{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:19:10Z","timestamp":1790857150048,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":716,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100004755","name":"EMD Serono","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004755","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003762","name":"Institut Pasteur","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003762","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2011,8]]},"DOI":"10.1016\/j.virol.2011.05.018","type":"journal-article","created":{"date-parts":[[2011,6,24]],"date-time":"2011-06-24T16:38:21Z","timestamp":1308933501000},"page":"147-153","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Transgenic expression of full-length 2\u2032,5\u2032-oligoadenylate synthetase 1b confers to BALB\/c mice resistance against West Nile virus-induced encephalitis"],"prefix":"10.1016","volume":"417","author":[{"given":"Dominique","family":"Simon-Chazottes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Pascale","family":"Frenkiel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Montagutelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Gu\u00e9net","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Despr\u00e8s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Jacques","family":"Panthier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virol.2011.05.018_bb0005","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1006\/bbrc.1995.1874","article-title":"SARs do not impair position-dependent expression of a kit\/lacZ transgene","volume":"211","author":"De Sepulveda","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.virol.2011.05.018_bb0010","doi-asserted-by":"crossref","first-page":"3024","DOI":"10.2741\/3432","article-title":"The host immunologic response to West Nile encephalitis virus","volume":"14","author":"Diamond","year":"2009","journal-title":"Front. Biosci."},{"key":"10.1016\/j.virol.2011.05.018_bb0015","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1128\/JVI.01305-07","article-title":"Establishment and maintenance of the innate antiviral response to West Nile Virus involves both RIG-I and MDA5 signaling through IPS-1","volume":"82","author":"Fredericksen","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2011.05.018_bb0020","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1006\/viro.1995.1398","article-title":"Interferon-alpha inhibits the murine cytomegalovirus immediate-early gene expression by down-regulating NF-kappa B activity","volume":"211","author":"Gribaudo","year":"1995","journal-title":"Virology"},{"key":"10.1016\/j.virol.2011.05.018_bb0025","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1146\/annurev.med.57.121304.131418","article-title":"West Nile virus: epidemiology and clinical features of an emerging epidemic in the United States","volume":"57","author":"Hayes","year":"2006","journal-title":"Annu. Rev. Med."},{"key":"10.1016\/j.virol.2011.05.018_bb0030","doi-asserted-by":"crossref","first-page":"4624","DOI":"10.1074\/jbc.M508649200","article-title":"The 2\u2032,5\u2032-oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells","volume":"281","author":"Kajaste-Rudnitski","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virol.2011.05.018_bb0035","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0014-5793(00)01338-7","article-title":"A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre-mediated recombination","volume":"470","author":"Kawamoto","year":"2000","journal-title":"FEBS Lett."},{"key":"10.1016\/j.virol.2011.05.018_bb0040","doi-asserted-by":"crossref","first-page":"11898","DOI":"10.1128\/JVI.01003-10","article-title":"Extracellular 2\u2032\u20135\u2032 oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity","volume":"84","author":"Kristiansen","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2011.05.018_bb0045","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1089\/jir.2010.0107","article-title":"The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities","volume":"31","author":"Kristiansen","year":"2011","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.virol.2011.05.018_bb0050","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1002\/jez.10163","article-title":"Expression of the gene of interest fused to the EGFP-expressing gene in transgenic mice derived from selected transgenic embryos","volume":"293","author":"Kubo","year":"2002","journal-title":"J. Exp. Zool."