{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T22:38:46Z","timestamp":1793313526045,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012962","name":"National Fund for Environmental Protection and Water Management","doi-asserted-by":"publisher","award":["5.1.1"],"award-info":[{"award-number":["5.1.1"]}],"id":[{"id":"10.13039\/100012962","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.vetmic.2025.110682","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T06:35:20Z","timestamp":1754980520000},"page":"110682","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Characterization of the bacterial ocular surface microbiota of European bison (Bison bonasus) and their association with infectious keratoconjunctivitis"],"prefix":"10.1016","volume":"309","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9490-8241","authenticated-orcid":false,"given":"Katarzyna","family":"Filip-Hutsch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewelina","family":"Kwiecie\u0144","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u0142","family":"Czopowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota","family":"\u017babicka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Bednarek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Anusz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanda","family":"Olech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksander W.","family":"Demiaszkiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Rzewuska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetmic.2025.110682_bib1","series-title":"Statistics with Confidence: Confidence Intervals and Statistical Guidelines","first-page":"46","author":"Altman","year":"2000"},{"key":"10.1016\/j.vetmic.2025.110682_bib2","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.cvfa.2009.10.002","article-title":"Moraxella bovoculi and infectious bovine keratoconjunctivitis: cause or coincidence?","volume":"26","author":"Angelos","year":"2010","journal-title":"Vet. Clin. N. Am. Food Anim. Pr."},{"key":"10.1016\/j.vetmic.2025.110682_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetmic.2023.109752","article-title":"Investigation of the pathogens contributing to naturally occurring outbreaks of infectious bovine keratoconjunctivitis (pinkeye) using next generation sequencing","volume":"282","author":"Anis","year":"2023","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2025.110682_bib4","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1097\/ICL.0000000000000803","article-title":"An 18-Year overview of serratia marcescens ocular infection","volume":"47","author":"Atta","year":"2021","journal-title":"Eye Contact Lens"},{"key":"10.1016\/j.vetmic.2025.110682_bib5","series-title":"Essential Epidemiology: An Introduction for Students and Health Professionals","author":"Bain","year":"2021"},{"issue":"10","key":"10.1016\/j.vetmic.2025.110682_bib6","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.3389\/fmicb.2019.03006","article-title":"moraxella catarrhalis promotes stable polymicrobial biofilms with the major otopathogens","volume":"15","author":"Bair","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.vetmic.2025.110682_bib7","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1136\/vr.118.8.204","article-title":"Microbial flora of the eye of cattle","volume":"118","author":"Barber","year":"1986","journal-title":"Vet. Rec."},{"key":"10.1016\/j.vetmic.2025.110682_bib8","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s42523-021-00079-3","article-title":"Longitudinal assessment of the bovine ocular bacterial community dynamics in calves","volume":"3","author":"Bartenslager","year":"2021","journal-title":"Anim. Micro"},{"key":"10.1016\/j.vetmic.2025.110682_bib9","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.3390\/microorganisms11092143","article-title":"lelliottia amnigena and pseudomonas putida coinfection associated with a critical SARS-CoV-2 infection: a case report","volume":"11","author":"Birlutiu","year":"2023","journal-title":"Microorganisms"},{"key":"10.1016\/j.vetmic.2025.110682_bib10","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1007\/s15010-014-0647-8","article-title":"acinetobacter junii as an aetiological agent of corneal ulcer","volume":"42","author":"Broniek","year":"2014","journal-title":"Infection"},{"key":"10.1016\/j.vetmic.2025.110682_bib11","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3390\/microorganisms7080259","article-title":"Anatomic characterization of the ocular surface microbiome in children","volume":"7","author":"Cavuoto","year":"2019","journal-title":"Microorganisms"},{"key":"10.1016\/j.vetmic.2025.110682_bib12","doi-asserted-by":"crossref","first-page":"949","DOI":"10.2460\/ajvr.1994.55.07.949","article-title":"Conjunctival microbial flora of clinically normal pigs","volume":"55","author":"Davidson","year":"1994","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2025.110682_bib13","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1007\/s11686-020-00243-w","article-title":"The nematodes thelazia gulosa railiet and henry, 1910 and thelazia skrjabini erschov, 1928 as a cause of blindness in european bison (bison bonasus) in Poland","volume":"65","author":"Demiaszkiewicz","year":"2020","journal-title":"Acta Parasitol."},{"key":"10.1016\/j.vetmic.2025.110682_bib14","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1186\/s12917-021-03057-8","article-title":"Pathogens with potential impact on reproduction in captive and free-ranging european bison (bison bonasus) in Poland - a serological survey","volume":"17","author":"Didkowska","year":"2021","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.vetmic.2025.110682_bib15","doi-asserted-by":"crossref","first-page":"197","DOI":"10.5604\/12321966.1203878","article-title":"pantoea agglomerans: a mysterious bacterium of evil and good. Part III. Deleterious effects: infections of humans, animals and plants","volume":"23","author":"Dutkiewicz","year":"2016","journal-title":"Ann. Agric. Environ. Med."