{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:07:09Z","timestamp":1791288429028,"version":"4.3.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"1-3","license":[{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2006,8]]},"DOI":"10.1016\/j.vetmic.2006.03.018","type":"journal-article","created":{"date-parts":[[2006,5,9]],"date-time":"2006-05-09T13:09:17Z","timestamp":1147180157000},"page":"138-148","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Evaluation of Erysipelothrix rhusiopathiae vaccines in pigs by intradermal challenge and immune responses"],"prefix":"10.1016","volume":"116","author":[{"given":"G.J.","family":"Eamens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.C.","family":"Chin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Turner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Barchia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetmic.2006.03.018_bib1","first-page":"69","article-title":"Swine erysipelas vaccine (inactivated)","volume":"14","author":"Anon","year":"2002","journal-title":"Pharmeuropa"},{"key":"10.1016\/j.vetmic.2006.03.018_bib2","series-title":"European Centre for the Validation of Alternative Methods Scientific Advisory Committee","article-title":"Statement on the validity of a serological method (ELISA) for the batch potency testing of inactivated swine erysipelas vaccines","author":"Balls","year":"2002"},{"key":"10.1016\/j.vetmic.2006.03.018_bib3","unstructured":"Blomer, A., 1992. Immunization of gilts against erysipelas and parvoviral infection with monovalent and bivalent vaccines. Thesis. Tierarztl. Hochsch., Hannover."},{"key":"10.1016\/j.vetmic.2006.03.018_bib4","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1111\/j.1751-0813.1988.tb16143.x","article-title":"Pathogenicity of field isolates of Erysipelothrix rhusiopathiae in mice, rats and pigs","volume":"65","author":"Eamens","year":"1988","journal-title":"Aust. Vet. J."},{"key":"10.1016\/j.vetmic.2006.03.018_bib5","unstructured":"Eamens, G.J., Forbes, W.A., Djordjevic S.P., in press. Characterisation of Erysipelothrix rhusiopathiae isolates from pigs associated with vaccine breakdowns. Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2006.03.018_bib6","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1574-695X.1995.tb00185.x","article-title":"Localization of viable bacteria and bacterial antigens in arthritic joints of Erysipelothrix rhusiopathiae-infected pigs","volume":"12","author":"Franz","year":"1995","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"10.1016\/j.vetmic.2006.03.018_bib7","series-title":"Replacement, Reduction and Refinement of Animal Experiments in the Development and Control of Biological Products. Proceedings of the Symposium Organised by the International Association of Biological Standardisation, November 1994","first-page":"43","article-title":"USDA in vitro tests: Erysipelothrix rhusiopathiae bacterin","author":"Goodman","year":"1996"},{"key":"10.1016\/j.vetmic.2006.03.018_bib8","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1017\/S0950268800049335","article-title":"Characterisation of a protective antigen of Erysipelothrix rhusiopathiae","volume":"107","author":"Groschup","year":"1991","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.vetmic.2006.03.018_bib9","first-page":"333","article-title":"Development of an enzyme-linked immunosorbent assay for potency testing of erysipelas bacterins","volume":"86","author":"Henderson","year":"1996","journal-title":"Dev. Biol. Stand."},{"key":"10.1016\/j.vetmic.2006.03.018_bib10","series-title":"Proceedings of the International Conference on Humane Endpoints in Animal Experiments for Biomedical Research","first-page":"102","article-title":"Use of clinical signs in efficacy testing of erysipelas vaccines","author":"Johannes","year":"1998"},{"key":"10.1016\/j.vetmic.2006.03.018_bib11","first-page":"694","article-title":"Prevention of atrophic rhinitis and enteric colibacillosis in swine: vaccination with an inactivated combination Escherichia coli\/Bordetella bronchiseptica bacterin","volume":"79","author":"McCarthy","year":"1984","journal-title":"Vet. Med."},{"key":"10.1016\/j.vetmic.2006.03.018_bib12","first-page":"1169","article-title":"Preventing atrophic rhinitis, erysipelas, and pasteurellosis in pigs","volume":"81","author":"McCarthy","year":"1986","journal-title":"Vet. Med."},{"key":"10.1016\/j.vetmic.2006.03.018_bib13","first-page":"7","article-title":"Dynamics of formation of immunity to leptospirosis in pigs inoculated with combined vaccine against swine fever, erysipelas and leptospirosis","volume":"25","author":"Petrov","year":"1972","journal-title":"Uchenye Zapiski Vitebskogo Veterinarogo Veterinarnogo Instituta"},{"key":"10.1016\/j.vetmic.2006.03.018_bib14","series-title":"Veterinary Medicine: A Textbook of the Diseases of Cattle, Sheep, Pigs, Goats and Horses","article-title":"Diseases caused by bacteria-1; erysipelas in swine","author":"Radostits","year":"2000"},{"key":"10.1016\/j.vetmic.2006.03.018_bib15","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1136\/vr.142.22.612","article-title":"Cross protection against Erysipelothrix rhusiopathiae serotype 10 induced by a serotype 1 and 2 vaccine","volume":"142","author":"Redhead","year":"1998","journal-title":"Vet. Rec."},{"key":"10.1016\/j.vetmic.2006.03.018_bib16","first-page":"123","article-title":"Potency testing of swine erysipelas vaccines by serology\u2014results of a pre-validation study","volume":"16","author":"Rosskopf-Streicher","year":"1999","journal-title":"Altex"},{"key":"10.1016\/j.vetmic.2006.03.018_bib17","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1016\/S0264-410X(00)00346-7","article-title":"Quality control of inactivated erysipelas vaccines: results of an international collaborative study to establish a new regulatory test","volume":"19","author":"Rosskopf-Streicher","year":"2001","journal-title":"Vaccine"},{"key":"10.1016\/j.vetmic.2006.03.018_bib18","unstructured":"Rosskopf-Streicher, U., Johannes, S., Gyra, H., Beckman, R., Cussler, K., 2002. Batch potency testing of inactivated erysipelas vaccine by ELISA\u2013development, validation and implementation. In: Developments in Biologicals, vol III. Karger AG, Basel, pp. 153\u2013158."