{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T07:29:39Z","timestamp":1785223779781,"version":"3.55.0"},"reference-count":118,"publisher":"Elsevier BV","issue":"3-4","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2006,3]]},"DOI":"10.1016\/j.vetmic.2005.11.009","type":"journal-article","created":{"date-parts":[[2005,12,15]],"date-time":"2005-12-15T18:00:20Z","timestamp":1134669620000},"page":"199-210","source":"Crossref","is-referenced-by-count":75,"title":["Functional analysis of bovine herpesvirus 1 (BHV-1) genes expressed during latency"],"prefix":"10.1016","volume":"113","author":[{"given":"C.","family":"Jones","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Geiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Henderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetmic.2005.11.009_bib1","doi-asserted-by":"crossref","first-page":"3644","DOI":"10.1128\/JVI.78.7.3644-3653.2004","article-title":"Both viral and host factors contribute to neurovirulence of bovine herpesvirus 1 and 5 in interferon receptor-deficient mice","volume":"78","author":"Abril","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib2","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1128\/JVI.76.2.717-729.2002","article-title":"Regions of the herpes simplex virus type 1 latency-associated transcript that protect cells from apoptosis in vitro and protect neuronal cells in vivo","volume":"76","author":"Ahmed","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib3","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1099\/0022-1317-80-8-2165","article-title":"Latency-associated transcript of equine herpesvirus 4 in trigeminal ganglia of naturally infected horses","volume":"80","author":"Borchers","year":"1999","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib4","doi-asserted-by":"crossref","first-page":"36596","DOI":"10.1074\/jbc.M300776200","article-title":"The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with an ubiquitinates p53","volume":"278","author":"Boutell","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vetmic.2005.11.009_bib5","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1128\/JVI.76.2.841-850.2002","article-title":"Herpes simplex virus type 1 immediate-early protein ICP0 and its isolated RING finger domain act as ubiquitin E3 ligases in vitro","volume":"76","author":"Boutell","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib6","first-page":"33","article-title":"Bovine respiratory disease: commercial vaccines currently available in Canada","volume":"41","author":"Bowland","year":"2000","journal-title":"Can. Vet. J."},{"key":"10.1016\/j.vetmic.2005.11.009_bib7","doi-asserted-by":"crossref","first-page":"4904","DOI":"10.1128\/JVI.71.7.4904-4914.1997","article-title":"The ICP0 protein of equine herpesvirus 1 is an early protein that independently transactivates expression of all classes of viral promoters","volume":"71","author":"Bowles","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib8","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1128\/JVI.74.3.1200-1208.2000","article-title":"Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein","volume":"74","author":"Bowles","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib9","doi-asserted-by":"crossref","first-page":"6099","DOI":"10.1128\/JVI.66.10.6099-6106.1992","article-title":"Localization of cis-acting sequences in the latency-related promoter of bovine herpesvirus 1 which are regulated by neuronal cell type factors and immediate-early genes","volume":"66","author":"Bratanich","year":"1992","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib10","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/0042-6822(92)90278-W","article-title":"The latency-related gene of bovine herpesvirus 1 inhibits the activity of immediate-early transcription unit 1","volume":"191","author":"Bratanich","year":"1992","journal-title":"Virology"},{"key":"10.1016\/j.vetmic.2005.11.009_bib11","doi-asserted-by":"crossref","first-page":"4898","DOI":"10.1128\/JVI.69.8.4898-4905.1995","article-title":"Gamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1","volume":"69","author":"Cantin","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib12","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1128\/JVI.63.4.1525-1530.1989","article-title":"Inhibition of T-lymphocyte mitogenic responses and effects on cell functions by bovine herpesvirus 1","volume":"63","author":"Carter","year":"1989","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib13","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2460\/ajvr.1995.56.01.45","article-title":"Investigation of pseudorabies virus DNA and RNA in trigeminal ganglia and tonsil tissues of latently infected swine","volume":"56","author":"Cheung","year":"1995","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2005.11.009_bib14","doi-asserted-by":"crossref","first-page":"9734","DOI":"10.1128\/JVI.73.12.9734-9740.1999","article-title":"The latency-related gene of bovine herpesvirus 1 inhibits programmed cell death","volume":"73","author":"Ciacci-Zanella","year":"1999","journal-title":"J. Virol."