{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T00:22:28Z","timestamp":1768263748202,"version":"3.49.0"},"reference-count":13,"publisher":"Elsevier BV","issue":"3-4","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Parasitology"],"published-print":{"date-parts":[[2008,8]]},"DOI":"10.1016\/j.vetpar.2008.04.027","type":"journal-article","created":{"date-parts":[[2008,5,22]],"date-time":"2008-05-22T08:53:21Z","timestamp":1211446401000},"page":"242-248","source":"Crossref","is-referenced-by-count":18,"title":["Computed tomography (CT) observation of pulmonary emboli caused by long-term administration of ivermectin in dogs experimentally infected with heartworms"],"prefix":"10.1016","volume":"155","author":[{"given":"Ayuto","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazutaka","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miori","family":"Kishimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichiro","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryuichiro","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetpar.2008.04.027_bib1","unstructured":"American Heartworm Society, 2005. 2005 guidelines for the diagnosis, prevention and management of heartworm (Dirofilaria immitis) infection in dogs. Vet. Parasitol. 133, 255\u2013266."},{"key":"10.1016\/j.vetpar.2008.04.027_bib2","first-page":"310","article-title":"Is there a better way to administer heartworm adulticidal therapy?","volume":"98","author":"Atkins","year":"2003","journal-title":"Vet. Med."},{"key":"10.1016\/j.vetpar.2008.04.027_bib3","series-title":"Recent Advances in Heartworm Disease: Symposium\u201998","first-page":"193","article-title":"The effect of chronic administration of milbemycin oxime and ivermectin on microfilaremias in heartworm-infected dogs","author":"Courtney","year":"1998"},{"key":"10.1016\/j.vetpar.2008.04.027_bib4","series-title":"Recent Advances in Heartworm Disease: Symposium\u201998","first-page":"225","article-title":"Influence of exercise on recovery of dogs following heartworm adulticidal treatment with melarsomine","author":"Fukami","year":"1998"},{"key":"10.1016\/j.vetpar.2008.04.027_bib5","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1292\/jvms1939.50.723","article-title":"Clinical effects after heartworm removal from pulmonary arteries using flexible alligator forceps in dogs with common dirofilariasis","volume":"50","author":"Ishihara","year":"1988","journal-title":"Nippon Juigaku Zasshi"},{"key":"10.1016\/j.vetpar.2008.04.027_bib6","series-title":"Proceedings of the Heartworm Symposium\u201980","first-page":"15","article-title":"Lower dose of ivermectin as a microfilaricide, 0.05mg\/kg","author":"Jackson","year":"1986"},{"key":"10.1016\/j.vetpar.2008.04.027_bib7","first-page":"405","article-title":"Alternative treatment of heartworm disease","volume":"4","author":"Kato","year":"1992","journal-title":"Probl. Vet. Med."},{"key":"10.1016\/j.vetpar.2008.04.027_bib8","unstructured":"McCall, J.W., 2003. Heartworm-positive dog requires tailored treatment. DVM Best Practices (March Issue on Parasite Control), 16\u201321."},{"key":"10.1016\/j.vetpar.2008.04.027_bib9","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.vetpar.2005.04.005","article-title":"The safety-net story about macrocyclic lactone heartworm preventives: a review, an update, and recommendations","volume":"133","author":"McCall","year":"2005","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2008.04.027_bib10","series-title":"Recent Advances in Heartworm Disease: Symposium\u201998","first-page":"209","article-title":"Heartworm adulticidal activity of prophylactic doses of IVM (6\u03bcg\/kg) plus pyrantel administered monthly to dogs","author":"McCall","year":"1998"},{"key":"10.1016\/j.vetpar.2008.04.027_bib11","series-title":"Recent Advances in Heartworm Disease: Symposium\u201901","first-page":"189","article-title":"Further evidence of clinical prophylactic, retro-active (reach-back) and adulticidal activity of monthly administrations of IVM (Heartgard Plus\u2122) in dogs experimentally infected with heartworms","author":"McCall","year":"2001"},{"key":"10.1016\/j.vetpar.2008.04.027_bib12","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2307\/3276912","article-title":"Longevity of an experimental infection with Dirofilaria immitis in a dog","volume":"54","author":"Newton","year":"1968","journal-title":"J. Parasitol."},{"key":"10.1016\/j.vetpar.2008.04.027_bib13","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.vetpar.2004.06.024","article-title":"Efficacy of long-term monthly administration of IVM on the progress of naturally acquired heartworm infection in dogs","volume":"124","author":"Venco","year":"2004","journal-title":"Vet. Parasitol."}],"container-title":["Veterinary Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401708002549?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401708002549?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T07:21:10Z","timestamp":1545981670000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304401708002549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":13,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["S0304401708002549"],"URL":"https:\/\/doi.org\/10.1016\/j.vetpar.2008.04.027","relation":{},"ISSN":["0304-4017"],"issn-type":[{"value":"0304-4017","type":"print"}],"subject":[],"published":{"date-parts":[[2008,8]]}}}