{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T04:12:04Z","timestamp":1788408724471,"version":"build-2803163510"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T00:00:00Z","timestamp":1708905600000},"content-version":"am","delay-in-days":301,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20K10432"],"award-info":[{"award-number":["20K10432"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.vetmic.2023.109695","type":"journal-article","created":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T12:28:44Z","timestamp":1676550524000},"page":"109695","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Genetic and phenotypic analyses of mcr-harboring extended-spectrum \u03b2-lactamase-producing Escherichia coli isolates from companion dogs and cats in Japan"],"prefix":"10.1016","volume":"280","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9688-2006","authenticated-orcid":false,"given":"Mayo","family":"Yasugi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Hatoya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Motooka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Akiyoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Horie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shota","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terumasa","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetmic.2023.109695_bib1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1128\/JCM.38.1.40-43.2000","article-title":"Convenient test for screening metallo-beta-lactamase-producing gram-negative bacteria by using thiol compounds","volume":"38","author":"Arakawa","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.vetmic.2023.109695_bib2","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1185\/03007995.2015.1018989","article-title":"Colistin, mechanisms and prevalence of resistance","volume":"31","author":"Bialvaei","year":"2015","journal-title":"Curr. Med. Res. Opin."},{"key":"10.1016\/j.vetmic.2023.109695_bib3","doi-asserted-by":"crossref","first-page":"80","DOI":"10.3389\/fmicb.2020.00080","article-title":"Development of a novel mcr-6 to mcr-9 multiplex PCR and assessment of mcr-1 to mcr-9 occurrence in colistin-resistant Salmonella enterica isolates from environment, feed, animals and food (2011-2018) in Germany","volume":"11","author":"Borowiak","year":"2020","journal-title":"Front. Microbiol"},{"key":"10.1016\/j.vetmic.2023.109695_bib4","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1186\/1471-2105-10-421","article-title":"BLAST+: architecture and applications","volume":"10","author":"Camacho","year":"2009","journal-title":"BMC Bioinform."},{"key":"10.1016\/j.vetmic.2023.109695_bib5","first-page":"10","article-title":"Identification of novel mobilized colistin resistance gene mcr-9 in a multidrug-resistant, colistin-susceptible Salmonella enterica serotype Typhimurium isolate","author":"Carroll","year":"2019","journal-title":"mBio"},{"key":"10.1016\/j.vetmic.2023.109695_bib6","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1186\/s12917-020-02483-4","article-title":"The prevalence and mechanism of fluoroquinolone resistance in Escherichia coli isolated from swine farms in China","volume":"16","author":"Cheng","year":"2020","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.vetmic.2023.109695_bib7","unstructured":"Clinical and Laboratory Standards Institute , 2015. M07-A10. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically; Apporoved Standard, tenth ed.."},{"key":"10.1016\/j.vetmic.2023.109695_bib8","unstructured":"Clinical and Laboratory Standards Institute , 2020. M100, Performance Standards for Antimicrobial Susceptibility Testing, thirtieth ed."},{"key":"10.1016\/j.vetmic.2023.109695_bib9","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1128\/jb.149.2.726-732.1982","article-title":"Mobilization of nonconjugative antibiotic resistance plasmids in Haemophilus ducreyi","volume":"149","author":"Deneer","year":"1982","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.vetmic.2023.109695_bib10","series-title":"Kucers\u2019 the Use of Antibiotics","author":"Grayson","year":"2010"},{"key":"10.1016\/j.vetmic.2023.109695_bib11","first-page":"11","article-title":"Mobile colistin resistance (mcr) genes in cats and dogs and their zoonotic transmission risks","author":"Hamame","year":"2022","journal-title":"Pathogens"},{"key":"10.1016\/j.vetmic.2023.109695_bib12","first-page":"85","article-title":"Acquisition of mcr-1 and cocarriage of virulence genes in avian pathogenic Escherichia coli isolates from municipal wastewater influents in Japan","author":"Hayashi","year":"2019","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.vetmic.2023.109695_bib13","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1128\/AAC.47.7.2161-2168.2003","article-title":"Isolation and molecular characterization of nalidixic acid-resistant extraintestinal pathogenic Escherichia coli from retail chicken products","volume":"47","author":"Johnson","year":"2003","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.vetmic.2023.109695_bib14","first-page":"63","article-title":"mcr-9, an inducible gene encoding an acquired phosphoethanolamine transferase in Escherichia coli, and its origin","author":"Kieffer","year":"2019","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.vetmic.2023.109695_bib15","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0147-619X(90)90057-J","article-title":"Physical and genetic analyses of IncI2 plasmid R721: evidence for the presence of shufflon","volume":"23","author":"Komano","year":"1990","journal-title":"Plasmid"},{"key":"10.1016\/j.vetmic.2023.109695_bib16","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1080\/22221751.2021.1882884","article-title":"Prevalence and risk analysis of mobile colistin resistance and extended-spectrum beta-lactamase genes carriage in pet dogs and their owners: a population based cross-sectional study","volume":"10","author":"Lei","year":"2021","journal-title":"Emerg. Microbes Infect."