},{"key":"10.1016\/j.virol.2011.05.018_bb0055","doi-asserted-by":"crossref","first-page":"e1000321","DOI":"10.1371\/journal.ppat.1000321","article-title":"Genetic variation in OAS1 is a risk factor for initial infection with West Nile virus in man","volume":"5","author":"Lim","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2011.05.018_bb0060","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.jviromet.2007.05.021","article-title":"Detection of West Nile virus lineages 1 and 2 by real-time PCR","volume":"146","author":"Linke","year":"2007","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.virol.2011.05.018_bb0065","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.virol.2011.05.018_bb0070","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1046\/j.1440-1711.2003.01166.x","article-title":"Infection of mouse neurones by West Nile virus is modulated by the interferon-inducible 2\u2032\u20135\u2032 oligoadenylate synthetase 1b protein","volume":"81","author":"Lucas","year":"2003","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.virol.2011.05.018_bb0075","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3201\/eid0804.010217","article-title":"Introduction of West Nile virus in the Middle East by migrating white storks","volume":"8","author":"Malkinson","year":"2002","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.virol.2011.05.018_bb0080","doi-asserted-by":"crossref","first-page":"11311","DOI":"10.1073\/pnas.172195399","article-title":"A nonsense mutation in the gene encoding 2\u2032\u20135\u2032-oligoadenylate synthetase\/L1 isoform is associated with West Nile virus susceptibility in laboratory mice","volume":"99","author":"Mashimo","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.virol.2011.05.018_bb0085","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0888-7543(03)00176-9","article-title":"Structural and functional genomics and evolutionary relationships in the cluster of genes encoding murine 2\u2032,5\u2032-oligoadenylate synthetases","volume":"82","author":"Mashimo","year":"2003","journal-title":"Genomics"},{"key":"10.1016\/j.virol.2011.05.018_bb0090","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0076-6879(08)02409-9","article-title":"Chapter 9. Studying nonsense-mediated mRNA decay in mammalian cells","volume":"449","author":"Matsuda","year":"2008","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.virol.2011.05.018_bb0095","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0378-1119(91)90434-D","article-title":"Efficient selection for high-expression transfectants with a novel eukaryotic vector","volume":"108","author":"Niwa","year":"1991","journal-title":"Gene"},{"key":"10.1016\/j.virol.2011.05.018_bb0100","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0014-5793(97)00313-X","article-title":"'Green mice' as a source of ubiquitous green cells","volume":"407","author":"Okabe","year":"1997","journal-title":"FEBS Lett."},{"key":"10.1016\/j.virol.2011.05.018_bb0105","doi-asserted-by":"crossref","first-page":"9322","DOI":"10.1073\/pnas.142287799","article-title":"Positional cloning of the murine flavivirus resistance gene","volume":"99","author":"Perelygin","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.virol.2011.05.018_bb0110","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1089\/hum.1997.8.17-2019","article-title":"Promoter attenuation in gene therapy: interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression","volume":"8","author":"Qin","year":"1997","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.virol.2011.05.018_bb0115","doi-asserted-by":"crossref","first-page":"e10537","DOI":"10.1371\/journal.pone.0010537","article-title":"OAS1 polymorphisms are associated with susceptibility to West Nile encephalitis in horses","volume":"5","author":"Rios","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.virol.2011.05.018_bb0135","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.virol.2007.08.017","article-title":"Knock-in of the Oas1b(r) allele into a flavivirus-induced disease susceptible mouse generates the resistant phenotype","volume":"368","author":"Scherbik","year":"2007","journal-title":"Virology"},{"key":"10.1016\/j.virol.2011.05.018_bb0120","doi-asserted-by":"crossref","first-page":"12005","DOI":"10.1128\/JVI.01359-07","article-title":"Differential expression of interferon (IFN) regulatory factors and IFN-stimulated genes at early times after West Nile virus infection of mouse embryo fibroblasts","volume":"81","author":"Scherbik","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2011.05.018_bb0125","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0378-1119(01)00550-9","article-title":"Optimization of transcriptional regulatory elements for constructing plasmid vectors","volume":"272","author":"Xu","year":"2001","journal-title":"Gene"},{"key":"10.1016\/j.virol.2011.05.018_bb0130","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1038\/ng2087","article-title":"On the subspecific origin of the laboratory mouse","volume":"39","author":"Yang","year":"2007","journal-title":"Nat. Genet."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682211002649?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682211002649?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:12:09Z","timestamp":1758586329000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682211002649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["S0042682211002649"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2011.05.018","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2011,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transgenic expression of full-length 2\u2032,5\u2032-oligoadenylate synthetase 1b confers to BALB\/c mice resistance against West Nile virus-induced encephalitis","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2011.05.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}