},{"key":"10.1016\/j.vetmic.2025.110682_bib16","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1136\/vr.125.10.253","article-title":"Ovine infectious keratoconjunctivitis: a microbiological study of clinically unaffected and affected sheep's eyes with special reference to mycoplasma conjunctivae","volume":"125","author":"Egwu","year":"1989","journal-title":"Vet. Rec."},{"key":"10.1016\/j.vetmic.2025.110682_bib17","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s12348-023-00363-0","article-title":"Successful treatment of multidrug-resistant pseudomonas aeruginosa keratitis with meropenem eye drops \u2014 a case report","volume":"13","author":"Elhardt","year":"2023","journal-title":"J. Ophthal. Inflamm. Infect."},{"key":"10.1016\/j.vetmic.2025.110682_bib18","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-27191-x","article-title":"The occurrence and molecular identification of thelazia spp. In european bison (bison bonasus) in the bieszczady mountains","volume":"12","author":"Filip-Hutsch","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.vetmic.2025.110682_bib19","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1186\/s12917-024-04375-3","article-title":"Infectious keratoconjunctivitis in european bison (bison bonasus) in Poland: risk factors, epidemiology and anatomopathological changes with analysis of potential role of thelazia nematodes in the disease development","volume":"20","author":"Filip-Hutsch","year":"2024","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.vetmic.2025.110682_bib20","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/s42523-023-00282-4","article-title":"Alterations to the bovine bacterial ocular surface microbiome in the context of infectious bovine keratoconjunctivitis","volume":"5","author":"Gafen","year":"2023","journal-title":"Anim. Micro"},{"key":"10.1016\/j.vetmic.2025.110682_bib21","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s12917-017-0972-0","article-title":"Infectious keratoconjunctivitis in wild caprinae: merging field observations and molecular analyses sheds light on factors shaping outbreak dynamics","volume":"13","author":"Gelormini","year":"2016","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.vetmic.2025.110682_bib22","doi-asserted-by":"crossref","first-page":"335","DOI":"10.20506\/rst.21.2.1338","article-title":"Infectious keratoconjunctivitis of ibex, chamois and other caprinae","volume":"21","author":"Giacometti","year":"2002","journal-title":"Rev. Sci. Tech. Oie."},{"key":"10.1016\/j.vetmic.2025.110682_bib23","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.vetmic.2008.04.018","article-title":"Ribosomal RNA-based analysis of the bacterial flora from the conjunctivae of cattle with bovine keratoconjunctivitis (BKC)","volume":"131","author":"Hare","year":"2008","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.vetmic.2025.110682_bib24","doi-asserted-by":"crossref","first-page":"643.e7","DOI":"10.1016\/j.cmi.2016.04.008","article-title":"Defining the normal core microbiome of conjunctival microbial communities","volume":"22","author":"Huang","year":"2016","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.vetmic.2025.110682_bib25","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1128\/CMR.00039-09","article-title":"The genus aeromonas: taxonomy, pathogenicity, and infection","volume":"23","author":"Janda","year":"2010","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.vetmic.2025.110682_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijantimicag.2023.106848","article-title":"One health and global health view of antimicrobial susceptibility through the \"eye\" of aeromonas: systematic review and meta-analysis","volume":"62","author":"Jones","year":"2023","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.vetmic.2025.110682_bib27","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF03193569","article-title":"Body mass and measurements of the european bison during postnatal development","volume":"47","author":"Krasi\u0144ska","year":"2002","journal-title":"Acta Theriol."},{"key":"10.1016\/j.vetmic.2025.110682_bib28","series-title":"The nature monograph","article-title":"European bison","author":"Krasi\u0144ska","year":"2013"},{"key":"10.1016\/j.vetmic.2025.110682_bib29","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1093\/tas\/txy138","article-title":"Survey of cow-calf producer perspectives on management strategies and industry challenges. Part 1: handling practices, and health and industry challenges","volume":"3","author":"Martin","year":"2019","journal-title":"Transl. Anim. Sci."},{"key":"10.1016\/j.vetmic.2025.110682_bib30","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.01289-22","article-title":"acinetobacter baumannii sampled from cattle and pigs represent novel clones","volume":"10","author":"Mateo-Estrada","year":"2022","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.vetmic.2025.110682_bib31","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/vop.12348","article-title":"Evaluation of conjunctival bacterial flora in a herd of goats in the midwestern United States","volume":"20","author":"Meekins","year":"2019","journal-title":"Vet. Ophthalmol."