{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T03:07:27Z","timestamp":1788318447902,"version":"build-2803163510"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.vetmic.2022.109490","type":"journal-article","created":{"date-parts":[[2022,6,11]],"date-time":"2022-06-11T04:03:07Z","timestamp":1654920187000},"page":"109490","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Oral immunization of recombinant Saccharomyces cerevisiae expressing fiber-2 of fowl adenovirus serotype 4 induces protective immunity against homologous infection"],"prefix":"10.1016","volume":"271","author":[{"given":"Hongwei","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deping","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huixia","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhehan","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huliang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baiping","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyu","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhai","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetmic.2022.109490_bib1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1136\/vr.124.10.247","article-title":"Hydropericarditis syndrome in broiler chickens in Pakistan","volume":"124","author":"Anjum","year":"1989","journal-title":"Vet. Rec."},{"key":"10.1016\/j.vetmic.2022.109490_bib2","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/nature12726","article-title":"Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation","volume":"504","author":"Arpaia","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.vetmic.2022.109490_bib3","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1007\/s00705-012-1570-x","article-title":"Hydropericardium syndrome: current state and future developments","volume":"158","author":"Asthana","year":"2013","journal-title":"Arch. Virol."},{"key":"10.1016\/j.vetmic.2022.109490_bib4","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1023\/B:VERC.0000012115.86894.1e","article-title":"The hydropericardium syndrome in poultry--a current scenario","volume":"28","author":"Balamurugan","year":"2004","journal-title":"Vet. Res. Commun."},{"key":"10.1016\/j.vetmic.2022.109490_bib5","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s12250-020-00278-3","article-title":"Porcine immunoglobulin Fc fused P30\/P54 protein of African swine fever virus displaying on surface of S. cerevisiae elicit strong antibody production in swine","volume":"36","author":"Chen","year":"2021","journal-title":"Virol. Sin."},{"key":"10.1016\/j.vetmic.2022.109490_bib6","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/j.vaccine.2018.01.028","article-title":"Immunogenicity and protective efficacy of recombinant fiber-2 protein in protecting SPF chickens against fowl adenovirus 4","volume":"36","author":"Chen","year":"2018","journal-title":"Vaccine"},{"key":"10.1016\/j.vetmic.2022.109490_bib7","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1080\/03079458308436147","article-title":"Fowl adenoviruses: studies on aspects of the pathogenicity of six strains for 1-day-old chicks","volume":"12","author":"Cook","year":"1983","journal-title":"Avian Pathol."},{"key":"10.1016\/j.vetmic.2022.109490_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0145419","article-title":"Identification and functional characterization of glycosylation of recombinant human platelet-derived growth factor-BB in Pichia pastoris","volume":"10","author":"Dai","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.vetmic.2022.109490_bib9","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1136\/gutjnl-2018-317503","article-title":"Role of the microbiome in human development","volume":"68","author":"Dominguez-Bello","year":"2019","journal-title":"Gut"},{"key":"10.1016\/j.vetmic.2022.109490_bib10","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1002\/jbm.a.30470","article-title":"A GPIIb\/IIIa bioreactor for specific treatment of immune thrombocytopenic purpura, an autoimmune disease. Preparation, in vitro characterization, and preliminary proof-of-concept animal studies","volume":"75","author":"Emregul","year":"2005","journal-title":"J. Biomed. Mater. Res. A"},{"key":"10.1016\/j.vetmic.2022.109490_bib11","doi-asserted-by":"crossref","first-page":"2761","DOI":"10.1016\/S0264-410X(03)00117-8","article-title":"A subunit vaccine against the adenovirus egg-drop syndrome using part of its fiber protein","volume":"21","author":"Fingerut","year":"2003","journal-title":"Vaccine"},{"key":"10.1016\/j.vetmic.2022.109490_bib12","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/nrgastro.2012.156","article-title":"The role of the gut microbiota in nutrition and health","volume":"9","author":"Flint","year":"2012","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.vetmic.2022.109490_bib13","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1111\/jpn.12330","article-title":"Yeast cell wall and live yeast products and their combination in broiler diets formulated with weekly ingredient variations","volume":"99","author":"Fowler","year":"2015","journal-title":"J. Anim. Physiol. Anim. Nutr."