{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:50:05Z","timestamp":1790895005292,"version":"4.1.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":3461,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2004,3]]},"DOI":"10.1016\/j.virol.2003.12.013","type":"journal-article","created":{"date-parts":[[2004,2,28]],"date-time":"2004-02-28T06:37:41Z","timestamp":1077950261000},"page":"134-143","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"title":["Old and New World arenaviruses share a highly conserved epitope in the fusion domain of the glycoprotein 2, which is recognized by Lassa virus-specific human CD4+ T-cell clones"],"prefix":"10.1016","volume":"321","author":[{"given":"Jan ter","family":"Meulen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlis","family":"Badusche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Satoguina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Strecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Lenz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelius","family":"Loeliger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Sakho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kekoura","family":"Koulemou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamine","family":"Koivogui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Achim","family":"Hoerauf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virol.2003.12.013_BIB1","doi-asserted-by":"crossref","first-page":"6992","DOI":"10.1128\/JVI.74.15.6992-7004.2000","article-title":"Genetic diversity among Lassa virus strains","volume":"74","author":"Bowen","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2003.12.013_BIB3","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/S0006-291X(02)02053-3","article-title":"Phylogeny of New World arenaviruses based on the complete coding sequences of the small genomic segment identified an evolutionary lineage produced by intrasegmental recombination","volume":"296","author":"Charrel","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.virol.2003.12.013_BIB2","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1006\/jmbi.2001.5016","article-title":"Zooming in on the hydrophobic ridge of H-2Db: implications for the conformational variability of bound peptides","volume":"312","author":"Ciatto","year":"2001","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.virol.2003.12.013_BIB6","first-page":"472","article-title":"Frequent detection of human papillomavirus 16 E2-specific T-helper immunity in healthy subjects","volume":"62","author":"de Jong","year":"2002","journal-title":"Cancer Res."},{"key":"10.1016\/j.virol.2003.12.013_BIB4","doi-asserted-by":"crossref","first-page":"6011","DOI":"10.1128\/jvi.71.8.6011-6019.1997","article-title":"Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute Hepatitis C virus infection","volume":"71","author":"Diepolder","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2003.12.013_BIB5","first-page":"103","article-title":"Mucosal immunization with Salmonella typhimurium expressing Lassa virus nucleocapsid protein cross-protects mice from lethal challenge with lymphocytic choriomeningitis virus","volume":"4","author":"Djavani","year":"2001","journal-title":"J. Hum. Virol."},{"key":"10.1016\/j.virol.2003.12.013_BIB7","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1744-313X.1991.tb00005.x","article-title":"HLA-DR, DQ and DP typing using PCR amplification and immobilized probes","volume":"18","author":"Erlich","year":"1991","journal-title":"Eur. J. Immunogenet."},{"key":"10.1016\/j.virol.2003.12.013_BIB8","doi-asserted-by":"crossref","first-page":"6777","DOI":"10.1128\/JVI.74.15.6777-6783.2000","article-title":"Effective vaccine for Lassa fever","volume":"74","author":"Fisher-Hoch","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2003.12.013_BIB9","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0014-5793(90)81140-J","article-title":"Prediction of arenavirus fusion peptides on the basis of computer analysis of envelope protein sequences","volume":"269","author":"Glushakova","year":"1990","journal-title":"FEBS"},{"key":"10.1016\/j.virol.2003.12.013_BIB10","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/BF02122441","article-title":"Serology and virulence diversity among Old-World arenaviruses, and the relevance to vaccine development","volume":"175","author":"Jahrling","year":"1986","journal-title":"Med. Microbiol. Immunol."},{"key":"10.1016\/j.virol.2003.12.013_BIB11","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/0035-9203(85)90388-8","article-title":"Endemic Lassa fever in Liberia: IV. Selection of optimally effective plasma for treatment by passive immunization","volume":"79","author":"Jahrling","year":"1985","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.virol.2003.12.013_BIB12","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1093\/infdis\/155.3.456","article-title":"Clinical virology of Lassa fever in hospitalized patients","volume":"155","author":"Johnson","year":"1987","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2003.12.013_BIB13","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/S0140-6736(79)90659-7","article-title":"Protection of rhesus monkeys from Lassa virus by immunization with a closely related arenavirus","volume":"2","author":"Kiley","year":"1979","journal-title":"Lancet"},{"key":"10.1016\/j.virol.2003.12.013_BIB14","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3201\/eid0802.010164","article-title":"Public health assessment of potential biological terrorism agents","volume":"8","author":"Klotz","year":"2002","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.virol.2003.12.013_BIB15","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1006\/viro.1997.8925","article-title":"Definition of an epitope on NS3 recognized by human CD4+ cytotoxic T lymphocyte clones cross-reactive for Dengue virus types 2, 3, and 4","volume":"240","author":"Kurane","year":"1998","journal-title":"Virology"},{"key":"10.1016\/j.virol.2003.12.013_BIB16","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1002\/hep.510300435","article-title":"Conserved Hepatitis C virus sequences are highly immunogenic for CD4+ cells: implications for vaccine development","volume":"30","author":"Lamonaca","year":"1999","journal-title":"Hepatology"},{"key":"10.1016\/j.virol.2003.12.013_BIB18","doi-asserted-by":"crossref","first-page":"293","DOI":"10.4049\/jimmunol.125.1.293","article-title":"Two populations of Ia-like antigens on a human B cell line","volume":"125","author":"Lampson","year":"1980","journal-title":"J. Immunol."