{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T22:50:48Z","timestamp":1787871048205,"version":"build-2784847793"},"reference-count":24,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100007757","name":"Agencia Canaria de Investigaci\u00f3n, Innovaci\u00f3n y Sociedad de la Informaci\u00f3n, Gobierno de Canarias, Spain","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007757","id-type":"DOI","asserted-by":"crossref"}]},{"name":"FSE funds"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Parasitology"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1016\/j.vetpar.2013.01.005","type":"journal-article","created":{"date-parts":[[2013,1,16]],"date-time":"2013-01-16T22:31:39Z","timestamp":1358375499000},"page":"106-111","source":"Crossref","is-referenced-by-count":21,"title":["Variation of d-dimer values as assessment of pulmonary thromboembolism during adulticide treatment of heartworm disease in dogs"],"prefix":"10.1016","volume":"195","author":[{"given":"E.","family":"Carret\u00f3n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Morch\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Gonz\u00e1lez-Miguel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Sim\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.C.","family":"Juste","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.","family":"Montoya-Alonso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetpar.2013.01.005_bib0005","unstructured":"American Heartworm Society, 2012. Guidelines for the diagnosis, prevention and management of heartworm (Dirofilaria immitis) infection in dogs (2012). Available at: http:\/\/www.heartwormsociety.org (accessed 15.11.12)."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0010","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.rvsc.2006.09.002","article-title":"Retrospective study of the clinical hematology and the serum biochemistry tests made on canine dirofilariasis cases in an animal hospital population in Bangkok, Thailand","volume":"82","author":"Anuchai","year":"2007","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0015","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1055\/s-0038-1622809","article-title":"Evaluation of the cardiac reader (R) as a point-of-care instrument for measurement of fibrin d-dimers in dogs","volume":"37","author":"Bauer","year":"2009","journal-title":"Tier\u00e4rztl. Prax."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0020","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/j.ijpara.2008.03.002","article-title":"Combined ivermectin and doxycycline treatment has microfilaricidal and adulticidal activity against Dirofilaria immitis in experimentally infected dogs","volume":"38","author":"Bazzocchi","year":"2008","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0025","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.thromres.2006.12.015","article-title":"The dynamic changes of LDH isoenzyme 3 and d-dimer following pulmonary thromboembolism in canine","volume":"120","author":"Ben","year":"2007","journal-title":"Thromb. Res."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0030","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.2460\/ajvr.1989.50.09.1544","article-title":"Enhanced platelet reactivity in heartworm-infected dogs","volume":"50","author":"Boudreaux","year":"1989","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0035","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.vetpar.2011.01.015","article-title":"Dirofilaria immitis infection in dogs: cardiopulmonary biomarker levels","volume":"176","author":"Carret\u00f3n","year":"2011","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0040","article-title":"d-Dimer deposits in lungs and kidneys suggest its use as a marker in the clinical workup of dogs with heartworm (Dirofilaria immitis) disease","author":"Carret\u00f3n","year":"2012","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0045","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1748-5827.2008.00583.x","article-title":"A retrospective study of canine d-dimer concentrations measured using an immunometric \u201cPoint-of-Care\u201d test","volume":"49","author":"Dewhurst","year":"2008","journal-title":"J. Small Anim. Pract."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0050","series-title":"Kirk's Current Veterinary Therapy XIII: Small Animal Practice","first-page":"190","article-title":"Recognition and treatment of disseminated intravascular coagulation","author":"Feldman","year":"2000"},{"key":"10.1016\/j.vetpar.2013.01.005_bib0055","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.vetpar.2005.07.016","article-title":"Clinicopathological findings in naturally occurring cases of babesiosis caused by large form Babesia from dogs of northeastern Italy","volume":"134","author":"Furlanello","year":"2005","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0060","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1476-4431.2009.00388.x","article-title":"Pulmonary thromboembolism","volume":"19","author":"Goggs","year":"2009","journal-title":"J. Vet. Emerg. Crit. Care"},{"key":"10.1016\/j.vetpar.2013.01.005_bib0065","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.2460\/ajvr.1994.55.11.1535","article-title":"Clinical, hematologic, and biochemical findings in dogs after induction of shock by injection of heartworm extract","volume":"55","author":"Kitoh","year":"1994","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0070","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.vetpar.2011.01.021","article-title":"Evaluation of lung pathology in Dirofilaria immitis-experimentally infected dogs treated with doxycycline or a combination of doxycycline and ivermectin before administration of melarsomine dihydrochloride","volume":"176","author":"Kramer","year":"2011","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0075","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.vetpar.2008.09.014","article-title":"Wolbachia and its influence on the pathology and immunology of Dirofilaria immitis infection","volume":"158","author":"Kramer","year":"2008","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0080","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0065-308X(08)00204-2","article-title":"Heartworm disease in animals and humans","volume":"66","author":"McCall","year":"2008","journal-title":"Adv. Parasitol."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0085","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.vetpar.2011.01.011","article-title":"Current prevalence of Dirofilaria immitis in dogs, cats and humans from the island of Gran Canaria, Spain","volume":"176","author":"Montoya-Alonso","year":"2011","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0090","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/j.1939-165X.2012.00416.x","article-title":"Thrombocytosis: a retrospective study of 165 dogs","volume":"41","author":"Neel","year":"2012","journal-title":"Vet. Clin. Pathol."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0095","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1111\/j.1939-1676.2003.tb02522.x","article-title":"The utility of plasma d-dimer to identify thromboembolic disease in dogs","volume":"17","author":"Nelson","year":"2003","journal-title":"J. Vet. Intern. Med."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0100","first-page":"49","article-title":"Clinical laboratory evaluations of seven heartworm infested beagles: during disease development and following treatment","volume":"72","author":"Rawlings","year":"1982","journal-title":"Cornell Vet."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0105","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1128\/CMR.00012-12","article-title":"Human and animal dirofilariasis: the emergence of a zoonotic mosaic","volume":"25","author":"Sim\u00f3n","year":"2012","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0110","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/S0195-5616(03)00096-2","article-title":"Plasma d-dimer for the diagnosis of thromboembolic disorders in dogs","volume":"33","author":"Stokol","year":"2003","journal-title":"Vet. Clin. North Am. Small Anim. Pract."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0115","first-page":"2276","article-title":"ESC Committee for Practice Guidelines (CPG) 2008. Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC)","volume":"29","author":"Torbicki","year":"2008","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.vetpar.2013.01.005_bib0120","series-title":"Recent Advances in Heartworm Disease, Symposium\u201901","first-page":"111","article-title":"Relative utility of echocardiography, radiography, serologic testing and microfilariae counts to predict adult worm burden in dogs naturally infected with heartworms","author":"Venco","year":"2003"}],"container-title":["Veterinary Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401713000307?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401713000307?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T17:22:33Z","timestamp":1745947353000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304401713000307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":24,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S0304401713000307"],"URL":"https:\/\/doi.org\/10.1016\/j.vetpar.2013.01.005","relation":{},"ISSN":["0304-4017"],"issn-type":[{"value":"0304-4017","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}