{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T23:47:04Z","timestamp":1790034424687,"version":"4.0.1"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.vetmic.2015.11.028","type":"journal-article","created":{"date-parts":[[2015,11,24]],"date-time":"2015-11-24T11:38:42Z","timestamp":1448365122000},"page":"130-137","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"special_numbering":"C","title":["Molecular characterisation of extended-spectrum \u03b2-lactamase (ESBL)-producing Escherichia coli isolates from hospital and ambulatory patients in Germany"],"prefix":"10.1016","volume":"200","author":[{"given":"Michael","family":"Pietsch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Eller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constanze","family":"Wendt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Holfelder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Falgenhauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelika","family":"Fruth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Gr\u00f6ssl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasmus","family":"Leistner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Valenza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido","family":"Werner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Pfeifer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetmic.2015.11.028_bib0005","doi-asserted-by":"crossref","first-page":"6385","DOI":"10.1128\/AAC.01604-13","article-title":"Molecular epidemiology of Escherichia coli sequence type 131 and its H30 and H30-Rx subclones among extended-spectrum-beta-lactamase-positive and -negative E. coli clinical isolates from the Chicago Region, 2007 to 2010","volume":"57","author":"Banerjee","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0010","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1089\/cmb.2012.0021","article-title":"SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing","volume":"19","author":"Bankevich","year":"2012","journal-title":"J. Comput. Biol."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0015","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1093\/jac\/dkp122","article-title":"Molecular epidemiology of Escherichia coli producing extended-spectrum {beta}-lactamases in Lugo (Spain): dissemination of clone O25b:H4-ST131 producing CTX-M-15","volume":"63","author":"Blanco","year":"2009","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0020","doi-asserted-by":"crossref","first-page":"O344","DOI":"10.1111\/1469-0691.12413","article-title":"Epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli in Sweden 2007\u20132011","volume":"20","author":"Brolund","year":"2014","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0025","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.ijmm.2013.02.001","article-title":"Plasmids and the spread of resistance","volume":"303","author":"Carattoli","year":"2013","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0030","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1111\/j.1469-0691.2010.03349.x","article-title":"Cephalosporin and fluoroquinolone combinations are highly associated with CTX-M beta-lactamase-producing Escherichia coli: a case\u2013control study in a French teaching hospital","volume":"17","author":"Cassier","year":"2011","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0035","doi-asserted-by":"crossref","first-page":"4555","DOI":"10.1128\/AEM.66.10.4555-4558.2000","article-title":"Rapid and simple determination of the Escherichia coli Phylogenetic Group","volume":"66","author":"Clermont","year":"2000","journal-title":"Appl. Environ. Microbiol."},{"issue":"Suppl. 1","key":"10.1016\/j.vetmic.2015.11.028_bib0040","doi-asserted-by":"crossref","first-page":"i57","DOI":"10.1093\/jac\/dkt027","article-title":"Molecular epidemiology of extended-spectrum beta-lactamase., AmpC beta-lactamase- and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae isolated from Canadian hospitals over a 5 year period: CANWARD 2007\u201311","volume":"68","author":"Denisuik","year":"2013","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0045","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1093\/jac\/dks124","article-title":"Characterization of Enterobacteriaceae producing OXA-48-like carbapenemases in the UK","volume":"67","author":"Dimou","year":"2012","journal-title":"J Antimicrob. Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0050","unstructured":"ECDC, 2013. Antimicrobial Resistance Surveillance in Europe 2012 Annual report of the European Antimicrobial resistance Surveillance Network (EARS-net) (Stockholm, ECDC)."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0055","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1093\/jac\/dkt163","article-title":"Presence of beta-lactamases in extended-spectrum-cephalosporin-resistant Salmonella enterica of 30 different serovars in Germany 2005\u201311","volume":"68","author":"Eller","year":"2013","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0060","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1093\/jac\/dkq004","article-title":"Emergence of human pandemic O25:H4-ST131CTX-M-15 extended-spectrum-beta-lactamase-producing Escherichia coli among companion animals","volume":"65","author":"Ewers","year":"2010","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0065","first-page":"782897","article-title":"Molecular characterization of ESBL-producing Enterobacteriaceae in northern Portugal","author":"Fernandes","year":"2014","journal-title":"Sci. World J."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0070","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1093\/jac\/dku270","article-title":"blaCTX-M-(1)(5)-carrying Escherichia coli and Salmonella isolates from livestock and food in Germany","volume":"69","author":"Fischer","year":"2014","journal-title":"J. Antimicrob. Chemother."},{"issue":"7","key":"10.1016\/j.vetmic.2015.11.028_bib0075","doi-asserted-by":"crossref","first-page":"e0134533","DOI":"10.1371\/journal.pone.0134533","article-title":"Molecular yyping of Enterobacteriaceae from pig holdings in North-Western Germany reveals extended-spectrum and AmpC \u03b2-lactamases producing but no carbapenem resistant ones","volume":"10","author":"Garc\u00eda-Cobos","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.vetmic.2015.11.028_bib0080","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1089\/mdr.2013.0109","article-title":"Characterization of plasmid-mediated beta-lactamases in fecal colonizing patients in the hospital and community setting in Spain","volume":"20","author":"Garrido","year":"2014","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0085","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1093\/jac\/dkr565","article-title":"Escherichia coli of human and avian origin: detection of clonal groups associated with fluoroquinolone and multidrug resistance in Italy","volume":"67","author":"Giufre","year":"2012","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0090","first-page":"1853","article-title":"Highly pathogenic strains of Escherichia coli revealed by the distinct electrophoretic patterns of carboxylesterase B","volume":"132","author":"Goullet","year":"1986","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0095","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1089\/mdr.2013.0157","article-title":"Characterization of third-generation cephalosporin-resistant Escherichia coli from bloodstream infections in Denmark","volume":"20","author":"Hansen","year":"2014","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0100","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.1093\/jac\/dkt219","article-title":"Within-farm