{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T19:39:24Z","timestamp":1794512364683,"version":"4.9.1"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100006370","name":"National Institute of Agricultural Biotechnology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006370","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010687","name":"Instituto Nacional de T\u00e9cnica Aeroespacial","doi-asserted-by":"publisher","award":["I111"],"award-info":[{"award-number":["I111"]}],"id":[{"id":"10.13039\/501100010687","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Immunology and Immunopathology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.vetimm.2026.111131","type":"journal-article","created":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T14:43:57Z","timestamp":1777733037000},"page":"111131","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Persistence of Campylobacter fetus subsp. venerealis in the reproductive tract of vaccinated heifers after experimental infection: Insights into vaginal mucosal immunity in heifers"],"prefix":"10.1016","volume":"298","author":[{"given":"Mar\u00eda Valeria","family":"Scioli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emiliano","family":"Sosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquin","family":"Barale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Azaldegui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra","family":"M\u00e9ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Paolicchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8047-6724","authenticated-orcid":false,"given":"Juan Agust\u00edn","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.vetimm.2026.111131_bib1","doi-asserted-by":"crossref","DOI":"10.1590\/0103-8478cr20190272","article-title":"Bovine genital campylobacteriosis: main features and perspectives for diagnosis and control","volume":"50","author":"Balzan","year":"2020","journal-title":"Cienc. Rural"},{"issue":"2","key":"10.1016\/j.vetimm.2026.111131_bib2","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.cvfa.2005.03.002","article-title":"Venereal diseases of cattle: natural history, diagnosis, and the role of vaccines in their control","volume":"21","author":"BonDurant","year":"2005","journal-title":"Vet. Clin. North Am. Food Anim. Pr."},{"issue":"4","key":"10.1016\/j.vetimm.2026.111131_bib3","doi-asserted-by":"crossref","first-page":"449","DOI":"10.2460\/ajvr.1988.49.04.449","article-title":"Vaccination of pregnant guinea pigs with Campylobacter fetus: effects of antigen dose, Campylobacter strain, and adjuvant type","volume":"49","author":"Bryner","year":"1988","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetimm.2026.111131_bib4","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.mimet.2016.11.012","article-title":"Assessing the intra-species genetic variability in the clonal pathogen Campylobacter fetus: CRISPRs are highly polymorphic DNA markers","volume":"132","author":"Calleros","year":"2017","journal-title":"J. Microbiol. Methods"},{"key":"10.1016\/j.vetimm.2026.111131_bib5","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1111\/j.1439-0450.2005.00834.x","article-title":"Immunohistochemical identification of Campylobacter fetus in natural cases of bovine and ovine abortions","volume":"52","author":"Campero","year":"2005","journal-title":"J. Vet. Med. B"},{"key":"10.1016\/j.vetimm.2026.111131_bib6","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/s11250-022-03237-0","article-title":"Spatial\u2013temporal trends and economic losses associated with bovine abortifacients in central Argentina","volume":"54","author":"Cant\u00f3n","year":"2022","journal-title":"Trop. Anim. Health Prod."},{"key":"10.1016\/j.vetimm.2026.111131_bib7","series-title":"Essentials of Veterinary Immunology and Immunopathology","first-page":"293","article-title":"Immunopathology of reproductive disorders of animals","author":"Chauhan","year":"2024"},{"issue":"24","key":"10.1016\/j.vetimm.2026.111131_bib8","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1136\/vr.134.24.628","article-title":"Persistence of Campylobacter fetus subspecies venerealis in experimentally infected heifers","volume":"134","author":"Cipolla","year":"1994","journal-title":"Vet. Rec."},{"issue":"10","key":"10.1016\/j.vetimm.2026.111131_bib9","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1111\/j.1751-0813.1977.tb05460.x","article-title":"A dual vaccine for the immunisation of cattle against vibriosis","volume":"53","author":"Clark","year":"1977","journal-title":"Aust. Vet. J."