{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:43:16Z","timestamp":1792784596934,"version":"4.5.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Global Alliance for Veterinary Medicines"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Parasitology"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.vetpar.2016.11.017","type":"journal-article","created":{"date-parts":[[2016,11,20]],"date-time":"2016-11-20T19:45:32Z","timestamp":1479671132000},"page":"32-38","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Development of a rapid antibody test for point-of-care diagnosis of animal African trypanosomosis"],"prefix":"10.1016","volume":"233","author":[{"given":"Alain","family":"Boulang\u00e9","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davita","family":"Pillay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyrille","family":"Chevtzoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Biteau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Com\u00e9 de Gra\u00e7a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonie","family":"Rempeters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Theodoridis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Th\u00e9o","family":"Baltz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetpar.2016.11.017_bib0005","doi-asserted-by":"crossref","first-page":"e359","DOI":"10.1016\/S2214-109X(14)70203-7","article-title":"Sensitivity and specificity of HAT Sero-K-SeT: a rapid diagnostic test for serodiagnosis of sleeping sickness caused by Trypanosoma brucei gambiense: a case-control study","volume":"2","author":"B\u00fcscher","year":"2014","journal-title":"Lancet Glob. Health"},{"key":"10.1016\/j.vetpar.2016.11.017_bib0010","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s00436-011-2452-y","article-title":"Highly debilitating natural Trypanosoma vivax infections in Brazilian calves: epidemiology, pathology, and probable transplacental transmission","volume":"110","author":"Batista","year":"2012","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0015","unstructured":"Bengaly, Z., Kanwe, A.B., Duvallet, G., 1995. Evaluation of an antigen detection-ELISA test for the diagnosis of trypanosomiasis in naturally infected cattle. Trop. Med. Parasitol. Off. Organ Dtsch. Tropenmedizinische Ges. Dtsch. Ges. F\u00fcr Tech. Zusammenarbeit GTZ 46, 284\u2013286."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0020","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.vetpar.2015.05.008","article-title":"Surra Sero K-SeT, a new immunochromatographic test for serodiagnosis of Trypanosoma evansi infection in domestic animals","volume":"211","author":"Birhanu","year":"2015","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0025","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0030","first-page":"5","article-title":"High prevalence of drug resistance in animal trypanosomes without a history of drug exposure","author":"Chitanga","year":"2011","journal-title":"PLoS Negl. Trop Dis."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0035","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1475-9292-3-3","article-title":"Variable Surface Glycoprotein RoTat 1.2 PCR as a specific diagnostic tool for the detection of Trypanosoma evansi infections","volume":"3","author":"Claes","year":"2004","journal-title":"Kinetoplastid Biol. Dis."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0040","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1080\/00034983.2001.11813624","article-title":"The analysis of the cross-reactions occurring in antibody-ELISA for the detection of trypanosomes can improve identification of the parasite species involved","volume":"95","author":"Desquesnes","year":"2001","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0045","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0304-4017(98)00173-3","article-title":"Sensitivity and specificity of antigen-capture ELISAs for diagnosis of Trypanosoma congolense and Trypanosoma vivax infections in cattle","volume":"79","author":"Eisler","year":"1998","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0050","first-page":"12","volume":"30","author":"Geigy","year":"1973","journal-title":"Acta Trop."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0055","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.molbiopara.2014.05.001","article-title":"Antigenic variation in African trypanosomes","volume":"195","author":"Horn","year":"2014","journal-title":"Mol. Biochem. Parasitol."},{"issue":"pt 3","key":"10.1016\/j.vetpar.2016.11.017_bib0060","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1017\/S0031182000080835","article-title":"Repetitive proteins from the flagellar cytoskeleton of African trypanosomes are diagnostically useful antigens","volume":"110","author":"Imboden","year":"1995","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2016.11.017_bib0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003480","article-title":"Accuracy of individual rapid tests for serodiagnosis of gambiense sleeping sickness in West Africa","volume":"9","author":"Jamonneau","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0070","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1080\/01652176.1988.9694144","article-title":"Quantitative correlation of parasitological and serological techniques for the diagnosis of Trypanosoma congolense infection in cattle","volume":"10","author":"Jongejan","year":"1988","journal-title":"Vet. Q."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0075","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0308-521X(98)00086-9","article-title":"Measuring the costs of African animal trypanosomosis, the potential benefits of control and returns to research","volume":"59","author":"Kristjanson","year":"1999","journal-title":"Agric. Syst."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0080","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/0020-7519(76)90027-8","article-title":"Studies on Trypanosoma vivax: infectivity and serial maintenance of natural bovine isolates in mice","volume":"6","author":"Leeflang","year":"1976","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0085","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/BF02235328","article-title":"Evaluation of an indirect fluorescent antibody test, enzyme-linked immunosorbent assay and quantification of immunoglobulins in the diagnosis of bovine trypanosomiasis","volume":"10","author":"Luckins","year":"1978","journal-title":"Trop. Anim. Health Prod."