},{"issue":"Suppl. 1","key":"10.1016\/j.vetmic.2005.11.009_bib15","first-page":"6A","article-title":"The Holy Grail: immune control of human herpes simplex virus infection and disease","volume":"8","author":"Cunningham","year":"2001","journal-title":"Herpes"},{"key":"10.1016\/j.vetmic.2005.11.009_bib16","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0168-1702(97)00085-3","article-title":"Identification of DNA sequences in the latency related promoter of bovine herpes virus type 1 which are bound by neuronal specific factors","volume":"51","author":"Delhon","year":"1997","journal-title":"Virus Res."},{"key":"10.1016\/j.vetmic.2005.11.009_bib17","doi-asserted-by":"crossref","first-page":"7294","DOI":"10.1128\/JVI.72.9.7294-7301.1998","article-title":"Alternative splicing of the latency-related transcript of bovine herpesvirus 1 yields RNAs containing unique open reading frames","volume":"72","author":"Devireddy","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib18","doi-asserted-by":"crossref","first-page":"3778","DOI":"10.1128\/JVI.73.5.3778-3788.1999","article-title":"Activation of caspases and p53 by bovine herpesvirus 1 infection results in programmed cell death and efficient virus release","volume":"73","author":"Devireddy","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib19","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0022-2836(88)90521-9","article-title":"Analysis of the functional domains of herpes simplex virus type 1 immediate-early polypeptide Vmw110","volume":"202","author":"Everett","year":"1988","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib20","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1002\/1521-1878(200008)22:8<761::AID-BIES10>3.0.CO;2-A","article-title":"ICP0, a regulator of herpes simplex virus during lytic and latent infection","volume":"22","author":"Everett","year":"2000","journal-title":"Bioessays"},{"key":"10.1016\/j.vetmic.2005.11.009_bib21","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1006\/jmbi.1993.1657","article-title":"A novel arrangement of zinc-binding residues and secondary structure in the C3HC4 motif of an alpha herpes virus protein family","volume":"234","author":"Everett","year":"1993","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib22","doi-asserted-by":"crossref","first-page":"7339","DOI":"10.1128\/JVI.69.11.7339-7344.1995","article-title":"Point mutations in the herpes simplex virus type 1 Vmw110 RING finger helix affect activation of gene expression, viral growth, and interaction with PML-containing nuclear structures","volume":"69","author":"Everett","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib23","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1093\/emboj\/16.7.1519","article-title":"A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein","volume":"16","author":"Everett","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/j.vetmic.2005.11.009_bib24","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1093\/emboj\/18.6.1526","article-title":"Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110","volume":"18","author":"Everett","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/j.vetmic.2005.11.009_bib25","doi-asserted-by":"crossref","first-page":"4581","DOI":"10.1242\/jcs.112.24.4581","article-title":"Cell cycle regulation of PML modification and ND10 composition","volume":"112","author":"Everett","year":"1999","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.vetmic.2005.11.009_bib26","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1073\/pnas.022301899","article-title":"Spontaneous molecular reactivation of herpes simplex virus type 1 latency in mice","volume":"99","author":"Feldman","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.vetmic.2005.11.009_bib27","doi-asserted-by":"crossref","first-page":"3154","DOI":"10.1128\/JVI.68.5.3154-3162.1994","article-title":"Identification and zinc dependence of the bovine herpesvirus 1 transactivator protein BICP0","volume":"68","author":"Fraefel","year":"1994","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib28","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0896-6273(94)90276-3","article-title":"Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death","volume":"12","author":"Freeman","year":"1994","journal-title":"Neuron"},{"key":"10.1016\/j.vetmic.2005.11.009_bib29","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1128\/JCM.37.8.2498-2507.1999","article-title":"Detection