},{"issue":"3","key":"10.1016\/j.vetimm.2026.111131_bib10","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1128\/iai.10.3.422-429.1974","article-title":"Immunoglobulin classes and biological functions of Campylobacter (Vibrio) fetus antibodies in serum and cervicovaginal mucus","volume":"10","author":"Corbeil","year":"1974","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetimm.2026.111131_bib11","first-page":"729","article-title":"Immunity in the female bovine reproductive tract based on the response to Campylobacter fetus","volume":"137","author":"Corbeil","year":"1981","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.vetimm.2026.111131_bib12","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.theriogenology.2017.08.010","article-title":"Mucosal immunity of the postpartum bovine genital tract","volume":"104","author":"Dadarwal","year":"2017","journal-title":"Theriogenology"},{"issue":"4","key":"10.1016\/j.vetimm.2026.111131_bib13","doi-asserted-by":"crossref","first-page":"2929","DOI":"10.1007\/s42770-025-01768-w","article-title":"Evaluation of Campylobacter fetus subspecies concentrations in commercial bovine reproductive vaccines","volume":"56","author":"Dias","year":"2025","journal-title":"Braz. J. Microbiol."},{"key":"10.1016\/j.vetimm.2026.111131_bib14","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.7820","article-title":"L-cysteine transporter-PCR to detect hydrogen sulfide-producing Campylobacter fetus","volume":"7","author":"Farace","year":"2019","journal-title":"PeerJ"},{"key":"10.1016\/j.vetimm.2026.111131_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetimm.2024.110828","article-title":"Breed variability in the cellular mediated immune response to experimental Neospora caninum infection in heifers","volume":"276","author":"Fiorani","year":"2024","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"1","key":"10.1016\/j.vetimm.2026.111131_bib16","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s11259-023-10193-z","article-title":"Bovine campylobacteriosis in heifer: pathogenesis study and insights in the conventional and molecular diagnosis in an experimental bovine model and field cases","volume":"48","author":"Garc\u00eda","year":"2024","journal-title":"Vet. Res. Commun."},{"issue":"1","key":"10.1016\/j.vetimm.2026.111131_bib17","doi-asserted-by":"crossref","first-page":"029","DOI":"10.17352\/ijvsr.000011","article-title":"Bovine genital campylobacteriosis: a review","volume":"2","author":"Gard","year":"2016","journal-title":"Int. J. Vet. Sci. Res."},{"issue":"3","key":"10.1016\/j.vetimm.2026.111131_bib18","doi-asserted-by":"crossref","first-page":"149","DOI":"10.17533\/udea.rccp.v33n1a05","article-title":"Histopathological characterization of the reproductive organs of heifers experimentally infected with Campylobacter fetus venerealis","volume":"33","author":"Giobergia","year":"2020","journal-title":"Rev. Colomb. Cienc. Pecu."},{"issue":"9","key":"10.1016\/j.vetimm.2026.111131_bib19","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.2460\/javma.1971.158.09.1531","article-title":"Fertility and immune reaction of heifers vaccinated with an adjuvanted Vibrio fetus vaccine","volume":"158","author":"Kendrick","year":"1971","journal-title":"J. Am. Vet. Med. Assoc."},{"issue":"5","key":"10.1016\/j.vetimm.2026.111131_bib20","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/j.theriogenology.2015.10.037","article-title":"A review of sexually transmitted bovine trichomoniasis and campylobacteriosis affecting cattle reproductive health","volume":"85","author":"Michi","year":"2016","journal-title":"Theriogenology"},{"issue":"6","key":"10.1016\/j.vetimm.2026.111131_bib21","first-page":"732","article-title":"The estimation of the bactericidal power of the blood","volume":"38","author":"Miles","year":"1938","journal-title":"J. Hyg."},{"key":"10.1016\/j.vetimm.2026.111131_bib22","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.prevetmed.2018.10.022","article-title":"A retrospective epidemiological analysis of shared risk factors for bovine trichomoniasis and bovine genital campylobacteriosis in La Pampa province (Argentina)","volume":"161","author":"Molina","year":"2018","journal-title":"Prev. Vet. Med."},{"issue":"2","key":"10.1016\/j.vetimm.2026.111131_bib23","first-page":"96","article-title":"Positive cases of bovine genital campylobacteriosis and bovine trichomonosis in the eradication program of La Pampa, Argentina: 2008\u20132021. Trop. Anim","volume":"56","author":"Oyhenart","year":"2024","journal-title":"Health Prod."