{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T13:51:29Z","timestamp":1775742689108,"version":"3.50.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"3-4","license":[{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1016\/j.vetmic.2007.04.042","type":"journal-article","created":{"date-parts":[[2007,5,4]],"date-time":"2007-05-04T15:24:19Z","timestamp":1178292259000},"page":"382-386","source":"Crossref","is-referenced-by-count":12,"title":["Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis"],"prefix":"10.1016","volume":"124","author":[{"given":"John A.","family":"Angelos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise M.","family":"Ball","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetmic.2007.04.042_bib1","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.2460\/ajvr.2001.62.1222","article-title":"Cloning and characterization of a Moraxella bovis cytotoxin gene","volume":"62","author":"Angelos","year":"2001","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib2","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0378-1135(02)00410-8","article-title":"An RTX operon in hemolytic Moraxella bovis is absent from nonhemolytic strains","volume":"92","author":"Angelos","year":"2003","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2007.04.042_bib3","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.vaccine.2004.06.025","article-title":"Prevention of naturally occurring infectious bovine keratoconjunctivitis with a recombinant Moraxella bovis cytotoxin-ISCOM matrix adjuvanted vaccine","volume":"23","author":"Angelos","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.vetmic.2007.04.042_bib4","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0034-5288(18)31752-1","article-title":"Adherence of Moraxella bovis to cell cultures of bovine origin","volume":"39","author":"Annuar","year":"1985","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.vetmic.2007.04.042_bib5","doi-asserted-by":"crossref","first-page":"4875","DOI":"10.1128\/jb.176.16.4875-4882.1994","article-title":"Characterization of pilin genes from seven serologically defined prototype strains of Moraxella bovis","volume":"176","author":"Atwell","year":"1994","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.vetmic.2007.04.042_bib6","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0378-1135(94)90074-4","article-title":"Reproduction of bovine keratoconjunctivitis with a purified haemolytic and cytotoxic fraction of Moraxella bovis","volume":"42","author":"Beard","year":"1994","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2007.04.042_bib7","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1574-6968.1994.tb07263.x","article-title":"A haemolytic cell-free preparation of Moraxella bovis confers protection against infectious bovine keratoconjunctivitis","volume":"124","author":"Billson","year":"1994","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.vetmic.2007.04.042_bib8","doi-asserted-by":"crossref","first-page":"977","DOI":"10.2460\/ajvr.2004.65.977","article-title":"Stability, antigenicity, and aggregation of Moraxella bovis cytolysin after purification and storage","volume":"65","author":"George","year":"2004","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib9","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0378-1135(94)00084-A","article-title":"Partial characterization of a Moraxella bovis cytolysin","volume":"43","author":"Gray","year":"1995","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2007.04.042_bib10","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.2460\/ajvr.2001.62.1279","article-title":"Detection of shared magnetic antigenic determinants on whole Moraxella bovis pili by use of antisera to cyanogen bromide-cleaved M. bovis pilus protein","volume":"62","author":"Greene","year":"2001","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib11","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0378-1135(01)00317-0","article-title":"Immunoblot analysis of cyanogen bromide-cleaved Moraxella bovis pilin reveals presence of shared antigenic determinants on pili from heterologous strains","volume":"80","author":"Greene","year":"2001","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2007.04.042_bib12","first-page":"761","article-title":"Infectious bovine keratoconjunctivitis. I. Etiology","volume":"21","author":"Henson","year":"1960","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib13","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1099\/jmm.0.46366-0","article-title":"The Moraxella bovis RTX toxin locus mbx defines a pathogenicity island","volume":"55","author":"Hess","year":"2006","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.vetmic.2007.04.042_bib14","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2460\/ajvr.1990.51.02.191","article-title":"Comparative characterization of the leukocidic and hemolytic activity of Moraxella bovis","volume":"51","author":"Hoien-Dalen","year":"1990","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib15","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.3109\/02713688409000809","article-title":"In vitro adherence of Moraxella bovis to intact corneal epithelium","volume":"3","author":"Jackman","year":"1984","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib16","first-page":"2217","article-title":"Pathogenicity and