{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T19:20:51Z","timestamp":1783970451660,"version":"3.55.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Parasitology"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.vetpar.2026.110697","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:07:19Z","timestamp":1767917239000},"page":"110697","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Date seed\u2013and licorice\u2013derived nanoemulsions inhibit clinostomid metacercariae recovered from naturally infected Nile tilapia (Oreochromis niloticus): First report"],"prefix":"10.1016","volume":"343","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7838-6538","authenticated-orcid":false,"given":"Olfat A.","family":"Mahdy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai A.","family":"Salem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fady Sayed","family":"Youssef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed S.","family":"Kamel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reem M.","family":"Ramadan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vetpar.2026.110697_bib1","doi-asserted-by":"crossref","DOI":"10.1007\/s10493-025-01085-9","article-title":"Acaricidal activity of Astragalus polysaccharides nanoemulsion against camel tick, Hyalomma dromedarii","author":"Abdel-Radi","year":"2025","journal-title":"Exp. Appl. Acarol."},{"key":"10.1016\/j.vetpar.2026.110697_bib2","first-page":"44","article-title":"Mycogenic Zinc Nanoparticles with Antimicrobial, Antioxidant, Antiviral, Anticancer and anti-Alzheimer Activities Mitigate the Aluminium Toxicity in Mice: Effects on Liver, Kidney, and Brain Health and Growth Performance","author":"Al-Gheffari","year":"2024","journal-title":"Pak. Vet. J."},{"key":"10.1016\/j.vetpar.2026.110697_bib3","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/s13205-023-03835-1","article-title":"Reactive oxygen species induced oxidative damage to DNA, lipids, and proteins of antibiotic-resistant bacteria by plant-based silver nanoparticles","volume":"13","author":"Ali","year":"2023","journal-title":"3 Biotech"},{"key":"10.1016\/j.vetpar.2026.110697_bib4","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-44251-y","article-title":"Date (Phoenix dactylifera L.) seed oil is an agro-industrial waste with biopreservative effects and antimicrobial activity","volume":"13","author":"Alkhalidy","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.vetpar.2026.110697_bib5","first-page":"43","article-title":"Biosynthesis of Salvia hispanica Based Silver Nanoparticles and Evaluation of their Antibacterial Activity in-vitro and Rat Model. Pak","author":"ALRashdi","year":"2023","journal-title":"Vet. J."},{"key":"10.1016\/j.vetpar.2026.110697_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/JPBS.JPBS_168_18","article-title":"Date palm (Phoenix dactylifera L.) fruit as potential antioxidant and antimicrobial agents","volume":"11","author":"Al-Shwyeh","year":"2019","journal-title":"J. Pharm. Bioallied Sci."},{"key":"10.1016\/j.vetpar.2026.110697_bib7","first-page":"44","article-title":"The Enhancing Effect of Bacterial Zinc Nanoparticles on Performance, Immune Response, and Microbial Load of Nile Tilapia (Oreochromis niloticus) by Reducing the Infection by Trichodina heterodentata","author":"Alsulami","year":"2024","journal-title":"Pak. Vet. J."},{"key":"10.1016\/j.vetpar.2026.110697_bib8","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/jvp.12735","article-title":"Use of praziquantel to control platyhelminth parasites of fish","volume":"42","author":"Bader","year":"2019","journal-title":"J. Vet. Pharmacol. Ther."},{"key":"10.1016\/j.vetpar.2026.110697_bib9","article-title":"Protective Effects of Moringa oleifera Leaf Extract against Silver Nanoparticles and Arsenic Induced Hepatotoxicity in Rats","volume":"44","author":"Bashir","year":"2024","journal-title":"Pak. Vet. J."},{"key":"10.1016\/j.vetpar.2026.110697_bib10","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1017\/S0031182017001068","article-title":"A morphological and molecular study of Clinostomid metacercariae from African fish with a redescription of Clinostomum tilapiae","volume":"144","author":"Caffara","year":"2017","journal-title":"Parasitology"},{"key":"10.1016\/j.vetpar.2026.110697_bib11","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1007\/s00436-019-06586-2","article-title":"A new species of Clinostomum Leidy, 1856 based on molecular and morphological analysis of metacercariae from African siluriform fishes","volume":"119","author":"Caffara","year":"2020","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.vetpar.2026.110697_bib12","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1645\/GE-159R","article-title":"Clinostomum complanatum and Clinostomum marginatum (Rudolphi, 1819)(Digenea: Clinostomidae) are separate species based on differences in ribosomal DNA","volume":"90","author":"Dzikowski","year":"2004","journal-title":"J. Parasitol."