{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:21:10Z","timestamp":1792639270861,"version":"4.5.0"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31902243"],"award-info":[{"award-number":["31902243"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013058","name":"Jiangsu Provincial Key Research and Development Program","doi-asserted-by":"publisher","award":["BE2020336"],"award-info":[{"award-number":["BE2020336"]}],"id":[{"id":"10.13039\/501100013058","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.vetmic.2022.109450","type":"journal-article","created":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T21:10:35Z","timestamp":1651698635000},"page":"109450","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Effect of multiplicity of infection on the evasion of neutrophil killing by Streptococcus agalactiae isolated from clinical mastitis bovine"],"prefix":"10.1016","volume":"270","author":[{"given":"Fang","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shifang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingxu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinqiu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bihua","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenzhu","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjie","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetmic.2022.109450_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2019.110580","article-title":"The effects of acute BPA exposure on skeletal muscle mitochondrial function and glucose metabolism","volume":"499","author":"Ahmed","year":"2020","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.vetmic.2022.109450_bib2","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/ni.2987","article-title":"Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens","volume":"15","author":"Branzk","year":"2014","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.vetmic.2022.109450_bib3","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1126\/science.1092385","article-title":"Neutrophil extracellular traps kill bacteria","volume":"303","author":"Brinkmann","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.vetmic.2022.109450_bib4","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.cub.2005.12.039","article-title":"DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps","volume":"16","author":"Buchanan","year":"2006","journal-title":"Current Bio.: CB"},{"key":"10.1016\/j.vetmic.2022.109450_bib5","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.4049\/jimmunol.1202811","article-title":"Infection and cellular defense dynamics in a novel 17beta-estradiol murine model of chronic human group B Streptococcus genital tract colonization reveal a role for hemolysin in persistence and neutrophil accumulation","volume":"192","author":"Carey","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.vetmic.2022.109450_bib6","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1084\/jem.20090691","article-title":"Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5","volume":"206","author":"Carlin","year":"2009","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.vetmic.2022.109450_bib7","doi-asserted-by":"crossref","first-page":"e00230","DOI":"10.1128\/IAI.00230-20","article-title":"Cathelicidins mitigate staphylococcus aureus mastitis and reduce bacterial invasion in murine mammary epithelium","volume":"88","author":"Cavalcante","year":"2020","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetmic.2022.109450_bib8","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1111\/mmi.12295","article-title":"Nuclease A (Gbs0661), an extracellular nuclease of Streptococcus agalactiae, attacks the neutrophil extracellular traps and is needed for full virulence","volume":"89","author":"Derre-Bobillot","year":"2013","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.vetmic.2022.109450_bib9","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.ijantimicag.2017.08.029","article-title":"Reactive oxygen species: a novel antimicrobial","volume":"51","author":"Dryden","year":"2018","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.vetmic.2022.109450_bib10","doi-asserted-by":"crossref","DOI":"10.12968\/jowc.2016.25.3.140","article-title":"A multi-centre clinical evaluation of reactive oxygen topical wound gel in 114 wounds","volume":"25","author":"Dryden","year":"2016","journal-title":"J. Wound Care"},{"key":"10.1016\/j.vetmic.2022.109450_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.689866","article-title":"Neutrophil-dependent immunity during pulmonary infections and inflammations","volume":"12","author":"Effah","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.vetmic.2022.109450_bib12","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1159\/000205281","article-title":"Mouse neutrophil extracellular traps in microbial infections","volume":"1","author":"Ermert","year":"2009","journal-title":"J. Innate Immun."},{"key":"10.1016\/j.vetmic.2022.109450_bib13","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1159\/000284367","article-title":"Neutrophil apoptosis: relevance to the innate immune response and inflammatory disease","volume":"2","author":"Fox","year":"2010","journal-title":"J. Innate Immun."},{"key":"10.1016\/j.vetmic.2022.109450_bib14","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02452-14","article-title":"Neisseria gonorrhoeae elicits extracellular traps in primary neutrophil culture while suppressing the oxidative burst","volume":"6","author":"Gunderson","year":"2015","journal-title":"mBio"},{"key":"10.1016\/j.vetmic.2022.109450_bib15","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1093\/femsre\/fuu009","article-title":"Mechanisms of group A Streptococcus resistance to reactive oxygen species","volume":"39","author":"Henningham","year":"2015","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.vetmic.2022.109450_bib16","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.cvfa.2012.03.010","article-title":"Update on control of Staphylococcus aureus and Streptococcus agalactiae for management of mastitis. The veterinary clinics of North America","volume":"28","author":"Keefe","year":"2012","journal-title":"Food Anim. Pract."},{"key":"10.1016\/j.vetmic.2022.109450_bib17","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.chom.2015.11.001","article-title":"Group B Streptococcus evades host immunity by degrading hyaluronan","volume":"18","author":"Kolar","year":"2015","journal-title":"Cell. Host. Microbe."