{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T05:10:15Z","timestamp":1781154615232,"version":"3.54.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"3-4","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Parasitology"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1016\/j.vetpar.2008.11.015","type":"journal-article","created":{"date-parts":[[2008,12,3]],"date-time":"2008-12-03T18:46:24Z","timestamp":1228329984000},"page":"242-250","source":"Crossref","is-referenced-by-count":42,"title":["The immune response in Taenia solium neurocysticercosis in pigs is associated with astrogliosis, axonal degeneration and altered blood\u2013brain barrier permeability"],"prefix":"10.1016","volume":"160","author":[{"given":"C.S.","family":"Sikasunge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.V.","family":"Johansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.K.","family":"Phiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"A.L.","family":"Willingham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.S.","family":"Leifsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetpar.2008.11.015_bib1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0304-4017(97)00059-9","article-title":"Taenia solium cysticercosis in young pigs: age at first infection and histological characteristics","volume":"76","author":"Aluja","year":"1998","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib2","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1053\/jcpa.2002.0579","article-title":"Granuloma formation and parasite disintegration in porcine cysticercosis: comparison with human neurocysticercosis","volume":"127","author":"Alvarez","year":"2002","journal-title":"J. Comp. Pathol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jneuroim.2005.11.020","article-title":"Breakdown of the blood\u2013brain barrier and blood\u2013cerebrospinal fluid barrier is associated with differential leukocyte migration in distinct compartments of the CNS during the course of murine NCC","volume":"173","author":"Alvarez","year":"2006","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib4","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0165-5728(02)00101-7","article-title":"The human nervous tissue in proximity to granulomatous lesions induced by Taenia solium metacestodes displays an active response","volume":"127","author":"Alvarez","year":"2002","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib5","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1023\/A:1006995624754","article-title":"Suramin disrupts the gliotic response following a stab wound injury to the adult rat brain","volume":"27","author":"Di Prospero","year":"1998","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib6","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0304-4017(86)90094-4","article-title":"Host\u2013parasite relationship in cysticercosis: immunologic study in different compartments of the host","volume":"20","author":"Flisser","year":"1986","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib7","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/S0165-0173(01)00102-3","article-title":"Molecular and cellular permeability control at the blood\u2013brain barrier","volume":"36","author":"Gloor","year":"2001","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.vetpar.2008.11.015_bib8","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.jcpa.2007.02.006","article-title":"Hepatic changes in congenital Schistosoma japonicum infections in pigs","volume":"136","author":"Iburg","year":"2007","journal-title":"J. Comp. Pathol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib9","doi-asserted-by":"crossref","first-page":"94","DOI":"10.4269\/ajtmh.1999.60.94","article-title":"Detection of light subunit neurofilament and glial fibrillary acidic protein in cerebrospinal fluid of Trypanosoma brucei gambiense-infected patients","volume":"60","author":"Lejon","year":"1999","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.vetpar.2008.11.015_bib10","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0304-4017(02)00290-X","article-title":"The inflammatory cell infiltrates in porcine cysticercosis: immunohistochemical analysis during various stages of infection","volume":"109","author":"Londo\u00f1o","year":"2002","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib11","series-title":"Manual of the Histologic Methods of the Armed Forces Institute of Pathology","year":"1960"},{"key":"10.1016\/j.vetpar.2008.11.015_bib12","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1006\/expr.2000.4490","article-title":"Taenia solium: a cysteine protease secreted by metacestodes depletes human CD4 lymphocytes in vitro","volume":"94","author":"Molinari","year":"2000","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib13","doi-asserted-by":"crossref","first-page":"502","DOI":"10.4269\/ajtmh.1993.49.502","article-title":"Immunization against porcine cysticercosis in an endemic area in Mexico: a field and laboratory study","volume":"49","author":"Molinari","year":"1993","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.vetpar.2008.11.015_bib14","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1369\/jhc.3A6213.2004","article-title":"Differential expression of apolipoprotein D in human astroglial and oligodendroglial cells","volume":"52","author":"Navarro","year":"2004","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.vetpar.2008.11.015_bib15","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1007\/s00436-001-0510-6","article-title":"Taenia solium cysticercosis: lymphocytes in the inflammatory reaction in naturally infected pigs","volume":"88","author":"P\u00e9rez-Torres","year":"2002","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2008.11.015_bib16","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1079\/JOH2005314","article-title":"Assessment of routine inspection methods for porcine cysticercosis in Zambian village pigs","volume":"80","author":"Phiri","year":"2006","journal-title":"J. Helminthol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib17","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s00436-003-0850-5","article-title":"Detection of glial fibrillary acidic protein and neurofilaments in the cerebrospinal fluid of patients with neurocysticercosis","volume":"90","author":"Quintanar","year":"2003","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2008.11.015_bib18","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0022-510X(95)00152-R","article-title":"Glial fibrillary acidic protein in CSF of multiple sclerosis patients: relation to neurological deficit","volume":"133","author":"Rosengren","year":"1995","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.vetpar.2008.11.015_bib19","doi-asserted-by":"crossref","first-page":"4554","DOI":"10.1128\/IAI.69.7.4554-4560.2001","article-title":"Brain granulomas in neurocysticercosis patients are associated with a Th1 and Th2 profile","volume":"69","author":"Restrepo","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetpar.2008.11.015_bib20","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0165-5728(98)00112-X","article-title":"Analysis of immune lesions in neurocysticercosis patients: central nervous system response to helminth appears Th1-like instead of Th2","volume":"89","author":"Restrepo","year":"1998","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib21","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1111\/j.1365-3156.2008.02059.x","article-title":"Human and porcine neurocysticercosis: differences in the distribution and developmental stages of cysticerci","volume":"13","author":"S\u00e1enz","year":"2008","journal-title":"Trop. Med. Int. Health"},{"key":"10.1016\/j.vetpar.2008.11.015_bib22","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1017\/S0031182008004678","article-title":"Host-cell apoptosis in Taenia solium induced brain granulomas in naturally infected pigs","volume":"135","author":"Sikasunge","year":"2008","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2008.11.015_bib23","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.vetpar.2006.03.006","article-title":"Lymphocyte apoptosis in the inflammatory reaction around Taenia solium metacestodes in porcine cysticercosis","volume":"140","author":"Solano","year":"2006","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2008.11.015_bib24","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/BF00937107","article-title":"Suppression of murine lymphocyte proliferation induced by a small RNA-peptide from the Taenia solium metacestode","volume":"81","author":"Tato","year":"1995","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2008.11.015_bib25","first-page":"267","article-title":"Glial fibrillary acidic protein in the cerebrospinal fluid of patients with dementia","volume":"7","author":"Wallin","year":"1996","journal-title":"Dementia"},{"key":"10.1016\/j.vetpar.2008.11.015_bib26","first-page":"185","article-title":"Host\u2013parasite interactions in Taenia solium cysticercosis","volume":"1","author":"White","year":"1992","journal-title":"Infect. Agents Dis."}],"container-title":["Veterinary Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401708006584?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401708006584?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,3,4]],"date-time":"2024-03-04T03:09:38Z","timestamp":1709521778000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304401708006584"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":26,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["S0304401708006584"],"URL":"https:\/\/doi.org\/10.1016\/j.vetpar.2008.11.015","relation":{},"ISSN":["0304-4017"],"issn-type":[{"value":"0304-4017","type":"print"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}