of bovine herpesvirus type 1 in blood from naturally infected cattle by using a sensitive PCR that discriminates between wild-type virus and virus lacking glycoprotein E","volume":"37","author":"Fuchs","year":"1999","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib30","doi-asserted-by":"crossref","first-page":"2965","DOI":"10.1099\/0022-1317-83-12-2965","article-title":"The latency related (LR) gene of bovine herpes virus 1 (BHV-1) can inhibit the ability of bICP0 to activate productive infection","volume":"83","author":"Geiser","year":"2002","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib31","doi-asserted-by":"crossref","unstructured":"Geiser, V., Jones, C., 2005. The latency related gene encoded by bovine herpesvirus 1 encodes a small regulatory RNA that inhibits cell growth. J. Neurovirol., in press.","DOI":"10.1080\/13550280500385286"},{"key":"10.1016\/j.vetmic.2005.11.009_bib32","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1099\/vir.0.80921-0","article-title":"Characterization of a BHV-1 strain that does not express the major regulatory protein, bICP0","volume":"86","author":"Geiser","year":"2005","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib33","doi-asserted-by":"crossref","first-page":"2842","DOI":"10.1172\/JCI1130","article-title":"Cisplatin-induced apoptosis in rat dorsal root ganglion neurons is associated with attempted entry into the cell cycle","volume":"101","author":"Gill","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.vetmic.2005.11.009_bib34","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1089\/vim.1987.1.287","article-title":"T lymphocyte population dynamics and function following a primary bovine herpesvirus type-1 infection","volume":"1","author":"Griebel","year":"1987","journal-title":"Viral Immunol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib35","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1089\/vim.1987.1.267","article-title":"Bovine peripheral blood leukocyte subpopulation dynamics following a primary bovine herpesvirus-1 infection","volume":"1","author":"Griebel","year":"1987","journal-title":"Viral Immunol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib36","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1099\/0022-1317-71-2-369","article-title":"The interaction between bovine herpesvirus type 1 and activated bovine T lymphocytes","volume":"71","author":"Griebel","year":"1990","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib37","doi-asserted-by":"crossref","first-page":"3542","DOI":"10.4049\/jimmunol.157.8.3542","article-title":"Persistent cytokine expression in trigeminal ganglion latently infected with herpes simplex virus type 1","volume":"157","author":"Halford","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib38","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1089\/vim.1993.6.273","article-title":"Down regulation of murine MHC class I expression by bovine herpesvirus 1","volume":"6","author":"Hariharan","year":"1993","journal-title":"Viral Immunol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib39","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1099\/vir.0.80371-0","article-title":"The infected cell protein 0 encoded by bovine herpes virus 1 (bICP0) can activate caspase 3 when over-expressed in transfected cells","volume":"85","author":"Henderson","year":"2004","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib40","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1099\/vir.0.81109-0","article-title":"The bovine herpesvirus 1 (BHV-1) gene encoding infected cell protein 0 (bICP0) can inhibit interferon dependent transcription in the absence of other viral genes","volume":"86","author":"Henderson","year":"2005","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib41","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1242\/dev.121.8.2385","article-title":"The induction of multiple cell cycle events precedes target-related neuronal death","volume":"121","author":"Herrup","year":"1995","journal-title":"Development"},{"key":"10.1016\/j.vetmic.2005.11.009_bib42","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0168-1702(97)00128-7","article-title":"Bovine herpesvirus-1 infection affects the peptide transport activity in bovine cells","volume":"53","author":"Hinkley","year":"1998","journal-title":"Virus Res."