{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T16:52:02Z","timestamp":1761929522970,"version":"3.38.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"crossref","award":["FOOD-CT-200X-023025"],"award-info":[{"award-number":["FOOD-CT-200X-023025"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Parasitology"],"published-print":{"date-parts":[[2011,4]]},"DOI":"10.1016\/j.vetpar.2010.11.032","type":"journal-article","created":{"date-parts":[[2010,11,26]],"date-time":"2010-11-26T09:13:03Z","timestamp":1290762783000},"page":"79-89","source":"Crossref","is-referenced-by-count":17,"title":["Disruption of egg formation by Fasciola hepatica following treatment in vivo with triclabendazole in the sheep host"],"prefix":"10.1016","volume":"177","author":[{"given":"E.","family":"Toner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.P.","family":"Brennan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.E.B.","family":"Hanna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.W.J.","family":"Edgar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Fairweather","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetpar.2010.11.032_bib0005","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0304-4017(97)00197-0","article-title":"Embryonation and infectivity of Ascaris suum eggs isolated from worms expelled by pigs treated with albendazole, pyrantel pamoate, ivermectin or piperazine dihydrochloride","volume":"75","author":"Boes","year":"1998","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0010","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1136\/vr.120.19.460","article-title":"Extension of the prepatent period of Fasciola hepatica in infected animals following treatment with triclabendazole","volume":"120","author":"B\u00fcscher","year":"1987","journal-title":"Vet. Rec."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0015","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1017\/S0031182098002662","article-title":"Observations on the mechanism of eggshell formation in the liver fluke, Fasciola hepatica","volume":"116","author":"Colhoun","year":"1998","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2010.11.032_bib0020","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1038\/209424a0","article-title":"Some apparent effects of bithionol (\u201cActamer\u201d) on Fasciola hepatica","volume":"209","author":"Dawes","year":"1966","journal-title":"Nature"},{"key":"10.1016\/j.vetpar.2010.11.032_bib0025","first-page":"297","article-title":"Experimental fascioliasis: some effects on Fasciola hepatica of treatment of rat hosts with bithionol (\u201cActamer\u201d)","volume":"7","author":"Dawes","year":"1966","journal-title":"Helminthologia"},{"key":"10.1016\/j.vetpar.2010.11.032_bib0030","first-page":"97","article-title":"Experimental fascioliasis in small mammals: apparent effects of bithionol on Fasciola hepatica in rats","volume":"8","author":"Dawes","year":"1967","journal-title":"Helminthologia"},{"key":"10.1016\/j.vetpar.2010.11.032_bib0035","first-page":"575","article-title":"Further evidence on the effect of bithionol (\u201cActamer\u201d) on Fasciola hepatica","volume":"14","author":"Dawes","year":"1968","journal-title":"Wiad. Parazytol."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0040","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/0020-7519(88)90076-8","article-title":"Fasciola hepatica: morphological changes in vitelline cells following treatment in vitro with the deacetylated (amine) metabolite of diamphenethide (DAMD)","volume":"18","author":"Fairweather","year":"1988","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0045","series-title":"Fasciolosis","first-page":"47","article-title":"Development of Fasciola hepatica in the mammalian host","author":"Fairweather","year":"1999"},{"key":"10.1016\/j.vetpar.2010.11.032_bib0050","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.vetpar.2006.06.025","article-title":"The effect of a parenteral ivermectin\/closantel injection on the growth and reproductive development of early immature Fasciola hepatica in cattle","volume":"142","author":"Hanna","year":"2006","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0055","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.vetpar.2008.07.022","article-title":"Fasciola hepatica: histology of the testis in egg-producing adults of several laboratory-maintained isolates of flukes grown to maturity in cattle and sheep and in flukes from naturally infected hosts","volume":"157","author":"Hanna","year":"2008","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0060","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.vetpar.2009.11.014","article-title":"Fasciola hepatica: histological changes in the reproductive structures of triclabendazole (TCBZ)-sensitive and TCBZ-resistant flukes after treatment in vivo with TCBZ and the related benzimidazole derivative, Compound Alpha","volume":"168","author":"Hanna","year":"2010","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0065","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1751-0813.1969.tb05012.x","article-title":"Quantitative diagnosis of chronic fasciolosis - 2. The estimation of daily total egg production of Fasciola hepatica and the number of adult flukes in sheep by faecal egg counts","volume":"45","author":"Happich","year":"1969","journal-title":"Aust. Vet. J."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0070","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0304-4017(82)90105-4","article-title":"Morphological changes in trichostrongylid eggs after treatment with fenbendazole","volume":"11","author":"Kirsch","year":"1982","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0075","first-page":"1853","article-title":"Reduced reproductive potential of Fasciola hepatica surviving in cattle treated with albendazole","volume":"75","author":"Lang","year":"1980","journal-title":"Vet. Med. Small Anim. Clin."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0080","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/S0007-1935(17)40004-2","article-title":"4-Cyano-2-iodo-6-nitrophenol, M&B 10,775. I. Activity against experimental fascioliasis in rabbits, sheep and calves","volume":"123","author":"Lucas","year":"1967","journal-title":"Br. Vet. J."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0085","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0034-5288(18)30845-2","article-title":"Flukicidal action of closantel against immature and mature Fasciola hepatica in experimentally infected rats and sheep","volume":"44","author":"Maes","year":"1988","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0090","first-page":"450","article-title":"Comparative efficacy of closantel and triclabendazole against Fasciola hepatica in experimentally infected sheep","volume":"127","author":"Maes","year":"1990","journal-title":"Vet. Rec."