{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:18:06Z","timestamp":1786997886493,"version":"build-2736575974"},"reference-count":37,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Parasitology"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.vetpar.2014.07.016","type":"journal-article","created":{"date-parts":[[2014,7,23]],"date-time":"2014-07-23T21:30:57Z","timestamp":1406151057000},"page":"20-27","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Genetic polymorphism of Babesia bovis merozoite surface antigens-2 (MSA-2) isolates from bovine blood and Rhipicephalus annulatus ticks in Israel"],"prefix":"10.1016","volume":"205","author":[{"given":"T.","family":"Molad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Fleiderovitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Leibovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Wolkomirsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Erster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Roth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.L.","family":"Mazuz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Markovics","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Shkap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetpar.2014.07.016_bib0005","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S1097-2765(00)80411-6","article-title":"The ves multigene family of B. bovis encodes components of rapid antigenic variation at the infected erythrocytes surface","volume":"5","author":"Allred","year":"2000","journal-title":"Mol. Cell."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0010","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.vetpar.2011.09.021","article-title":"Phylogenetic relationships of Mongolian Babesia bovis isolates based on the merozoite surface antigen (MSA)-1, MSA-2b, and MSA-2c genes","volume":"184","author":"Altangeral","year":"2012","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0015","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ijpara.2011.12.003","article-title":"Functional genomics studies of Rhipicephalus (Boophilus) annulatus ticks in response to infection with the cattle protozoan parasite, Babesia bigemina","volume":"42","author":"Antunes","year":"2012","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0020","doi-asserted-by":"crossref","first-page":"7180","DOI":"10.1128\/IAI.73.11.7180-7189.2005","article-title":"Merozoite surface antigen 2 proteins of Babesia bovis vaccine breakthrough isolates contain a unique hypervariable region composed of degenerate repeats","volume":"73","author":"Berens","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0025","doi-asserted-by":"crossref","first-page":"5769","DOI":"10.1128\/IAI.00802-07","article-title":"Coinfection with antigenically and genetically distinct virulent strains of Babesia bovis is maintained through all phases of the parasite life cycle","volume":"75","author":"Berens","year":"2007","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0030","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1111\/j.1751-0813.2001.tb10931.x","article-title":"Immunity following use of Australian tick fever vaccine: a review of the evidence","volume":"7","author":"Bock","year":"2001","journal-title":"Aust. Vet. J."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0035","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0304-4017(92)90047-D","article-title":"Investigations of breakdowns in protection provided by living Babesia bovis vaccine","volume":"43","author":"Bock","year":"1992","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0040","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/j.1751-0813.1995.tb03558.x","article-title":"Studies on failure of T strain live Babesia bovis vaccine","volume":"72","author":"Bock","year":"1995","journal-title":"Aust. Vet. J."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0045","doi-asserted-by":"crossref","first-page":"S247","DOI":"10.1017\/S0031182004005190","article-title":"Babesiosis of cattle","volume":"129","author":"Bock","year":"2004","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2014.07.016_bib0050","first-page":"353","article-title":"Some aspects of the epidemiology and control of bovine babesiosis in Australia","volume":"50","author":"Callow","year":"1979","journal-title":"J. S. Afr. Vet. Assoc."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0055","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.vetpar.2006.01.038","article-title":"Genetic basis for GPI anchor merozoite surface antigen polymorphism of Babesia and resulting antigenic diversity","volume":"138","author":"Carcy","year":"2006","journal-title":"Vet. Parasitol."},{"issue":"Web Server Issue","key":"10.1016\/j.vetpar.2014.07.016_bib0060","doi-asserted-by":"crossref","first-page":"W465","DOI":"10.1093\/nar\/gkn180","article-title":"Phylogeny.fr: robust phylogenetic analysis for the non-specialist","volume":"36","author":"Dereeper","year":"2008","journal-title":"Nucl. Acids Res."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0065","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/j.1365-2958.2005.05007.x","article-title":"Antigenic variation by protozoan parasites: insights from Babesia bovis","volume":"59","author":"Dzikowski","year":"2006","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0070","doi-asserted-by":"crossref","first-page":"3566","DOI":"10.1128\/IAI.70.7.3566-3575.2002","article-title":"The Babesia bovis merozoite surface antigen 2 locus contains four tandemly arranged and expressed genes encoding immunologically distinct proteins","volume":"70","author":"Florin-Christensen","year":"2002","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0075","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ijpara.2012.09.008","article-title":"Bovine babesiosis in the 21st century: advances in biology and functional genomics","volume":"43","author":"Gohil","year":"2013","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0080","doi-asserted-by":"crossref","first-page":"3155","DOI":"10.1128\/JCM.00766-07","article-title":"Persistently infected calves as reservoirs for acquisition and transovarial transmission of Babesia bovis by Rhipicephalus (Boophilus) microplus","volume":"45","author":"Howell","year":"2007","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0085","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.molbiopara.2010.03.017","article-title":"Genotypic diversity of merozoite surface antigen 1 of Babesia bovis within an endemic population","volume":"172","author":"Lau","year":"2010","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0090","doi-asserted-by":"crossref","first-page":"5388","DOI":"10.1128\/IAI.73.9.5388-5394.2005","article-title":"Sequence variation and immunologic cross-reactivity among Babesia bovis merozoite surface antigen 1 proteins from vaccine strains and vaccine breakthrough isolates","volume":"73","author":"Leroith","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0095","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1751-0813.1997.tb14197.x","article-title":"Genotypic diversity in field isolates of Babesia bovis from cattle with babesiosis after vaccination","volume":"75","author":"Lew","year":"1997","journal-title":"Aust. Vet. J."