immunogenicity of piliated and nonpiliated phases of Moraxella bovis in calves","volume":"47","author":"Jayappa","year":"1986","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib17","first-page":"18","article-title":"Effects of Moraxella bovis and culture filtrates on 51Cr-labeled bovine neutrophils","volume":"50","author":"Kagonyera","year":"1989","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib18","first-page":"10","article-title":"Cytopathic effects of Moraxella bovis on cultured bovine neutrophils and corneal epithelial cells","volume":"50","author":"Kagonyera","year":"1989","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib19","first-page":"618","article-title":"Economic impact of infectious bovine keratoconjunctivitis in beef calves","volume":"72","author":"Killinger","year":"1977","journal-title":"Vet. Med. Small Anim. Clin."},{"key":"10.1016\/j.vetmic.2007.04.042_bib20","first-page":"484","article-title":"Serologic and protective characterization of Moraxella bovis pili","volume":"75","author":"Lehr","year":"1985","journal-title":"Cornell Vet."},{"key":"10.1016\/j.vetmic.2007.04.042_bib21","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/j.1751-0813.1988.tb14513.x","article-title":"Vaccination against infectious bovine keratoconjunctivitis: protective efficacy and antibody response induced by pili of homologous and heterologous strains of Moraxella bovis","volume":"65","author":"Lepper","year":"1988","journal-title":"Aust. Vet. J."},{"key":"10.1016\/j.vetmic.2007.04.042_bib22","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0378-1135(94)00123-E","article-title":"The protective efficacy of cloned Moraxella bovis pili in monovalent and multivalent vaccine formulations against experimentally induced infectious bovine keratoconjunctivitis (IBK)","volume":"45","author":"Lepper","year":"1995","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2007.04.042_bib23","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0378-1135(93)90138-W","article-title":"A Moraxella bovis pili vaccine produced by recombinant DNA technology for the prevention of infectious bovine keratoconjunctivitis","volume":"36","author":"Lepper","year":"1993","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2007.04.042_bib24","doi-asserted-by":"crossref","first-page":"3032","DOI":"10.1128\/jb.170.7.3032-3039.1988","article-title":"Pilin-gene phase variation of Moraxella bovis is caused by an inversion of the pilin genes","volume":"170","author":"Marrs","year":"1988","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.vetmic.2007.04.042_bib25","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0378-1135(91)90111-R","article-title":"A unified serotyping scheme for Moraxella bovis","volume":"29","author":"Moore","year":"1991","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2007.04.042_bib26","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1751-0813.1989.tb03012.x","article-title":"Attachment of Moraxella bovis to calf corneal cells and inhibition by antiserum","volume":"66","author":"Moore","year":"1989","journal-title":"Aust. Vet. J."},{"key":"10.1016\/j.vetmic.2007.04.042_bib27","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1292\/jvms1939.41.363","article-title":"Hemolytic activity of Moraxella bovis","volume":"41","author":"Nakazawa","year":"1979","journal-title":"Nippon Juigaku Zasshi"},{"key":"10.1016\/j.vetmic.2007.04.042_bib28","first-page":"1848","article-title":"Moraxella bovis hemolysin","volume":"45","author":"Ostle","year":"1984","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib29","first-page":"1011","article-title":"Immunogenicity of Moraxella bovis hemolysin","volume":"46","author":"Ostle","year":"1985","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib30","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1365-2958.1993.tb01119.x","article-title":"Q pili enhance the attachment of Moraxella bovis to bovine corneas in vitro","volume":"7","author":"Ruehl","year":"1993","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.vetmic.2007.04.042_bib31","doi-asserted-by":"crossref","first-page":"248","DOI":"10.2460\/ajvr.1993.54.02.248","article-title":"Infection rates, disease frequency, pilin gene rearrangement, and pilin expression in calves inoculated with Moraxella bovis pilin-specific isogenic variants","volume":"54","author":"Ruehl","year":"1993","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2007.04.042_bib32","doi-asserted-by":"crossref","first-page":"507","DOI":"10.2527\/2005.833507x","article-title":"Genetic and environmental factors associated with incidence of infectious bovine keratoconjunctivitis in preweaned beef calves","volume":"83","author":"Snowder","year":"2005","journal-title":"J. Anim. Sci."}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113507002246?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113507002246?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T03:24:39Z","timestamp":1707881079000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113507002246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":32,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["S0378113507002246"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2007.04.042","relation":{},"ISSN":["0378-1135"],"issn-type":[{"value":"0378-1135","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10]]}}}