{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T21:26:05Z","timestamp":1789161965666,"version":"build-2803163510"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008828","name":"Heilongjiang Bayi Agricultural University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008828","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Microbiology"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.vetmic.2025.110823","type":"journal-article","created":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T08:03:16Z","timestamp":1764403396000},"page":"110823","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Resveratrol can inhibit porcine reproductive and respiratory syndrome virus infection in vitro and in vivo by inhibiting PI3K\/Akt signaling pathway"],"prefix":"10.1016","volume":"312","author":[{"given":"Yaping","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenshuang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinqi","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoyu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meilong","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingbing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongbo","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.vetmic.2025.110823_bib1","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.2174\/0929867311320100009","article-title":"Anti-inflammatory and antioxidant effects of resveratrol in healthy smokers a randomized, double-blind, placebo-controlled, cross-over trial","volume":"20","author":"Bo","year":"2013","journal-title":"Curr. Med Chem."},{"issue":"9","key":"10.1016\/j.vetmic.2025.110823_bib2","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.01025-23","article-title":"Astrovirus replication is dependent on induction of double-membrane vesicles through a PI3K-dependent, LC3-independent pathway","volume":"97","author":"Bub","year":"2023","journal-title":"J. Virol."},{"issue":"7","key":"10.1016\/j.vetmic.2025.110823_bib3","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.3390\/v15071442","article-title":"Progress in PRRSV infection and adaptive immune response. mechanisms","volume":"15","author":"Cai","year":"2023","journal-title":"Viruses"},{"key":"10.1016\/j.vetmic.2025.110823_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2024.106712","article-title":"Antiviral activity and underlying mechanisms of baicalin against porcine reproductive and respiratory syndrome virus in vitro","volume":"193","author":"Chang","year":"2024","journal-title":"Micro Pathog."},{"issue":"1","key":"10.1016\/j.vetmic.2025.110823_bib5","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1186\/s12951-023-02129-1","article-title":"Bone-targeting exosome nanoparticles activate Keap1\/Nrf2\/GPX4 signaling pathway to induce ferroptosis in osteosarcoma cells","volume":"21","author":"Chen","year":"2023","journal-title":"J. Nanobiotechnology"},{"issue":"1","key":"10.1016\/j.vetmic.2025.110823_bib6","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/cr.2013.153","article-title":"Chaperone-mediated autophagy: roles in disease and aging","volume":"24","author":"Cuervo","year":"2014","journal-title":"Cell Res"},{"issue":"5","key":"10.1016\/j.vetmic.2025.110823_bib7","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"issue":"7784","key":"10.1016\/j.vetmic.2025.110823_bib8","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/s41586-019-1707-0","article-title":"FSP1 is a glutathione-independent ferroptosis suppressor","volume":"575","author":"Doll","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.vetmic.2025.110823_bib9","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.lfs.2018.06.028","article-title":"Resveratrol: an overview of its anti-cancer mechanisms","volume":"207","author":"Elshaer","year":"2018","journal-title":"Life Sci."},{"issue":"7","key":"10.1016\/j.vetmic.2025.110823_bib10","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1039\/C5MB00101C","article-title":"The PI3K\/AKT\/mTOR interactive pathway","volume":"11","author":"Ersahin","year":"2015","journal-title":"Mol. Biosyst."},{"issue":"2","key":"10.1016\/j.vetmic.2025.110823_bib11","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.antiviral.2004.03.002","article-title":"3,4\u2032,5-Trihydroxy-trans-stilbene (resveratrol) inhibits human cytomegalovirus replication and virus-induced cellular signaling","volume":"63","author":"Evers","year":"2004","journal-title":"Antivir. Res"},{"issue":"1-2","key":"10.1016\/j.vetmic.2025.110823_bib12","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.virusres.2010.07.030","article-title":"The PRRSV replicase: exploring the multifunctionality of an intriguing set of nonstructural proteins","volume":"154","author":"Fang","year":"2010","journal-title":"Virus Res"},{"key":"10.1016\/j.vetmic.2025.110823_bib13","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.antiviral.2018.07.012","article-title":"Multiple