},{"key":"10.1016\/j.vetmic.2025.110682_bib32","doi-asserted-by":"crossref","first-page":"773","DOI":"10.2460\/ajvr.1988.49.06.773","article-title":"Prevalence of ocular microorganisms in hospitalized and stabled horses","volume":"49","author":"Moore","year":"1988","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetmic.2025.110682_bib33","doi-asserted-by":"crossref","first-page":"9880","DOI":"10.1038\/s41598-017-10494-9","article-title":"Temporal stability and composition of the ocular surface microbiome","volume":"7","author":"Ozkan","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.vetmic.2025.110682_bib34","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.3390\/microorganisms8071033","article-title":"Current evidence on the ocular surface microbiota and related diseases","volume":"8","author":"Petrillo","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.vetmic.2025.110682_bib35","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.cimid.2008.04.001","article-title":"Moraxella bovis pathogenicity: an update","volume":"31","author":"Postma","year":"2008","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"10.1016\/j.vetmic.2025.110682_bib36","unstructured":"J. Raczy\u0144ski, European Bison Pedigree Book (Ksi\u0119ga rodowodowa \u017cubr\u00f3w, in Polish). Bialowieza: Bia\u0142owieski Park Narodowy, Bialowieza, 2022, pp. 1\u20138."},{"key":"10.1016\/j.vetmic.2025.110682_bib37","first-page":"56","article-title":"Keratitis in reindeer: relation to bacterial infections","volume":"18","author":"Rehbinder","year":"1986","journal-title":"Acta Vet. Scand."},{"key":"10.1016\/j.vetmic.2025.110682_bib38","doi-asserted-by":"crossref","DOI":"10.1099\/jmmcr.0.005094","article-title":"aeromonas species endogenous endophthalmitis","volume":"4","author":"Ryan","year":"2017","journal-title":"JMM Case Rep."},{"key":"10.1016\/j.vetmic.2025.110682_bib39","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s12917-018-1338-y","article-title":"Infectious keratoconjunctivitis in semi-domesticated eurasian tundra reindeer (rangifer tarandus tarandus): microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2","volume":"14","author":"S\u00e1nchez Romano","year":"2018","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.vetmic.2025.110682_bib40","doi-asserted-by":"crossref","first-page":"685","DOI":"10.14737\/journal.aavs\/2015\/3.12.685.688","article-title":"Bacteria associated with conjunctivitis in bubalus arnee fulvus (Swamp Buffalo) in nagaland","volume":"3","author":"Singh","year":"2015","journal-title":"Adv. Anim. Vet. Sci."},{"key":"10.1016\/j.vetmic.2025.110682_bib41","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3341\/kjo.2007.21.1.45","article-title":"Endogenous aeromonas hydrophila endophthalmitis in an immunocompromised patient","volume":"21","author":"Sohn","year":"2007","journal-title":"Korean J. Ophthalmol."},{"key":"10.1016\/j.vetmic.2025.110682_bib42","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1097\/IAE.0000000000000509","article-title":"Endophthalmitis caused by serratia marcenscens: clinical features, antibiotic susceptibilities, and treatment outcomes","volume":"35","author":"Sridhar","year":"2015","journal-title":"Retina"},{"key":"10.1016\/j.vetmic.2025.110682_bib43","first-page":"159","article-title":"Conjunctival flora of normal Thai swamp buffalo","volume":"18","author":"Tantivanich","year":"1988","journal-title":"Thai Vet. Med."},{"issue":"7164","key":"10.1016\/j.vetmic.2025.110682_bib44","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1038\/nature06244","article-title":"The human microbiome project","volume":"449","author":"Turnbaugh","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.vetmic.2025.110682_bib45","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1097\/ICB.0b013e31818a46c0","article-title":"enterobacter amnigenus endophthalmitis","volume":"3","author":"Westerfeld","year":"2009","journal-title":"Retin. Cases Brief. Rep."},{"key":"10.1016\/j.vetmic.2025.110682_bib46","doi-asserted-by":"crossref","first-page":"11","DOI":"10.4098\/AT.arch.84-9","article-title":"Teeth eruption in the european bison","volume":"29","author":"W\u0119grzyn","year":"1984","journal-title":"Acta Theriol."},{"key":"10.1016\/j.vetmic.2025.110682_bib47","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.exer.2013.06.003","article-title":"Characterization of the normal microbiota of the ocular surface","volume":"117","author":"Willcox","year":"2013","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.vetmic.2025.110682_bib48","series-title":"Biostatistical analysis","first-page":"559","author":"Zar","year":"2010"},{"key":"10.1016\/j.vetmic.2025.110682_bib49","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.jtos.2020.07.007","article-title":"Assessing the ocular surface microbiome in severe ocular surface diseases","volume":"18","author":"Zilliox","year":"2020","journal-title":"Ocul. Surf."}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113525003177?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113525003177?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T14:06:15Z","timestamp":1772805975000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113525003177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":49,"alternative-id":["S0378113525003177"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2025.110682","relation":{},"ISSN":["0378-1135"],"issn-type":[{"value":"0378-1135","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of the bacterial ocular surface microbiota of European bison (Bison bonasus) and their association with infectious keratoconjunctivitis","name":"articletitle","label":"Article Title"},{"value":"Veterinary Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetmic.2025.110682","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"110682"}}