{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:03:50Z","timestamp":1790262230721,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":1142,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1016\/j.virol.2010.03.012","type":"journal-article","created":{"date-parts":[[2010,4,6]],"date-time":"2010-04-06T21:02:35Z","timestamp":1270587755000},"page":"72-82","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":76,"title":["Dosage comparison of Congo Basin and West African strains of monkeypox virus using a prairie dog animal model of systemic orthopoxvirus disease"],"prefix":"10.1016","volume":"402","author":[{"given":"Christina L.","family":"Hutson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darin S.","family":"Carroll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Self","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine M.","family":"Hughes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary","family":"Braden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria A.","family":"Olson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott K.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin L.","family":"Karem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell L.","family":"Regnery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inger K.","family":"Damon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virol.2010.03.012_bib1","doi-asserted-by":"crossref","first-page":"273","DOI":"10.4269\/ajtmh.1977.26.273","article-title":"Human poxvirus disease after smallpox eradication","volume":"26","author":"Breman","year":"1977","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.virol.2010.03.012_bib2","first-page":"165","article-title":"Human monkeypox, 1970\u201379","volume":"58","author":"Breman","year":"1980","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.virol.2010.03.012_bib3","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.virol.2005.05.030","article-title":"Virulence differences between monkeypox virus isolates from West Africa and the Congo basin","volume":"340","author":"Chen","year":"2005","journal-title":"Virology"},{"key":"10.1016\/j.virol.2010.03.012_bib4","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S1473-3099(03)00856-9","article-title":"Human monkeypox: an emerging zoonosis","volume":"4","author":"Di Giulio","year":"2004","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.virol.2010.03.012_bib5","first-page":"569","article-title":"Human monkeypox","volume":"46","author":"Foster","year":"1972","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.virol.2010.03.012_bib6","doi-asserted-by":"crossref","first-page":"434","DOI":"10.3201\/eid0703.017311","article-title":"Outbreak of human monkeypox, Democratic Republic of Congo, 1996 to 1997","volume":"7","author":"Hutin","year":"2001","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.virol.2010.03.012_bib7","doi-asserted-by":"crossref","first-page":"757","DOI":"10.4269\/ajtmh.2007.76.757","article-title":"Monkeypox zoonotic associations: insights from laboratory evaluation of animals associated with the multi-state US outbreak","volume":"76","author":"Hutson","year":"2007","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.virol.2010.03.012_bib8","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1099\/vir.0.005108-0","article-title":"A prairie dog animal model of systemic orthopoxvirus disease using West African and Congo Basin strains of monkeypox virus","volume":"90","author":"Hutson","year":"2009","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2010.03.012_bib9","doi-asserted-by":"crossref","first-page":"e8912","DOI":"10.1371\/journal.pone.0008912","article-title":"Comparison of West African and Congo Basin monkeypox viruses in BALB\/c and C57BL\/6 mice","volume":"5","author":"Hutson","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.virol.2010.03.012_bib10","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/infdis\/156.2.293","article-title":"Human monkeypox: clinical features of 282 patients","volume":"156","author":"Jezek","year":"1987","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2010.03.012_bib11","first-page":"115","article-title":"The role of squirrels in sustaining monkeypox virus transmission","volume":"39","author":"Khodakevich","year":"1987","journal-title":"Trop Geogr.Med"},{"key":"10.1016\/j.virol.2010.03.012_bib12","first-page":"56","article-title":"Monkeypox virus in relation to the ecological features surrounding human settlements in Bumba zone, Zaire","volume":"39","author":"Khodakevich","year":"1987","journal-title":"Trop. Geogr. Med."},{"key":"10.1016\/j.virol.2010.03.012_bib13","doi-asserted-by":"crossref","first-page":"428","DOI":"10.4269\/ajtmh.2005.73.428","article-title":"Extended interhuman transmission of monkeypox in a hospital community in the Republic of the Congo, 2003","volume":"73","author":"Learned","year":"2005","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.virol.2010.03.012_bib14","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jcv.2006.03.012","article-title":"Detection of monkeypox virus with real-time PCR assays","volume":"36","author":"Li","year":"2006","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.virol.2010.03.012_bib15","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1099\/vir.0.81215-0","article-title":"A tale of two clades: monkeypox viruses","volume":"86","author":"Likos","year":"2005","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2010.03.012_bib16","doi-asserted-by":"crossref","first-page":"2919","DOI":"10.1128\/JCM.40.8.2919-2921.2002","article-title":"Outbreaks of disease suspected of being due to human monkeypox virus infection in the Democratic Republic of Congo in 2001","volume":"40","author":"Meyer","year":"2002","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.virol.2010.03.012_bib17","doi-asserted-by":"crossref","first-page":"e6592","DOI":"10.1371\/journal.pone.0006592","article-title":"Comparison of monkeypox viruses pathogenesis in mice by in vivo imaging","volume":"4","author":"Osorio","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1016\/j.virol.2010.03.012_bib18","article-title":"A simple method of estimating fifty percent endpoints","volume":"27","author":"Reed","year":"1938","journal-title":"Am. J. Hyg."},{"key":"10.1016\/j.virol.2010.03.012_bib19","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1056\/NEJMoa032299","article-title":"The detection of monkeypox in humans in the Western Hemisphere","volume":"350","author":"Reed","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.virol.2010.03.012_bib20","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1086\/505880","article-title":"Clinical manifestations of human monkeypox influenced by route of infection","volume":"194","author":"Reynolds","year":"2006","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2010.03.012_bib21","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1099\/vir.0.010207-0","article-title":"Virulence and pathophysiology of the Congo Basin and West African strains of monkeypox virus in non-human primates","volume":"90","author":"Saijo","year":"2009","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2010.03.012_bib22","doi-asserted-by":"crossref","first-page":"155","DOI":"10.4269\/ajtmh.2007.76.155","article-title":"Comparative pathology of North American and central African strains of monkeypox virus in a ground squirrel model of the disease","volume":"76","author":"Sbrana","year":"2007","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.virol.2010.03.012_bib23","doi-asserted-by":"crossref","first-page":"539","DOI":"10.3201\/eid1104.040907","article-title":"Experimental infection of prairie dogs with monkeypox virus","volume":"11","author":"Xiao","year":"2005","journal-title":"Emerg. Infect. Dis."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682210001650?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682210001650?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:05:14Z","timestamp":1758585914000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682210001650"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["S0042682210001650"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2010.03.012","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2010,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dosage comparison of Congo Basin and West African strains of monkeypox virus using a prairie dog animal model of systemic orthopoxvirus disease","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2010.03.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}