{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T13:12:02Z","timestamp":1793020322786,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"3-4","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Immunology and Immunopathology"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.vetimm.2012.09.036","type":"journal-article","created":{"date-parts":[[2012,9,29]],"date-time":"2012-09-29T19:17:26Z","timestamp":1348946246000},"page":"198-205","source":"Crossref","is-referenced-by-count":20,"title":["Immune response of turbot (Scophthalmus maximus L.) to a broad spectrum vaccine candidate, recombinant glyceraldehyde-3-phosphate dehydrogenase of Edwardsiella tarda"],"prefix":"10.1016","volume":"150","author":[{"given":"Shunqing","family":"Liang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haizhen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingfan","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanxing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetimm.2012.09.036_bib0005","first-page":"447","article-title":"Potency testing of fish vaccines International Symposium on Fish Biologics: serodiagnostics and vaccines","volume":"49","author":"Amend","year":"1981","journal-title":"Dev. Biol. Stand."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0010","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1128\/IAI.72.4.2416-2419.2004","article-title":"Glyceraldehyde-3-phosphate dehydrogenase of Streptococcus pneumoniae is a surface-displayed plasminogen-binding protein","volume":"72","author":"Bergmann","year":"2004","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0015","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1006\/viro.1998.9322","article-title":"Combined DNA immunization with the glycoprotein gene of viral hemorrhagic septicemia virus and infectious hematopoietic necrosis virus induces double-specific protective immunity and nonspecific response in rainbow trout","volume":"249","author":"Boudinot","year":"1998","journal-title":"Virology"},{"key":"10.1016\/j.vetimm.2012.09.036_bib0020","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.fsi.2008.05.008","article-title":"Development of an effective Edwardsiella tarda vaccine for cultured turbot (Scophthalmus maximus)","volume":"25","author":"Castro","year":"2008","journal-title":"Fish. Shellfish. Immunol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0025","doi-asserted-by":"crossref","first-page":"2716","DOI":"10.1016\/j.vaccine.2010.01.023","article-title":"Analysis of the vaccine potential of a natural avirulent Edwardsiella tarda isolate","volume":"28","author":"Cheng","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.vetimm.2012.09.036_bib0030","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/j.jchromb.2009.03.048","article-title":"Purification of histidine-tagged nucleocapsid protein of Nipah virus using immobilized metal affinity chromatography","volume":"877","author":"Chong","year":"2009","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.vetimm.2012.09.036_bib0035","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.vetimm.2008.12.026","article-title":"Response of mucosal and systemic sIgM-positive cells in turbot (Scophthalmus maximus L.) immunization with Edwardsiella tarda","volume":"129","author":"Feng","year":"2009","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0040","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3923\/jbs.2009.392.401","article-title":"Effective inactivation of Edwardsiella tarda for the development of vaccine for fish","volume":"9","author":"Hossam","year":"2009","journal-title":"J. Bio. Sci."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0045","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1111\/j.1365-2761.2011.01275.x","article-title":"The immune response of turbot Scophthalmus maximus (L.), skin to high water temperature","volume":"34","author":"Huang","year":"2011","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0050","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1128\/JCM.29.9.1997-2001.1991","article-title":"Pathogenic properties of Edwardsiella species","volume":"29","author":"Janda","year":"1991","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0055","doi-asserted-by":"crossref","first-page":"5195","DOI":"10.1016\/j.vaccine.2009.06.071","article-title":"Construction and evaluation of DNA vaccines encoding Edwardsiella tarda antigens","volume":"27","author":"Jiao","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.vetimm.2012.09.036_bib0060","doi-asserted-by":"crossref","first-page":"3411","DOI":"10.1016\/j.vaccine.2004.02.026","article-title":"A conserved 37kDa outer membrane protein of Edwardsiella tarda is an effective vaccine candidate","volume":"22","author":"Kawai","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.vetimm.2012.09.036_bib0065","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.fsi.2005.08.005","article-title":"Protection of tilapia (Oreochromis mosambicus) from edwardsiellosis by vaccination with Edwardsiella tarda ghosts","volume":"20","author":"Kwon","year":"2006","journal-title":"Fish. Shellfish. Immunol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0070","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.fsi.2006.11.002","article-title":"Construction and characterization of a live, attenuated esrB mutant of Edwardsiella tarda and its potential as a vaccine against the haemorrhagic septicaemia in turbot, Scophthamus maximus (L.)","volume":"23","author":"Lan","year":"2007","journal-title":"Fish. Shellfish. Immunol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0075","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1016\/j.molimm.2007.10.003","article-title":"Transcriptional profiling of MHC class I genes in rainbow trout infected with infectious hematopoietic necrosis virus","volume":"45","author":"Landis","year":"2008","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1472-765X.2011.03164.x","article-title":"Secreted glyceraldehyde-3-phosphate dehydrogenase as a broad spectrum vaccine candidate against microbial infection in aquaculture","volume":"54","author":"Li","year":"2012","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0085","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.vetimm.2003.08.016","article-title":"Expression of immune response genes in rainbow trout skin induced by Gyrodactylus derjavini infections","volume":"97","author":"Lindenstrom","year":"2004","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0090","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1111\/j.1348-0421.2005.tb03652.x","article-title":"Vaccine efficacy of recombinant GAPDH of Edwardsielia tarda against edwardsiellosis","volume":"49","author":"Liu","year":"2005","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0095","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1016\/j.bbapap.2010.08.004","article-title":"Surface localized and extracellular Glyceraldehyde-3-phosphate dehydrogenase of Bacillus anthracis is a plasminogen binding protein","volume":"1804","author":"Matta","year":"2010","journal-title":"BBA-Proteins. Proteom."