},{"key":"10.1016\/j.vetpar.2026.110697_bib13","doi-asserted-by":"crossref","first-page":"237","DOI":"10.54203\/scil.2022.wvj30","article-title":"Improved Dot-ELISA assay using purified Sheep Coenurus cerebralis antigenic fractions for the diagnosis of Zoonotic Coenurosis","volume":"12","author":"El Akkad","year":"2022","journal-title":"World Vet. J."},{"key":"10.1016\/j.vetpar.2026.110697_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.exppara.2023.108650","article-title":"A smart economic way to control camel parasites and improve camel production in Egypt","volume":"255","author":"El-Bahy","year":"2023","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.vetpar.2026.110697_bib15","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1467460","article-title":"Essential oils as capsule disruptors: enhancing antibiotic efficacy against multidrug-resistant Klebsiella pneumoniae","volume":"15","author":"El-Demerdash","year":"2024","journal-title":"Front. Microbiol"},{"key":"10.1016\/j.vetpar.2026.110697_bib16","article-title":"Hippobosca equina: Influences on oxidative stress and immune\u2010regulating cytokine responses in horses","author":"El-Geneady","year":"2025","journal-title":"Med. Vet. Entomol."},{"key":"10.1016\/j.vetpar.2026.110697_bib17","doi-asserted-by":"crossref","first-page":"877","DOI":"10.33899\/ijvs.2022.132430.2094","article-title":"Effect of garlic oil nanoemulsion against multidrug resistant Pseudomonas aeruginosa isolated from broiler","volume":"36","author":"El-Oksh","year":"2022","journal-title":"Iraqi J. Vet. Sci."},{"key":"10.1016\/j.vetpar.2026.110697_bib18","first-page":"673","article-title":"Licochalcone A, a licorice flavonoid: Antioxidant, cytotoxic, genotoxic, and chemopreventive potential. J. Toxicol. Environ. Health A","volume":"83","author":"de Freitas","year":"2020"},{"key":"10.1016\/j.vetpar.2026.110697_bib19","doi-asserted-by":"crossref","first-page":"5165","DOI":"10.3390\/molecules27165165","article-title":"Date Fruit (Phoenix dactylifera L.) Cultivar Extracts: Nanoparticle Synthesis, Antimicrobial and Antioxidant Activities","volume":"27","author":"Halabi","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.vetpar.2026.110697_bib20","first-page":"44","article-title":"Nanoparticles as Potent Allies in Combating Antibiotic Resistance: A Promising Frontier in Antimicrobial Therapy","author":"Hannan","year":"2024","journal-title":"Pak. Vet. J."},{"key":"10.1016\/j.vetpar.2026.110697_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2023.113969","article-title":"Novel landmarks on the journey from natural products to pharmaceutical formulations: Phytochemical, biological, toxicological and computational activities of Satureja hortensis L","volume":"179","author":"Huwaimel","year":"2023","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.vetpar.2026.110697_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2025.110440","article-title":"Smart application of silver nanoparticles in the treatment of chicken coccidiosis in combination with special supplement to alleviate its toxicity","volume":"336","author":"Khalifa","year":"2025","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2026.110697_bib23","doi-asserted-by":"crossref","first-page":"3188","DOI":"10.1021\/acs.molpharmaceut.9b00390","article-title":"Glycyrrhizin-assisted transport of praziquantel anthelmintic drug through the lipid membrane: An experiment and MD simulation","volume":"16","author":"Kim","year":"2019","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.vetpar.2026.110697_bib24","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.aquaculture.2018.05.052","article-title":"The discovery of Clinostomum complanatum metacercariae in farmed Chinese sucker, Myxocyprinus asiaticus","volume":"495","author":"Li","year":"2018","journal-title":"Aquaculture"},{"key":"10.1016\/j.vetpar.2026.110697_bib25","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1051\/parasite\/2021060","article-title":"In vitro anthelmintic activity of an aqueous extract of Glycyrrhiza glabra and of glycyrrhetinic acid against gastrointestinal nematodes of small ruminants","volume":"28","author":"Maestrini","year":"2021","journal-title":"Parasite"},{"key":"10.1016\/j.vetpar.2026.110697_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2023\/5579508","article-title":"Molecular characterization and immunological approaches associated with yellow grub trematode (clinostomid) infecting Nile Tilapia","volume":"2023","author":"Mahdy","year":"2023","journal-title":"Aquac. Res."