{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:31:58Z","timestamp":1791952318992,"version":"4.3.4"},"reference-count":41,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Parasitology"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1016\/j.vetpar.2005.06.022","type":"journal-article","created":{"date-parts":[[2005,9,16]],"date-time":"2005-09-16T16:40:17Z","timestamp":1126888817000},"page":"121-130","source":"Crossref","is-referenced-by-count":46,"title":["Influence of murine Toxocara canis infection on plasma and bronchoalveolar lavage fluid eosinophil numbers and its correlation with cytokine levels"],"prefix":"10.1016","volume":"134","author":[{"given":"Ney Roner","family":"Pecinali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel N.","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio C.","family":"Amendoeira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augusto C.M. Pereira","family":"Bastos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J.Q.A.","family":"Martins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia S.","family":"Pegado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ot\u00edlio M. Pereira","family":"Bastos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia T.","family":"Bozza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo C.","family":"Castro-Faria-Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetpar.2005.06.022_bib1","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1097\/00007611-199809000-00019","article-title":"Visceral larva migrans and the hypereosinophilia syndrome","volume":"91","author":"Arango","year":"1998","journal-title":"S. Med. J."},{"key":"10.1016\/j.vetpar.2005.06.022_bib2","series-title":"Bulletin de la Soci\u00e9t\u00e9 de Pathologie Exotique","article-title":"Toxocarosis (visceral larva migrans) in relation to tropical eosinophilia","author":"Beaver","year":"1952"},{"key":"10.1016\/j.vetpar.2005.06.022_bib3","series-title":"Fisiologia","article-title":"Microcircula\u00e7\u00e3o e Linfaticos","author":"Berne","year":"2000"},{"key":"10.1016\/j.vetpar.2005.06.022_bib4","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4269\/ajtmh.1987.36.75","article-title":"Circulating excretory\u2013secretory antigen levels and specific antibody responses in mice infected with Toxocara canis","volume":"36","author":"Bowman","year":"1987","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.vetpar.2005.06.022_bib5","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1097\/01.shk.0000140305.01641.c8","article-title":"Macrophage migration inhibitory factor levels correlate with fatal outcome in sepsis","volume":"22","author":"Bozza","year":"2004","journal-title":"Shock"},{"key":"10.1016\/j.vetpar.2005.06.022_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-3024.1994.tb00297.x","article-title":"Toxocara canis-induced murine pulmonary inflammation: analysis of cells and proteins in lung tissue and bronchoalveolar lavage fluid","volume":"16","author":"Buijs","year":"1994","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib7","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1017\/S0022149X00014723","article-title":"The use of 35S-labelled Toxocara canis to determine larval numbers in tissues","volume":"66","author":"Carter","year":"1992","journal-title":"J. Helminthol."},{"issue":"Suppl. 2","key":"10.1016\/j.vetpar.2005.06.022_bib8","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1590\/S0074-02761997000800024","article-title":"The role of the eosinophil-selective chemokine, eotaxin, in allergic and non-allergic airways inflammation","volume":"92","author":"Conroy","year":"1997","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"10.1016\/j.vetpar.2005.06.022_bib9","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1096\/fasebj.9.1.7821763","article-title":"Preferential expression of CD30 by human CD4+ T cells producing Th2-type cytokines","volume":"9","author":"Del Prete","year":"1995","journal-title":"FASEB J."},{"key":"10.1016\/j.vetpar.2005.06.022_bib10","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1172\/JCI115300","article-title":"Purified protein derivative of Mycobacterium tuberculosis and excretory\u2013secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production","volume":"88","author":"Del Prete","year":"1991","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.vetpar.2005.06.022_bib11","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1128\/IAI.67.2.989-993.1999","article-title":"Interleukin-5 transgenic mice show enhanced resistance to primary infections with Nippostrongylus brasiliensis but not primary infections with Toxocara canis","volume":"67","author":"Dent","year":"1999","journal-title":"Infect. Immun."},{"issue":"Suppl. 