{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:01:24Z","timestamp":1759968084835,"version":"build-2065373602"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100009881","name":"Regione Liguria","doi-asserted-by":"publisher","award":["12ALA"],"award-info":[{"award-number":["12ALA"]}],"id":[{"id":"10.13039\/501100009881","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.vetmic.2020.108596","type":"journal-article","created":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T14:35:54Z","timestamp":1579876554000},"page":"108596","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Yersinia enterocolitica-specific modulation of innate immune responses in jejunal epithelial cells"],"prefix":"10.1016","volume":"242","author":[{"given":"Elisabetta","family":"Razzuoli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Vencia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Modesto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Franzoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia Dei","family":"Giudici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erica","family":"Parisi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Amadori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetmic.2020.108596_bib0005","doi-asserted-by":"crossref","first-page":"397","DOI":"10.5604\/12321966.1167700","article-title":"Yersiniosis - a zoonotic foodborne disease of relevance to public health","volume":"22","author":"Bancerz-Kisiel","year":"2015","journal-title":"Ann. Agric. Environ. Med."},{"key":"10.1016\/j.vetmic.2020.108596_bib0010","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.vetmic.2011.10.017","article-title":"Porcine IPEC-J2 intestinal epithelial cells in microbiological investigations","volume":"156","author":"Brosnahan","year":"2012","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0015","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1099\/jmm.0.056077-0","article-title":"Interaction of Yersinia enterocolitica biovar 1A with cultured cells in vitro does not reflect the two previously identified clonal groups","volume":"62","author":"Dhar","year":"2013","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0020","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1099\/0022-1317-49-10-897","article-title":"Infection of human enterocyte-like cells with rotavirus enhances invasiveness of Yersinia enterocolitica and Y. pseudotuberculosis","volume":"49","author":"Di Biase","year":"2000","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0025","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1080\/03009740600906651","article-title":"Yersinia-triggered arthritis in IL-12p40-deficient mice: relevant antigens and local expression of Toll-like receptor mRNA","volume":"36","author":"Di Genaro","year":"2007","journal-title":"Scand. J. Rheumatol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0030","first-page":"491","article-title":"Macrophage cytokines: involvement in immunity and infectious diseases","volume":"5","author":"Duque","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0035","doi-asserted-by":"crossref","DOI":"10.2903\/j.efsa.2018.5500","article-title":"The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2017","author":"European Food Safety Authority and European Centre for Disease Prevention and Control (EFSA and ECDC)","year":"2018","journal-title":"Efsa J."},{"key":"10.1016\/j.vetmic.2020.108596_bib0040","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.eimc.2011.07.017","article-title":"Yersinia enterocolitica: pathogenesis, virulence and antimicrobial resistance","volume":"30","author":"F\u00e0brega","year":"2012","journal-title":"Enferm. Infecc. Microbiol. Clin."},{"key":"10.1016\/j.vetmic.2020.108596_bib0045","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.vetmic.2018.02.021","article-title":"Interaction of porcine monocyte-derived dendritic cells with African swine fever viruses of diverse virulence","volume":"216","author":"Franzoni","year":"2018","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0050","first-page":"51","article-title":"Evaluation of the usefulness of selected virulence markers for identification of virulent Yersinia enterocolitica strains. III. Chromosome markers of virulence","volume":"52","author":"Gierczy\u0144ski","year":"2000","journal-title":"Med. Do\u015bw. Mikrobiol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0055","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1128\/IAI.68.5.2484-2492.2000","volume":"68","author":"Kampik","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetmic.2020.108596_bib0060","doi-asserted-by":"crossref","first-page":"228","DOI":"10.4110\/in.2017.17.4.228","article-title":"Yersinia enterocolitica exploits signal crosstalk between complement 5a receptor and toll-like receptor 1\/2 and 4 to avoid the bacterial clearance in m cells","volume":"4","author":"Kim","year":"2017","journal-title":"Immune Netw."},{"key":"10.1016\/j.vetmic.2020.108596_bib0065","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.vetimm.2009.04.006","article-title":"Gene expression study of two widely used pig intestinal epithelial cell lines: IPEC-J2 and IPI-2I","volume":"131","author":"Mariani","year":"2009","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0193573","article-title":"IL-12\/23p40 overproduction by dendritic cells leads to an increased Th1 and Th17 polarization in a model of Yersinia enterocolitica-induced reactive arthritis in TNFRp55-\/- mice","author":"Mayordomo","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.vetmic.2020.108596_bib0075","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.jdermsci.2005.07.009","article-title":"Protective roles of the skin against infection: implication of naturally occurring human antimicrobial agents beta-defensins, cathelicidin LL-37 and lysozyme","volume":"40","author":"Niyonsaba","year":"2005","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.vetmic.2020.108596_bib0080","first-page":"11","article-title":"Antimicrobial