{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T21:09:18Z","timestamp":1788988158530,"version":"build-2803163510"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["U54GM115677"],"award-info":[{"award-number":["U54GM115677"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006090","name":"Center for Global Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006090","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["K43TW010684"],"award-info":[{"award-number":["K43TW010684"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["valuehealthregionalissues.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Value in Health Regional Issues"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.vhri.2025.101129","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T17:28:02Z","timestamp":1747848482000},"page":"101129","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Cost-Effectiveness of an Enhanced Patient Care Intervention for Improving Viral Suppression Among Kenyan Adults Living With HIV"],"prefix":"10.1016","volume":"49","author":[{"given":"Jenna","family":"Fritz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juddy","family":"Wachira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Wilson-Barthes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Kafu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Chemtai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Becky","family":"Genberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Gal\u00e1rraga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vhri.2025.101129_bib1","author":"HIV"},{"key":"10.1016\/j.vhri.2025.101129_bib4","series-title":"Costing the Implementation of the 2016 HIV Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection in Kenya;","year":"2017"},{"key":"10.1016\/j.vhri.2025.101129_bib5","author":"Kates"},{"issue":"5","key":"10.1016\/j.vhri.2025.101129_bib7","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/tmi.13746","article-title":"Systematic review: development of a person-centered care framework within the context of HIV treatment settings in sub-Saharan Africa","volume":"27","author":"Duffy","year":"2022","journal-title":"Trop Med Int Heal"},{"issue":"4","key":"10.1016\/j.vhri.2025.101129_bib8","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1177\/1077558712465774","article-title":"Patient-centered care and outcomes: a systematic review of the literature","volume":"70","author":"Rathert","year":"2013","journal-title":"Med Care Res Rev"},{"issue":"1","key":"10.1016\/j.vhri.2025.101129_bib9","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/s12954-019-0347-x","article-title":"A client-centered relational framework on barriers to the integration of HIV and substance use services: a systematic review","volume":"16","author":"Pinto","year":"2019","journal-title":"Harm Reduct J"},{"issue":"7","key":"10.1016\/j.vhri.2025.101129_bib10","article-title":"Multiplexed technologies for sexually transmitted infections: global evidence on patient-centered and clinical health outcomes","volume":"6","author":"Naeem","year":"2021","journal-title":"BMJ Glob Heal"},{"issue":"3","key":"10.1016\/j.vhri.2025.101129_bib12","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0212656","article-title":"Empowering HIV-infected women in low-resource settings: a pilot study evaluating a patient-centered HIV prevention strategy for reproduction","volume":"14","author":"Mmeje","year":"2019","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.vhri.2025.101129_bib13","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/COH.0000000000000770","article-title":"Promoting patient-centered care within HIV care settings in sub-Saharan Africa","volume":"18","author":"Wachira","year":"2023","journal-title":"Curr Opin HIV AIDS"},{"issue":"7","key":"10.1016\/j.vhri.2025.101129_bib14","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2021-054386","article-title":"A systematic review of impact of person-centred interventions for serious physical illness in terms of outcomes and costs","volume":"12","author":"Nkhoma","year":"2022","journal-title":"BMJ Open"},{"issue":"3","key":"10.1016\/j.vhri.2025.101129_bib15","doi-asserted-by":"crossref","first-page":"e48","DOI":"10.1097\/QAI.0000000000002458","article-title":"Costs and cost-effectiveness of the patient-centered HIV care model: a collaboration between community-based pharmacists and primary medical providers","volume":"85","author":"Shrestha","year":"2020","journal-title":"JAIDS J Acquir Immune Defic Syndr"},{"issue":"9","key":"10.1016\/j.vhri.2025.101129_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1003803","article-title":"Effect of a patient-centered hypertension delivery strategy on all-cause mortality: secondary analysis of SEARCH, a community-randomized trial in rural Kenya and Uganda","volume":"18","author":"Hickey","year":"2021","journal-title":"PLoS Med"},{"issue":"1","key":"10.1016\/j.vhri.2025.101129_bib17","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s40249-023-01116-w","article-title":"Cost of