{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T01:40:35Z","timestamp":1788486035447,"version":"build-2803163510"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Mexican National Council on Science and Technology","award":["314686"],"award-info":[{"award-number":["314686"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Parasitology"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.vetpar.2017.02.001","type":"journal-article","created":{"date-parts":[[2017,2,3]],"date-time":"2017-02-03T05:02:24Z","timestamp":1486098144000},"page":"34-37","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Pulmonary hypertension in dogs with heartworm before and after the adulticide protocol recommended by the American Heartworm Society"],"prefix":"10.1016","volume":"236","author":[{"given":"B.","family":"Serrano-Parre\u00f1o","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Carret\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Caro-Vadillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Falc\u00f3n-Cord\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Falc\u00f3n-Cord\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.","family":"Montoya-Alonso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetpar.2017.02.001_bib0005","first-page":"655","article-title":"Pulmonary arterial lesions in canine dirofilariasis","volume":"22","author":"Adcock","year":"1961","journal-title":"Am. J. Vet. Res"},{"key":"10.1016\/j.vetpar.2017.02.001_bib0010","series-title":"Current Canine Guidelines for the Prevention Diagnosis and Management of Heartworm (Dirofilaria Immitis) Infection in Dogs","author":"American Heartworm Society","year":"2014"},{"key":"10.1016\/j.vetpar.2017.02.001_bib0015","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1136\/vr.116.20.539","article-title":"Experimental production of lesions in canine pulmonary arteries similar to those produced by Dirofilaria immitis infection","volume":"116","author":"Atwell","year":"1985","journal-title":"Vet. Rec."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0020","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0021-9975(88)90043-6","article-title":"Pulmonary changes associated with dead filariae (Dirofilaria immitis) and concurrent antigenic exposure in dogs","volume":"98","author":"Atwell","year":"1988","journal-title":"J. Comp. Pathol."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0025","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.cvsm.2009.06.003","article-title":"Heartworm biology, treatment, and control","volume":"39","author":"Bowman","year":"2009","journal-title":"Vet. Clin. North Am. Small Anim. Pract."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0030","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.vetpar.2013.01.005","article-title":"Variation of D-dimer values as assessment of pulmonary thromboembolism during adulticide treatment of heartworm disease in dogs","volume":"195","author":"Carret\u00f3n","year":"2013","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0035","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.vetpar.2014.08.015","article-title":"Evaluation of cardiopulmonary biomarkers during classic adulticide treatment versus the American Heartworm Society recommended treatment protocol in dogs infected by Dirofilaria immitis","volume":"206","author":"Carret\u00f3n","year":"2014","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0040","series-title":"Proceedings of the Heartworm Symposium \u201895. American Heartworm Society","first-page":"113","article-title":"Influence of number of parasites and exercise on the severity of heartworm disease in dogs","author":"Dillon","year":"1995"},{"key":"10.1016\/j.vetpar.2017.02.001_bib0045","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.molbiopara.2011.10.010","article-title":"Excretory\/secretory antigens from Dirofilaria immitis adult worms interact with the host fibrinolytic system involving the vascular endothelium","volume":"181","author":"Gonz\u00e1lez-Miguel","year":"2012","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0050","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1186\/s13071-015-0799-0","article-title":"Can the activation of plasminogen\/plasmin system of the host by metabolic products of Dirofilaria immitis participate in heartworm disease endarteritis?","volume":"8","author":"Gonz\u00e1lez-Miguel","year":"2015","journal-title":"Parasit. Vectors"},{"key":"10.1016\/j.vetpar.2017.02.001_bib0055","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.cvsm.2010.03.011","article-title":"Pulmonary hypertension in dogs: diagnosis and therapy","volume":"40","author":"Kellihan","year":"2010","journal-title":"Vet. Clin. North Am. Small Anim. Pract."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0060","series-title":"Small Animal Cardiovascular Medicine Textbook","first-page":"370","article-title":"Heartworm infection and disease (Dirofilariasis)","author":"Kittleson","year":"1998"},{"key":"10.1016\/j.vetpar.2017.02.001_bib0065","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.vetpar.2011.01.021","article-title":"Evaluation of lung pathology in Dirofilaria immitis-experimentally infected dogs treated with doxycycline or a combination of doxycycline and ivermectin before administration of melarsomine dihydrochloride","volume":"176","author":"Kramer","year":"2011","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0070","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.vetpar.2015.02.036","article-title":"Acute phase protein response in heartworm-infected dogs after adulticide treatment","volume":"209","author":"M\u00e9ndez","year":"2015","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0075","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0065-308X(08)00204-2","article-title":"Heartworm disease in animals and humans","volume":"66","author":"McCall","year":"2008","journal-title":"Adv. Parasitol."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0080","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.vetpar.2011.01.011","article-title":"Current prevalence of Dirofilaria immitis in dogs, cats and humans from the island of Gran Canaria","volume":"176","author":"Montoya-Alonso","year":"2011","journal-title":"Spain Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0085","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.vetpar.2015.12.005","article-title":"The impact of the climate on the epidemiology of Dirofilaria immitis in the pet population of the Canary Islands","volume":"216","author":"Montoya-Alonso","year":"2016","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0090","first-page":"711","article-title":"Development and resolution of pulmonary disease in heartworm infection: illustrated review","volume":"17","author":"Rawlings","year":"1981","journal-title":"J. Am. Anim. Hosp. Assoc."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0095","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1128\/CMR.00012-12","article-title":"Human and animal dirofilariasis: the emergence of a zoonotic mosaic","volume":"25","author":"Sim\u00f3n","year":"2012","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0100","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1292\/jvms.67.1155","article-title":"Elevated endothelin-1 expression in dogs with heartworm disease","volume":"67","author":"Uchide","year":"2005","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0105","series-title":"Recent Advances in Heartworm Disease, Symposium \u201901","first-page":"111","article-title":"Relative utility of echocardiography, radiography, serologic testing and microfilariae counts to predict adult worm burden in dogs naturally infected with heartworms","author":"Venco","year":"2003"},{"key":"10.1016\/j.vetpar.2017.02.001_bib0110","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.vetpar.2014.08.018","article-title":"Evaluation of C-reactive protein as a clinical biomarker in naturally heartworm-infected dogs: a field study","volume":"206","author":"Venco","year":"2014","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0115","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.vetpar.2014.08.016","volume":"206","author":"Venco","year":"2014","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2017.02.001_bib0120","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1111\/jvim.13911","article-title":"Diagnostic value of right pulmonary artery distensibility index in dogs with pulmonary hypertension: comparison with doppler echocardiographic estimates of pulmonary arterial pressure","volume":"30","author":"Visser","year":"2016","journal-title":"J. Vet. Intern. Med."}],"container-title":["Veterinary Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401717300390?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401717300390?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,4]],"date-time":"2018-09-04T17:24:37Z","timestamp":1536081877000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304401717300390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":24,"alternative-id":["S0304401717300390"],"URL":"https:\/\/doi.org\/10.1016\/j.vetpar.2017.02.001","relation":{},"ISSN":["0304-4017"],"issn-type":[{"value":"0304-4017","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pulmonary hypertension in dogs with heartworm before and after the adulticide protocol recommended by the American Heartworm Society","name":"articletitle","label":"Article Title"},{"value":"Veterinary Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetpar.2017.02.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}