{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:07:54Z","timestamp":1785888474402,"version":"3.56.0"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["valuehealthregionalissues.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Value in Health Regional Issues"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.vhri.2021.09.006","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T13:29:52Z","timestamp":1637328592000},"page":"53-59","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Cost-Effectiveness Analysis of the Implementation of Cryptococcal Antigen Lateral Flow Assay for the Diagnosis of Cryptococcal Meningitis in Symptomatic People Living With Human Immunodeficiency Virus in Brazil"],"prefix":"10.1016","volume":"29","author":[{"given":"Cid Manso de Mello","family":"Vianna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela Bittencourt Gonzalez","family":"Mosegui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.vhri.2021.09.006_bib1","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1097\/QAD.0b013e328322ffac","article-title":"Estimation of the current global burden of cryptococcal meningitis among persons living with HIV\/AIDS","volume":"23","author":"Park","year":"2009","journal-title":"AIDS"},{"issue":"6","key":"10.1016\/j.vhri.2021.09.006_bib2","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1590\/S0036-46652003000600001","article-title":"Cryptococcosis: a review of the Brazilian experience for the disease","volume":"45","author":"Pappalardo","year":"2003","journal-title":"Rev Inst Med Trop S Paulo"},{"issue":"1","key":"10.1016\/j.vhri.2021.09.006_bib3","doi-asserted-by":"crossref","first-page":"169","DOI":"10.2147\/CLEP.S38850","article-title":"Cryptococcal meningitis: epidemiology and therapeutic options","volume":"6","author":"Sloan","year":"2014","journal-title":"Clin Epidemiol"},{"issue":"8","key":"10.1016\/j.vhri.2021.09.006_bib4","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S1473-3099(17)30243-8","article-title":"Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis","volume":"17","author":"Rajasingham","year":"2017","journal-title":"Lancet Infect Dis"},{"issue":"suppl 19","key":"10.1016\/j.vhri.2021.09.006_bib5","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1590\/S0036-46652015000700008","article-title":"Lateral flow assay for cryptococcal antigen: an important advance to improve the continuum of HIV care and reduce cryptococcal meningitis-related mortality","volume":"57","author":"Vidal","year":"2015","journal-title":"Rev Inst Med Trop S Paulo"},{"issue":"7","key":"10.1016\/j.vhri.2021.09.006_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0007569","article-title":"Mortality by cryptococcosis in Brazil from 2000 to 2012: a descriptive epidemiological study","volume":"13","author":"Alves Soares","year":"2019","journal-title":"PLoS Negl Trop Dis"},{"issue":"5","key":"10.1016\/j.vhri.2021.09.006_bib9","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1590\/S0037-86822008000500022","article-title":"Consensus on cryptococcosis\u20132008","volume":"41","author":"de Criptococose","year":"2008","journal-title":"Rev Soc Bras Med Trop"},{"issue":"1","key":"10.1016\/j.vhri.2021.09.006_bib11","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1186\/s12879-017-2325-9","article-title":"Cost-effectiveness of CRAG-LFA screening for cryptococcal meningitis among people living with HIV in Uganda","volume":"17","author":"Ramachandran","year":"2017","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.vhri.2021.09.006_bib12","doi-asserted-by":"crossref","first-page":"144","DOI":"10.12688\/wellcomeopenres.15464.2","article-title":"Cost-effectiveness of reflex laboratory-based cryptococcal antigen screening for the prevention and treatment of cryptococcal meningitis in Botswana","volume":"4","author":"Tenforde","year":"2020","journal-title":"Wellcome Open Res"},{"issue":"16","key":"10.1016\/j.vhri.2021.09.006_bib13","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1097\/QAD.0b013e3282a4a64d","article-title":"HIV-associated cryptococcal meningitis","volume":"21","author":"Jarvis","year":"2007","journal-title":"AIDS"},{"issue":"7","key":"10.1016\/j.vhri.2021.09.006_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0069288","article-title":"Cost effectiveness of cryptococcal antigen screening as a strategy to prevent HIV-associated cryptococcal meningitis in South Africa","volume":"8","author":"Jarvis","year":"2013","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.vhri.2021.09.006_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0210105","article-title":"Evaluation