treatment support for multidrug-resistant tuberculosis using patient-centred approaches in Ethiopia: a model-based method","volume":"12","author":"Rosu","year":"2023","journal-title":"Infect Dis Pover"},{"issue":"11","key":"10.1016\/j.vhri.2025.101129_bib18","doi-asserted-by":"crossref","first-page":"963","DOI":"10.2165\/11318230-000000000-00000","article-title":"Cost effectiveness of facility-based care, Home-Based Care and Mobile Clinics for Provision of Antiretroviral Therapy in Uganda","volume":"27","author":"Babigumira","year":"2009","journal-title":"Pharmacoeconomics"},{"issue":"4","key":"10.1016\/j.vhri.2025.101129_bib19","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1097\/QAI.0000000000002987","article-title":"Impact of an enhanced Patient Care intervention on viral suppression among patients living with HIV in Kenya","volume":"90","author":"Wachira","year":"2022","journal-title":"JAIDS J Acquir Immune Defic Syndr"},{"key":"10.1016\/j.vhri.2025.101129_bib20","author":"Mcintosh"},{"issue":"1","key":"10.1016\/j.vhri.2025.101129_bib21","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s12992-018-0366-5","article-title":"Leveraging the power of partnerships: spreading the vision for a population health care delivery model in western Kenya","volume":"14","author":"Mercer","year":"2018","journal-title":"Global Health"},{"issue":"4","key":"10.1016\/j.vhri.2025.101129_bib22","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.pec.2016.10.029","article-title":"An integrative review of the efficacy of motivational interviewing in HIV management","author":"Dillard","year":"2017","journal-title":"Patient Educ Couns"},{"issue":"15","key":"10.1016\/j.vhri.2025.101129_bib23","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1097\/QAD.0000000000001958","article-title":"Costs of streamlined HIV care delivery in rural Ugandan and Kenyan clinics in the SEARCH Study","volume":"32","author":"Shade","year":"2018","journal-title":"AIDS"},{"key":"10.1016\/j.vhri.2025.101129_bib24","author":"Moreland"},{"issue":"1","key":"10.1016\/j.vhri.2025.101129_bib25","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/hpm.2905","article-title":"Patient costs of diabetes mellitus care in public health care facilities in Kenya","volume":"35","author":"Oyando","year":"2020","journal-title":"Int J Health Plann Manage"},{"issue":"11","key":"10.1016\/j.vhri.2025.101129_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0225194","article-title":"Patient-level cost of home- and facility-based child pneumonia treatment in Suba Sub County, Kenya","volume":"14","author":"Machuki","year":"2019","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.vhri.2025.101129_bib27","doi-asserted-by":"crossref","first-page":"e116","DOI":"10.1016\/S2352-3018(18)30317-5","article-title":"Risks and benefits of dolutegravir-based antiretroviral drug regimens in sub-Saharan Africa: a modelling study","volume":"6","author":"Phillips","year":"2019","journal-title":"Lancet HIV"},{"issue":"11","key":"10.1016\/j.vhri.2025.101129_bib28","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1097\/QAD.0b013e32832b7dca","article-title":"Sexual transmission of HIV according to viral load and antiretroviral therapy: systematic review and meta-analysis","volume":"23","author":"Attia","year":"2009","journal-title":"AIDS"},{"issue":"1","key":"10.1016\/j.vhri.2025.101129_bib29","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/1471-2458-5-130","article-title":"Cost, affordability and cost-effectiveness of strategies to control tuberculosis in countries with high HIV prevalence","volume":"5","author":"Currie","year":"2005","journal-title":"BMC Public Health"},{"issue":"2","key":"10.1016\/j.vhri.2025.101129_bib31","doi-asserted-by":"crossref","first-page":"143","DOI":"10.26719\/2020.26.2.143","article-title":"Analysis of life expectancy across countries using a decision tree","volume":"26","author":"Karacan","year":"2020","journal-title":"East Mediterr Heal J"},{"issue":"1","key":"10.1016\/j.vhri.2025.101129_bib32","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1080\/09540121.2019.1612021","article-title":"Epidemiological profile of individuals diagnosed with HIV: results from the preliminary phase of case-based surveillance in Kenya","volume":"32","author":"Harklerodea","year":"2020","journal-title":"AIDS Care"},{"issue":"12","key":"10.1016\/j.vhri.2025.101129_bib34","doi-asserted-by":"crossref","first-page":"925","DOI":"10.2471\/BLT.15.164418","article-title":"Cost-effectiveness thresholds: pros and cons","volume":"94","author":"Bertram","year":"2016","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.vhri.2025.101129_bib35","author":"Ochalek"},{"issue":"8","key":"10.1016\/j.vhri.2025.101129_bib36","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.jval.2016.02.017","article-title":"Country-level cost-effectiveness thresholds: initial estimates and the need for further research","volume":"19","author":"Woods","year":"2016","journal-title":"Value