dynamics of ESBL\/AmpC-producing Escherichia coli in veal calves: a longitudinal approach","volume":"68","author":"Hordijk","year":"2013","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0105","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1086\/315217","article-title":"Extended virulence genotypes of Escherichia coli. strains from patients with urosepsis in relation to phylogeny and host compromise","volume":"181","author":"Johnson","year":"2000","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0110","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1128\/JCM.03502-13","article-title":"Rapid and specific detection, molecular epidemiology, and experimental virulence of the O16 subgroup within Escherichia coli sequence type 131","volume":"52","author":"Johnson","year":"2014","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0115","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1128\/JCM.06094-11","article-title":"Multilocus sequence typing of total-genome-sequenced bacteria","volume":"50","author":"Larsen","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0120","doi-asserted-by":"crossref","first-page":"e74323","DOI":"10.1371\/journal.pone.0074323","article-title":"Risk factors associated with the community-acquired colonization of extended-spectrum beta-lactamase (ESBL) positive Escherichia coli. an exploratory case\u2013control study","volume":"8","author":"Leistner","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.vetmic.2015.11.028_bib0125","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1093\/jac\/dki239","article-title":"CTX-M: changing the face of ESBLs in the UK","volume":"56","author":"Livermore","year":"2005","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0130","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.ijantimicag.2011.01.001","article-title":"Characterisation of clinical and food animal Escherichia coli isolates producing CTX-M-15 extended-spectrum beta-lactamase belonging to ST410 phylogroup A","volume":"37","author":"Lopez-Cerero","year":"2011","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.vetmic.2015.11.028_bib0135","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1128\/CMR.00116-14","article-title":"The role of epidemic resistance plasmids and international high-risk clones in the spread of multidrug-resistant Enterobacteriaceae","volume":"28","author":"Mathers","year":"2015","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0140","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1089\/mdr.2010.0132","article-title":"The CTX-M conundrum: dissemination of plasmids and E. coli clones","volume":"17","author":"Naseer","year":"2011","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0145","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.ijantimicag.2009.03.006","article-title":"Extended-spectrum beta-lactamase-producing Escherichia coli in Spain belong to a large variety of multilocus sequence typing types, including ST10 complex\/A, ST23 complex\/A and ST131\/B2","volume":"34","author":"Oteo","year":"2009","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.vetmic.2015.11.028_bib0150","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1111\/j.1469-0691.2010.03440.x","article-title":"Molecular characteristics of extended-spectrum beta-lactamase-producing Escherichia coli from Rio de Janeiro, Brazil","volume":"17","author":"Peirano","year":"2011","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0155","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1128\/JCM.06025-11","article-title":"Molecular epidemiology over an 11-year period (2000 to 2010) of extended-spectrum beta-lactamase-producing Escherichia coli causing bacteremia in a centralized Canadian region","volume":"50","author":"Peirano","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0160","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.ijmm.2010.04.005","article-title":"Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens","volume":"300","author":"Pfeifer","year":"2010","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0165","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.ijantimicag.2014.02.019","article-title":"Chromosomal location of blaCTX-M genes in clinical isolates of Escherichia coli from Germany, The Netherlands and the UK","volume":"43","author":"Rodriguez","year":"2014","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.vetmic.2015.11.028_bib0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jac\/dkq415","article-title":"Escherichia coli O25b-ST131: a pandemic, multiresistant, community-associated strain","volume":"66","author":"Rogers","year":"2011","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0175","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1093\/jac\/dkt123","article-title":"Analysis of extended-spectrum-beta-lactamase-producing Escherichia coli isolates collected in the GERM-Vet monitoring programme","volume":"68","author":"Schink","year":"2013","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0180","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1089\/mdr.2009.0132","article-title":"Characterization of extended-spectrum beta-lactamases produced by Escherichia coli isolated from hospitalized and nonhospitalized patients: emergence of CTX-M-15-producing strains causing urinary tract infections","volume":"16","author":"Smet","year":"2010","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0185","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.ijmm.2014.07.015","article-title":"Subgrouping of ESBL-producing Escherichia coli from animal and human sources: an approach to quantify the distribution of ESBL types between different reservoirs","volume":"304","author":"Valentin","year":"2014","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0190","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1128\/AAC.01993-13","article-title":"Extended-spectrum-beta-lactamase-producing Escherichia coli as intestinal colonizers in the German community","volume":"58","author":"Valenza","year":"2014","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.vetmic.2015.11.028_bib0195","doi-asserted-by":"crossref","first-page":"e52102","DOI":"10.1371\/journal.pone.0052102","article-title":"Population distribution of Beta-lactamase conferring resistance to third-generation cephalosporins in human clinical Enterobacteriaceae in the Netherlands","volume":"7","author":"Voets","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.vetmic.2015.11.028_bib0200","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1111\/j.1365-2958.2006.05172.x","article-title":"Sex and virulence in Escherichia coli: an evolutionary perspective","volume":"60","author":"Wirth","year":"2006","journal-title":"Mol. Microbiol."}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113515300973?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113515300973?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T09:20:31Z","timestamp":1537176031000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113515300973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":40,"alternative-id":["S0378113515300973"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2015.11.028","relation":{},"ISSN":["0378-1135"],"issn-type":[{"value":"0378-1135","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular characterisation of extended-spectrum \u03b2-lactamase (ESBL)-producing Escherichia coli isolates from hospital and ambulatory patients in Germany","name":"articletitle","label":"Article Title"},{"value":"Veterinary Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetmic.2015.11.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}