},{"key":"10.1016\/j.vetmic.2023.109695_bib17","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S1473-3099(15)00424-7","article-title":"Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study","volume":"16","author":"Liu","year":"2016","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.vetmic.2023.109695_bib18","first-page":"5","article-title":"Multiple plasmid vectors mediate the spread of fosA3 in extended-spectrum-beta-lactamase-producing Enterobacterales isolates from retail vegetables in China","author":"Lv","year":"2020","journal-title":"mSphere"},{"key":"10.1016\/j.vetmic.2023.109695_bib19","doi-asserted-by":"crossref","first-page":"D8","DOI":"10.1093\/nar\/gkx1095","article-title":"Database resources of the National Center for Biotechnology Information","volume":"46","author":"Ncbi Resource Coordinators","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.vetmic.2023.109695_bib20","first-page":"7","article-title":"Complete genome sequence of the multidrug-resistant neonatal meningitis Escherichia coli serotype O75:H5:K1 strain mcjchv-1 (NMEC-O75)","author":"Nielsen","year":"2018","journal-title":"Microbiol. Resour. Announc."},{"key":"10.1016\/j.vetmic.2023.109695_bib21","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.ijantimicag.2016.11.026","article-title":"Extended-spectrum beta-lactamases, carbapenemases and the mcr-1 gene: is there a historical link?","volume":"49","author":"Rhouma","year":"2017","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.vetmic.2023.109695_bib22","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.vetmic.2019.02.006","article-title":"Co-occurrence of clinically relevant beta-lactamases and MCR-1 encoding genes in Escherichia coli from companion animals in Argentina","volume":"230","author":"Rumi","year":"2019","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2023.109695_bib23","article-title":"Complete genome sequence of an mcr-9-possessing Enterobacter asburiae strain isolated from a cat in Japan","volume":"10","author":"Sato","year":"2021","journal-title":"Microbiol. Resour. Announc."},{"key":"10.1016\/j.vetmic.2023.109695_bib24","article-title":"Complete genome sequence of an mcr-10-possessing Enterobacter roggenkampii strain isolated from a dog in Japan","volume":"10","author":"Sato","year":"2021","journal-title":"Microbiol. Resour. Announc."},{"key":"10.1016\/j.vetmic.2023.109695_bib25","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1038\/s41598-017-01082-y","article-title":"Elucidation of quantitative structural diversity of remarkable rearrangement regions, shufflons, in IncI2 plasmids","volume":"7","author":"Sekizuka","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.vetmic.2023.109695_bib26","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.ijid.2016.07.007","article-title":"Plasmid-mediated colistin resistance in Escherichia coli from the Arabian Peninsula","volume":"50","author":"Sonnevend","year":"2016","journal-title":"Int. J. Infect. Dis."},{"key":"10.1016\/j.vetmic.2023.109695_bib27","doi-asserted-by":"crossref","first-page":"5014","DOI":"10.1128\/AAC.00774-16","article-title":"Complete nucleotide sequence of an IncI2 plasmid coharboring blaCTX-M-55 and mcr-1","volume":"60","author":"Sun","year":"2016","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.vetmic.2023.109695_bib28","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/S1473-3099(16)00008-6","article-title":"Investigation of a plasmid genome database for colistin-resistance gene mcr-1","volume":"16","author":"Suzuki","year":"2016","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.vetmic.2023.109695_bib29","doi-asserted-by":"crossref","first-page":"14740","DOI":"10.1073\/pnas.1903002116","article-title":"Pandemic fluoroquinolone resistant Escherichia coli clone ST1193 emerged via simultaneous homologous recombinations in 11 gene loci","volume":"116","author":"Tchesnokova","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.vetmic.2023.109695_bib30","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1128\/JCM.43.6.2551-2558.2005","article-title":"Practical methods using boronic acid compounds for identification of class C beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli","volume":"43","author":"Yagi","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.vetmic.2023.109695_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0246482","article-title":"Whole-genome analyses of extended-spectrum or AmpC beta-lactamase-producing Escherichia coli isolates from companion dogs in Japan","volume":"16","author":"Yasugi","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.vetmic.2023.109695_bib32","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02097-22","article-title":"Emergence and transmission of plasmid-mediated mobile colistin resistance gene mcr-10 in humans and companion animals","author":"Yin","year":"2022","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.vetmic.2023.109695_bib33","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.plasmid.2016.04.001","article-title":"Complete nucleotide sequence of pH11, an IncHI2 plasmid conferring multi-antibiotic resistance and multi-heavy metal resistance genes in a clinical Klebsiella pneumoniae isolate","volume":"86","author":"Zhai","year":"2016","journal-title":"Plasmid"}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113523000470?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113523000470?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T23:21:10Z","timestamp":1759879270000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113523000470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":33,"alternative-id":["S0378113523000470"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2023.109695","relation":{},"ISSN":["0378-1135"],"issn-type":[{"value":"0378-1135","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genetic and phenotypic analyses of mcr-harboring extended-spectrum \u03b2-lactamase-producing Escherichia coli isolates from companion dogs and cats in Japan","name":"articletitle","label":"Article Title"},{"value":"Veterinary Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetmic.2023.109695","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109695"}}