Health"},{"issue":"3","key":"10.1016\/j.vhri.2025.101129_bib37","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.jval.2021.08.014","article-title":"The use of cost-effectiveness thresholds for evaluating health interventions in low- and middle-income countries from 2015 to 2020: a review","volume":"25","author":"Kazibwe","year":"2022","journal-title":"Value Health"},{"key":"10.1016\/j.vhri.2025.101129_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2020.100453","article-title":"Modeling the health impact and cost threshold of long-acting ART for adolescents and young adults in Kenya","volume":"25","author":"Culhane","year":"2020","journal-title":"EClinicalmedicine"},{"issue":"6","key":"10.1016\/j.vhri.2025.101129_bib39","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1093\/ije\/dyg302","article-title":"Prevention Effectiveness: a guide to decision analysis and economic evaluation","volume":"32","author":"Zwahlen","year":"2003","journal-title":"Int J Epidemiol"},{"issue":"25","key":"10.1016\/j.vhri.2025.101129_bib40","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1016\/j.jacc.2008.09.018","article-title":"Interpreting the results of cost-effectiveness studies","volume":"52","author":"Cohen","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.vhri.2025.101129_bib41","series-title":"Methods for the Economic Evaluation of Health Care Programmes","author":"Drummond","year":"2005"},{"issue":"suppl 1","key":"10.1016\/j.vhri.2025.101129_bib42","doi-asserted-by":"crossref","first-page":"S93","DOI":"10.1097\/QAD.0000000000002183","article-title":"Evaluating a patient-centred intervention to increase disclosure and promote resilience for children living with HIV in Kenya","volume":"33","author":"Vreeman","year":"2019","journal-title":"AIDS"},{"issue":"4","key":"10.1016\/j.vhri.2025.101129_bib43","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1097\/QAI.0000000000003205","article-title":"The clinical impact and cost-effectiveness of clinic-based cognitive behavioral therapy for people with HIV, depression, and virologic failure in South Africa","volume":"93","author":"Gandhi","year":"2023","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"4","key":"10.1016\/j.vhri.2025.101129_bib44","doi-asserted-by":"crossref","first-page":"e216","DOI":"10.1016\/S2352-3018(20)30279-4","article-title":"Cost-effectiveness of point-of-care testing with task-shifting for HIV care in South Africa: a modelling study","volume":"8","author":"Sharma","year":"2021","journal-title":"Lancet HIV"},{"issue":"5","key":"10.1016\/j.vhri.2025.101129_bib45","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/QAI.0000000000001956","article-title":"Cost-effectiveness of accelerated HIV response scenarios in C\u00f4te d\u2019Ivoire","volume":"80","author":"Maheu-Giroux","year":"2019","journal-title":"JAIDS J Acquir Immune Defic Syndr"},{"issue":"2","key":"10.1016\/j.vhri.2025.101129_bib46","doi-asserted-by":"crossref","DOI":"10.1002\/jia2.25875","article-title":"Incremental costs of integrated PrEP provision and effective use counselling in community-based platforms for adolescent girls and young women in South Africa: an observational study","volume":"25","author":"Mudimu","year":"2022","journal-title":"J Int AIDS Soc"},{"issue":"7","key":"10.1016\/j.vhri.2025.101129_bib47","doi-asserted-by":"crossref","DOI":"10.2196\/mhealth.9493","article-title":"Health care provider utilization and cost of an mHealth intervention in vulnerable people living with HIV in Vancouver, Canada: prospective study","volume":"6","author":"Campbell","year":"2018","journal-title":"JMIR Mhealth Uhealth"},{"issue":"5","key":"10.1016\/j.vhri.2025.101129_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0194305","article-title":"Explaining the heterogeneity in average costs per HIV\/AIDS patient in Nigeria: the role of supply-side and service delivery characteristics","volume":"13","author":"Bautista-Arredondo","year":"2018","journal-title":"PLoS One"}],"container-title":["Value in Health Regional Issues"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212109925000548?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212109925000548?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T20:34:53Z","timestamp":1788986093000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212109925000548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":42,"alternative-id":["S2212109925000548"],"URL":"https:\/\/doi.org\/10.1016\/j.vhri.2025.101129","relation":{},"ISSN":["2212-1099"],"issn-type":[{"value":"2212-1099","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cost-Effectiveness of an Enhanced Patient Care Intervention for Improving Viral Suppression Among Kenyan Adults Living With HIV","name":"articletitle","label":"Article Title"},{"value":"Value in Health Regional Issues","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vhri.2025.101129","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of International Society for Pharmacoeconomics and Outcomes Research, Inc.","name":"copyright","label":"Copyright"}],"article-number":"101129"}}