},{"key":"10.1016\/j.vetmic.2006.03.018_bib19","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0378-1135(95)92533-H","article-title":"Protective activity and antigenic analysis of fractions of culture filtrates of Erysipelothrix rhusiopathiae","volume":"43","author":"Sato","year":"1995","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2006.03.018_bib20","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1111\/j.1439-0450.1998.tb00810.x","article-title":"Use of the protective antigen of Erysipelothrix rhusiopathiae in the enzyme-linked immunosorbent assay and latex agglutination","volume":"45","author":"Sato","year":"1998","journal-title":"J. Vet. Med. Ser. B"},{"key":"10.1016\/j.vetmic.2006.03.018_bib21","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1292\/jvms1939.41.593","article-title":"Response of growth agglutinating antibody and protection of pigs inoculated with swine erysipelas live vaccine","volume":"41","author":"Sawada","year":"1979","journal-title":"Jpn. J. Vet. Sci."},{"key":"10.1016\/j.vetmic.2006.03.018_bib22","doi-asserted-by":"crossref","first-page":"81","DOI":"10.2460\/ajvr.1987.48.01.81","article-title":"Cross protection of mice and swine given live-organism vaccine against challenge exposure with strains of Erysipelothrix rhusiopathiae representing ten serovars","volume":"48","author":"Sawada","year":"1987","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2006.03.018_bib23","doi-asserted-by":"crossref","first-page":"239","DOI":"10.2460\/ajvr.1987.48.02.239","article-title":"Cross protection of mice and swine inoculated with culture filtrate of attenuated Erysipelothrix rhusiopathiae and challenge exposed to strains of different serovars","volume":"48","author":"Sawada","year":"1987","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2006.03.018_bib24","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1128\/iai.64.5.1789-1793.1996","article-title":"Intracellular survival and replication of Erysipelothrix rhusiopathiae within murine macrophages: failure of induction of the oxidative burst of macrophages","volume":"64","author":"Shimoji","year":"1996","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetmic.2006.03.018_bib25","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1128\/IAI.67.4.1646-1651.1999","article-title":"Immunological characterisation of a protective antigen of Erysipelothrix rhusiopathiae: identification of the region responsible for protective immunity","volume":"67","author":"Shimoji","year":"1999","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetmic.2006.03.018_bib26","first-page":"9","article-title":"Relationship between growth agglutination titre of the IgM fraction of serum and protection in pigs immunised with swine erysipelas live vaccine","volume":"18","author":"Takahashi","year":"1981","journal-title":"Annu. Rep. Nat. Vet. Assoc. Lab."},{"key":"10.1016\/j.vetmic.2006.03.018_bib27","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.2460\/ajvr.1984.45.10.2115","article-title":"Cross protection in mice and swine immunised with live erysipelas vaccine to challenge exposure with strains of Erysipelothrix rhusiopathiae of various serotypes","volume":"45","author":"Takahashi","year":"1984","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2006.03.018_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1292\/jvms1939.47.1","article-title":"Pathogenicity of Erysipelothrix rhusiopathiae strains of serovars 1a, 3, 5, 6, 8, 11, 21 and type N isolated from slaughter pigs affected with chronic swine erysipelas","volume":"47","author":"Takahashi","year":"1985","journal-title":"Jpn. J. Vet. Sci."},{"key":"10.1016\/j.vetmic.2006.03.018_bib29","doi-asserted-by":"crossref","first-page":"795","DOI":"10.2460\/ajvr.1979.40.06.795","article-title":"Specificity in response of vaccinated swine and mice to challenge exposure with strains of Erysipelothrix rhusiopathiae of various serotypes","volume":"40","author":"Wood","year":"1979","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2006.03.018_bib30","doi-asserted-by":"crossref","first-page":"608","DOI":"10.2460\/ajvr.1981.42.04.608","article-title":"Susceptibility of vaccinated swine and mice to generalized infection with specific serotypes of Erysipelothrix rhusiopathiae","volume":"42","author":"Wood","year":"1981","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2006.03.018_bib31","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.2460\/ajvr.1972.33.08.1611","article-title":"Isolation of Erysipelothrix rhusiopathiae from soil and manure of swine-raising premises","volume":"33","author":"Wood","year":"1972","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2006.03.018_bib32","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1046\/j.1439-0450.1999.00207.x","article-title":"Protective activity of the purified protein antigen Erysipelothrix rhusiopathiae in pigs","volume":"46","author":"Yamazaki","year":"1999","journal-title":"J. Vet. Med. Ser. B"}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113506001283?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113506001283?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T22:56:00Z","timestamp":1759877760000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113506001283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8]]},"references-count":32,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["S0378113506001283"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2006.03.018","relation":{},"ISSN":["0378-1135"],"issn-type":[{"value":"0378-1135","type":"print"}],"subject":[],"published":{"date-parts":[[2006,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of Erysipelothrix rhusiopathiae vaccines in pigs by intradermal challenge and immune responses","name":"articletitle","label":"Article Title"},{"value":"Veterinary Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetmic.2006.03.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown copyright \u00a9 2006 Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}