{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T23:28:02Z","timestamp":1791156482628,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Immunology and Immunopathology"],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1016\/j.vetimm.2010.11.004","type":"journal-article","created":{"date-parts":[[2010,11,20]],"date-time":"2010-11-20T04:24:12Z","timestamp":1290227052000},"page":"23-29","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Prophylaxis of experimentally induced ovomucoid allergy in neonatal pigs using Lactococcus lactis"],"prefix":"10.1016","volume":"140","author":[{"given":"P.","family":"Rupa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Schmied","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.N.","family":"Wilkie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetimm.2010.11.004_bib0005","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.jaci.2009.02.030","article-title":"Mechanisms and treatment of allergic disease in the big picture of regulatory T-cells","volume":"123","author":"Akdis","year":"2009","journal-title":"J. Allergy Clin. Immun."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0010","first-page":"147","article-title":"Recent advances in the use of Lactococcus lactis as live recombinant vector for the development of new safe mucosal vaccines","volume":"8","author":"Berm\u00fadez-Humar\u00e1n","year":"2004","journal-title":"Recent Res. Dev. Microbiol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0015","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0165-2427(02)00293-3","article-title":"Control of immunoglobulin isotype production by porcine B-cells cultured with cytokines","volume":"91","author":"Crawley","year":"2003","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0020","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.1016\/S0264-410X(03)00142-7","article-title":"Porcine Ig isotypes: function and molecular characteristics","volume":"21","author":"Crawley","year":"2003","journal-title":"Vaccine"},{"key":"10.1016\/j.vetimm.2010.11.004_bib0025","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1016\/j.jaci.2007.03.023","article-title":"Acinetobacter lwoffii and Lactococcus lactis strains isolated from farm cowsheds possess strong allergy-protective properties","volume":"119","author":"Debarry","year":"2007","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0030","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.jaci.2006.12.615","article-title":"Oral administration of an IL-10-secreting Lactococcus lactis strain prevents food-induced IgE sensitization","volume":"119","author":"Frossard","year":"2007","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0035","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1079\/PNS2005466","article-title":"Probiotics and allergy","volume":"64","author":"Furrie","year":"2005","journal-title":"Proc. Nutr. Soc."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0040","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.imbio.2007.03.006","article-title":"Epidemiological and immunological evidence for the hygiene hypothesis","volume":"212","author":"Garn","year":"2007","journal-title":"Immunobiology"},{"key":"10.1016\/j.vetimm.2010.11.004_bib0045","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/ni0603-503","article-title":"TH1-TH2: a procrustean paradigm","volume":"4","author":"Gor","year":"2003","journal-title":"Nat. Immun."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-2164(04)56001-X","article-title":"Potential and opportunities for use of recombinant lactic acid bacteria in human health","volume":"56","author":"Hanniffy","year":"2004","journal-title":"Adv. Appl. Microbiol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0055","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.4049\/jimmunol.0802891","article-title":"Induction of antigen-specific tolerance by oral administration of Lactococcus lactis delivered immunodominant DQ8-restricted gliadin peptide in sensitized nonobese diabetic ab DQ8 transgenic mice","volume":"183","author":"Huibregtse","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0060","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1046\/j.1365-2222.2000.00943.x","article-title":"Probiotics in the management of atopic eczema","volume":"30","author":"Isolauri","year":"2000","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.vetimm.2010.11.004_bib0065","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/1741-7007-7-79","article-title":"Environmentally acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces","volume":"7","author":"Mulder","year":"2010","journal-title":"BMC Biol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0070","first-page":"102","article-title":"Heterologous protein production and delivery systems for Lactococcus lactis","volume":"2","author":"Nouaille","year":"2003","journal-title":"Genet. Mol. Res."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0075","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/mi.2009.131","article-title":"Neonatal mucosal immunization with a non-living, non-genetically modified Lactococcus lactis vaccine carrier induces systemic and local Th1-type immunity and protects against lethal bacterial infection","volume":"3","author":"Ramirez","year":"2010","journal-title":"Mucosal. Immunol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0080","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.vetimm.2005.05.008","article-title":"Toll-like receptor, MHCII, B7 and cytokine expression by porcine monocytes and monocyte-derived dendritic cells in response to microbial pathogen-associated molecular patterns","volume":"107","author":"Raymond","year":"2005","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0085","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.jaci.2003.11.025","article-title":"Immunologic influences on allergy and the TH1\/TH2 balance","volume":"113","author":"Romagnani","year":"2004","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0090","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1159\/000112498","article-title":"A neonatal swine model of allergy induced by the major food allergen chicken ovomucoid (Gal d1)","volume":"146","author":"Rupa","year":"2008","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0095","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.vetimm.2009.09.013","article-title":"Porcine allergy and IgE","volume":"132","author":"Rupa","year":"2009","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0100","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.vetimm.2009.09.019","article-title":"Attenuation of allergy to ovomucoid in pigs by neonatal treatment with heat-killed Escherichia coli or E. coli producing porcine IFN-\u03b3","volume":"132","author":"Rupa","year":"2009","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0105","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1002\/eji.200940045","article-title":"Role of Treg in immune regulation of allergic diseases","volume":"40","author":"Palomares","year":"2010","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0110","first-page":"805","article-title":"Update on food allergy","volume":"113","author":"Sampson","year":"2004","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0115","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1067\/mai.2000.104941","article-title":"Dose-response in double blind, placebo-controlled oral food challenges in children with atopic dermatitis","volume":"105","author":"Sicherer","year":"2000","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0120","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/nbt840","article-title":"Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10","volume":"21","author":"Steidler","year":"2003","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0125","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1172\/JCI25575","article-title":"IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking","volume":"116","author":"Strait","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.vetimm.2010.11.004_bib0130","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/BF00395939","article-title":"Lactic acid bacteria as vaccine delivery vehicles","volume":"70","author":"Wells","year":"2004","journal-title":"Antonie. Van. Leeuwenhoek."}],"container-title":["Veterinary Immunology and Immunopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165242710003867?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165242710003867?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T07:21:05Z","timestamp":1759044065000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165242710003867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":26,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["S0165242710003867"],"URL":"https:\/\/doi.org\/10.1016\/j.vetimm.2010.11.004","relation":{},"ISSN":["0165-2427"],"issn-type":[{"value":"0165-2427","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prophylaxis of experimentally induced ovomucoid allergy in neonatal pigs using Lactococcus lactis","name":"articletitle","label":"Article Title"},{"value":"Veterinary Immunology and Immunopathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetimm.2010.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}