},{"key":"10.1016\/j.vetmic.2022.109490_bib14","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1053\/rvsc.1999.0365","article-title":"Hydropericardium hepatitis syndrome of broiler poultry: current status of research","volume":"68","author":"Ganesh","year":"2000","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.vetmic.2022.109490_bib15","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0076-6879(02)50957-5","article-title":"Transformation of yeast by lithium acetate\/single-stranded carrier DNA\/polyethylene glycol method","volume":"350","author":"Gietz","year":"2002","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.vetmic.2022.109490_bib16","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.jviromet.2012.04.005","article-title":"Real-time PCR assay for universal detection and quantitation of all five species of fowl adenoviruses (FAdV-A to FAdV-E)","volume":"183","author":"Gunes","year":"2012","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.vetmic.2022.109490_bib17","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkv464","article-title":"YeastFab: the design and construction of standard biological parts for metabolic engineering in Saccharomyces cerevisiae","volume":"43","author":"Guo","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.vetmic.2022.109490_bib18","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1016\/j.cell.2019.08.010","article-title":"Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans","volume":"178","author":"Hagan","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.vetmic.2022.109490_bib19","article-title":"Viral infections, the microbiome, and probiotics","volume":"10","author":"Harper","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.vetmic.2022.109490_bib20","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/978-1-59745-277-9_22","article-title":"Phylogenetic analysis of adenovirus sequences","volume":"131","author":"Harrach","year":"2007","journal-title":"Methods Mol. Med."},{"key":"10.1016\/j.vetmic.2022.109490_bib21","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1080\/03079450050045440","article-title":"Detection and differentiation of avian adenoviruses: a review","volume":"29","author":"Hess","year":"2000","journal-title":"Avian Pathol."},{"key":"10.1016\/j.vetmic.2022.109490_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.virusres.2021.198552","article-title":"Development of a subunit vaccine based on fiber2 and hexon against fowl adenovirus serotype 4","volume":"305","author":"Hu","year":"2021","journal-title":"Virus Res."},{"key":"10.1016\/j.vetmic.2022.109490_bib23","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1089\/107999001300177475","article-title":"Cellular responses in chickens treated with IFN-alpha orally or inoculated with recombinant Marek\u2019s disease virus expressing IFN-alpha","volume":"21","author":"Jarosinski","year":"2001","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.vetmic.2022.109490_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2021.632218","article-title":"Oral immunization of recombinant lactococcus lactis and enterococcus faecalis expressing dendritic cell targeting peptide and hexon protein of fowl adenovirus 4 induces protective immunity against homologous infection","volume":"8","author":"Jia","year":"2021","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.vetmic.2022.109490_bib25","article-title":"A vaccine based on the receptor-binding domain of the spike protein expressed in glycoengineered Pichia pastoris targeting SARS-CoV-2 stimulates neutralizing and protective antibody responses","author":"Liu","year":"2021","journal-title":"Engineering"},{"key":"10.1016\/j.vetmic.2022.109490_bib26","article-title":"Sunitinib represses regulatory T cells to overcome immunotolerance in a murine model of hepatocellular cancer","volume":"7","author":"Liu","year":"2017","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.vetmic.2022.109490_bib27","doi-asserted-by":"crossref","DOI":"10.1038\/emi.2016.115","article-title":"Genetic characterization of novel fowl aviadenovirus 4 isolates from outbreaks of hepatitis-hydropericardium syndrome in broiler chickens in China","volume":"5","author":"Liu","year":"2016","journal-title":"Emerg. Microbes Infect."