{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T23:22:09Z","timestamp":1778800929568,"version":"3.51.4"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001381","name":"NRF","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001381","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.vetmic.2024.110192","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T20:19:39Z","timestamp":1721333979000},"page":"110192","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Oral immunization against foot-and-mouth disease virus using recombinant Saccharomyces cerevisiae with the improved expression of the codon-optimized VP1 fusion protein"],"prefix":"10.1016","volume":"296","author":[{"given":"Ngoc My Tieu","family":"Le","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kum-Kang","family":"So","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dae-Hyuk","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.vetmic.2024.110192_bib1","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1007\/s00705-015-2409-z","article-title":"An appraisal on the occurrence of foot-and-mouth disease virus serotypes in cattle and buffaloes, Pakistan","volume":"160","author":"Abubakar","year":"2015","journal-title":"Arch. Virol."},{"issue":"1","key":"10.1016\/j.vetmic.2024.110192_bib2","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s12934-018-0994-8","article-title":"Evaluation of cell-surface displayed synthetic consensus dengue EDIII cells as a potent oral vaccine candidate","volume":"17","author":"Bal","year":"2018","journal-title":"Microb. Cell Fact."},{"issue":"1","key":"10.1016\/j.vetmic.2024.110192_bib3","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12934-018-0876-0","article-title":"Comparative immunogenicity of preparations of yeast-derived dengue oral vaccine candidate","volume":"7","author":"Bal","year":"2018","journal-title":"Microb. Cell Fact."},{"issue":"3\u20134","key":"10.1016\/j.vetmic.2024.110192_bib4","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.vetimm.2004.12.008","article-title":"A peptide vaccine administered transcutaneously together with cholera toxin elicits potent neutralising anti-FMDV antibody responses","volume":"104","author":"Beignon","year":"2005","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.vetmic.2024.110192_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.virusres.2020.197909","article-title":"Foot-and-mouth disease virus: prospects for using knowledge of virus biology to improve control of this continuing global threat","volume":"281","author":"Belsham","year":"2020","journal-title":"Virus Res"},{"issue":"6","key":"10.1016\/j.vetmic.2024.110192_bib6","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1093\/nar\/20.6.1425","article-title":"Improved method for high efciency transformation of intact yeast cells.","volume":"20","author":"Gietz","year":"1992","journal-title":"Nucleic Acids Res"},{"issue":"4 Suppl","key":"10.1016\/j.vetmic.2024.110192_bib7","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1038\/nm1213","article-title":"Mucosal immunity and vaccines","volume":"11","author":"Holmgren","year":"2005","journal-title":"Nat. Med."},{"issue":"1","key":"10.1016\/j.vetmic.2024.110192_bib8","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/mi.2013.42","article-title":"Dendritic cells of the oral mucosa","volume":"7","author":"Hovav","year":"2014","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.vetmic.2024.110192_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1297-9716-44-116","article-title":"Foot-and-mouth disease: past, present and future","volume":"44","author":"Jamal","year":"2013","journal-title":"Vet. Res."},{"key":"10.1016\/j.vetmic.2024.110192_bib10","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.meegid.2018.01.020","article-title":"Molecular epidemiology, evolution and phylogeny of foot-and-mouth disease virus","volume":"59","author":"Jamal","year":"2018","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.vetmic.2024.110192_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetimm.2022.110497","article-title":"Evaluating the Immunogenicity of recombinant VP1 protein from the foot-and-mouth disease virus encapsulated in nanoliposome in guinea pig animal model","volume":"253","author":"Kazemi","year":"2022","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"7","key":"10.1016\/j.vetmic.2024.110192_bib12","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1271\/bbb.90941","article-title":"Surface-displayed expression of a neutralizing epitope of ApxIIA exotoxin in Saccharomyces cerevisiae and oral administration of it for protective immune responses against challenge by Actinobacillus pleuropneumoniae","author":"Kim","year":"2010","journal-title":"Biosci. Biotechnol. Biochem. 