{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:03:33Z","timestamp":1759968213319,"version":"build-2065373602"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.vetmic.2021.109157","type":"journal-article","created":{"date-parts":[[2021,6,18]],"date-time":"2021-06-18T10:58:31Z","timestamp":1624013911000},"page":"109157","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["OmpC, a novel factor H-binding surface protein, is dispensable for the adherence and virulence of Salmonella enterica serovar Typhimurium"],"prefix":"10.1016","volume":"259","author":[{"given":"Quan","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xia","family":"Fei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanzhao","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiwei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dianfeng","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaobo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shifeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huoying","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetmic.2021.109157_bib0005","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/520179","article-title":"Salmonella enterica: survival, colonization, and virulence differences among serovars","volume":"2015","author":"Andino","year":"2015","journal-title":"Sci. World J."},{"key":"10.1016\/j.vetmic.2021.109157_bib0010","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1021\/acsinfecdis.0c00102","article-title":"Kanamycin uptake into Escherichia coli is facilitated by OmpF and OmpC porin channels located in the outer membrane","volume":"6","author":"Bafna","year":"2020","journal-title":"ACS Infect. Dis."},{"key":"10.1016\/j.vetmic.2021.109157_bib0015","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1073\/pnas.1521142113","article-title":"Expression of factor H binding protein in meningococcal strains can vary at least 15-fold and is genetically determined","volume":"113","author":"Biagini","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.vetmic.2021.109157_bib0020","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1099\/jmm.0.47848-0","article-title":"Growth-phase regulation of lipopolysaccharide O-antigen chain length influences serum resistance in serovars of Salmonella","volume":"57","author":"Bravo","year":"2008","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.vetmic.2021.109157_bib0025","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1128\/IAI.00693-08","article-title":"Salmonella enterica serovar typhimurium strains with regulated delayed attenuation in vivo","volume":"77","author":"Curtiss","year":"2009","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetmic.2021.109157_bib0030","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0378-1119(97)00619-7","article-title":"Improved allelic exchange vectors and their use to analyze 987\u2009P fimbria gene expression","volume":"207","author":"Edwards","year":"1998","journal-title":"Gene"},{"key":"10.1016\/j.vetmic.2021.109157_bib0035","doi-asserted-by":"crossref","first-page":"5913","DOI":"10.4049\/jimmunol.1303449","article-title":"Identification of a Haemophilus influenzae factor H-Binding lipoprotein involved in serum resistance","volume":"192","author":"Fleury","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.vetmic.2021.109157_bib0040","first-page":"150","article-title":"Identification of novel fibronectin-binding proteins by 2D-far Western blot in atypical enteropathogenic Escherichia coli serotype O55:H7","author":"Guo","year":"2021","journal-title":"Microb Pathogenesis"},{"key":"10.1016\/j.vetmic.2021.109157_bib0045","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/0923-2508(90)90119-B","article-title":"Control of colonization by virulent Salmonella typhimurium by oral immunization of chickens with avirulent delta cya delta crp S. Typhimurium","volume":"141","author":"Hassan","year":"1990","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.vetmic.2021.109157_bib0050","doi-asserted-by":"crossref","first-page":"5183","DOI":"10.1128\/iai.62.11.5183-5186.1994","article-title":"Specificity of the complement resistance and cell association phenotypes encoded by the outer membrane protein genes rck from Salmonella typhimurium and ail from Yersinia enterocolitica","volume":"62","author":"Heffernan","year":"1994","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetmic.2021.109157_bib0055","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.micpath.2017.02.033","article-title":"Functional role of ompF and ompC porins in pathogenesis of avian pathogenic Escherichia coli","volume":"107","author":"Hejair","year":"2017","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.vetmic.2021.109157_bib0060","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.4049\/jimmunol.1001244","article-title":"Human complement factor H binds to outer membrane protein Rck of Salmonella","volume":"185","author":"Ho","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.vetmic.2021.109157_bib0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027546","article-title":"Functional recruitment of human complement inhibitor C4B-binding protein to outer membrane protein Rck of Salmonella","volume":"6","author":"Ho","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.vetmic.2021.109157_bib0070","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1084\/jem.155.3.797","article-title":"Studies on the mechanism of bacterial resistance to complement-mediated killing. I. Terminal complement components are deposited and released from Salmonella minnesota S218 without causing bacterial death","volume":"155","author":"Joiner","year":"1982","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.vetmic.2021.109157_bib0075","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1002\/1873-3468.13771","article-title":"Complement evasion mechanisms of the systemic pathogens Yersiniae and Salmonellae","volume":"594","author":"Krukonis","year":"2020","journal-title":"FEBS Lett."