peptide resistance mechanisms of human bacterial pathogens","volume":"8","author":"Nizet","year":"2006","journal-title":"Curr. Issues Mol. Biol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0085","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.fm.2017.03.004","article-title":"Evaluation of virulence genes in Yersinia enterocolitica strains using SYBR Green real-time PCR","volume":"65","author":"Peruzy","year":"2017","journal-title":"Food Microbiol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0090","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1439-0450.2006.00969.x","article-title":"Analysis of the presence of ail, ystA and ystB genes in Yersinia enterocolitica strains isolated from aborting sows and aborted fetuses","volume":"5","author":"Platt-Samoraj","year":"2006","journal-title":"J. Vet. Med. B Infect. Dis. Vet. Public Health"},{"key":"10.1016\/j.vetmic.2020.108596_bib0095","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/j.1365-3083.2011.02586.x","article-title":"Reverse transcription real-time PCR for detection of porcine interferon \u03b1 and \u03b2 genes","volume":"74","author":"Razzuoli","year":"2011","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0100","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1089\/jir.2012.0127","article-title":"IPEC-J2 cells as reporter system of the anti-inflammatory control actions of interferon-alpha","volume":"33","author":"Razzuoli","year":"2013","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.vetmic.2020.108596_bib0105","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.vetmic.2017.07.002","article-title":"Salmonella serovar-specific interaction with jejunal epithelial cells","volume":"207","author":"Razzuoli","year":"2017","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0110","doi-asserted-by":"crossref","first-page":"3173","DOI":"10.1128\/JB.00308-12","article-title":"Molecular basis of Yersinia enterocolitica temperature-dependent resistance to antimicrobial peptides","volume":"194","author":"Rein\u00e9s","year":"2012","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0115","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.dci.2008.05.006","article-title":"Porcine host defense peptides: expanding repertoire and functions","volume":"33","author":"Sang","year":"2009","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0120","first-page":"347","article-title":"The porcine immune system differences compared to man and mouse and possible consequences for infections by Salmonella serovars","volume":"120","author":"Scharek","year":"2007","journal-title":"Berl. Munch. Tierarztl. Wochenschr."},{"key":"10.1016\/j.vetmic.2020.108596_bib0125","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s00418-005-0067-z","article-title":"Characterization of a porcine intestinal epithelial cell line for in vitro studies of microbial pathogenesis in swine","volume":"125","author":"Schierack","year":"2006","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0130","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1128\/iai.64.6.2106-2113.1996","article-title":"Differential secretion of interleukin-8 by human epithelial cell lines upon entry of virulent or nonvirulent Yersinia enterocolitica","volume":"64","author":"Schulte","year":"1996","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetmic.2020.108596_bib0135","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s004300050074","article-title":"Wortmannin blocks Yersinia invasin-triggered internalization, but not interleukin-8 production by epithelial cells","volume":"187","author":"Schulte","year":"1998","journal-title":"Med. Microbiol. Immunol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0140","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/mi.2013.5","article-title":"TLR1-induced chemokine production is critical for mucosal immunity against Yersinia enterocolitica","volume":"6","author":"Sugiura","year":"2013","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.vetmic.2020.108596_bib0145","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1007\/s00296-017-3816-0","article-title":"Yersinia enterocolitica biotype 1A: a possible new trigger of reactive arthritis","volume":"37","author":"Tuompo","year":"2017","journal-title":"Rheumatol. Int."},{"issue":"Oct;40(10)","key":"10.1016\/j.vetmic.2020.108596_bib0150","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1002\/art.1780401010","article-title":"Crucial role of interleukin-10\/interleukin-12 balance in the regulation of the type 2 T helper cytokine response in reactive arthritis","volume":"1997","author":"Yin","year":"1997","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.vetmic.2020.108596_bib0155","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1089\/jir.2015.0076","article-title":"Differential biological activities of swine Interferon-\u03b1 subtypes","volume":"35","author":"Zanotti","year":"2015","journal-title":"J. Interferon Cytokine Res."}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113519313094?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113519313094?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T23:06:32Z","timestamp":1759878392000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113519313094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":31,"alternative-id":["S0378113519313094"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2020.108596","relation":{},"ISSN":["0378-1135"],"issn-type":[{"type":"print","value":"0378-1135"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Yersinia enterocolitica-specific modulation of innate immune responses in jejunal epithelial cells","name":"articletitle","label":"Article Title"},{"value":"Veterinary Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetmic.2020.108596","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"108596"}}