antiviral approaches of (-)-epigallocatechin-3-gallate (EGCG) against porcine reproductive and respiratory syndrome virus infection in vitro","volume":"158","author":"Ge","year":"2018","journal-title":"Antivir. Res"},{"issue":"4","key":"10.1016\/j.vetmic.2025.110823_bib14","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3892\/etm.2024.12668","article-title":"Resveratrol suppresses melanoma growth by promoting autophagy through inhibiting the PI3K\/AKT\/mTOR signaling pathway","volume":"28","author":"Gong","year":"2024","journal-title":"Exp. Ther. Med"},{"issue":"1","key":"10.1016\/j.vetmic.2025.110823_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5582\/ddt.2015.01007","article-title":"Anti-tumor effects and cellular mechanisms of resveratrol","volume":"9","author":"Han","year":"2015","journal-title":"Drug Discov. Ther."},{"key":"10.1016\/j.vetmic.2025.110823_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2022.101470","article-title":"Ferroptosis and ferritinophagy in diabetes complications","volume":"60","author":"He","year":"2022","journal-title":"Mol. Metab."},{"issue":"3","key":"10.1016\/j.vetmic.2025.110823_bib17","doi-asserted-by":"crossref","first-page":"278","DOI":"10.3109\/08820139.2013.875039","article-title":"Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K","volume":"43","author":"Higo","year":"2014","journal-title":"Immunol. Invest"},{"key":"10.1016\/j.vetmic.2025.110823_bib18","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.redox.2017.11.004","article-title":"DUSP1 alleviates cardiac ischemia\/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways","volume":"14","author":"Jin","year":"2018","journal-title":"Redox Biol."},{"issue":"6","key":"10.1016\/j.vetmic.2025.110823_bib19","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1006\/phrs.2002.0992","article-title":"Chemopreventive effect of resveratrol, sesamol, sesame oil and sunflower oil in the Epstein-Barr virus early antigen activation assay and the mouse skin two-stage carcinogenesis","volume":"45","author":"Kapadia","year":"2002","journal-title":"Pharm. Res"},{"issue":"9","key":"10.1016\/j.vetmic.2025.110823_bib20","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.1007\/s00705-018-3847-1","article-title":"Changes to taxonomy and the international code of virus classification and nomenclature ratified by the international committee on taxonomy of viruses","volume":"163","author":"King","year":"2018","journal-title":"Arch. Virol."},{"issue":"1","key":"10.1016\/j.vetmic.2025.110823_bib21","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1002\/bab.2104","article-title":"The interplay of ROS and the PI3K\/Akt pathway in autophagy regulation","volume":"69","author":"Kma","year":"2022","journal-title":"Biotechnol. Appl. Biochem"},{"issue":"7","key":"10.1016\/j.vetmic.2025.110823_bib22","doi-asserted-by":"crossref","first-page":"3512","DOI":"10.1167\/iovs.08-2666","article-title":"Prevention of ocular inflammation in endotoxin-induced uveitis with resveratrol by inhibiting oxidative damage and nuclear factor-kappaB activation","volume":"50","author":"Kubota","year":"2009","journal-title":"Invest Ophthalmol. Vis. Sci."},{"issue":"7","key":"10.1016\/j.vetmic.2025.110823_bib23","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/s41419-023-05978-8","article-title":"Autophagy mediates an amplification loop during ferroptosis","volume":"14","author":"Lee","year":"2023","journal-title":"Cell Death Dis."},{"issue":"Pt 4","key":"10.1016\/j.vetmic.2025.110823_bib24","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1099\/vir.0.039289-0","article-title":"Identification of porcine reproductive and respiratory syndrome virus ORF1a-encoded non-structural proteins in virus-infected cells","volume":"93","author":"Li","year":"2012","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.vetmic.2025.110823_bib25","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.freeradbiomed.2023.05.004","article-title":"H1N1 influenza virus infection through NRF2-KEAP1-GCLC pathway induces ferroptosis in nasal mucosal epithelial cells","volume":"204","author":"Liu","year":"2023","journal-title":"Free Radic. Biol. Med"},{"key":"10.1016\/j.vetmic.2025.110823_bib26","article-title":"Resveratrol inhibits African swine fever virus replication by exerting antiviral and antioxidative stress activities via the Nrf2 signaling pathway","author":"Liu","year":"2025","journal-title":"Emerg. Microbes Infect."},{"issue":"8","key":"10.1016\/j.vetmic.2025.110823_bib27","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1002\/1878-0261.12936","article-title":"Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis","volume":"15","author":"Liu","year":"2021","journal-title":"Mol. Oncol."