author":"Barrow","year":"1987","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.vetimm.2004.09.001_bib4","doi-asserted-by":"crossref","first-page":"5238","DOI":"10.1128\/iai.65.12.5238-5243.1997","article-title":"Pathogenicity and protective effect of rough mutants of Salmonella species in germ-free piglets","volume":"65","author":"Dlaba\u010d","year":"1997","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetimm.2004.09.001_bib5","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/S1286-4579(01)01479-4","article-title":"Cytokines in host defense against Salmonella","volume":"3","author":"Eckmann","year":"2001","journal-title":"Microb. Infect."},{"key":"10.1016\/j.vetimm.2004.09.001_bib6","series-title":"Salmonella in Domestic Animals","first-page":"191","article-title":"Salmonella infections in pigs","author":"Fedorka-Cray","year":"2000"},{"key":"10.1016\/j.vetimm.2004.09.001_bib7","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1128\/IAI.71.4.2182-2191.2003","article-title":"Rapid protection of gnotobiotic pigs against experimental salmonellosis following induction of polymorphonuclear leukocytes by avirulent Salmonella enterica","volume":"71","author":"Foster","year":"2003","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetimm.2004.09.001_bib8","series-title":"Salmonella in Domestic Animals","first-page":"245","article-title":"Public-health aspects of Salmonella infection","author":"Humphrey","year":"2000"},{"issue":"Pt 12","key":"10.1016\/j.vetimm.2004.09.001_bib9","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1099\/00221287-146-12-3217","article-title":"Differential cytokine expression in avian cells in response to invasion by Salmonella typhimurium, Salmonella enteritidis and Salmonella gallinarum","volume":"146","author":"Kaiser","year":"2000","journal-title":"Microbiology"},{"key":"10.1016\/j.vetimm.2004.09.001_bib10","doi-asserted-by":"crossref","first-page":"13681","DOI":"10.1073\/pnas.212488699","article-title":"Macrophage migration inhibitory factor (MIF) plays a pivotal role in immunity against Salmonella typhimurium","volume":"99","author":"Koebernick","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.vetimm.2004.09.001_bib11","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.2460\/ajvr.1991.52.11.1784","article-title":"Resistance to fecal shedding of salmonellae in pigs and chickens vaccinated with an aromatic-dependent mutant of Salmonella typhimurium","volume":"52","author":"Lumsden","year":"1991","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetimm.2004.09.001_bib12","series-title":"Immunology Methods Manual","first-page":"1544","article-title":"Rearing of germ-free piglets","author":"Mandel","year":"1997"},{"key":"10.1016\/j.vetimm.2004.09.001_bib13","first-page":"154","article-title":"Specificity of inhibition between Salmonella strains","volume":"109","author":"Martin","year":"2002","journal-title":"Dtsch. Tierarztl. Wochenschr."},{"key":"10.1016\/j.vetimm.2004.09.001_bib14","doi-asserted-by":"crossref","first-page":"393","DOI":"10.2174\/1566524023362492","article-title":"Immunity to systemic Salmonella infections","volume":"2","author":"Mastroeni","year":"2002","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.vetimm.2004.09.001_bib15","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1053\/tvjl.2000.0502","article-title":"Salmonella: immune responses and vaccines","volume":"161","author":"Mastroeni","year":"2001","journal-title":"Vet. J."},{"key":"10.1016\/j.vetimm.2004.09.001_bib16","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S1567-5769(03)00048-1","article-title":"Inflammatory mediator production in swine following endotoxin challenge with or without co-administration of dexamethasone","volume":"3","author":"Myers","year":"2003","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.vetimm.2004.09.001_bib17","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/S1286-4579(02)00020-5","article-title":"Polymorphonuclear leukocyte migration across model intestinal epithelia enhances Salmonella typhimurium killing via the epithelial derived cytokine IL-6","volume":"4","author":"Nadeau","year":"2002","journal-title":"Microb. Infect."},{"key":"10.1016\/j.vetimm.2004.09.001_bib18","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1128\/iai.64.3.849-854.1996","article-title":"Gamma interferon and interleukin-10 gene expression in innately susceptible and resistant mice during the early phase of Salmonella typhimurium infection","volume":"64","author":"Pie","year":"1996","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetimm.2004.09.001_bib19","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S1286-4579(01)01375-2","article-title":"Non-typhoidal salmonellosis: emerging problems","volume":"3","author":"Rabsch","year":"2001","journal-title":"Microb. Infect."},{"key":"10.1016\/j.vetimm.2004.09.001_bib20","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/S1286-4579(01)01486-1","article-title":"Bacterial virulence, proinflammatory cytokines and host immunity: how to choose the appropriate Salmonella vaccine strain?","volume":"3","author":"Raupach","year":"2001","journal-title":"Microb. Infect."},{"key":"10.1016\/j.vetimm.2004.09.001_bib21","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1081\/IAS-120020086","article-title":"Development and application of a pig IL-8 ELISA detection system","volume":"24","author":"\u0160pl\u00edchal","year":"2003","journal-title":"J. Immunoassay Immunochem."},{"key":"10.1016\/j.vetimm.2004.09.001_bib22","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1051\/vetres:2002017","article-title":"Early cytokine response of gnotobiotic piglets to Salmonella enterica serotype Typhimurium","volume":"33","author":"\u0160pl\u00edchal","year":"2002","journal-title":"Vet. Res."},{"key":"10.1016\/j.vetimm.2004.09.001_bib23","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.2460\/ajvr.1995.56.08.1012","article-title":"Tumor necrosis factor-alpha production in swine after oral or respiratory challenge exposure with live Salmonella typhimurium or Salmonella choleraesuis","volume":"56","author":"Stabel","year":"1995","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetimm.2004.09.001_bib24","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/BF02931375","article-title":"Systemic and local cytokine response of young piglets to oral infection with Salmonella enterica serotype Typhimurium","volume":"48","author":"Trebichavsk\u00fd","year":"2003","journal-title":"Folia Microbiol. (Praha)"},{"key":"10.1016\/j.vetimm.2004.09.001_bib25","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1084\/jem.188.9.1751","article-title":"Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells","volume":"188","author":"Utgaard","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.vetimm.2004.09.001_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/IAI.71.1.1-12.2003","article-title":"Molecular pathogenesis of Salmonella enterica serotype Typhimurium-induced diarrhea","volume":"71","author":"Zhang","year":"2003","journal-title":"Infect. Immun."}],"container-title":["Veterinary Immunology and Immunopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165242704002284?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165242704002284?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T07:19:11Z","timestamp":1759043951000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165242704002284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":26,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S0165242704002284"],"URL":"https:\/\/doi.org\/10.1016\/j.vetimm.2004.09.001","relation":{},"ISSN":["0165-2427"],"issn-type":[{"value":"0165-2427","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protection of gnotobiotic pigs against Salmonella enterica serotype Typhimurium by rough mutant of the same serotype is accompanied by the change of local and systemic cytokine response","name":"articletitle","label":"Article Title"},{"value":"Veterinary Immunology and Immunopathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetimm.2004.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}