},{"key":"10.1016\/j.vetmic.2005.11.009_bib43","doi-asserted-by":"crossref","first-page":"8245","DOI":"10.1128\/JVI.73.10.8245-8255.1999","article-title":"Perturbation of cell cycle progression and cellular gene expression as a function of herpes simplex virus ICP0","volume":"73","author":"Hobbs","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib44","doi-asserted-by":"crossref","first-page":"5345","DOI":"10.1128\/JVI.69.9.5345-5352.1995","article-title":"Identification of gene products encoded by the latency-related gene of bovine herpesvirus 1","volume":"69","author":"Hossain","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib45","doi-asserted-by":"crossref","first-page":"8507","DOI":"10.1128\/JVI.75.18.8507-8515.2001","article-title":"A mutation in the latency-related gene of bovine herpesvirus 1 leads to impaired ocular shedding in acutely infected calves","volume":"75","author":"Inman","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib46","doi-asserted-by":"crossref","first-page":"3636","DOI":"10.1128\/JVI.75.8.3636-3646.2001","article-title":"Region of herpes simplex virus type 1 latency-associated transcript sufficient for wild-type spontaneous reactivation promotes cell survival in tissue culture","volume":"75","author":"Inman","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib47","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1099\/0022-1317-82-3-483","article-title":"The zinc ring finger in the bICP0 protein encoded by bovine herpes virus-1 mediates toxicity and activates productive infection","volume":"82","author":"Inman","year":"2001","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib48","doi-asserted-by":"crossref","first-page":"6771","DOI":"10.1128\/JVI.76.13.6771-6779.2002","article-title":"A mutation in the latency related gene of bovine herpesvirus 1 interferes with the latency-reactivation cycle of latency in calves","volume":"76","author":"Inman","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib49","doi-asserted-by":"crossref","first-page":"5438","DOI":"10.1128\/JVI.78.10.5438-5447.2004","article-title":"Identification of a novel transcript containing a small open reading frame that is expressed during latency, and is antisense to the latency related gene of bovine herpes virus 1 (BHV-1)","volume":"78","author":"Inman","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib50","doi-asserted-by":"crossref","first-page":"8133","DOI":"10.1128\/JVI.72.10.8133-8142.1998","article-title":"A protein encoded by the latency-related gene of bovine herpesvirus 1 is expressed in trigeminal ganglionic neurons of latently infected cattle and interacts with cyclin-dependent kinase 2 during productive infection","volume":"72","author":"Jiang","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib51","doi-asserted-by":"crossref","first-page":"3184","DOI":"10.1128\/JVI.78.6.3184-3189.2004","article-title":"A mutation in the latency related gene of bovine herpesvirus 1 (BHV-1) inhibits protein expression of a protein from open reading frame 2 (ORF-2) and an adjacent reading frame during productive infection","volume":"78","author":"Jiang","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib52","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0065-3527(08)60784-8","article-title":"Alphaherpesvirus latency: its role in disease and survival of the virus in nature","volume":"51","author":"Jones","year":"1998","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.vetmic.2005.11.009_bib53","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1128\/JVI.64.3.1164-1170.1990","article-title":"Analysis of the transcriptional promoter which regulates the latency-related transcript of bovine herpesvirus 1","volume":"64","author":"Jones","year":"1990","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib54","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0952-7915(96)80033-1","article-title":"Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses","volume":"8","author":"Kagi","year":"1996","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib55","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1038\/nri888","article-title":"Viruses and interferon: fight for supremacy","volume":"2","author":"Katze","year":"2002","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib56","first-page":"787","article-title":"Recombinant bovine herpesvirus-1 (BHV-1) lacking transactivator protein BICPO entails lack of glycoprotein C and severely reduced infectivity","volume":"377","author":"Koppel","year":"1996","journal-title":"Biol. Chem."