},{"key":"10.1016\/j.vetmic.2025.110823_bib28","article-title":"Quercetin alleviates postmenopausal atherosclerosis by suppressing endothelial cell ferroptosis via regulating the KEAP1\/NRF2\/GPX4 signalling pathway","author":"Lv","year":"2025","journal-title":"Br. J. Pharm."},{"issue":"13","key":"10.1016\/j.vetmic.2025.110823_bib29","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.02466-20","article-title":"Prazoles targeting Tsg101 inhibit release of epstein-barr virus following reactivation from latency","volume":"95","author":"Mannemuddhu","year":"2021","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.vetmic.2025.110823_bib30","first-page":"991","article-title":"SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors","volume":"12","author":"McGlade","year":"1992","journal-title":"Mol. Cell Biol."},{"issue":"3","key":"10.1016\/j.vetmic.2025.110823_bib31","doi-asserted-by":"crossref","first-page":"340","DOI":"10.3390\/foods9030340","article-title":"Health benefits and molecular mechanisms of resveratrol: a narrative review","volume":"9","author":"Meng","year":"2020","journal-title":"Foods"},{"issue":"4","key":"10.1016\/j.vetmic.2025.110823_bib32","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.cell.2011.10.026","article-title":"Autophagy: renovation of cells and tissues","volume":"147","author":"Mizushima","year":"2011","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.vetmic.2025.110823_bib33","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1128\/JVI.73.1.270-280.1999","article-title":"Porcine reproductive and respiratory syndrome virus comparison: divergent evolution on two continents","volume":"73","author":"Nelsen","year":"1999","journal-title":"J. Virol."},{"issue":"39","key":"10.1016\/j.vetmic.2025.110823_bib34","article-title":"The hemagglutinin of influenza a virus induces ferroptosis to facilitate viral replication","volume":"11","author":"Ouyang","year":"2024","journal-title":"Adv. Sci. (Weinh. )"},{"key":"10.1016\/j.vetmic.2025.110823_bib35","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1016\/j.biopha.2018.11.075","article-title":"Resveratrol: from enhanced biosynthesis and bioavailability to multitargeting chronic diseases","volume":"109","author":"Pannu","year":"2019","journal-title":"Biomed. Pharm."},{"issue":"13","key":"10.1016\/j.vetmic.2025.110823_bib36","doi-asserted-by":"crossref","first-page":"3197","DOI":"10.1021\/bi00064a001","article-title":"Phosphatidylinositol 3-kinase p85 SH2 domain specificity defined by direct phosphopeptide\/SH2 domain binding","volume":"32","author":"Piccione","year":"1993","journal-title":"Biochemistry"},{"key":"10.1016\/j.vetmic.2025.110823_bib37","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.virusres.2014.09.017","article-title":"Role of phosphatidylinositol-3-kinase (PI3K) and the mammalian target of rapamycin (mTOR) signalling pathways in porcine reproductive and respiratory syndrome virus (PRRSV) replication","volume":"194","author":"Pujhari","year":"2014","journal-title":"Virus Res"},{"issue":"7","key":"10.1016\/j.vetmic.2025.110823_bib38","doi-asserted-by":"crossref","first-page":"499","DOI":"10.18632\/aging.100474","article-title":"The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction","volume":"4","author":"Rasc\u00f3n","year":"2012","journal-title":"Aging (Albany NY)"},{"issue":"11","key":"10.1016\/j.vetmic.2025.110823_bib39","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.01437-24","article-title":"Tripartite motif 25 inhibits protein aggregate degradation during PRRSV infection by suppressing p62-mediated autophagy","volume":"98","author":"Ren","year":"2024","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.vetmic.2025.110823_bib40","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40813-020-00183-x","article-title":"Application of an economic calculator to determine the cost of porcine reproductive and respiratory syndrome at farm-level in 21 pig herds in Germany","volume":"7","author":"Renken","year":"2021","journal-title":"Porc. Health Manag"},{"key":"10.1016\/j.vetmic.2025.110823_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.virol.2024.110382","article-title":"Antiviral mechanism of fuzhengjiedu san against porcine reproductive and respiratory syndrome virus","volume":"603","author":"Song","year":"2025","journal-title":"Virology"},{"key":"10.1016\/j.vetmic.2025.110823_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102655","article-title":"miR-125b-5p in adipose derived stem cells exosome alleviates pulmonary microvascular endothelial cells ferroptosis via Keap1\/Nrf2\/GPX4 in sepsis lung injury","volume":"62","author":"Shen","year":"2023","journal-title":"Redox Biol."},{"key":"10.1016\/j.vetmic.2025.110823_bib43","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2024.1372330","article-title":"Regulation of ferroptosis by PI3K\/Akt signaling pathway: a promising therapeutic axis in cancer","volume":"12","author":"Su","year":"2024","journal-title":"Front Cell Dev. Biol."