},{"key":"10.1016\/j.vetmic.2022.109490_bib28","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1021\/acs.bioconjchem.7b00738","article-title":"Targeted strategies for mucosal vaccination","volume":"29","author":"Longet","year":"2018","journal-title":"Bioconjug. Chem."},{"key":"10.1016\/j.vetmic.2022.109490_bib29","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1089\/10799900152434439","article-title":"Nomenclature of avian interferon proteins","volume":"21","author":"Lowenthal","year":"2001","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.vetmic.2022.109490_bib30","doi-asserted-by":"crossref","first-page":"444","DOI":"10.3389\/fimmu.2017.00444","article-title":"The length of N-glycans of recombinant H5N1 hemagglutinin influences the oligomerization and immunogenicity of vaccine antigen","volume":"8","author":"Maciola","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.vetmic.2022.109490_bib31","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1292\/jvms.001455","article-title":"Genetic characterization of fowl adenoviruses isolated from chickens with hydropericardium syndrome in Japan","volume":"71","author":"Mase","year":"2009","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.vetmic.2022.109490_bib32","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1099\/0022-1317-25-3-325","article-title":"Adenovirus antigens: a model system in mice for subunit vaccination","volume":"25","author":"Mautner","year":"1974","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2022.109490_bib33","first-page":"11","article-title":"Identification, pathogenicity of novel fowl adenovirus serotype 4 SDJN0105 in Shandong, China and immunoprotective evaluation of the newly developed inactivated oil-emulsion FAdV-4 vaccine","author":"Meng","year":"2019","journal-title":"Viruses"},{"key":"10.1016\/j.vetmic.2022.109490_bib34","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1089\/jir.2010.0123","article-title":"Recombinant chicken interferon-alpha inhibits H9N2 avian influenza virus replication in vivo by oral administration","volume":"31","author":"Meng","year":"2011","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.vetmic.2022.109490_bib35","doi-asserted-by":"crossref","first-page":"3702","DOI":"10.1172\/JCI93820","article-title":"Microbiota maintain colonic homeostasis by activating TLR2\/MyD88\/PI3K signaling in IL-10-producing regulatory B cells","volume":"129","author":"Mishima","year":"2019","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.vetmic.2022.109490_bib36","doi-asserted-by":"crossref","first-page":"389","DOI":"10.2307\/1592978","article-title":"The in vivo and in vitro effects of chicken interferon alpha on infectious bursal disease virus and Newcastle disease virus infection","volume":"45","author":"Mo","year":"2001","journal-title":"Avian Dis."},{"key":"10.1016\/j.vetmic.2022.109490_bib37","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/nri1777","article-title":"Mucosal vaccines: the promise and the challenge","volume":"6","author":"Neutra","year":"2006","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.vetmic.2022.109490_bib38","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00705-015-2635-4","article-title":"Phylogenetic and geographic analysis of fowl adenovirus field strains isolated from poultry in Poland","volume":"161","author":"Niczyporuk","year":"2016","journal-title":"Arch. Virol."},{"key":"10.1016\/j.vetmic.2022.109490_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101388","article-title":"Changes in the ceca microbiota of broilers vaccinated for coccidiosis or supplemented with salinomycin","volume":"100","author":"Orso","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.vetmic.2022.109490_bib40","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s11262-016-1393-z","article-title":"Molecular analysis of the hexon, penton base, and fiber-2 genes of Korean fowl adenovirus serotype 4 isolates from hydropericardium syndrome-affected chickens","volume":"53","author":"Park","year":"2017","journal-title":"Virus Genes"},{"key":"10.1016\/j.vetmic.2022.109490_bib41","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1089\/107999001317205204","article-title":"Chicken interferon type I inhibits infectious bronchitis virus replication and associated respiratory illness","volume":"21","author":"Pei","year":"2001","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.vetmic.2022.109490_bib42","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.pep.2012.01.012","article-title":"Expression and purification of soluble porcine CTLA-4 in yeast Pichia pastoris","volume":"82","author":"Peraino","year":"2012","journal-title":"Protein Expr. Purif."