{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T14:32:01Z","timestamp":1789914721204,"version":"4.0.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Parasitology"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1016\/j.vetpar.2009.02.012","type":"journal-article","created":{"date-parts":[[2009,2,15]],"date-time":"2009-02-15T11:09:02Z","timestamp":1234696142000},"page":"7-15","source":"Crossref","is-referenced-by-count":85,"title":["Systemic inflammatory responses in dogs experimentally infected with Babesia canis; a haematological study"],"prefix":"10.1016","volume":"162","author":[{"given":"Th.P.M.","family":"Schetters","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.G.M.","family":"Kleuskens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Van De Crommert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.W.J.","family":"De Leeuw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.-L.","family":"Finizio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Gorenflot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetpar.2009.02.012_bib1","first-page":"95","article-title":"Nombre de plaquettes et volume moyen plaquettaire dans la b\u00e1besiose du chien","volume":"156","author":"Baric Rafaj","year":"2005","journal-title":"Rev. Med. Vet."},{"key":"10.1016\/j.vetpar.2009.02.012_bib2","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.vetpar.2006.05.002","article-title":"Central and peripheral Babesia canis rossi parasitaemias and their association with outcome of infection","volume":"141","author":"B\u0151hm","year":"2006","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib3","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.vetpar.2006.01.046","article-title":"Canine babesiosis in France","volume":"138","author":"Bourdoiseau","year":"2006","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib4","doi-asserted-by":"crossref","first-page":"94","DOI":"10.2460\/javma.1994.204.01.94","article-title":"Hypotensive shock syndrome associated with acute Babesia canis infection in a dog","volume":"204","author":"Freeman","year":"1994","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.1016\/j.vetpar.2009.02.012_bib5","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.vetpar.2005.07.016","article-title":"Clinicopathological findings in naturally occurring cases of babesiosis caused by large Babesia from dogs of northeastern Italy","volume":"134","author":"Furlanello","year":"2005","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib6","first-page":"1","article-title":"Syndrome disseminierter intravasaler Geriennung (Verbrauchscoagulopathie) bei Haustieren","volume":"24","author":"Hoffmann","year":"1976","journal-title":"Fortschr. Veterinarmed."},{"key":"10.1016\/j.vetpar.2009.02.012_bib7","doi-asserted-by":"crossref","first-page":"14","DOI":"10.4102\/jsava.v71i1.670","article-title":"Blood pressure changes in dogs with babesiosis","volume":"71","author":"Jacobson","year":"2000","journal-title":"J. S. Afr. Vet. Assoc."},{"key":"10.1016\/j.vetpar.2009.02.012_bib8","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.vetpar.2006.01.047","article-title":"The South African form of severe and complicated canine babesiosis: clinical advances 1994\u20132004","volume":"138","author":"Jacobson","year":"2006","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib9","doi-asserted-by":"crossref","first-page":"63","DOI":"10.4102\/jsava.v74i3.512","article-title":"Thrombocytopaenia in canine babesiosis and its clinical usefulness","volume":"74","author":"Kettner","year":"2003","journal-title":"J. S. Afr. Vet. Assoc."},{"key":"10.1016\/j.vetpar.2009.02.012_bib10","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0165-2478(90)90117-9","article-title":"Tumour necrosis factor, fever and fatality in falciparum malaria","volume":"25","author":"Kwiatkowski","year":"1990","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.vetpar.2009.02.012_bib11","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1556\/AVet.54.2006.3.7","article-title":"Clinical manifestations of canine babesiosis in Hungary (63 cases)","volume":"54","author":"M\u00e1th\u00e9","year":"2006","journal-title":"Acta Vet. Hung."},{"key":"10.1016\/j.vetpar.2009.02.012_bib12","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.vetpar.2006.10.004","article-title":"Evidence of an acute phase response in dogs naturally infected with Babesia canis","volume":"144","author":"Matijatko","year":"2007","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib13","first-page":"1067","article-title":"Hemostatic disorders during the course of canine babesiosis","volume":"60","author":"Milczak","year":"2004","journal-title":"Med. Weter."},{"key":"10.1016\/j.vetpar.2009.02.012_bib14","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1161\/01.RES.1.4.354","article-title":"The variable arterial pressure response to serotonin in laboratory animals and man","volume":"1","author":"Page","year":"1953","journal-title":"Circ. Res."},{"key":"10.1016\/j.vetpar.2009.02.012_bib15","first-page":"389","article-title":"Description clinique, h\u00e9matologique et s\u00e9rologique de 133 cas de bab\u00e9siose canine","volume":"21","author":"Pag\u00e8s","year":"1986","journal-title":"Prat. M\u00e9d. Chir. An. Comp."