74"},{"key":"10.1016\/j.vetmic.2024.110192_bib13","doi-asserted-by":"crossref","first-page":"5787","DOI":"10.4049\/jimmunol.0903184","article-title":"The M cell-targeting ligand promotes antigen delivery and induces antigen-specific immune responses in mucosal vaccination","volume":"185","author":"Kim","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.vetmic.2024.110192_bib14","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.jconrel.2014.05.060","article-title":"Buccal and sublingual vaccine delivery","volume":"190","author":"Kraan","year":"2014","journal-title":"J. Control Release"},{"issue":"2","key":"10.1016\/j.vetmic.2024.110192_bib15","doi-asserted-by":"crossref","DOI":"10.1093\/femsyr\/foz007","article-title":"Yeast-based vaccines: New perspective in vaccine development and application","volume":"19","author":"Kumar","year":"2019","journal-title":"FEMS Yeast Res"},{"issue":"1","key":"10.1016\/j.vetmic.2024.110192_bib16","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s00253-023-12902-9","article-title":"Expression of virus-like particles (VLPs) of foot-and-mouth disease virus (FMDV) using Saccharomyces cerevisiae","volume":"108","author":"Le","year":"2024","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"4","key":"10.1016\/j.vetmic.2024.110192_bib17","first-page":"537","article-title":"Production of functional mouse interferon gamma from recombinant Saccharomyces","volume":"13","author":"Lim","year":"2003","journal-title":"cerevisiasiae. J. Microbiol. Biotechnol."},{"key":"10.1016\/j.vetmic.2024.110192_bib18","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1021\/acs.bioconjchem.7b00738","article-title":"Targeted strategies for mucosal vaccination","volume":"29","author":"Longet","year":"2018","journal-title":"Bioconjug. Chem."},{"issue":"11","key":"10.1016\/j.vetmic.2024.110192_bib19","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.3390\/vaccines10111817","article-title":"Development of foot-and-mouth disease vaccines in recent years","volume":"10","author":"Lu","year":"2022","journal-title":"Vaccin. (Basel)"},{"issue":"21","key":"10.1016\/j.vetmic.2024.110192_bib20","doi-asserted-by":"crossref","first-page":"2446","DOI":"10.1016\/j.vaccine.2014.02.092","article-title":"Emergence of antigenic variants of foot-and-mouth disease virus serotype O in Ecuador and preliminary evaluation of a field strain as a vaccine candidate","volume":"32","author":"Maradei","year":"2014","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.vetmic.2024.110192_bib21","first-page":"19","article-title":"Characterization of yeast protein enzymatic hydrolysis and autolysis in Saccharomyces cerevisiae and Kluyveromyces marxianus","volume":"5","author":"Mirzaeia","year":"2015","journal-title":"J. Fbt. IAU"},{"issue":"101","key":"10.1016\/j.vetmic.2024.110192_bib22","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1016\/j.vaccine.2010.12.127","article-title":"Evaluation of cross-protection between O1 Manisa and O1 Campos in cattle vaccinated with foot-and-mouth disease virus vaccine incorporating different payloads of inactivated O1 Manisa antigen","volume":"29","author":"Nagendrakumar","year":"2011","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.vetmic.2024.110192_bib23","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/nri1777","article-title":"Mucosal vaccines: the promise and the challenge","volume":"6","author":"Neutra","year":"2006","journal-title":"Nat. Rev. Immunol."},{"issue":"2","key":"10.1016\/j.vetmic.2024.110192_bib24","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.pep.2013.01.009","article-title":"Expression and purifcation of an immunogenic dengue virus epitope using a synthetic consensus sequence of envelope domain III and Saccharomyces cerevisiae.","volume":"88","author":"Nguyen","year":"2013","journal-title":"Protein Expr. Purif."