},{"key":"10.1016\/j.vetmic.2022.109490_bib43","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jnutbio.2018.08.005","article-title":"Intestinal anti-inflammatory effect of the probiotic Saccharomyces boulardii in DSS-induced colitis in mice: Impact on microRNAs expression and gut microbiota composition","volume":"61","author":"Rodriguez-Nogales","year":"2018","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.vetmic.2022.109490_bib44","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.meegid.2018.03.031","article-title":"A subunit vaccine based on fiber-2 protein provides full protection against fowl adenovirus serotype 4 and induces quicker and stronger immune responses than an inactivated oil-emulsion vaccine","volume":"61","author":"Ruan","year":"2018","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.vetmic.2022.109490_bib45","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.meegid.2018.03.031","article-title":"A subunit vaccine based on fiber-2 protein provides full protection against fowl adenovirus serotype 4 and induces quicker and stronger immune responses than an inactivated oil-emulsion vaccine","volume":"61","author":"Ruan","year":"2018","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.vetmic.2022.109490_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1099\/vir.0.003087-0","article-title":"Adenoviruses: update on structure and function","volume":"90","author":"Russell","year":"2009","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2022.109490_bib47","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.vaccine.2013.12.056","article-title":"Recombinant FAdV-4 fiber-2 protein protects chickens against hepatitis-hydropericardium syndrome (HHS)","volume":"32","author":"Schachner","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.vetmic.2022.109490_bib48","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/nature09907","article-title":"A diverse range of gene products are effectors of the type I interferon antiviral response","volume":"472","author":"Schoggins","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.vetmic.2022.109490_bib49","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0264-410X(95)00206-G","article-title":"Yeast expressing hepatitis B virus surface antigen determinants on its surface: implications for a possible oral vaccine","volume":"14","author":"Schreuder","year":"1996","journal-title":"Vaccine"},{"key":"10.1016\/j.vetmic.2022.109490_bib50","doi-asserted-by":"crossref","first-page":"7153","DOI":"10.1016\/j.vaccine.2012.10.013","article-title":"A subunit vaccine against hydropericardium syndrome using adenovirus penton capsid protein","volume":"30","author":"Shah","year":"2012","journal-title":"Vaccine"},{"key":"10.1016\/j.vetmic.2022.109490_bib51","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.anifeedsci.2017.11.010","article-title":"Yeast and yeast derivatives in feed additives and ingredients: sources, characteristics, animal responses, and quantification methods","volume":"235","author":"Shurson","year":"2018","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.vetmic.2022.109490_bib52","doi-asserted-by":"crossref","first-page":"7635","DOI":"10.1074\/jbc.271.13.7635","article-title":"A family of genes coding for two serologically distinct chicken interferons","volume":"271","author":"Sick","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.vetmic.2022.109490_bib53","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1111\/j.1365-2222.2009.03326.x","article-title":"Influence of early gut microbiota on the maturation of childhood mucosal and systemic immune responses","volume":"39","author":"Sjogren","year":"2009","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.vetmic.2022.109490_bib54","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.it.2008.04.002","article-title":"Revival of CD8+ Treg-mediated suppression","volume":"29","author":"Smith","year":"2008","journal-title":"Trends Immunol."},{"key":"10.1016\/j.vetmic.2022.109490_bib55","doi-asserted-by":"crossref","first-page":"759","DOI":"10.4142\/jvs.2018.19.6.759","article-title":"Hexon and fiber gene changes in an attenuated fowl adenovirus isolate from Malaysia in embryonated chicken eggs and its infectivity in chickens","volume":"19","author":"Sohaimi","year":"2018","journal-title":"J. Vet. Sci."