},{"key":"10.1016\/j.vetmic.2005.11.009_bib57","doi-asserted-by":"crossref","first-page":"5730","DOI":"10.1128\/JVI.64.12.5730-5737.1990","article-title":"Characterization of the latency-related transcriptionally active region of the bovine herpesvirus 1 genome","volume":"64","author":"Kutish","year":"1990","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib58","doi-asserted-by":"crossref","first-page":"7471","DOI":"10.1128\/JVI.70.11.7471-7477.1996","article-title":"Attenuation of DNA-dependent protein kinase activity and its catalytic subunit by the herpes simplex virus type 1 transactivator ICP0","volume":"70","author":"Lees-Miller","year":"1996","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib59","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S1097-2765(00)80055-6","article-title":"Cleavage of p21Cip1\/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade","volume":"1","author":"Levkau","year":"1998","journal-title":"Mol. Cell"},{"key":"10.1016\/j.vetmic.2005.11.009_bib60","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1128\/JVI.70.1.264-271.1996","article-title":"Inflammatory infiltration of the trigeminal ganglion after herpes simplex virus type 1 corneal infection","volume":"70","author":"Liu","year":"1996","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib61","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1084\/jem.191.9.1459","article-title":"CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons","volume":"191","author":"Liu","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.vetmic.2005.11.009_bib62","doi-asserted-by":"crossref","first-page":"11178","DOI":"10.1128\/JVI.75.22.11178-11184.2001","article-title":"Gamma interferon can prevent herpes simplex virus type 1 reactivation from latency in sensory neurons","volume":"75","author":"Liu","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib63","doi-asserted-by":"crossref","first-page":"8602","DOI":"10.1128\/JVI.71.11.8602-8614.1997","article-title":"Mutational analysis of the herpes simplex virus type 1 ICP0 C3HC4 zinc ring finger reveals a requirement for ICP0 in the expression of the essential alpha27 gene","volume":"71","author":"Lium","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib64","unstructured":"Lomonte, P., Seigneurin-Berny, D., Everett, R.D., Khochbin, S., Epstein, A.L., 2001. Presented at the 26th International Herpesvirus Workshop."},{"key":"10.1016\/j.vetmic.2005.11.009_bib65","doi-asserted-by":"crossref","first-page":"4848","DOI":"10.1128\/JVI.77.8.4848-4857.2003","article-title":"Infection of cattle with a bovine herpesvirus 1 (BHV-1) strain that contains a mutation in the latency related gene leads to increased apoptosis in trigeminal ganglia during the transition from acute infection to latency","volume":"77","author":"Lovato","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib66","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1099\/0022-1317-75-6-1223","article-title":"The nuclear location of PML, a cellular member of the C3HC4 zinc-binding domain protein family, is rearranged during herpes simplex virus infection by the C3HC4 viral protein ICP0","volume":"75","author":"Maul","year":"1994","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib67","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1099\/0022-1317-74-12-2679","article-title":"Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0)","volume":"74","author":"Maul","year":"1993","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib68","doi-asserted-by":"crossref","first-page":"10205","DOI":"10.1074\/jbc.271.17.10205","article-title":"Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases","volume":"271","author":"Meikrantz","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vetmic.2005.11.009_bib69","doi-asserted-by":"crossref","first-page":"3754","DOI":"10.1073\/pnas.91.9.3754","article-title":"Activation of cyclin A-dependent protein kinases during apoptosis","volume":"91","author":"Meikrantz","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.vetmic.2005.11.009_bib70","doi-asserted-by":"crossref","first-page":"11821","DOI":"10.1128\/JVI.75.23.11821-11826.2001","article-title":"Alpha and gamma interferons inhibit herpes simplex virus type 1 infection and spread in epidermal cells after axonal transmission","volume":"75","author":"Mikloska","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib71","doi-asserted-by":"crossref","first-page":"5209","DOI":"10.1128\/JVI.69.9.5209-5216.1995","article-title":"The bovine herpesvirus alpha gene trans-inducing factor activates transcription by mechanisms different from those of its herpes simplex virus type 1 counterpart VP16","volume":"69","author":"Misra","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib72","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1292\/jvms.61.375","article-title":"Detection of canine herpesvirus DNA in ganglionic neurons and the lymph node lymphocytes of latently infected dogs","volume":"61","author":"Miyoshi","year":"1999","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.vetmic.2005.11.009_bib73","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1128\/JVI.76.4.1995-1998.2002","article-title":"Herpes simplex virus ICP0 and ICP34.5 counteract distinct interferon-induced barriers to virus replication","volume":"76","author":"Mossman","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib74","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1128\/JVI.74.4.2052-2056.2000","article-title":"Herpes