},{"key":"10.1016\/j.vetmic.2021.109157_bib0080","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.vetmic.2017.07.010","article-title":"Fibronectin-\/fibrinogen-binding protein (FBPS) is not a critical virulence factor for the Streptococcus suis serotype 2 strain ZY05719","volume":"208","author":"Li","year":"2017","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2021.109157_bib0085","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.micres.2016.11.011","article-title":"Factor H specifically capture novel Factor H-binding proteins of Streptococcus suis and contribute to the virulence of the bacteria","volume":"196","author":"Li","year":"2017","journal-title":"Microbiol. Res. (Pavia)"},{"key":"10.1016\/j.vetmic.2021.109157_bib0090","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s13568-019-0936-9","article-title":"Serotype distribution, antimicrobial susceptibility, antimicrobial resistance genes and virulence genes of Salmonella isolated from a pig slaughterhouse in Yangzhou, China","volume":"9","author":"Li","year":"2019","journal-title":"AMB Express"},{"key":"10.1016\/j.vetmic.2021.109157_bib0095","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/s13568-020-01042-2","article-title":"Identification of novel pig and human immunoglobulin G-binding proteins and characterization of the binding regions of enolase from Streptococcus suis serotype 2","volume":"10","author":"Li","year":"2020","journal-title":"AMB Express"},{"key":"10.1016\/j.vetmic.2021.109157_bib0100","doi-asserted-by":"crossref","first-page":"6904","DOI":"10.1016\/j.vaccine.2020.08.062","article-title":"Live attenuated Salmonella enterica serovar Choleraesuis vector delivering a conserved surface protein enolase induces high and broad protection against Streptococcus suis serotypes 2, 7, and 9 in mice","volume":"38","author":"Li","year":"2020","journal-title":"Vaccine"},{"key":"10.1016\/j.vetmic.2021.109157_bib0105","doi-asserted-by":"crossref","first-page":"16109","DOI":"10.1038\/s41598-018-33972-0","article-title":"An integrated impedance biosensor platform for detection of pathogens in poultry products","volume":"8","author":"Liu","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.vetmic.2021.109157_bib0110","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1139\/w99-053","article-title":"The porin OmpC of Salmonella typhimurium mediates adherence to macrophages","volume":"45","author":"Negm","year":"1999","journal-title":"Can. J. Microbiol."},{"key":"10.1016\/j.vetmic.2021.109157_bib0115","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1128\/MMBR.67.4.593-656.2003","article-title":"Molecular basis of bacterial outer membrane permeability revisited","volume":"67","author":"Nikaido","year":"2003","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.vetmic.2021.109157_bib0120","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1016\/j.molimm.2005.09.012","article-title":"Localization of the third heparin-binding site in the human complement regulator factor H1","volume":"43","author":"Ormsby","year":"2006","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.vetmic.2021.109157_bib0125","doi-asserted-by":"crossref","first-page":"4742","DOI":"10.4049\/jimmunol.164.9.4742","article-title":"Molecular mechanisms of target recognition in an innate immune system: interactions among factor H, C3b, and target in the alternative pathway of human complement","volume":"164","author":"Pangburn","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.vetmic.2021.109157_bib0130","doi-asserted-by":"crossref","first-page":"230","DOI":"10.3389\/fimmu.2017.00230","article-title":"Salmonella typhi porins OmpC and OmpF are potent adjuvants for T-Dependent and T-Independent antigens","volume":"8","author":"Perez-Toledo","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.vetmic.2021.109157_bib0135","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1128\/IAI.06294-11","article-title":"Fhb, a novel factor H-binding surface protein, contributes to the antiphagocytic ability and virulence of Streptococcus suis","volume":"80","author":"Pian","year":"2012","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetmic.2021.109157_bib0140","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.biologicals.2013.01.003","article-title":"Evaluation of recombinant outer membrane protein based vaccine against Salmonella typhimurium in birds","volume":"41","author":"Prejit","year":"2013","journal-title":"Biologicals"},{"key":"10.1016\/j.vetmic.2021.109157_bib0145","doi-asserted-by":"crossref","first-page":"4082","DOI":"10.1128\/IAI.00474-07","article-title":"Factor H binding to PspC of Streptococcus pneumoniae increases adherence to human cell lines in vitro and enhances invasion of mouse lungs in vivo","volume":"75","author":"Quin","year":"2007","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetmic.2021.109157_bib0150","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1016\/j.febslet.2007.03.049","article-title":"The surface protease PgtE of Salmonella enterica affects complement activity by proteolytically cleaving C3b, C4b and C5","volume":"581","author":"Ramu","year":"2007","journal-title":"FEBS Lett."