2","key":"10.1016\/j.vetpar.2005.06.022_bib12","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1590\/S0074-02761997000800015","article-title":"Cytokines in the modulation of eosinophilia","volume":"92","author":"Faccioli","year":"1997","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"10.1016\/j.vetpar.2005.06.022_bib13","first-page":"173","article-title":"Estudio comparativo de la influencia de la luz en el embrionamento experimental de los huevos de Toxocara canis y Toxocara leonine","author":"Fenoy","year":"1987","journal-title":"Rev. Iber. Parasitol. Extraordin\u00e1rio"},{"key":"10.1016\/j.vetpar.2005.06.022_bib14","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/S0952-7915(99)80014-4","article-title":"Antigen presentation by MHC class I and its regulation by interferon gamma","volume":"11","author":"Fruh","year":"1999","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib15","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S1081-1206(10)62403-9","article-title":"Are chemokines essential or secondary participants in allergic responses?","volume":"84","author":"Gangur","year":"2000","journal-title":"Ann. Allergy Asthma Immunol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib16","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1086\/315214","article-title":"Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options","volume":"181","author":"Gogos","year":"2000","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.vetpar.2005.06.022_bib17","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/S0020-7519(99)00007-7","article-title":"Visceral larva migrans: migratory pattern of Toxocara canis in pigs","volume":"29","author":"Helwigh","year":"1999","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib18","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1159\/000058667","article-title":"Human toxocariasis and the visceral larva migrans syndrome: correlative immunopathology","volume":"66","author":"Kayes","year":"1997","journal-title":"Chem. Immunol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib19","doi-asserted-by":"crossref","first-page":"2132","DOI":"10.1128\/IAI.55.9.2132-2136.1987","article-title":"Use of bronchoalveolar lavage to compare local pulmonary immunity with the systemic immune response of Toxocara canis-infected mice","volume":"55","author":"Kayes","year":"1987","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetpar.2005.06.022_bib20","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0014-4894(80)90055-7","article-title":"Toxocara canis: T lymphocyte function in murine visceral larva migrans and eosinophilia onset","volume":"49","author":"Kayes","year":"1980","journal-title":"Exp. Parasitol."},{"issue":"Suppl. 1","key":"10.1016\/j.vetpar.2005.06.022_bib21","doi-asserted-by":"crossref","first-page":"S124","DOI":"10.1007\/s001340051129","article-title":"Immunomodulatory therapies in sepsis","volume":"26","author":"Kox","year":"2000","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.vetpar.2005.06.022_bib22","first-page":"461","article-title":"Mechanisms of eosinophilia in BALB\/c-nu\/+ and congenitally athymic BALB\/c-nu\/nu mice infected with Toxocara canis","volume":"84","author":"Kusama","year":"1995","journal-title":"Immunology"},{"key":"10.1016\/j.vetpar.2005.06.022_bib23","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1111\/j.1398-9995.2004.00469.x","article-title":"Cytokine-regulated accumulation of eosinophils in inflammatory disease","volume":"59","author":"Lampinen","year":"2004","journal-title":"Allergy"},{"key":"10.1016\/j.vetpar.2005.06.022_bib24","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0169-4758(99)01607-5","article-title":"Do eosinophils have a role in the killing of helminth parasites?","volume":"16","author":"Meeusen","year":"2000","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.vetpar.2005.06.022_bib25","first-page":"84","article-title":"Eosinophilia","volume":"23","author":"Mendes","year":"2000","journal-title":"Rev. Bras. Alerg. Immunopathol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib26","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.coph.2004.03.005","article-title":"Inhibition of IL-6 for the treatment of inflammatory diseases","volume":"4","author":"Nishimoto","year":"2004","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib27","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1006\/clin.1996.0037","article-title":"Eosinophil chemotactic activity in bronchoalveolar lavage fluid obtained from Toxocara canis-infected rats","volume":"78","author":"Okada","year":"1996","journal-title":"Clin. Immunol. Immunopathol."},{"issue":"Suppl. 