simplex virus ICP0 mutants are hypersensitive to interferon","volume":"74","author":"Mossman","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib75","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1128\/JVI.75.2.750-758.2001","article-title":"Herpes simplex virus triggers and then disarms a host antiviral response","volume":"75","author":"Mossman","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib76","doi-asserted-by":"crossref","first-page":"2975","DOI":"10.1099\/vir.0.19421-0","article-title":"The bovine herpesvirus 1 LR ORF2 is crucial for this gene's ability to restore the high reactivation phenotype to a Herpes simplex virus-1 LAT null mutant","volume":"84","author":"Mott","year":"2003","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib77","first-page":"165","article-title":"Detection of viral genome in non-neural tissues of cattle experimentally infected with bovine herpesvirus 1","volume":"44","author":"Mweene","year":"1996","journal-title":"Jpn. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2005.11.009_bib78","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1099\/0022-1317-68-3-825","article-title":"Different roles for L3T4+ and Lyt 2+ T cell subsets in the control of an acute herpes simplex virus infection of the skin and nervous system","volume":"68","author":"Nash","year":"1987","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib79","unstructured":"(NASS), N.A.S.S., 1996. Agricultural Statistics Board. U.S. Department of Agriculture."},{"key":"10.1016\/j.vetmic.2005.11.009_bib80","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1089\/vim.1997.10.21","article-title":"Bovine herpesvirus 1 downregulates the expression of bovine MHC class I molecules","volume":"10","author":"Nataraj","year":"1997","journal-title":"Viral Immunol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib81","doi-asserted-by":"crossref","first-page":"8161","DOI":"10.1074\/jbc.271.14.8161","article-title":"Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons","volume":"271","author":"Park","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vetmic.2005.11.009_bib82","doi-asserted-by":"crossref","first-page":"8975","DOI":"10.1523\/JNEUROSCI.17-23-08975.1997","article-title":"Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons","volume":"17","author":"Park","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.vetmic.2005.11.009_bib83","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1523\/JNEUROSCI.17-04-01256.1997","article-title":"G1\/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis","volume":"17","author":"Park","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.vetmic.2005.11.009_bib84","doi-asserted-by":"crossref","first-page":"10006","DOI":"10.1128\/JVI.74.21.10006-10017.2000","article-title":"Alphaherpesvirus proteins related to herpes simplex virus type 1 ICP0 affect cellular structures and proteins [In Process Citation]","volume":"74","author":"Parkinson","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib85","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1128\/JVI.73.1.650-657.1999","article-title":"Herpes simplex virus type 1 immediate-early protein vmw110 induces the proteasome-dependent degradation of the catalytic subunit of DNA-dependent protein kinase","volume":"73","author":"Parkinson","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib86","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1128\/JCM.43.1.393-401.2005","article-title":"Latency-realated gene encoded by bovine herpesvirus 1 promotes virus growth and reactivation from latrency in tonsils of infected calves","volume":"43","author":"Perez","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib87","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1126\/science.287.5457.1500","article-title":"Virus-induced neuronal apoptosis blocked by the herpes simplex virus latency-associated transcript (LAT)","volume":"287","author":"Perng","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.vetmic.2005.11.009_bib88","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1128\/JVI.76.3.1224-1235.2002","article-title":"A gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 latency-associated transcript gene and restore wild-type reactivation levels","volume":"76","author":"Perng","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib89","doi-asserted-by":"crossref","first-page":"3827","DOI":"10.1128\/JVI.61.12.3827-3831.1987","article-title":"Mapping bovine herpesvirus type 1 latency-related RNA in trigeminal ganglia of latently infected rabbits","volume":"61","author":"Rock","year":"1987","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib90","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1128\/JVI.66.4.2484-2490.1992","article-title":"Characterization