},{"key":"10.1016\/j.vetmic.2021.109157_bib0155","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3389\/fmicb.2015.00063","article-title":"The outer membrane protease PgtE of Salmonella enterica interferes with the alternative complement pathway by cleaving factors B and H","volume":"6","author":"Riva","year":"2015","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.vetmic.2021.109157_bib0160","doi-asserted-by":"crossref","first-page":"429","DOI":"10.2307\/1592640","article-title":"Construction and evaluation of a delta cya delta crp Salmonella typhimurium strain expressing avian pathogenic Escherichia coli O78 LPS as a vaccine to prevent airsacculitis in chickens","volume":"43","author":"Roland","year":"1999","journal-title":"Avian Dis."},{"key":"10.1016\/j.vetmic.2021.109157_bib0165","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/cr.2010.45","article-title":"Rck of Salmonella enterica, subspecies enterica serovar enteritidis, mediates zipper-like internalization","volume":"20","author":"Rosselin","year":"2010","journal-title":"Cell Res."},{"key":"10.1016\/j.vetmic.2021.109157_bib0170","doi-asserted-by":"crossref","first-page":"4481","DOI":"10.1038\/s41598-018-22670-6","article-title":"Comparative roles of clpA and clpB in the survival of S. Typhimurium under stress and virulence in poultry","volume":"8","author":"Sangpuii","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.vetmic.2021.109157_bib0175","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1365-2567.2005.02263.x","article-title":"Salmonella porins induce a sustained, lifelong specific bactericidal antibody memory response","volume":"117","author":"Secundino","year":"2006","journal-title":"Immunology"},{"key":"10.1016\/j.vetmic.2021.109157_bib0180","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004310","article-title":"Trichinella spiralis paramyosin binds human complement C1q and inhibits classical complement activation","volume":"9","author":"Sun","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.vetmic.2021.109157_bib0185","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.biochi.2006.05.010","article-title":"Functional assay of Salmonella typhi OmpC using reconstituted large unilamellar vesicles: a general method for characterization of outer membrane proteins","volume":"88","author":"Sundara Baalaji","year":"2006","journal-title":"Biochimie"},{"key":"10.1016\/j.vetmic.2021.109157_bib0190","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0167-7012(99)00052-4","article-title":"Automated detection of Salmonella spp. In foods","volume":"37","author":"Tan","year":"1999","journal-title":"J. Microbiol. Methods"},{"key":"10.1016\/j.vetmic.2021.109157_bib0195","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1080\/19490976.2019.1697593","article-title":"The YrbE phospholipid transporter of Salmonella enterica serovar Typhi regulates the expression of flagellin and influences motility, adhesion and induction of epithelial inflammatory responses","volume":"11","author":"Verma","year":"2020","journal-title":"Gut Microbes"},{"key":"10.1016\/j.vetmic.2021.109157_bib0200","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1056\/NEJM200104053441406","article-title":"Complement. First of two parts","volume":"344","author":"Walport","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.vetmic.2021.109157_bib0205","article-title":"Bacillus anthracis spore surface protein BclA mediates complement factor H binding to spores and promotes spore persistence","volume":"12","author":"Wang","year":"2016","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.vetmic.2021.109157_bib0210","doi-asserted-by":"crossref","first-page":"4180","DOI":"10.1096\/fj.201600701R","article-title":"Identification of the epidermal growth factor receptor as the receptor for Salmonella Rck-dependent invasion","volume":"30","author":"Wiedemann","year":"2016","journal-title":"FASEB J."},{"key":"10.1016\/j.vetmic.2021.109157_bib0215","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1080\/21505594.2020.1806664","article-title":"Mycoplasma hyopneumoniae evades complement activation by binding to factor H via elongation factor thermo unstable (EF-Tu)","volume":"11","author":"Yu","year":"2020","journal-title":"Virulence"},{"key":"10.1016\/j.vetmic.2021.109157_bib0220","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/j.1574-695X.2012.00947.x","article-title":"Immunoproteomic identification of 11 novel immunoreactive proteins of Riemerella anatipestifer serotype 2","volume":"65","author":"Zhai","year":"2012","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"10.1016\/j.vetmic.2021.109157_bib0225","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1038\/nri2620","article-title":"Complement regulators and inhibitory proteins","volume":"9","author":"Zipfel","year":"2009","journal-title":"Nat. Rev. Immunol."}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113521001802?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113521001802?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T23:15:55Z","timestamp":1759878955000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113521001802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":45,"alternative-id":["S0378113521001802"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2021.109157","relation":{},"ISSN":["0378-1135"],"issn-type":[{"type":"print","value":"0378-1135"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"OmpC, a novel factor H-binding surface protein, is dispensable for the adherence and virulence of Salmonella enterica serovar Typhimurium","name":"articletitle","label":"Article Title"},{"value":"Veterinary Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetmic.2021.109157","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"109157"}}