of a national cryptococcal antigen screening program for HIV-infected patients in Uganda: a cost-effectiveness modeling analysis","volume":"14","author":"Rajasingham","year":"2019","journal-title":"PLoS One"},{"issue":"31","key":"10.1016\/j.vhri.2021.09.006_bib16","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000011722","article-title":"A\u00a0qualitative evaluation of an implementation study for cryptococcal antigen screening and treatment in Uganda","volume":"97","author":"Lofgren","year":"2018","journal-title":"Medicine (Baltimore)"},{"issue":"5","key":"10.1016\/j.vhri.2021.09.006_bib17","doi-asserted-by":"crossref","first-page":"e85","DOI":"10.1097\/QAI.0b013e31824c837e","article-title":"Integrating cryptococcal antigen screening and pre-emptive treatment into routine HIV care","volume":"59","author":"Rajasingham","year":"2012","journal-title":"J\u00a0Acquir Immune Defic Syndr"},{"issue":"2","key":"10.1016\/j.vhri.2021.09.006_bib18","doi-asserted-by":"crossref","first-page":"e37","DOI":"10.1097\/QAI.0000000000000976","article-title":"Evaluation of a public-sector, provider-initiated cryptococcal antigen screening and treatment program, Western Cape, South Africa","volume":"72","author":"Vallabhaneni","year":"2016","journal-title":"J\u00a0Acquir Immune Defic Syndr"},{"issue":"4","key":"10.1016\/j.vhri.2021.09.006_bib19","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1086\/655143","article-title":"Cost-effectiveness of serum cryptococcal antigen screening to prevent deaths among HIV-infected persons with a CD4+ cell count < or\u00a0= 100 cells\/microL who start HIV therapy in resource-limited settings","volume":"51","author":"Meya","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.vhri.2021.09.006_bib27","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s12879-020-4798-1","article-title":"Cryptococcal antigenemia is associated with meningitis or death in HIV-infected adults with CD4 100-200 cells\/mm3","volume":"20","author":"Wykowski","year":"2020","journal-title":"BMC Infect Dis"},{"issue":"10","key":"10.1016\/j.vhri.2021.09.006_bib28","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1093\/cid\/cir613","article-title":"Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis","volume":"53","author":"Jarvis","year":"2011","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.vhri.2021.09.006_bib29","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3201\/eid2001.130906","article-title":"Multisite validation of cryptococcal antigen lateral flow assay and quantification by laser thermal contrast","volume":"20","author":"Boulware","year":"2014","journal-title":"Emerg Infect Dis"},{"issue":"4","key":"10.1016\/j.vhri.2021.09.006_bib30","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0062213","article-title":"Prevalence of Cryptococcal antigenemia and Cost-effectiveness of a cryptococcal antigen screening program--Vietnam","volume":"8","author":"Smith","year":"2013","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.vhri.2021.09.006_bib31","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1093\/cid\/ciaa1243","article-title":"Cryptococcal antigen in serum and cerebrospinal fluid for detecting cryptococcal meningitis in adults living with human immunodeficiency virus: systematic review and meta-analysis of diagnostic test accuracy studies","volume":"72","author":"Temfack","year":"2021","journal-title":"Clin Infect Dis"}],"container-title":["Value in Health Regional Issues"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212109921001400?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212109921001400?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T20:12:45Z","timestamp":1761941565000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212109921001400"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":21,"alternative-id":["S2212109921001400"],"URL":"https:\/\/doi.org\/10.1016\/j.vhri.2021.09.006","relation":{},"ISSN":["2212-1099"],"issn-type":[{"value":"2212-1099","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cost-Effectiveness Analysis of the Implementation of Cryptococcal Antigen Lateral Flow Assay for the Diagnosis of Cryptococcal Meningitis in Symptomatic People Living With Human Immunodeficiency Virus in Brazil","name":"articletitle","label":"Article Title"},{"value":"Value in Health Regional Issues","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vhri.2021.09.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 ISPOR--The professional society for health economics and outcomes research. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}