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0100","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0034-5288(18)33242-9","article-title":"The selection of larvae of Boophilus microplus infected with Babesia bovis (syn B argentina)","volume":"23","author":"Mahoney","year":"1977","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0105","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1017\/S0031182011001995","article-title":"Genetic diversity of Babesia bovis in virulent and attenuated strains","volume":"39","author":"Mazuz","year":"2012","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2014.07.016_bib0110","doi-asserted-by":"crossref","first-page":"6448","DOI":"10.1128\/IAI.70.11.6448-6455.2002","article-title":"Babesia bovis merozoite surface antigen 2 proteins are expressed on the merozoite and sporozoite surface, and specific antibodies inhibit attachment and invasion of erythrocytes","volume":"70","author":"Mosqueda","year":"2002","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0115","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1128\/IAI.70.3.1599-1603.2002","article-title":"Babesia bovis merozoite surface antigen 1 and rhoptry-associated protein 1 are expressed in sporozoites, and specific antibodies inhibit sporozoite attachment to erythrocytes","volume":"70","author":"Mosqueda","year":"2002","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0120","first-page":"36","article-title":"Analysis of immunogenic relevant proteins in Rhipicephalus (Boophilus) annulatus tick","volume":"6","author":"Nikpay","year":"2012","journal-title":"J. Arthropod Borne Dis."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0125","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.vetpar.2005.03.007","article-title":"Babesia spp. infection in Boophilus microplus engorged females and eggs in Sao Paulo State, Brazil","volume":"130","author":"Oliveira","year":"2005","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0130","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1053\/tvjl.2001.0703","article-title":"Babesia bovis and B. bigemina: persistence of infection in friesian cows following vaccination with live antibabesial vaccines","volume":"164","author":"Pipano","year":"2002","journal-title":"Vet. J."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0135","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1749-6632.2000.tb05286.x","article-title":"Culture-derived parasites in vaccination of cattle against tick-borne diseases","volume":"916","author":"Shkap","year":"2000","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0140","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.vetpar.2005.01.013","article-title":"Vaccination of older Bos taurus bulls against bovine babesiosis","volume":"129","author":"Shkap","year":"2005","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0145","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.pt.2007.07.003","article-title":"Attenuated vaccines for tropical theileriosis, babesiosis and heartwater: the continuing necessity","volume":"23","author":"Shkap","year":"2007","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0150","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.vetpar.2013.07.015","article-title":"The molecular prevalence and MSA-2b gene-based genetic diversity of Babesia bovis in dairy cattle in Thailand","volume":"197","author":"Simking","year":"2013","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0155","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.meegid.2013.07.001","article-title":"Genetic diversity of merozoite surface antigens in Babesia bovis detected from Sri Lankan cattle","volume":"19","author":"Sivakumar","year":"2013","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0160","doi-asserted-by":"crossref","first-page":"6865","DOI":"10.1128\/IAI.68.12.6865-6870.2000","article-title":"Merozoite surface antigen 1 (MSA-1) locus and identification of a cross-reactive inhibition-sensitive MSA-1 epitope","volume":"68","author":"Suarez","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0165","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.parint.2013.09.003","article-title":"Diversity of Babesia bovis merozoite surface antigen genes in the Philippines","volume":"63","author":"Tattiyapong","year":"2014","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0170","first-page":"108","article-title":"Passive transfer to newborn calves of maternal antibodies against Babesia bigemina and Babesia berbera","volume":"31","author":"Weismann","year":"1974","journal-title":"Refuah Vet."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0175","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0166-6851(02)00329-8","article-title":"Babesia bovis merozoite surface protein-2c (MSA-2c) contains highly immunogenic, conserved B-cell epitopes that elicit neutralization-sensitive antibodies in cattle","volume":"127","author":"Wilkowsky","year":"2003","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.vetpar.2014.07.016_bib0180","first-page":"63","article-title":"Taking advantage of the polymorphism of the MSA-2 family for Babesia bovis strain characterization","volume":"49","author":"Wilkowsky","year":"2007","journal-title":"Parasitologia"},{"key":"10.1016\/j.vetpar.2014.07.016_bib0185","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.vetpar.2006.01.037","article-title":"Erythrocyte invasion by Babesia parasites: current advances in the elucidation of the molecular interactions between the protozoan ligands and host receptors in the invasion stage","volume":"138","author":"Yokoyama","year":"2006","journal-title":"Vet. Parasitol."}],"container-title":["Veterinary Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401714004038?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401714004038?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T23:54:51Z","timestamp":1565654091000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304401714004038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":37,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S0304401714004038"],"URL":"https:\/\/doi.org\/10.1016\/j.vetpar.2014.07.016","relation":{},"ISSN":["0304-4017"],"issn-type":[{"value":"0304-4017","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genetic polymorphism of Babesia bovis merozoite surface antigens-2 (MSA-2) isolates from bovine blood and Rhipicephalus annulatus ticks in Israel","name":"articletitle","label":"Article Title"},{"value":"Veterinary Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetpar.2014.07.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}