{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T11:37:23Z","timestamp":1781005043477,"version":"3.54.1"},"reference-count":41,"publisher":"Elsevier BV","issue":"3-4","license":[{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Parasitology"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1016\/j.vetpar.2015.06.008","type":"journal-article","created":{"date-parts":[[2015,6,14]],"date-time":"2015-06-14T06:05:34Z","timestamp":1434261934000},"page":"306-311","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Serum antibody responses in pigs trickle-infected with Ascaris and Trichuris: Heritabilities and associations with parasitological findings"],"prefix":"10.1016","volume":"211","author":[{"given":"Helene","family":"Kringel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stig Milan","family":"Thamsborg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi Huus","family":"Petersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald Heinz Herbert","family":"G\u00f6ring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Skallerup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6673-8505","authenticated-orcid":false,"given":"Peter","family":"Nejsum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetpar.2015.06.008_bib0005","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1086\/301844","article-title":"Multipoint quantitative-trait linkage analysis in general pedigrees","volume":"62","author":"Almasy","year":"1998","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0010","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1038\/nri2199","article-title":"Protective immune mechanisms in helminth infection","volume":"7","author":"Anthony","year":"2007","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0015","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1159\/000236456","article-title":"Specific immunological unresponsiveness following active primary responses to proteins in the weaning diet of piglets","volume":"101","author":"Bailey","year":"1993","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0020","doi-asserted-by":"crossref","first-page":"3860","DOI":"10.1128\/IAI.69.6.3860-3868.2001","article-title":"B cells and antibodies are required for resistance to the parasitic gastrointestinal nematode Trichuris muris","volume":"69","author":"Blackwell","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0025","doi-asserted-by":"crossref","first-page":"950","DOI":"10.2307\/3279928","article-title":"The immune response and acquired resistance to Ascaris suum infection in mice with an X-linked B lymphocyte defect","volume":"63","author":"Brown","year":"1977","journal-title":"J. Parasitol."},{"issue":"Suppl","key":"10.1016\/j.vetpar.2015.06.008_bib0030","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1017\/S0031182099005776","article-title":"The immune response and the evaluation of acquired immunity against gastrointestinal nematodes in cattle: a review","volume":"120","author":"Claerebout","year":"2000","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2015.06.008_bib0035","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.vetimm.2005.07.006","article-title":"Genetic selection for high and low immune response in pigs: effects on immunoglobulin isotype expression","volume":"108","author":"Crawley","year":"2005","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0040","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1086\/605844","article-title":"Heritable factors play a major role in determining host responses to Wuchereria bancrofti infection in an isolated South Pacific island population","volume":"200","author":"Cuenco","year":"2009","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0045","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/0020-7519(94)00213-8","article-title":"Genetic factors affecting antibody responses to four species of nematode parasite in Romney ewe lambs","volume":"25","author":"Douch","year":"1995","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0050","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0304-4017(92)90017-4","article-title":"Resistance to Ascaris suum in parasite na\u00efve and naturally exposed growers, finishers and sows","volume":"41","author":"Eriksen","year":"1992","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0055","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1079\/JOH2002163","article-title":"Serological responses to Ascaris suum adult worm antigens in Iberian finisher pigs","volume":"77","author":"Frontera","year":"2003","journal-title":"J. Helminthol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0060","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0304-4017(93)90049-S","article-title":"Influence of host genetics upon antibody responses against gastrointestinal nematode infections in cattle","volume":"46","author":"Gasbarre","year":"1993","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0065","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1086\/591946","article-title":"High heritability but uncertain mode of inheritance for total serum IgE level and Schistosoma mansoni infection intensity in a schistosomiasis-endemic Brazilian population","volume":"198","author":"Grant","year":"2008","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0070","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1006\/expr.1993.1074","article-title":"Trichuris suis: a zinc metalloprotease from culture fluids of adult parasites","volume":"77","author":"Hill","year":"1993","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0075","first-page":"405","article-title":"Immune mechanisms to Ascaris suum in inbred guinea-pigs. I. Passive transfer of immunity by cells or serum","volume":"32","author":"Khoury","year":"1977","journal-title":"Immunology"},{"key":"10.1016\/j.vetpar.2015.06.008_bib0080","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1365-3024.2005.00753.x","article-title":"Immuno-epidemiology of Ascaris lumbricoides infection in a high transmission community: antibody responses and their impact on current and future infection intensity","volume":"27","author":"King","year":"2005","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0085","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1365-3024.2007.00943.x","article-title":"Trichuris suis excretory\/secretory antigen-specific antibodies in serum from single-inoculated pigs","volume":"29","author":"Kringel","year":"2007","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0090","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1017\/S0031182099004503","article-title":"Seasonal variation in development and survival of Ascaris suum and Trichuris suis eggs on pastures","volume":"119","author":"Larsen","year":"1999","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2015.06.008_bib0095","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/BF00931899","article-title":"Response to repeated inoculations with Ascaris suum eggs in pigs during the fattening period. II. Specific IgA, IgG, and IgM antibodies determined by enzyme-linked immunosorbent assay","volume":"79","author":"Lind","year":"1993","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0100","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0304-4017(89)90165-9","article-title":"Production and distribution of immunoglobulin-bearing cells in the intestine of young pigs infected