},{"key":"10.1016\/j.vetpar.2026.110697_bib27","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1186\/s12917-024-04226-1","article-title":"Innovative molecular and immunological approaches of heterophyiasis infecting some Egyptian marketed fishes","volume":"20","author":"Mahdy","year":"2024","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.vetpar.2026.110697_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.rvsc.2024.105239","article-title":"Immunological and molecular evaluation of zoonotic metacercarial infection in freshwater fish: a cross-sectional analysis","volume":"172","author":"Mahdy","year":"2024","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.vetpar.2026.110697_bib29","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-74846-y","article-title":"An innovative approach to control fish-borne zoonotic metacercarial infections in aquaculture by utilizing nanoparticles","volume":"14","author":"Mahdy","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.vetpar.2026.110697_bib30","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3390\/molecules28020661","article-title":"Nanotechnology: a revolution in modern industry","volume":"28","author":"Malik","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.vetpar.2026.110697_bib31","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. immun. method"},{"key":"10.1016\/j.vetpar.2026.110697_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/futurepharmacol2010001","article-title":"Exploring the pharmacological potential of glycyrrhizic acid: From therapeutic applications to trends in nanomedicine","volume":"2","author":"Nascimento","year":"2022","journal-title":"Future Pharm."},{"key":"10.1016\/j.vetpar.2026.110697_bib33","first-page":"123","article-title":"Study effect of date seeds powder on female rats","volume":"29","author":"Rahman","year":"2019","journal-title":"J. Home Econ. Menou Univ."},{"key":"10.1016\/j.vetpar.2026.110697_bib34","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1186\/s13071-024-06564-3","article-title":"Novel insights into antioxidant status, gene expression, and immunohistochemistry in an animal model infected with camel-derived Trypanosoma evansi and Theileria annulata","volume":"17","author":"Ramadan","year":"2024","journal-title":"Parasites Vectors"},{"key":"10.1016\/j.vetpar.2026.110697_bib35","doi-asserted-by":"crossref","DOI":"10.1007\/s12639-020-01309-2","article-title":"Animal hydatid cyst genotypes as a potential substitute for human hydatid cyst as a source of antigen for diagnosis of zoonotichydatidosis","author":"Ramadan","year":"2021","journal-title":"J. Parasit. Dis."},{"key":"10.1016\/j.vetpar.2026.110697_bib36","first-page":"421","article-title":"The use of Giardia immunogenic protein fraction to distinguish assemblages in humans and animals","volume":"10","author":"Ramadan","year":"2020","journal-title":"World Vet. J."},{"key":"10.1016\/j.vetpar.2026.110697_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0303702","article-title":"Novel insights into immune stress markers associated with myxosporeans gill infection in Nile tilapia (molecular and immunohistochemical studies)","author":"Ramadan","year":"2024","journal-title":"PLoS One"},{"key":"10.1016\/j.vetpar.2026.110697_bib38","doi-asserted-by":"crossref","first-page":"329","DOI":"10.14202\/vetworld.2025.329-340","article-title":"Targeted pre-partum strategies to suppress Toxocara vitulorum hypobiotic larvae: Reducing transmission to calves and genotypic insights into buffalo infections","author":"Ramadan","year":"2025","journal-title":"Vet. World 18"},{"key":"10.1016\/j.vetpar.2026.110697_bib39","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.17582\/journal.aavs\/2022\/10.10.2186.2196","article-title":"Synthesis, characterization and investigation of the anti-coccidial activity of new formulation curcumin-olive oil nano-composite","volume":"10","author":"Ramadan","year":"2022","journal-title":"Adv. Anim. Vet. Sci."