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0090","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0304-4017(94)00667-2","article-title":"Comparative sensitivity of antigen-detection enzyme immunosorbent assay and the microhaematocrit centrifugation technique in the diagnosis of Trypanosoma brucei infections in cattle","volume":"56","author":"Masake","year":"1995","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0095","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1128\/EC.00405-07","article-title":"Molecular and biochemical characterization of a cathepsin B-Like protease family unique to Trypanosoma congolense","volume":"7","author":"Mendoza-Palomares","year":"2008","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.vetpar.2016.11.017_bib0100","unstructured":"Nantulya, V.M., Lindqvist, K.J., 1989. Antigen-detection enzyme immunoassays for the diagnosis of Trypanosoma vivax, T. congolense and T. brucei infections in cattle. Trop. Med. Parasitol. Off. Organ Dtsch. Tropenmedizinische Ges. Dtsch. Ges. F\u00fcr Tech. Zusammenarbeit GTZ 40, 267\u2013272."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0105","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.vetpar.2014.01.009","article-title":"Diagnostic value of the recombinant tandem repeat antigen TeGM6-4r for surra in water buffaloes","volume":"201","author":"Nguyen","year":"2014","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0110","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1292\/jvms.14-0330","article-title":"Application of crude and recombinant ELISAs and immunochromatographic test for serodiagnosis of animal trypanosomosis in the Umkhanyakude district of KwaZulu-Natal province, South Africa","volume":"77","author":"Nguyen","year":"2015","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0115","doi-asserted-by":"crossref","first-page":"4319","DOI":"10.1007\/s00436-015-4672-z","article-title":"A TeGM6-4r antigen-based immunochromatographic test (ICT) for animal trypanosomosis","volume":"114","author":"Nguyen","year":"2015","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0120","doi-asserted-by":"crossref","first-page":"e0004420","DOI":"10.1371\/journal.pntd.0004420","article-title":"An anti-proteome nanobody library approach yields a specific immunoassay for Trypanosoma congolense diagnosis targeting glycosomal aldolase","volume":"10","author":"Odongo","year":"2016","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0125","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1111\/j.1469-0691.2010.03279.x","article-title":"Point-of-care tests for diagnosing infections in the developing world","volume":"16","author":"Peeling","year":"2010","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0078565","article-title":"Trypanosoma vivax GM6 Antigen: a candidate antigen for diagnosis of animal African trypanosomosis in cattle","volume":"8","author":"Pillay","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.vetpar.2016.11.017_bib0135","doi-asserted-by":"crossref","first-page":"e3373","DOI":"10.1371\/journal.pntd.0003373","article-title":"Evaluation of the diagnostic accuracy of prototype rapid tests for human African trypanosomiasis","volume":"8","author":"Sternberg","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0140","doi-asserted-by":"crossref","first-page":"e2087","DOI":"10.1371\/journal.pntd.0002087","article-title":"Proteomic selection of immunodiagnostic antigens for human African trypanosomiasis and generation of a prototype lateral flow immunodiagnostic device","volume":"7","author":"Sullivan","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0145","doi-asserted-by":"crossref","first-page":"e2976","DOI":"10.1371\/journal.pntd.0002976","article-title":"Identification of sVSG117 as an Immunodiagnostic antigen and evaluation of a dual-antigen lateral flow test for the diagnosis of human African trypanosomiasis","volume":"8","author":"Sullivan","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0150","doi-asserted-by":"crossref","first-page":"813","DOI":"10.20506\/rst.33.3.2320","article-title":"Animal trypanosomosis: making quality control of trypanocidal drugs possible","volume":"33","author":"Sutcliffe","year":"2014","journal-title":"Rev. Sci. Tech. Int. Off. Epizoot."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0155","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s00436-011-2632-9","article-title":"Tandem repeat protein as potential diagnostic antigen for Trypanosoma evansi infection","volume":"110","author":"Thuy","year":"2012","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0160","first-page":"409","article-title":"Comparisons of variable antigenic types produced by trypanosome strains of the subgenus Trypanozoon","volume":"57","author":"Van Meirvenne","year":"1977","journal-title":"Ann. Soc. Belge M\u00e9d. Trop."},{"key":"10.1016\/j.vetpar.2016.11.017_bib0165","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/0014-4894(74)90107-6","article-title":"Trypanosoma congolense: I. Clinical observations of experimentally infected cattle","volume":"36","author":"Wellde","year":"1974","journal-title":"Exp. Parasitol."}],"container-title":["Veterinary Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401716304964?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401716304964?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,28]],"date-time":"2019-04-28T23:28:34Z","timestamp":1556494114000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304401716304964"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":33,"alternative-id":["S0304401716304964"],"URL":"https:\/\/doi.org\/10.1016\/j.vetpar.2016.11.017","relation":{},"ISSN":["0304-4017"],"issn-type":[{"value":"0304-4017","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of a rapid antibody test for point-of-care diagnosis of animal African trypanosomosis","name":"articletitle","label":"Article Title"},{"value":"Veterinary Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetpar.2016.11.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}