},{"key":"10.1016\/j.vetpar.2009.02.012_bib16","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1080\/00034989859474","article-title":"Canine babesiosis in South Africa: more than one disease. Does this serve as a model for falciparum malaria?","volume":"92","author":"Reyers","year":"1998","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib17","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.tvjl.2006.05.017","article-title":"Clinico-pathological findings and coagulation disorders in 45 cases of canine babesiosis in Spain","volume":"174","author":"Ruiz de Gopegui","year":"2007","journal-title":"Vet. J."},{"key":"10.1016\/j.vetpar.2009.02.012_bib18","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0304-4017(94)90114-7","article-title":"Vaccination of dogs against Babesia canis infection using antigen from culture supernatant with an emphasis on clinical babesiosis","volume":"52","author":"Schetters","year":"1994","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib19","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/j.1365-3024.1995.tb00891.x","article-title":"Strain variation limits protective activity of vaccines based on soluble Babesia canis antigens","volume":"17","author":"Schetters","year":"1995","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1365-3024.1996.d01-1.x","article-title":"Not peripheral parasitaemia but the level of soluble parasite antigen in plasma correlates with vaccine efficacy against Babesia canis","volume":"18","author":"Schetters","year":"1996","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib21","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1017\/S0031182097001686","article-title":"Different Babesia canis isolates, different diseases","volume":"115","author":"Schetters","year":"1997","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2009.02.012_bib22","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0304-4017(97)00044-7","article-title":"Vaccination of dogs against Babesia canis","volume":"73","author":"Schetters","year":"1997","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib23","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1080\/00034989859483","article-title":"Parasite localisation and dissemination in the Babesia-infected host","volume":"92","author":"Schetters","year":"1998","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib24","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.vetpar.2007.06.010","article-title":"Endocrine predictors of mortality in canine babesiosis caused by Babesia canis rossi","volume":"148","author":"Schoeman","year":"2007","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib25","first-page":"345","article-title":"Shock\u2014a short review","volume":"47","author":"Sethi","year":"2003","journal-title":"Indian J. Anaesth."},{"key":"10.1016\/j.vetpar.2009.02.012_bib26","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.vetpar.2008.07.024","article-title":"Babesia canis canis and Babesia canis vogeli clinicopathological findings and DNA detection by means of PCR-RFLP in blood from Italian dogs suspected of tick-borne disease","volume":"157","author":"Solano-Gallego","year":"2008","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib27","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1939-165X.2005.tb00028.x","article-title":"Serum concentration of some acute phase proteins in naturally occurring canine babesiosis: a preliminary study","volume":"34","author":"Ulutas","year":"2005","journal-title":"Vet. Clin. Pathol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib28","first-page":"174","article-title":"Haematological and biochemical profile in experimental canine babesiosis (Babesia canis)","volume":"66","author":"Vercammen","year":"1997","journal-title":"Vlaams Diergeneeskundig Tijdschrift"},{"key":"10.1016\/j.vetpar.2009.02.012_bib29","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1161\/01.RES.57.2.262","article-title":"Acute hypotension due to platelet serotonin-induced chemorelaxes after intravenous injection of dextran sulfate in the rabbit","volume":"57","author":"Wiggins","year":"1985","journal-title":"Circ. Res."},{"key":"10.1016\/j.vetpar.2009.02.012_bib30","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1046\/j.1365-2249.1996.07699.x","article-title":"A malaria parasite toxin associated with Plasmodium vivax paroxysms","volume":"104","author":"Wijesekera","year":"1996","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.vetpar.2009.02.012_bib31","series-title":"Babesiosis of Domestic Animals and Man","first-page":"99","article-title":"Pathogenesis of babesiosis","author":"Wright","year":"1988"},{"key":"10.1016\/j.vetpar.2009.02.012_bib32","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.vetpar.2006.11.008","article-title":"Hematological changes during the course of canine babesiosis by large Babesia in domestic dogs in Warsaw (Poland)","volume":"145","author":"Zygner","year":"2007","journal-title":"Vet. Parasitol."}],"container-title":["Veterinary Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401709001137?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401709001137?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,3,10]],"date-time":"2024-03-10T15:35:57Z","timestamp":1710084957000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304401709001137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":32,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["S0304401709001137"],"URL":"https:\/\/doi.org\/10.1016\/j.vetpar.2009.02.012","relation":{},"ISSN":["0304-4017"],"issn-type":[{"value":"0304-4017","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}