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0095","doi-asserted-by":"crossref","first-page":"879","DOI":"10.2460\/ajvr.1982.43.05.879","article-title":"Efficacy of albendazole for treatment of naturally acquired Fasciola hepatica in calves","volume":"43","author":"Malone","year":"1982","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0100","doi-asserted-by":"crossref","first-page":"851","DOI":"10.2460\/ajvr.1984.45.05.851","article-title":"Efficacy of clorsulon for treatment of mature naturally acquired and 8-week-old experimentally induced Fasciola hepatica infections in cattle","volume":"45","author":"Malone","year":"1984","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0105","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.vetpar.2009.02.004","article-title":"An evaluation of the efficacy of compound alpha and triclabendazole against two isolates of Fasciola hepatica","volume":"162","author":"McConville","year":"2009","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0110","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s00436-009-1649-9","article-title":"Fasciola hepatica: disruption of spermatogenesis by the fasciolicide compound alpha","volume":"106","author":"McConville","year":"2009","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0115","first-page":"399","article-title":"Triclabendazole-resistant liver fluke in Scottish sheep","volume":"143","author":"Mitchell","year":"1998","journal-title":"Vet. Rec."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0120","first-page":"1603","article-title":"Anthelmintic effect of rafoxanide against immature Fasciola hepatica in calves","volume":"33","author":"Presidente","year":"1972","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0125","first-page":"1668","article-title":"Anthelmintic activities of fenbedazole against Nematodirus helvetianus in cattle: effect on egg production, embryogeny, and development of larval stages","volume":"39","author":"Samizadeh-Yazd","year":"1978","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0130","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/0014-4894(88)90103-8","article-title":"Fasciola hepatica: perturbation of secretory activity in the vitelline cells by the sodium ionophore monensin","volume":"65","author":"Skuce","year":"1988","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0135","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/BF00930821","article-title":"The effect of the hydrogen ionophore closantel upon the pharmacology and ultrastructure of the adult liver fluke Fasciola hepatica","volume":"76","author":"Skuce","year":"1990","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0140","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/BF00389956","article-title":"The effects of rafoxanide and nitroxynil on the survival, growth and morphology of Fasciola hepatica in rabbits","volume":"46","author":"Stammers","year":"1975","journal-title":"Z. Parasitenkd."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0145","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S0034-5288(18)33452-0","article-title":"The effects of nitroxynil on the survival, growth and morphology of Fasciola hepatica in sheep","volume":"20","author":"Stammers","year":"1976","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0150","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1080\/07924259.1992.9672266","article-title":"Spermatogenesis in Fasciola hepatica: an ultrastructural comparison of the effects of the anthelmintic, triclabendazole (\u201cFasinex\u201d) and the microtubule inhibitor, tubulozole","volume":"22","author":"Stitt","year":"1992","journal-title":"Invertebr. Reprod. Dev."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0155","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1017\/S0031182000079270","article-title":"Fasciola hepatica: the effect of the microtubule inhibitors colchicines and tubulozole-C on the ultrastructure of the adult fluke","volume":"107","author":"Stitt","year":"1993","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2010.11.032_bib0160","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s004360050122","article-title":"Fasciola hepatica: disruption of the vitelline cells in vitro by the sulphoxide metabolite of triclabendazole","volume":"82","author":"Stitt","year":"1996","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0165","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/BF00259527","article-title":"Electron microscope studies of Fasciola hepatica. IX. The fine structure of Mehlis\u2019 gland","volume":"35","author":"Threadgold","year":"1970","journal-title":"Z. Parasitenkd."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0170","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.vetpar.2010.05.012","article-title":"Tegumental surface changes in adult Fasciola hepatica in response to treatment in vivo with triclabendazole in the sheep host","volume":"172","author":"Toner","year":"2010","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0190","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.vetpar.2010.09.008","article-title":"Time-dependent changes to the tegumental system and gastrodermis of adult Fasciola hepatica following treatment in vivo with triclabendazole in the sheep host","volume":"174","author":"Toner","year":"2010","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0180","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1007\/s00436-009-1466-1","article-title":"Standardisation of the egg hatch test for the detection of benzimidazole resistance in parasitic nematodes","volume":"105","author":"von Samson-Himmelstjerna","year":"2009","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2010.11.032_bib0185","first-page":"6","article-title":"Efficacy of injectable clorsulon in the treatment of immature bovine Fasciola hepatica infections","volume":"6","author":"Yazwinski","year":"1985","journal-title":"Agri-Practice"}],"container-title":["Veterinary Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401710006825?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401710006825?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T06:43:38Z","timestamp":1740725018000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304401710006825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":37,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["S0304401710006825"],"URL":"https:\/\/doi.org\/10.1016\/j.vetpar.2010.11.032","relation":{},"ISSN":["0304-4017"],"issn-type":[{"type":"print","value":"0304-4017"}],"subject":[],"published":{"date-parts":[[2011,4]]}}}