},{"key":"10.1016\/j.vetmic.2022.109490_bib56","doi-asserted-by":"crossref","first-page":"6643","DOI":"10.1016\/j.psj.2020.08.063","article-title":"Research note: molecular relationship of the fowl adenovirus serotype 4 isolated from the contaminated live vaccine and wild strains isolated in China, 2013-2018","volume":"99","author":"Su","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.vetmic.2022.109490_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.meegid.2019.104017","article-title":"Pathogenicity of fowl adenovirus serotype 4 (FAdV-4) in chickens","volume":"75","author":"Sun","year":"2019","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.vetmic.2022.109490_bib58","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1016\/j.vaccine.2020.01.006","article-title":"Protection of chickens against hepatitis-hydropericardium syndrome and Newcastle disease with a recombinant Newcastle disease virus vaccine expressing the fowl adenovirus serotype 4 fiber-2 protein","volume":"38","author":"Tian","year":"2020","journal-title":"Vaccine"},{"key":"10.1016\/j.vetmic.2022.109490_bib59","doi-asserted-by":"crossref","first-page":"262","DOI":"10.2307\/1592616","article-title":"Characterization of fowl adenoviruses from outbreaks of inclusion body hepatitis\/hydropericardium syndrome in Chile","volume":"43","author":"Toro","year":"1999","journal-title":"Avian Dis."},{"key":"10.1016\/j.vetmic.2022.109490_bib60","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0734-9750(00)00031-8","article-title":"Genetic immobilization of proteins on the yeast cell surface","volume":"18","author":"Ueda","year":"2000","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.vetmic.2022.109490_bib61","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s13567-018-0525-y","article-title":"A novel monoclonal antibody efficiently blocks the infection of serotype 4 fowl adenovirus by targeting fiber-2","volume":"49","author":"Wang","year":"2018","journal-title":"Vet. Res."},{"key":"10.1016\/j.vetmic.2022.109490_bib62","doi-asserted-by":"crossref","first-page":"831","DOI":"10.3389\/fmicb.2020.00831","article-title":"Interactions among expressed MicroRNAs and mRNAs in the early stages of fowl adenovirus aerotype 4-infected leghorn male hepatocellular cells","volume":"11","author":"Wu","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.vetmic.2022.109490_bib63","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s13567-021-00907-z","article-title":"A novel fiber-2-edited live attenuated vaccine candidate against the highly pathogenic serotype 4 fowl adenovirus","volume":"52","author":"Xie","year":"2021","journal-title":"Vet. Res."},{"key":"10.1016\/j.vetmic.2022.109490_bib64","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s12934-015-0225-5","article-title":"Role of N-linked glycosylation in the secretion and enzymatic properties of Rhizopus chinensis lipase expressed in Pichia pastoris","volume":"14","author":"Yang","year":"2015","journal-title":"Microb. Cell Fact."},{"key":"10.1016\/j.vetmic.2022.109490_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetmic.2021.109250","article-title":"A fowl adenovirus serotype 4 (FAdV-4) Fiber2 subunit vaccine candidate provides complete protection against challenge with virulent FAdV-4 strain in chickens","volume":"263","author":"Yin","year":"2021","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2022.109490_bib66","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1016\/S2095-3119(19)62739-5","article-title":"Baculovirus-expressed FAdV-4 penton base protein protects chicken against hepatitis-hydropericardium syndrome","volume":"18","author":"Zhang","year":"2019","journal-title":"J. Integr. Agric."},{"key":"10.1016\/j.vetmic.2022.109490_bib67","article-title":"Pathogenicity and complete genome characterization of fowl adenoviruses isolated from chickens associated with inclusion body hepatitis and hydropericardium syndrome in China","volume":"10","author":"Zhao","year":"2015","journal-title":"PLoS One"}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113522001602?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113522001602?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T23:18:06Z","timestamp":1759879086000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113522001602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":67,"alternative-id":["S0378113522001602"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2022.109490","relation":{},"ISSN":["0378-1135"],"issn-type":[{"value":"0378-1135","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oral immunization of recombinant Saccharomyces cerevisiae expressing fiber-2 of fowl adenovirus serotype 4 induces protective immunity against homologous infection","name":"articletitle","label":"Article Title"},{"value":"Veterinary Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetmic.2022.109490","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109490"}}