},{"issue":"4","key":"10.1016\/j.vetimm.2026.111131_bib24","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/S0093-691X(03)00236-X","article-title":"Epidemiology of Tritrichomonas foetus in beef bull populations in Florida","volume":"61","author":"Rae","year":"2004","journal-title":"Theriogenology"},{"key":"10.1016\/j.vetimm.2026.111131_bib25","series-title":"Bovine Reproduction","first-page":"717","article-title":"Infectious agents: Campylobacter","author":"Rush","year":"2021"},{"issue":"1","key":"10.1016\/j.vetimm.2026.111131_bib26","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1146\/annurev-animal-022516-022826","article-title":"Campylobacter-associated diseases in animals","volume":"5","author":"Sahin","year":"2017","journal-title":"Annu. Rev. Anim. Biosci."},{"issue":"2","key":"10.1016\/j.vetimm.2026.111131_bib27","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1128\/iai.11.2.245-251.1975","article-title":"Bovine venereal vibriosis: cure of genital infection in females by systemic immunization","volume":"11","author":"Schurig","year":"1975","journal-title":"Infect. Immun."},{"issue":"3","key":"10.1016\/j.vetimm.2026.111131_bib28","doi-asserted-by":"crossref","first-page":"R41","DOI":"10.1530\/REP-14-0163","article-title":"Innate immunity and inflammation of the bovine female reproductive tract in health and disease","volume":"148","author":"Sheldon","year":"2014","journal-title":"Reproduction"},{"issue":"3","key":"10.1016\/j.vetimm.2026.111131_bib29","doi-asserted-by":"crossref","first-page":"622","DOI":"10.21451\/1984-3143-AR1006","article-title":"Postpartum uterine infection and endometritis in dairy cattle","volume":"14","author":"Sheldon","year":"2018","journal-title":"Anim. Reprod."},{"key":"10.1016\/j.vetimm.2026.111131_bib30","doi-asserted-by":"crossref","first-page":"321","DOI":"10.3389\/fvets.2018.00321","article-title":"Diagnosis of bovine genital campylobacteriosis in South America","volume":"5","author":"Silveira","year":"2018","journal-title":"Front. Vet. Sci."},{"issue":"4","key":"10.1016\/j.vetimm.2026.111131_bib31","doi-asserted-by":"crossref","first-page":"3291","DOI":"10.1007\/s42770-023-01119-7","article-title":"A cross-sectional study on Campylobacter fetus subsp. venerealis prevalence and associated factors in Brazilian southern cattle farms","volume":"54","author":"Siqueira","year":"2023","journal-title":"Braz. J. Microbiol."},{"key":"10.1016\/j.vetimm.2026.111131_bib32","first-page":"531","article-title":"Skirrow agar for simultaneous isolation of Brucella and Campylobacter species","volume":"129","author":"Terzolo","year":"1991","journal-title":"Vet. Rec."},{"issue":"5","key":"10.1016\/j.vetimm.2026.111131_bib33","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1128\/IAI.01298-12","article-title":"Granule exocytosis of granulysin and granzyme B as a potential key mechanism in vaccine-induced immunity in cattle against the nematode Ostertagia ostertagi","volume":"81","author":"Van Meulder","year":"2013","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetimm.2026.111131_bib34","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s00284-001-0090-9","article-title":"Campylobacter fetus subspecies venerealis surface array protein from bovine isolates in Brazil","volume":"45","author":"de Vargas","year":"2002","journal-title":"Curr. Microbiol."},{"key":"10.1016\/j.vetimm.2026.111131_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.643206","article-title":"Bovine immunology: implications for dairy cattle","volume":"12","author":"Vlasova","year":"2021","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.vetimm.2026.111131_bib36","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/aji.12252","article-title":"Regulation of mucosal immunity in the female reproductive tract: the role of sex hormones in immune protection against sexually transmitted pathogens","volume":"72","author":"Wira","year":"2014","journal-title":"Am. J. Reprod. Immunol."}],"container-title":["Veterinary Immunology and Immunopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165242726000711?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165242726000711?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T08:02:41Z","timestamp":1784361761000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165242726000711"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":36,"alternative-id":["S0165242726000711"],"URL":"https:\/\/doi.org\/10.1016\/j.vetimm.2026.111131","relation":{},"ISSN":["0165-2427"],"issn-type":[{"value":"0165-2427","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Persistence of Campylobacter fetus subsp. venerealis in the reproductive tract of vaccinated heifers after experimental infection: Insights into vaginal mucosal immunity in heifers","name":"articletitle","label":"Article Title"},{"value":"Veterinary Immunology and Immunopathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetimm.2026.111131","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111131"}}