of dexamethasone-induced reactivation of latent bovine herpesvirus 1","volume":"66","author":"Rock","year":"1992","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib91","first-page":"208","article-title":"Latent pseudorabies virus infection in pigs","volume":"20","author":"Sabo","year":"1976","journal-title":"Acta Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib92","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1128\/JVI.61.3.829-839.1987","article-title":"Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate early protein ICP0 exhibit impaired growth in cell culture","volume":"61","author":"Sacks","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib93","doi-asserted-by":"crossref","first-page":"3307","DOI":"10.1128\/JVI.72.4.3307-3320.1998","article-title":"Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins","volume":"72","author":"Samaniego","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib94","doi-asserted-by":"crossref","first-page":"6786","DOI":"10.1128\/JVI.71.9.6786-6795.1997","article-title":"Analysis of bovine herpesvirus 1 transcripts during a primary infection of trigeminal ganglia of cattle","volume":"71","author":"Schang","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib95","doi-asserted-by":"crossref","first-page":"3807","DOI":"10.1128\/JVI.70.6.3807-3814.1996","article-title":"The latency-related gene of bovine herpesvirus 1 encodes a product which inhibits cell cycle progression","volume":"70","author":"Schang","year":"1996","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib96","doi-asserted-by":"crossref","first-page":"974","DOI":"10.3181\/00379727-140-36592","article-title":"Reactivation of a bovine herpesvirus after corticosteroid treatment","volume":"140","author":"Sheffy","year":"1972","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.vetmic.2005.11.009_bib97","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0165-5728(95)00068-D","article-title":"Immune cell infiltration and persistence in the mouse trigeminal ganglion after infection of the cornea with herpes simplex virus type 1","volume":"61","author":"Shimeld","year":"1995","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib98","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1099\/0022-1317-77-5-977","article-title":"Immune cell infiltration in corneas of mice with recurrent herpes simplex virus disease","volume":"77","author":"Shimeld","year":"1996","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib99","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1099\/0022-1317-77-10-2583","article-title":"Reactivation of herpes simplex virus type 1 in the mouse trigeminal ganglion: an in vivo study of virus antigen and immune cell infiltration","volume":"77","author":"Shimeld","year":"1996","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib100","doi-asserted-by":"crossref","first-page":"3317","DOI":"10.1099\/0022-1317-78-12-3317","article-title":"Cytokine production in the nervous system of mice during acute and latent infection with herpes simplex virus type 1","volume":"78","author":"Shimeld","year":"1997","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib101","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/978-3-7091-6842-4_8","article-title":"Induction of mitosis-related genes during dopamine-triggered apoptosis in sympathetic neurons","volume":"50","author":"Shirvan","year":"1997","journal-title":"J. Neural Transm. Suppl."},{"key":"10.1016\/j.vetmic.2005.11.009_bib102","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1046\/j.1471-4159.1997.69020539.x","article-title":"Two waves of cyclin B and proliferating cell nuclear antigen expression during dopamine-triggered neuronal apoptosis","volume":"69","author":"Shirvan","year":"1997","journal-title":"J. Neurochem."},{"key":"10.1016\/j.vetmic.2005.11.009_bib103","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1023\/A:1022415611545","article-title":"Expression of cell cycle-related genes during neuronal apoptosis: is there a distinct pattern?","volume":"23","author":"Shirvan","year":"1998","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.vetmic.2005.11.009_bib104","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0952-7915(98)80227-6","article-title":"How do cytotoxic lymphocytes kill their targets?","volume":"10","author":"Shresta","year":"1998","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib105","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1084\/jem.175.5.1337","article-title":"Anti-CD8 impairs clearance of herpes simplex virus from the nervous system: implications for the fate of virally infected