},{"key":"10.1016\/j.virol.2003.12.013_BIB17","doi-asserted-by":"crossref","first-page":"3497","DOI":"10.1128\/jvi.67.6.3497-3506.1993","article-title":"Cross-protection against Lymphocytic Choriomeningitis Virus mediated by a CD4+ T-cell clone specific for an envelope glycoprotein of Lassa virus","volume":"67","author":"La Posta","year":"1993","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2003.12.013_BIB19","doi-asserted-by":"crossref","first-page":"12701","DOI":"10.1073\/pnas.221447598","article-title":"The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1\/S1P","volume":"98","author":"Lenz","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.virol.2003.12.013_BIB20","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1006\/viro.2001.1259","article-title":"T cell epitopes in coxsackievirus B4 structural proteins concentrate in regions conserved between enteroviruses","volume":"293","author":"Marttila","year":"2002","journal-title":"Virology"},{"key":"10.1016\/j.virol.2003.12.013_BIB21","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1093\/infdis\/155.3.437","article-title":"A prospective study of the epidemiology and ecology of Lassa fever","volume":"155","author":"McCormick","year":"1987","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2003.12.013_BIB22","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1089\/104303402320138952","article-title":"The adenovirus capsid protein hexon contains a highly conserved human CD4+ T-cell epitope","volume":"13","author":"Olive","year":"2002","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.virol.2003.12.013_BIB23","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0198-8859(85)90333-7","article-title":"Dissection of human allostimulatory determinants with cloned T cells: stimulation inhibition by monoclonal antibodies TU 22, 34, 36, 37, 39, 43 and 58 against distinct human MHC class II molecules","volume":"12","author":"Pawelec","year":"1985","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.virol.2003.12.013_BIB24","doi-asserted-by":"crossref","first-page":"11677","DOI":"10.1128\/JVI.75.23.11677-11685.2001","article-title":"Individual and bivalent vaccines based on alphavirus replicons protect guinea pigs against infection with Lassa and Ebola viruses","volume":"75","author":"Pushko","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2003.12.013_BIB25","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1099\/0022-1317-72-3-549","article-title":"Antigenic relatedness between arenaviruses defined at the epitope level by monoclonal antibodies","volume":"72","author":"Ruo","year":"1991","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2003.12.013_BIB26","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0198-8859(01)00293-2","article-title":"African diversity from the HLA point of view: influence of genetic drift, geography, linguistics, and natural selection","volume":"62","author":"Sanchez-Mazas","year":"2001","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.virol.2003.12.013_BIB27","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1093\/bioinformatics\/17.12.1236","article-title":"ProPred: prediction of HLA-DR binding sites","volume":"17","author":"Singh","year":"2001","journal-title":"Bioinformatics"},{"key":"10.1016\/j.virol.2003.12.013_BIB28","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/9858","article-title":"Generation of tissue-specific and promiscuous HLA ligand database using DNA microarrays and virtual HLA class II matrices","volume":"17","author":"Sturniolo","year":"1999","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.virol.2003.12.013_BIB29","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1128\/JCM.36.11.3143-3148.1998","article-title":"Detection of Lassa virus antinucleoprotein immunoglobulin G (IgG) and IgM antibodies with a simple recombinant immunoblot assay for field use","volume":"36","author":"ter Meulen","year":"1998","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.virol.2003.12.013_BIB30","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1128\/JVI.74.5.2186-2192.2000","article-title":"Characterization of human CD4+ T-cell clones recognizing conserved and variable epitopes of the Lassa virus nucleoprotein","volume":"74","author":"ter Meulen","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2003.12.013_BIB31","unstructured":"The QIAexpressionist, 1992. Quiagen, Hilden, Germany."},{"key":"10.1016\/j.virol.2003.12.013_BIB32","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/jmv.1890220110","article-title":"Standardization of a plaque assay for Lassa virus","volume":"22","author":"Tomori","year":"1987","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.virol.2003.12.013_BIB33","doi-asserted-by":"crossref","first-page":"152","DOI":"10.4049\/jimmunol.162.1.152","article-title":"Identification of a coserved universal Th epitope in HIV-1 reverse transcriptase that is processed and presented to HIV-specific CD4+ T cells by at least four unrelated HLA-DR molecules","volume":"162","author":"van der Burg","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.virol.2003.12.013_BIB34","doi-asserted-by":"crossref","first-page":"4177","DOI":"10.4049\/jimmunol.162.7.4177","article-title":"Mutations in immunodominant T cell epitopes derived from the nonstructural 3 protein of Hepatitis C virus have the potential for generating escape variants that may have important consequences for T cell recognition","volume":"162","author":"Wang","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.virol.2003.12.013_BIB37","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/0042-6822(88)90616-2","article-title":"Fine mapping of a peptide sequence containing an antigenic site conserved among arenaviruses","volume":"164","author":"Weber","year":"1988","journal-title":"Virology"},{"key":"10.1016\/j.virol.2003.12.013_BIB35","doi-asserted-by":"crossref","first-page":"4195","DOI":"10.1128\/JVI.75.9.4195-4207.2001","article-title":"Identification and antigenicity of broadly cross-reactive and conserved Human Immunodeficiency Virus type 1-derived helper T-lymphocyte epitopes","volume":"75","author":"Wilson","year":"2001","journal-title":"J. Virol."},{"issue":"10","key":"10.1016\/j.virol.2003.12.013_BIB36","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/S0198-8859(01)00305-6","article-title":"Antigen, allele, and haplotype frequencies report of the ASHI minority antigens workshops: part 1, African\u2013Americans","volume":"62","author":"Zachary","year":"2001","journal-title":"Hum. Immunol."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682204000091?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682204000091?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T23:27:58Z","timestamp":1758583678000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682204000091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["S0042682204000091"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2003.12.013","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2004,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Old and New World arenaviruses share a highly conserved epitope in the fusion domain of the glycoprotein 2, which is recognized by Lassa virus-specific human CD4+ T-cell clones","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2003.12.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}