},{"issue":"9","key":"10.1016\/j.vetmic.2025.110823_bib44","doi-asserted-by":"crossref","first-page":"e02276","DOI":"10.1128\/JVI.02276-20","article-title":"Phosphorylation sites in the hypervariable domain in Chikungunya virus nsp3 are crucial for viral replication","volume":"95","author":"Teppor","year":"2021","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.vetmic.2025.110823_bib45","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3851\/IMP1755","article-title":"Inhibitory effects of indigowoad root polysaccharides on porcine reproductive and respiratory syndrome virus replication in vitro","volume":"16","author":"Wei","year":"2011","journal-title":"Antivir. Ther."},{"issue":"1","key":"10.1016\/j.vetmic.2025.110823_bib46","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.02370-22","article-title":"Herpes simplex virus 1-induced ferroptosis contributes to viral encephalitis","volume":"14","author":"Xu","year":"2023","journal-title":"mBio"},{"issue":"6","key":"10.1016\/j.vetmic.2025.110823_bib47","doi-asserted-by":"crossref","first-page":"806","DOI":"10.2174\/1871520614666140521121722","article-title":"From french paradox to cancer treatment: anti-cancer activities and mechanisms of resveratrol","volume":"14","author":"Yang","year":"2014","journal-title":"AntiCancer Agents Med. Chem."},{"issue":"4","key":"10.1016\/j.vetmic.2025.110823_bib48","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.00264-23","article-title":"PSMB4 degrades the porcine reproductive and respiratory syndrome virus Nsp1\u03b1 protein via the autolysosome pathway and induces the production of type I interferon","volume":"97","author":"Yi","year":"2023","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.vetmic.2025.110823_bib49","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02276-21","article-title":"EGCG restricts PRRSV proliferation by disturbing lipid metabolism","volume":"10","author":"Yu","year":"2022","journal-title":"Microbiol Spectr."},{"issue":"2","key":"10.1016\/j.vetmic.2025.110823_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbcan.2021.188591","article-title":"Multifaceted roles of HSF1 in cell death: a state-of-the-art review","volume":"1876","author":"Zhang","year":"2021","journal-title":"Biochim Biophys. Acta Rev. Cancer"},{"issue":"4","key":"10.1016\/j.vetmic.2025.110823_bib51","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s00705-010-0611-6","article-title":"A dual effect of porcine reproductive and respiratory syndrome virus replication on the phosphatidylinositol-3-kinase-dependent Akt pathway","volume":"155","author":"Zhang","year":"2010","journal-title":"Arch. Virol."},{"issue":"7","key":"10.1016\/j.vetmic.2025.110823_bib52","doi-asserted-by":"crossref","first-page":"e02209","DOI":"10.1128\/JVI.02209-17","article-title":"Two residues in NSP9 contribute to the enhanced replication and pathogenicity of highly pathogenic porcine reproductive and respiratory syndrome virus","volume":"92","author":"Zhao","year":"2018","journal-title":"J. Virol."},{"key":"10.1016\/j.vetmic.2025.110823_bib53","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9932218","article-title":"Effects and mechanisms of resveratrol on aging and age-related diseases","volume":"2021","author":"Zhou","year":"2021","journal-title":"Oxid. Med Cell Longev."},{"issue":"1","key":"10.1016\/j.vetmic.2025.110823_bib54","doi-asserted-by":"crossref","DOI":"10.1111\/jpi.12413","article-title":"Melatonin protects cardiac microvasculature against ischemia\/reperfusion injury via suppression of mitochondrial fission-VDAC1-HK2-mPTP-mitophagy axis","volume":"63","author":"Zhou","year":"2017","journal-title":"J. Pineal Res"},{"issue":"1-2","key":"10.1016\/j.vetmic.2025.110823_bib55","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.virusres.2010.07.016","article-title":"Porcine reproductive and respiratory syndrome in China","volume":"154","author":"Zhou","year":"2010","journal-title":"Virus Res"}],"container-title":["Veterinary Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113525004596?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378113525004596?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T05:40:47Z","timestamp":1773898847000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378113525004596"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":55,"alternative-id":["S0378113525004596"],"URL":"https:\/\/doi.org\/10.1016\/j.vetmic.2025.110823","relation":{},"ISSN":["0378-1135"],"issn-type":[{"value":"0378-1135","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Resveratrol can inhibit porcine reproductive and respiratory syndrome virus infection in vitro and in vivo by inhibiting PI3K\/Akt signaling pathway","name":"articletitle","label":"Article Title"},{"value":"Veterinary Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetmic.2025.110823","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110823"}}