2","key":"10.1016\/j.vetpar.2005.06.022_bib28","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1590\/S0074-02761997000800013","article-title":"The enigmatic eosinophil: investigation of the biological role of eosinophils in parasitic helminth infection","volume":"92","author":"Ovington","year":"1997","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"10.1016\/j.vetpar.2005.06.022_bib29","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/j.1365-3024.1993.tb00637.x","article-title":"Antibody to interleukin 5 prevents blood and tissue eosinophilia but not liver trapping in murine larval toxocariasis","volume":"15","author":"Parsons","year":"1993","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib30","doi-asserted-by":"crossref","first-page":"529","DOI":"10.2307\/3282834","article-title":"Kinetics of liver trapping of infective larvae in murine toxocariasis","volume":"76","author":"Parsons","year":"1990","journal-title":"J. Parasitol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib31","first-page":"153","article-title":"Eosinophilia, granuloma formation, migratory behaviour of second stage larvae in murine Toxocara canis infection. Effect of the inoculum size","volume":"31","author":"Piergili Fioretti","year":"1989","journal-title":"Parassitologia"},{"key":"10.1016\/j.vetpar.2005.06.022_bib32","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1378\/chest.102.1.294","article-title":"Acute eosinophilic pneumonia due to toxocariasis with bronchoalveolar lavage findings","volume":"102","author":"Roig","year":"1992","journal-title":"Chest"},{"key":"10.1016\/j.vetpar.2005.06.022_bib33","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1056\/NEJM199805283382206","article-title":"Eosinophilia","volume":"338","author":"Rothenberg","year":"1998","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.vetpar.2005.06.022_bib34","first-page":"H1428","article-title":"Development and characterization of a model of eosinophil-mediated cardiomyopathy in rats infected with Toxocara canis","volume":"262","author":"Schaffer","year":"1992","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib35","first-page":"571","article-title":"Ascaridos de Perros y Gatos: un problema de salud publica y de medicina veterinaria","volume":"94","author":"Schantz","year":"1983","journal-title":"Bol. Sanit. Panam."},{"key":"10.1016\/j.vetpar.2005.06.022_bib36","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1365-3024.1984.tb00812.x","article-title":"Interrelationship of eosinophilia and IgE antibody production to larval ES antigen in Toxocara canis infected mice","volume":"6","author":"Sugane","year":"1984","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib37","first-page":"285","article-title":"Occurrence of interleukin-5 production by CD4\u2013CD8- (double-negative) T cells in lungs of both normal and congenitally athymic nude mice infected with Toxocara canis","volume":"85","author":"Takamoto","year":"1995","journal-title":"Immunology"},{"key":"10.1016\/j.vetpar.2005.06.022_bib38","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1365-3024.1993.tb00636.x","article-title":"Mechanisms of eosinophilia in Toxocara canis infected mice: in vitro production of interleukin 5 by lung cells of both normal and congenitally athymic nude mice","volume":"15","author":"Takamoto","year":"1993","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib39","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0167-5699(00)01634-0","article-title":"CCL chemokines and asthma","volume":"21","author":"Teran","year":"2000","journal-title":"Immunol. Today"},{"key":"10.1016\/j.vetpar.2005.06.022_bib40","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1023\/A:1020502516196","article-title":"Molecular regulation of cytokine gene expression during the immune response","volume":"19","author":"Viola","year":"1999","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.vetpar.2005.06.022_bib41","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1159\/000024038","article-title":"Expression of Th1 and Th2 immunoregulatory cytokines by human eosinophils","volume":"118","author":"Woerly","year":"1999","journal-title":"Int. Arch. Allergy Immunol."}],"container-title":["Veterinary Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401705003511?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401705003511?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T15:18:13Z","timestamp":1586445493000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304401705003511"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":41,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S0304401705003511"],"URL":"https:\/\/doi.org\/10.1016\/j.vetpar.2005.06.022","relation":{},"ISSN":["0304-4017"],"issn-type":[{"value":"0304-4017","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]}}}