with Ascaris suum","volume":"34","author":"Marbella","year":"1989","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0105","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1002\/gepi.5","article-title":"Genome-wide linkage analyses of total serum IgE using variance components analysis in asthmatic families","volume":"20","author":"Mathias","year":"2001","journal-title":"Genet. Epidemiol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0110","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.chom.2008.08.014","article-title":"Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection","volume":"4","author":"McCoy","year":"2008","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.vetpar.2015.06.008_bib0115","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1365-3024.2005.00752.x","article-title":"Host immune reactions and worm kinetics during the expulsion of Ascaris suum in pigs","volume":"27","author":"Miquel","year":"2005","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0120","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1017\/S135772980005342X","article-title":"Genetic and phenotypic relationships among faecal egg count, anti-nematode antibody level and live weight in Angus cattle","volume":"76","author":"Morris","year":"2003","journal-title":"Animal Sci."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0125","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/hdy.2008.131","article-title":"High heritability for Ascaris and Trichuris infection levels in pigs","volume":"102","author":"Nejsum","year":"2009","journal-title":"Heredity"},{"key":"10.1016\/j.vetpar.2015.06.008_bib0130","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1645\/GE-1987.1","article-title":"Population dynamics of Ascaris suum in trickle-infected pigs","volume":"95","author":"Nejsum","year":"2009","journal-title":"J. Parasitol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0135","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1017\/S0031182009005976","article-title":"Population dynamics of Trichuris suis in trickle-infected pigs","volume":"136","author":"Nejsum","year":"2009","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2015.06.008_bib0140","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1038\/hdy.2012.90","article-title":"Genome-wide association and regional heritability mapping to identify loci underlying variation in nematode resistance and body weight in Scottish Blackface lambs","volume":"110","author":"Riggio","year":"2013","journal-title":"Heredity"},{"key":"10.1016\/j.vetpar.2015.06.008_bib0145","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0020-7519(97)00022-2","article-title":"Transmission dynamics of helminth parasites of pigs on continuous pasture: Ascaris suum and Trichuris suis","volume":"27","author":"Roepstorff","year":"1997","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0150","series-title":"Epidemiology, diagnosis and control of helminth parasites of swine","author":"Roepstorff","year":"1998"},{"key":"10.1016\/j.vetpar.2015.06.008_bib0155","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.ijpara.2012.02.010","article-title":"Detection of a quantitative trait locus associated with resistance to Ascaris suum infection in pigs","volume":"42","author":"Skallerup","year":"2012","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0160","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0165-2427(99)00134-8","article-title":"How lambs control infection with Ostertagia circumcincta","volume":"72","author":"Stear","year":"1999","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0165","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/0165-2427(82)90022-8","article-title":"Development of immune responsiveness to Ascaris suum antigens in pigs vaccinated with ultraviolet-attenuated eggs","volume":"3","author":"Urban","year":"1982","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0170","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0014-4894(88)90051-3","article-title":"Ascaris suum: development of intestinal immunity to infective second-stage larvae in swine","volume":"66","author":"Urban","year":"1988","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0175","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.vetpar.2012.04.024","article-title":"Evaluation of a serodiagnostic test using Ascaris suum haemoglobin for the detection of roundworm infections in pig populations","volume":"189","author":"Vlaminck","year":"2012","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0180","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1017\/S0031182000052173","article-title":"Immune expulsion of Trichuris muris from mice during a primary infection: analysis of the components involved","volume":"70","author":"Wakelin","year":"1975","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2015.06.008_bib0185","doi-asserted-by":"crossref","first-page":"921","DOI":"10.4269\/ajtmh.1999.60.921","article-title":"Genetic analysis of susceptibility to infection with Ascaris lumbricoides","volume":"60","author":"Williams-Blangero","year":"1999","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0190","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/gepi.0187","article-title":"Genetic component to susceptibility to Trichuris trichiura: evidence from two Asian populations","volume":"22","author":"Williams-Blangero","year":"2002","journal-title":"Genet. Epidemiol"},{"key":"10.1016\/j.vetpar.2015.06.008_bib0195","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1086\/524060","article-title":"Localization of multiple quantitative trait loci influencing susceptibility to infection with Ascaris lumbricoides","volume":"197","author":"Williams-Blangero","year":"2008","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0200","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1086\/533493","article-title":"Two quantitative trait loci influence whipworm (Trichuris trichiura) infection in a Nepalese population","volume":"197","author":"Williams-Blangero","year":"2008","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.vetpar.2015.06.008_bib0205","series-title":"Ascaris: The Neglected Parasite","first-page":"315","article-title":"Genetics of human host susceptibility to ascariasis","author":"Williams-Blangero","year":"2013"}],"container-title":["Veterinary Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401715002897?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401715002897?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,26]],"date-time":"2019-08-26T18:56:01Z","timestamp":1566845761000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304401715002897"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7]]},"references-count":41,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["S0304401715002897"],"URL":"https:\/\/doi.org\/10.1016\/j.vetpar.2015.06.008","relation":{},"ISSN":["0304-4017"],"issn-type":[{"value":"0304-4017","type":"print"}],"subject":[],"published":{"date-parts":[[2015,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Serum antibody responses in pigs trickle-infected with Ascaris and Trichuris: Heritabilities and associations with parasitological findings","name":"articletitle","label":"Article Title"},{"value":"Veterinary Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetpar.2015.06.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}