{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:13:25Z","timestamp":1790673205836,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1016\/j.vetmic.2017.04.030","type":"journal-article","created":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T11:31:06Z","timestamp":1493638266000},"page":"26-33","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Streptococcus suis serotype 9 strain GZ0565 contains a type VII secretion system putative substrate EsxA that contributes to bacterial virulence and a vanZ- like gene that confers resistance to teicoplanin and dalbavancin in Streptococcus agalactiae"],"prefix":"10.1016","volume":"205","author":[{"given":"Liying","family":"Lai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanyu","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shouming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wancen","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengping","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huochun","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjie","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongfu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetmic.2017.04.030_bib0005","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1038\/nrmicro1773","article-title":"Type VII secretion-mycobacteria show the way","volume":"5","author":"Abdallah","year":"2007","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0010","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1111\/mmi.12395","article-title":"Secretion of atypical protein substrates by the ESAT-6 secretion system of Staphylococcus aureus","volume":"90","author":"Anderson","year":"2013","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0015","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0378-1119(94)00851-I","article-title":"The vanZ gene of Tn1546 from Enterococcus faecium BM4147 confers resistance to teicoplanin","volume":"154","author":"Arthur","year":"1995","journal-title":"Gene"},{"key":"10.1016\/j.vetmic.2017.04.030_bib0020","doi-asserted-by":"crossref","DOI":"10.1111\/cmi.12726","article-title":"ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis","author":"Augenstreich","year":"2017","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0025","doi-asserted-by":"crossref","first-page":"3691","DOI":"10.1099\/mic.0.27142-0","article-title":"A new Bacillus cereus DNA-binding protein HlyIIR, negatively regulates expression of B. cereus haemolysin II","volume":"150","author":"Budarina","year":"2004","journal-title":"Microbiology"},{"key":"10.1016\/j.vetmic.2017.04.030_bib0030","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1073\/pnas.0405620102","article-title":"EsxA and EsxB are secreted by an ESAT-6-like system that is required for the pathogenesis of Staphylococcus aureus infections","volume":"102","author":"Burts","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0035","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1111\/j.1365-2958.2008.06324.x","article-title":"EsaC substrate for the ESAT-6 secretion pathway and its role in persistent infections of Staphylococcus aureus","volume":"69","author":"Burts","year":"2008","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0040","doi-asserted-by":"crossref","first-page":"e315","DOI":"10.1371\/journal.pone.0000315","article-title":"A glimpse of streptococcal toxic shock syndrome from comparative genomics of S suis 2 Chinese isolates","volume":"2","author":"Chen","year":"2007","journal-title":"PLoS One"},{"key":"10.1016\/j.vetmic.2017.04.030_bib0045","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s12038-016-9599-8","article-title":"In silico dissection of Type VII Secretion System components across bacteria: new directions towards functional characterization","volume":"41","author":"Das","year":"2016","journal-title":"J. Biosci."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0050","doi-asserted-by":"crossref","first-page":"3866","DOI":"10.1074\/jbc.M505556200","article-title":"A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis","volume":"281","author":"Deb","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0055","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens5030046","article-title":"Simultaneous quantification and differentiation of streptococcus suis serotypes 2 and 9 by quantitative real-Time PCR, evaluated in tonsillar and nasal samples of pigs","volume":"5","author":"Dekker","year":"2016","journal-title":"Pathogens"},{"key":"10.1016\/j.vetmic.2017.04.030_bib0060","doi-asserted-by":"crossref","first-page":"371","DOI":"10.2217\/fmb.10.2","article-title":"Streptococcus suis: a new emerging or an old neglected zoonotic pathogen?","volume":"5","author":"Gottschalk","year":"2010","journal-title":"Future Microbiol."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0065","doi-asserted-by":"crossref","first-page":"E5498","DOI":"10.1073\/pnas.1412070111","article-title":"Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system","volume":"111","author":"Habazettl","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0070","doi-asserted-by":"crossref","first-page":"e6072","DOI":"10.1371\/journal.pone.0006072","article-title":"Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis","volume":"4","author":"Holden","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.vetmic.2017.04.030_bib0075","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3389\/fmicb.2016.00055","article-title":"Comparative genomic analysis of the ICESa2603 family ICEs and spread of erm(B)- and tet(O)-carrying transferable 89K-Subtype ICEs in swine and bovine isolates in China","volume":"7","author":"Huang","year":"2016","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmii.2015.06.011","article-title":"Emergence of Streptococcus suis serotype 9 infection in humans","author":"Kerdsin","year":"2015","journal-title":"J. Microbiol. Immunol. Infect."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0085","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1101\/gr.092759.109","article-title":"Circos: an information aesthetic for comparative genomics","volume":"19","author":"Krzywinski","year":"2009","journal-title":"Genome Res."