},{"key":"10.1016\/j.vetpar.2026.110697_bib40","doi-asserted-by":"crossref","first-page":"2966","DOI":"10.3390\/nano12172966","article-title":"Nematicidal Potential of Green Silver Nanoparticles Synthesized Using Aqueous Root Extract of Glycyrrhiza glabra","volume":"12","author":"Rani","year":"2022","journal-title":"Nanomaterials"},{"key":"10.1016\/j.vetpar.2026.110697_bib41","doi-asserted-by":"crossref","first-page":"276","DOI":"10.37290\/ctnr2641-452X.17:276-281","article-title":"Anthelmintic Effect of Date Palm Fruit: A Systematic Review.","volume":"17","author":"Rauf","year":"2018","journal-title":"Curr. Top. Nutraceut. Res."},{"key":"10.1016\/j.vetpar.2026.110697_bib42","doi-asserted-by":"crossref","DOI":"10.1186\/s13071-025-06970-1","article-title":"Innovative diagnostic strategies for equine habronemiasis: exploring molecular identification, gene expression, and oxidative stress markers","author":"Salem","year":"2025","journal-title":"Parasites Vectors"},{"key":"10.1016\/j.vetpar.2026.110697_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2025.110567","article-title":"Innovative diagnostic strategies for Taenia ovis infection: exploring molecular, gene expression, oxidative stress, and histopathological insights","author":"Salem","year":"2025","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2026.110697_bib44","article-title":"Molecular and pathological insights into gene expression and oxidative stress in\u00a0Clinostomum complanatum\u00a0and\u00a0Euclinostomum heterostomum","author":"Salem","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.vetpar.2026.110697_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2025.110584","article-title":"First report of Astragalus polysaccharide nanoemulsion efficacy against clinostomid metacercariae in Nile tilapia","author":"Salem","year":"2025","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.vetpar.2026.110697_bib46","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1111\/raq.12356","article-title":"Advances in nanotechnology for sustainable aquaculture and fisheries","volume":"12","author":"Shah","year":"2020","journal-title":"Rev. Aquac."},{"key":"10.1016\/j.vetpar.2026.110697_bib47","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1515\/aopf-2015-0015","article-title":"Studies on the epidemiology and histopathology of Euclinostomum heterostomum (Trematoda; Digenea) infection in Channa punctata from North India","volume":"23","author":"Shareef","year":"2015","journal-title":"Arch. Pol. Fish."},{"key":"10.1016\/j.vetpar.2026.110697_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2021.728250","article-title":"Genotoxic potential of nanoparticles: structural and functional modifications in DNA","volume":"12","author":"Shukla","year":"2021","journal-title":"Front. Genet"},{"key":"10.1016\/j.vetpar.2026.110697_bib49","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/0014-4827(88)90265-0","article-title":"A simple technique for quantitation of low levels of DNA damage in individual cells","volume":"175","author":"Singh","year":"1988","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.vetpar.2026.110697_bib50","article-title":"Awareness of parasitic zoonotic diseases among pet owners in Cairo, Egypt","volume":"51","author":"Taha","year":"2024","journal-title":"Vet. Parasitol. Reg. Stud. Rep."},{"key":"10.1016\/j.vetpar.2026.110697_bib51","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s12917-025-04616-z","article-title":"Multifaceted analysis of equine cystic echinococcosis: genotyping, immunopathology, and screening of repurposed drugs against E. equinus protoscolices","volume":"21","author":"Taha","year":"2025","journal-title":"BMC Vet. Res."}],"container-title":["Veterinary Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401726000130?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304401726000130?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T00:16:26Z","timestamp":1772842586000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304401726000130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":51,"alternative-id":["S0304401726000130"],"URL":"https:\/\/doi.org\/10.1016\/j.vetpar.2026.110697","relation":{},"ISSN":["0304-4017"],"issn-type":[{"value":"0304-4017","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Date seed\u2013and licorice\u2013derived nanoemulsions inhibit clinostomid metacercariae recovered from naturally infected Nile tilapia (Oreochromis niloticus): First report","name":"articletitle","label":"Article Title"},{"value":"Veterinary Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vetpar.2026.110697","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110697"}}