},{"issue":"1","key":"10.1016\/j.vetmic.2024.110192_bib25","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jbiosc.2014.06.005","article-title":"Expression and characterization of an M cell-specifc ligand-fused dengue virus tetravalent epitope using Saccharomyces cerevisiae","volume":"119","author":"Nguyen","year":"2015","journal-title":"J. Biosci. Bioeng."},{"issue":"10","key":"10.1016\/j.vetmic.2024.110192_bib26","doi-asserted-by":"crossref","first-page":"6538","DOI":"10.4049\/jimmunol.0901480","article-title":"A rice-based oral cholera vaccine induces macaque-specific systemic neutralizing antibodies but does not influence pre-existing intestinal immunity","volume":"183","author":"Nochi","year":"2009","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.vetmic.2024.110192_bib27","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s40259-022-00575-1","article-title":"Current Progress and Challenges in the Study of Adjuvants for Oral Vaccines","volume":"37","author":"Ou","year":"2023","journal-title":"BioDrugs"},{"issue":"1","key":"10.1016\/j.vetmic.2024.110192_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3934\/microbiol.2020001","article-title":"Saccharomyces cerevisiae and its industrial applications","volume":"6","author":"Parapouli","year":"2020","journal-title":"AIMS Microbiol"},{"key":"10.1016\/j.vetmic.2024.110192_bib29","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1364-3703.2011.00742.x","article-title":"Characterization of CpSte11, a MAPKKK gene of Cryphonectria parasitica, and initial evidence of its involvement in the pheromone response pathway","volume":"13","author":"Park","year":"2012","journal-title":"Mol. Plant Pathol."},{"issue":"46","key":"10.1016\/j.vetmic.2024.110192_bib30","doi-asserted-by":"crossref","first-page":"6199","DOI":"10.1016\/j.vaccine.2015.10.003","article-title":"Oral application of freeze-dried yeast particles expressing the PCV2b Cap protein on their surface induce protection to subsequent PCV2b challenge in vivo","volume":"33","author":"Patterson","year":"2015","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.vetmic.2024.110192_bib31","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.virusres.2013.03.018","article-title":"VP1 protein of Foot-and-mouth disease virus (FMDV) impairs baculovirus surface display","volume":"175","author":"Peralta","year":"2013","journal-title":"Virus Res"},{"key":"10.1016\/j.vetmic.2024.110192_bib32","first-page":"333","article-title":"Foot-and-mouth disease","volume":"vol. 2","author":"Pereira","year":"1981"},{"issue":"6","key":"10.1016\/j.vetmic.2024.110192_bib33","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1080\/21655979.2016.1208868","article-title":"Agroinfiltration contributes to VP1 recombinant protein degradation","volume":"7","author":"Pillay","year":"2016","journal-title":"Bioengineered"},{"issue":"1","key":"10.1016\/j.vetmic.2024.110192_bib34","first-page":"1","article-title":"Developing vaccines against foot-and-mouth disease: a biotechnological approach","volume":"73","author":"Shahriari","year":"2018","journal-title":"Arch. Razi Inst."},{"issue":"3","key":"10.1016\/j.vetmic.2024.110192_bib35","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1128\/AEM.67.3.1280-1283.2001","article-title":"Enhanced iron uptake of Saccharomyces cerevisiae by heterologous expression of a tadpole ferritin gene","volume":"67","author":"Shin","year":"2001","journal-title":"Appl. Environ. Microbiol."},{"issue":"3","key":"10.1016\/j.vetmic.2024.110192_bib36","doi-asserted-by":"crossref","DOI":"10.1093\/femsyr\/foab018","article-title":"Yeasts as a promising delivery platform for DNA and RNA vaccines","volume":"21","author":"Silva","year":"2021","journal-title":"FEMS Yeast Res"},{"issue":"8","key":"10.1016\/j.vetmic.2024.110192_bib37","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.3390\/vaccines11081334","article-title":"RNA Vaccines: Yeast as a Novel Antigen Vehicle","volume":"11","author":"Silva","year":"2023","journal-title":"Vaccin. (Basel)"},{"issue":"9","key":"10.1016\/j.vetmic.2024.110192_bib38","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1007\/s10529-021-03161-7","article-title":"Expression of an immunocomplex consisting of Fc fragment fused with a consensus dengue envelope domain III in Saccharomyces cerevisiae","volume":"43","author":"So","year":"2021","journal-title":"Biotechnol. Lett."