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0090","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1099\/ijsem.0.000760","article-title":"OrthoANI: an improved algorithm and software for calculating average nucleotide identity","volume":"66","author":"Lee","year":"2016","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0095","doi-asserted-by":"crossref","first-page":"6653","DOI":"10.1128\/JB.01788-12","article-title":"Complete genome sequence of Streptococcus agalactiae GD201008-001, isolated in China from tilapia with meningoencephalitis","volume":"194","author":"Liu","year":"2012","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0100","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/nrmicro3399","article-title":"What is a resistance gene? Ranking risk in resistomes","volume":"13","author":"Martinez","year":"2015","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0105","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1128\/AAC.05869-11","article-title":"A novel membrane protein, VanJ, conferring resistance to teicoplanin","volume":"56","author":"Novotna","year":"2012","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0110","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1128\/MMBR.69.2.326-356.2005","article-title":"The TetR family of transcriptional repressors","volume":"69","author":"Ramos","year":"2005","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0115","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.tube.2014.02.001","article-title":"Increased virulence of Mycobacterium tuberculosis H37Rv overexpressing LipY in a murine model","volume":"94","author":"Singh","year":"2014","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.vetmic.2017.04.030_bib0120","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s40121-015-0077-7","article-title":"Dalbavancin: a novel lipoglycopeptide antibiotic with extended activity against gram-positive infections","volume":"4","author":"Smith","year":"2015","journal-title":"Infect. Dis. Ther."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0125","doi-asserted-by":"crossref","first-page":"e11970","DOI":"10.1371\/journal.pone.0011970","article-title":"sRNAscanner: a computational tool for intergenic small RNA detection in bacterial genomes","volume":"5","author":"Sridhar","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.vetmic.2017.04.030_bib0130","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1126\/science.1179663","article-title":"Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium","volume":"327","author":"Volkman","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.vetmic.2017.04.030_bib0135","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/j.1574-6968.2010.02189.x","article-title":"Reduced virulence is an important characteristic of biofilm infection of Streptococcus suis","volume":"316","author":"Wang","year":"2011","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0140","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.micpath.2008.04.009","article-title":"Comparative proteome analysis of secreted proteins of Streptococcus suis serotype 9 isolates from diseased and healthy pigs","volume":"45","author":"Wu","year":"2008","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0145","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.gene.2013.11.044","article-title":"Comparative genomic analysis shows that Streptococcus suis meningitis isolate SC070731 contains a unique 105K genomic island","volume":"535","author":"Wu","year":"2014","journal-title":"Gene"},{"key":"10.1016\/j.vetmic.2017.04.030_bib0150","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1261\/rna.041822.113","article-title":"The Streptococcus suis transcriptional landscape reveals adaptation mechanisms in pig blood and cerebrospinal fluid","volume":"20","author":"Wu","year":"2014","journal-title":"RNA"},{"key":"10.1016\/j.vetmic.2017.04.030_bib0155","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.3201\/eid1708.060232","article-title":"Streptococcus suis sequence type 7 outbreak, sichuan, China","volume":"12","author":"Ye","year":"2006","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0160","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1086\/594370","article-title":"Clinical, experimental, and genomic differences between intermediately pathogenic, highly pathogenic, and epidemic Streptococcus suis","volume":"199","author":"Ye","year":"2009","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0165","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a026989","article-title":"Approved glycopeptide antibacterial drugs: mechanism of action and resistance","volume":"6","author":"Zeng","year":"2016","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0170","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.vetmic.2009.06.034","article-title":"Identification and characterization of IgA1 protease from Streptococcus suis","volume":"140","author":"Zhang","year":"2010","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2017.04.030_bib0175","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.micpath.2011.08.002","article-title":"The novel virulence-related gene stp of Streptococcus suis serotype 9 strain contributes to a significant reduction in mouse mortality","volume":"51","author":"Zhu","year":"2011","journal-title":"Microb. Pathog."}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113517301281?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113517301281?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,2]],"date-time":"2018-09-02T02:28:29Z","timestamp":1535855309000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113517301281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":35,"alternative-id":["S0378113517301281"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2017.04.030","relation":{},"ISSN":["0378-1135"],"issn-type":[{"value":"0378-1135","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Streptococcus suis serotype 9 strain GZ0565 contains a type VII secretion system putative substrate EsxA that contributes to bacterial virulence and a vanZ-like gene that confers resistance to teicoplanin and dalbavancin in Streptococcus agalactiae","name":"articletitle","label":"Article Title"},{"value":"Veterinary Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetmic.2017.04.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}