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0100","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1084\/jem.176.2.415","article-title":"A major surface protein on group A streptococci is a glyceraldehyde-3-phosphate-dehydrogenase with multiple binding activity","volume":"176","author":"Pancholi","year":"1992","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0105","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1007\/s002510000240","article-title":"Cloning, sequencing, and analysis of expression of a second IL-1\u03b2 gene in rainbow trout (Oncorhynchus mykiss)","volume":"51","author":"Pleguezuelos","year":"2000","journal-title":"Immunogenetics"},{"key":"10.1016\/j.vetimm.2012.09.036_bib0110","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.fsi.2008.03.019","article-title":"Cell markers and determinants in fish immunology","volume":"25","author":"Randelli","year":"2008","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0115","doi-asserted-by":"crossref","first-page":"431","DOI":"10.4014\/jmb.0807.404","article-title":"Role of alkaline serine protease, asp, in Vibrio alginolyticus virulence and regulation of its expression by luxO-luxR regulatory system","volume":"19","author":"Rui","year":"2009","journal-title":"J. Microbiol. Biotechnol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0120","doi-asserted-by":"crossref","first-page":"6344","DOI":"10.1016\/j.vaccine.2010.06.101","article-title":"Isolation and analysis of the vaccine potential of an attenuated Edwardsiella tarda strain","volume":"28","author":"Sun","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.vetimm.2012.09.036_bib0125","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/nri2858","article-title":"Antigen-presenting cell function in the tolerogenic liver environment","volume":"10","author":"Thomson","year":"2010","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0130","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.fsi.2005.04.006","article-title":"Effect of Achyranthes aspera on the immunity and survival of Labeo rohita infected with Aeromonas hydrophila","volume":"20","author":"Vasudeva Rao","year":"2006","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0135","doi-asserted-by":"crossref","first-page":"e7646","DOI":"10.1371\/journal.pone.0007646","article-title":"Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches","volume":"4","author":"Wang","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1016\/j.vetimm.2012.09.036_bib0140","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/j.fsi.2011.01.019","article-title":"QseBC controls flagellar motility, fimbrial hemagglutination and intracellular virulence in fish pathogen Edwardsiella tarda","volume":"30","author":"Wang","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0145","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1111\/j.1365-2672.2004.02387.x","article-title":"Complete sequence of virulence plasmid pEIB1 from the marine fish pathogen Vibrio anguillarum strain MVM425 and location of its replication region","volume":"97","author":"Wu","year":"2004","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0150","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1111\/j.1472-765X.2011.03126.x","article-title":"Search for live attenuated vaccine candidate against edwardsiellosis by mutating virulence-related genes of fish pathogen Edwardsiella tarda","volume":"53","author":"Xiao","year":"2011","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0155","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1365-2109.2008.02101.x","article-title":"Isolation and identification of fish pathogen Edwardsiella tarda from mariculture in China","volume":"40","author":"Xiao","year":"2008","journal-title":"Aquac. Res."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0160","first-page":"3849","article-title":"Edwardsiella tarda flagellar protein FlgD: a protective immunogen against edwardsiellosis","volume":"30","author":"Zhang","year":"2012","journal-title":"Vaccine 2012"},{"key":"10.1016\/j.vetimm.2012.09.036_bib0165","doi-asserted-by":"crossref","first-page":"3161","DOI":"10.1128\/AEM.67.7.3161-3167.2001","article-title":"Duplication of hemolysin genes in a virulent isolate of Vibrio harveyi","volume":"67","author":"Zhang","year":"2001","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.vetimm.2012.09.036_bib0170","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jbiotec.2009.12.010","article-title":"A novel multivalent vaccine based on secretary antigen-delivery induces protective immunity against Vibrio anguillarum and Aeromonas hydrophila","volume":"146","author":"Zhou","year":"2010","journal-title":"J. Biotechnol."}],"container-title":["Veterinary Immunology and Immunopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165242712003662?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165242712003662?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T08:18:30Z","timestamp":1594714710000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165242712003662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":34,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S0165242712003662"],"URL":"https:\/\/doi.org\/10.1016\/j.vetimm.2012.09.036","relation":{},"ISSN":["0165-2427"],"issn-type":[{"value":"0165-2427","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}