},{"issue":"1","key":"10.1016\/j.vetmic.2024.110192_bib39","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12934-023-02065-7","article-title":"Improving expression and assembly of difficult-to-express heterologous proteins in Saccharomyces cerevisiae by culturing at a sub-physiological temperature","volume":"22","author":"So","year":"2023","journal-title":"Microb. Cell Fact."},{"key":"10.1016\/j.vetmic.2024.110192_bib40","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.jconrel.2022.04.032","article-title":"Yeast as carrier for drug delivery and vaccine construction","volume":"346","author":"Tan","year":"2022","journal-title":"J. Control Release"},{"issue":"7","key":"10.1016\/j.vetmic.2024.110192_bib41","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/yea.1676","article-title":"Baker\u2019s yeast expressing the Japanese encephalitis virus envelope protein on its cell surface: Induction of an antigen-specific but non-neutralizing antibody response","volume":"26","author":"Upadhyaya","year":"2009","journal-title":"Yeast"},{"key":"10.1016\/j.vetmic.2024.110192_bib42","doi-asserted-by":"crossref","first-page":"262","DOI":"10.3389\/fbioe.2019.00262","article-title":"Engineering the yeast Saccharomyces cerevisiae for the production of L-(+)-Ergothioneine","volume":"7","author":"van der Hoek","year":"2019","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"8","key":"10.1016\/j.vetmic.2024.110192_bib43","article-title":"Identification of short hairpin RNA targeting foot-and-mouth disease virus with transgenic bovine fetal epithelium cells","volume":"7","author":"Wang","year":"2012","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.vetmic.2024.110192_bib44","article-title":"Protection against foot-and mouth disease virus in guinea pigs via oral administration of recombinant Lactobacillus plantarum expressing VP1","volume":"10","author":"Wang","year":"2015","journal-title":"PLoS One"},{"issue":"1\u20133","key":"10.1016\/j.vetmic.2024.110192_bib45","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jbiotec.2004.04.036","article-title":"Economic aspects of commercial manufacture of biopharmaceuticals","volume":"113","author":"Werner","year":"2004","journal-title":"J. Biotechnol."},{"issue":"2","key":"10.1016\/j.vetmic.2024.110192_bib46","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1006\/viro.1998.9590","article-title":"Induction of a protective antibody response to foot and mouth disease virus in mice following oral or parenteral immunization with alfalfa transgenic plants expressing the viral structural protein VP1","volume":"255","author":"Wigdorovitz","year":"1999","journal-title":"Virology"},{"issue":"1","key":"10.1016\/j.vetmic.2024.110192_bib47","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1006\/viro.2000.0607","article-title":"Plasmids encoding foot-and-mouth disease virus VP1 epitopes elicited immune responses in mice and swine and protected swine against viral infection","volume":"278","author":"Wong","year":"2000","journal-title":"Virology"},{"key":"10.1016\/j.vetmic.2024.110192_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2022.937409","article-title":"Foot-and-mouth disease virus VP1 promotes viral replication by regulating the expression of chemokines and GBP1","volume":"9","author":"Yang","year":"2022","journal-title":"Front. Vet. Sci."}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113524002141?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113524002141?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T01:03:21Z","timestamp":1722819801000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113524002141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":48,"alternative-id":["S0378113524002141"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2024.110192","relation":{},"ISSN":["0378-1135"],"issn-type":[{"value":"0378-1135","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oral immunization against foot-and-mouth disease virus using recombinant Saccharomyces cerevisiae with the improved expression of the codon-optimized VP1 fusion protein","name":"articletitle","label":"Article Title"},{"value":"Veterinary Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetmic.2024.110192","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"110192"}}