},{"key":"10.1016\/j.vetmic.2022.109450_bib18","doi-asserted-by":"crossref","first-page":"2786","DOI":"10.3389\/fmicb.2018.02786","article-title":"Investigation of the role that NADH peroxidase plays in oxidative stress survival in group B Streptococcus","volume":"9","author":"Korir","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.vetmic.2022.109450_bib19","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3389\/fcimb.2017.00019","article-title":"Group B Streptococcus induces neutrophil recruitment to gestational tissues and elaboration of extracellular traps and nutritional immunity","volume":"7","author":"Kothary","year":"2017","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.vetmic.2022.109450_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens10050545","article-title":"An understanding of the global status of major bacterial pathogens of milk concerning bovine mastitis: a systematic review and meta-analysis (Scientometrics)","volume":"10","author":"Krishnamoorthy","year":"2021","journal-title":"Pathogens"},{"key":"10.1016\/j.vetmic.2022.109450_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004651","article-title":"Neutrophils: between host defence, immune modulation, and tissue injury","volume":"11","author":"Kruger","year":"2015","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.vetmic.2022.109450_bib22","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/9741838","article-title":"Using ROS as a second messenger, NADPH oxidase 2 mediates macrophage senescence via interaction with NF-kappaB during Pseudomonas aeruginosa infection","volume":"2018","author":"Li","year":"2018","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.vetmic.2022.109450_bib23","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4137\/JCD.S11038","article-title":"Regulation of human neutrophil apoptosis and lifespan in health and disease","volume":"7","author":"McCracken","year":"2014","journal-title":"J. Cell Death"},{"key":"10.1016\/j.vetmic.2022.109450_bib24","doi-asserted-by":"crossref","first-page":"373","DOI":"10.3389\/fcimb.2017.00373","article-title":"Neutrophils to the ROScue: mechanisms of NADPH oxidase activation and bacterial resistance","volume":"7","author":"Nguyen","year":"2017","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.vetmic.2022.109450_bib25","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1016\/j.molimm.2007.10.013","article-title":"Autoregulation mechanism of human neutrophil apoptosis during bacterial infection","volume":"45","author":"Ocana","year":"2008","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.vetmic.2022.109450_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.119836","article-title":"Inhibition of neutrophil elastase prevents neutrophil extracellular trap formation and rescues mice from endotoxic shock","volume":"238","author":"Okeke","year":"2020","journal-title":"Biomaterials"},{"key":"10.1016\/j.vetmic.2022.109450_bib27","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/nri.2017.105","article-title":"Neutrophil extracellular traps in immunity and disease","volume":"18","author":"Papayannopoulos","year":"2018","journal-title":"Nat. Rev. Immunology"},{"key":"10.1016\/j.vetmic.2022.109450_bib28","doi-asserted-by":"crossref","first-page":"484","DOI":"10.3389\/fimmu.2016.00484","article-title":"Neutrophils discriminate between lipopolysaccharides of different bacterial sources and selectively release neutrophil extracellular traps","volume":"7","author":"Pieterse","year":"2016","journal-title":"Front. Immunol."},{"key":"10.1016\/j.vetmic.2022.109450_bib29","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s13567-015-0196-x","article-title":"Neutrophil extracellular traps in sheep mastitis","volume":"46","author":"Pisanu","year":"2015","journal-title":"Vet. Res."},{"key":"10.1016\/j.vetmic.2022.109450_bib30","doi-asserted-by":"crossref","first-page":"9294","DOI":"10.3168\/jds.2017-13363","article-title":"Short communication: molecular epidemiology of Streptococcus agalactiae differs between countries","volume":"100","author":"Reyes","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.vetmic.2022.109450_bib31","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3389\/fcimb.2018.00159","article-title":"Bacterial adherence and dwelling probability: two drivers of early alveolar infection by Streptococcus pneumoniae identified in multi-level mathematical modeling","volume":"8","author":"Santos","year":"2018","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.vetmic.2022.109450_bib32","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.cvfa.2018.07.005","article-title":"Mammary gland immunobiology and resistance to mastitis. the veterinary clinics of North America","volume":"34","author":"Sordillo","year":"2018","journal-title":"Food Anim. Pract."},{"issue":"Suppl 2","key":"10.1016\/j.vetmic.2022.109450_bib33","article-title":"Immune complex-induced neutrophil functions: a focus on cell death","volume":"48","author":"Vermeren","year":"2018","journal-title":"Eur. J. Clin. Investig."},{"key":"10.1016\/j.vetmic.2022.109450_bib34","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1128\/CMR.00101-13","article-title":"Disease manifestations and pathogenic mechanisms of Group A Streptococcus","volume":"27","author":"Walker","year":"2014","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.vetmic.2022.109450_bib35","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1111\/j.1462-5822.2006.00857.x","article-title":"Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps","volume":"9","author":"Wartha","year":"2007","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.vetmic.2022.109450_bib36","doi-asserted-by":"crossref","first-page":"2784","DOI":"10.1016\/S2095-3119(20)63185-9","article-title":"Detection of antimicrobial resistance and virulence-related genes in Streptococcus uberis and Streptococcus parauberis isolated from clinical bovine mastitis cases in northwestern China","volume":"19","author":"Zhang","year":"2020","journal-title":"J. Integr. Agric."},{"key":"10.1016\/j.vetmic.2022.109450_bib37","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1093\/jac\/dku463","article-title":"Moving forward with reactive oxygen species involvement in antimicrobial lethality","volume":"70","author":"Zhao","year":"2015","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.vetmic.2022.109450_bib38","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.chom.2008.07.002","article-title":"The IL-8 protease SpyCEP\/ScpC of group A Streptococcus promotes resistance to neutrophil killing","volume":"4","author":"Zinkernagel","year":"2008","journal-title":"Cell Host Microbe"}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113522001201?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113522001201?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T23:17:45Z","timestamp":1759879065000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113522001201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":38,"alternative-id":["S0378113522001201"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2022.109450","relation":{},"ISSN":["0378-1135"],"issn-type":[{"value":"0378-1135","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of multiplicity of infection on the evasion of neutrophil killing by Streptococcus agalactiae isolated from clinical mastitis bovine","name":"articletitle","label":"Article Title"},{"value":"Veterinary Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetmic.2022.109450","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109450"}}