neurons","volume":"175","author":"Simmons","year":"1992","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.vetmic.2005.11.009_bib106","first-page":"31","article-title":"The role of immune mechanisms in control of herpes simplex virus infection of the peripheral nervous system","volume":"179","author":"Simmons","year":"1992","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib107","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1099\/0022-1317-67-12-2571","article-title":"Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate-early polypeptide Vmw110","volume":"67","author":"Stow","year":"1986","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib108","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0065-3527(08)60061-5","article-title":"Bovine herpesvirus 1 (BHV-1): biology, pathogenesis, and control","volume":"45","author":"Tikoo","year":"1995","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.vetmic.2005.11.009_bib109","doi-asserted-by":"crossref","first-page":"8815","DOI":"10.1073\/pnas.161283098","article-title":"The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity","volume":"98","author":"Van Sant","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.vetmic.2005.11.009_bib110","doi-asserted-by":"crossref","first-page":"8657","DOI":"10.1128\/JVI.73.10.8657-8668.1999","article-title":"Bovine herpesvirus 1 can infect CD4(+) T lymphocytes and induce programmed cell death during acute infection of cattle","volume":"73","author":"Winkler","year":"1999","journal-title":"J. Virol."},{"issue":"Pt. 12","key":"10.1016\/j.vetmic.2005.11.009_bib111","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.1099\/0022-1317-81-12-2993","article-title":"Analysis of cyclins in trigeminal ganglia of calves infected with bovine herpesvirus-1","volume":"81","author":"Winkler","year":"2000","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib112","doi-asserted-by":"crossref","first-page":"5337","DOI":"10.1128\/JVI.74.11.5337-5346.2000","article-title":"Persistence and reactivation of bovine herpesvirus-1 (BHV-1) in tonsils of latently infected cattle. Persistence and reactivation of bovine herpesvirus 1 in the tonsil of latently infected calves","volume":"74","author":"Winkler","year":"2000","journal-title":"J Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib113","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0378-1135(01)00498-9","article-title":"Analysis of bovine trigeminal ganglia following infection with bovine herpesvirus 1","volume":"86","author":"Winkler","year":"2002","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib114","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1128\/JVI.65.1.195-205.1991","article-title":"The three major immediate-early transcripts of bovine herpesvirus 1 arise from two divergent and spliced transcription units","volume":"65","author":"Wirth","year":"1991","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib115","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1128\/JVI.66.5.2763-2772.1992","article-title":"Immediate-early RNA 2.9 and early RNA 2.6 of bovine herpesvirus 1 are 3\u2019 coterminal and encode a putative zinc finger transactivator protein","volume":"66","author":"Wirth","year":"1992","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib116","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1128\/JVI.74.1.209-217.2000","article-title":"Immunohistochemical analysis of primary sensory neurons latently infected with herpes simplex virus type 1","volume":"74","author":"Yang","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib117","doi-asserted-by":"crossref","first-page":"9571","DOI":"10.1128\/JVI.75.20.9571-9578.2001","article-title":"The bovine herpesvirus 1 immediate-early protein (bICP0) associates with histone deacetylase 1 to activate transcription","volume":"75","author":"Zhang","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2005.11.009_bib118","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1099\/vir.0.80698-0","article-title":"Identification of functional domains within the bICP0 protein encoded by BHV-1","volume":"86","author":"Zhang","year":"2005","journal-title":"J. Gen. Virol."}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113505003688?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113505003688?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T19:35:06Z","timestamp":1706816106000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113505003688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3]]},"references-count":118,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["S0378113505003688"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2005.11.009","relation":{},"ISSN":["0378-1135"],"issn-type":[{"value":"0378-1135","type":"print"}],"subject":[],"published":{"date-parts":[[2006,3]]}}}