{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T10:31:38Z","timestamp":1791109898875,"version":"4.1.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":532,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1016\/j.virol.2011.11.021","type":"journal-article","created":{"date-parts":[[2011,12,15]],"date-time":"2011-12-15T22:25:25Z","timestamp":1323987925000},"page":"49-57","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":158,"title":["Emergence and epidemic occurrence of enterovirus 68 respiratory infections in The Netherlands in 2010"],"prefix":"10.1016","volume":"423","author":[{"given":"Adam","family":"Meijer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"van der Sanden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca E.P.","family":"Snijders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Jaramillo-Gutierrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Bont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelis K.","family":"van der Ent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter","family":"Overduin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shireen L.","family":"Jenny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edin","family":"Jusic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harrie G.A.M.","family":"van der Avoort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavin J.D.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e9 A.","family":"Donker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion P.G.","family":"Koopmans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virol.2011.11.021_bb0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-5573-8-1","article-title":"WINPEPI updated: computer programs for epidemiologists, and their teaching potential","volume":"8","author":"Abramson","year":"2011","journal-title":"Epidemiol. Perspect. Innov."},{"key":"10.1016\/j.virol.2011.11.021_bb0010","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1128\/JCM.37.3.524-530.1999","article-title":"Improved detection of rhinoviruses in clinical samples by using a newly developed nested reverse transcription-PCR assay","volume":"37","author":"Andeweg","year":"1999","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.virol.2011.11.021_bb0015","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1051\/medsci\/20092511921","article-title":"Ent\u00e9rovirus non poliomy\u00e9litiques et pathologies respiratoires","volume":"25","author":"Andr\u00e9oletti","year":"2009","journal-title":"Med. Sci. (Paris)"},{"key":"10.1016\/j.virol.2011.11.021_bb0020","doi-asserted-by":"crossref","first-page":"4218","DOI":"10.1128\/JCM.40.11.4218-4223.2002","article-title":"Human rhinovirus 87 and enterovirus 68 represent a unique serotype with rhinovirus and enterovirus features","volume":"40","author":"Blomqvist","year":"2002","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.virol.2011.11.021_bb0025","first-page":"1301","article-title":"Clusters of acute respiratory illness associated with human enterovirus 68 \u2014 Asia, Europe, and United States, 2008\u20132010","volume":"60","author":"Centers for Disease Control and Prevention (CDC)","year":"2011","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.virol.2011.11.021_bb0030","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1128\/AEM.70.3.1717-1722.2004","article-title":"Virucidal efficacy of glutaraldehyde against enteroviruses is related to the location of lysine residues in exposed structures of the VP1 capsid protein","volume":"70","author":"Chambon","year":"2004","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.virol.2011.11.021_bb0035","doi-asserted-by":"crossref","first-page":"996","DOI":"10.3201\/eid1606.100063","article-title":"Rhinovirus C and respiratory exacerbations in children with cystic fibrosis","volume":"16","author":"de Almeida","year":"2010","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.virol.2011.11.021_bb0040","series-title":"Continuous Morbidity Registration at Dutch Sentinel General Practice Network 2009","author":"Donker","year":"2011"},{"key":"10.1016\/j.virol.2011.11.021_bb0055","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1186\/1471-2148-7-214","article-title":"BEAST: Bayesian evolutionary analysis by sampling trees","volume":"7","author":"Drummond","year":"2007","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.virol.2011.11.021_bb0045","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1093\/molbev\/msi103","article-title":"Bayesian coalescent inference of past population dynamics from molecular sequences","volume":"22","author":"Drummond","year":"2005","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.virol.2011.11.021_bb0050","doi-asserted-by":"crossref","first-page":"e88","DOI":"10.1371\/journal.pbio.0040088","article-title":"Relaxed phylogenetics and dating with confidence","volume":"4","author":"Drummond","year":"2006","journal-title":"PLoS Biol."},{"key":"10.1016\/j.virol.2011.11.021_bb0060","doi-asserted-by":"crossref","first-page":"e6572","DOI":"10.1371\/journal.pone.0006572","article-title":"The association between intrauterine inflammation and spontaneous vaginal delivery at term: a cross-sectional study","volume":"4","author":"Houben","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.virol.2011.11.021_bb0065","first-page":"1430","article-title":"Enterovirus 68 among children with severe acute respiratory infection, the Philippines","volume":"17","author":"Imamura","year":"2011","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.virol.2011.11.021_bb0070","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1159\/000065866","article-title":"Human rhinovirus 87 identified as human enterovirus 68 by VP4-based molecular diagnosis","volume":"45","author":"Ishiko","year":"2002","journal-title":"Intervirology"},{"key":"10.1016\/j.virol.2011.11.021_bb0075","first-page":"1494","article-title":"Enterovirus 68 in children with acute respiratory tract infections, Osaka, Japan","volume":"17","author":"Kaida","year":"2011","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.virol.2011.11.021_bb0080","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1128\/jcm.32.2.285-291.1994","article-title":"Nested PCR for specific detection and rapid identification of human picornaviruses","volume":"32","author":"K\u00e4mmerer","year":"1994","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.virol.2011.11.021_bb0085","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/0042-6822(71)90329-1","article-title":"A collaborative report: rhinoviruses \u2014 extension of the numbering system","volume":"43","author":"Kapikian","year":"1971","journal-title":"Virology"},{"key":"10.1016\/j.virol.2011.11.021_bb0090","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1023\/B:EJEP.0000040530.98310.0c","article-title":"The Wheezing Illnesses Study Leidsche Rijn (WHISTLER): rationale and design","volume":"19","author":"Katier","year":"2004","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.virol.2011.11.021_bb0095","first-page":"1","article-title":"Enterovirus surveillance\u2014United States, 1970\u20132005","volume":"55","author":"Khetsuriani","year":"2006","journal-title":"MMWR Surveill. Summ."},{"key":"10.1016\/j.virol.2011.11.021_bb0100","doi-asserted-by":"crossref","first-page":"793","DOI":"10.5858\/2010-0174-CR.1","article-title":"A fatal central nervous system enterovirus 68 infection","volume":"135","author":"Kreuter","year":"2011","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.virol.2011.11.021_bb0105","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0168-1702(94)90096-5","article-title":"Characterization of the N-terminal part of the neutralizing antigenic site I of coxsackievirus B4 by mutation analysis of antigen chimeras","volume":"34","author":"McPhee","year":"1994","journal-title":"Virus Res."},{"key":"10.1016\/j.virol.2011.11.021_bb0110","doi-asserted-by":"crossref","first-page":"2698","DOI":"10.1128\/JCM.00542-06","article-title":"Sensitive, seminested PCR amplification of VP1 sequences for direct identification of all enterovirus serotypes from original clinical specimens","volume":"44","author":"Nix","year":"2006","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.virol.2011.11.021_bb0115","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jcv.2007.09.011","article-title":"Clinical validation of a new real-time PCR assay for detection of enteroviruses and parechoviruses, and implications for diagnostic procedures","volume":"41","author":"Noordhoek","year":"2008","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.virol.2011.11.021_bb0120","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1099\/vir.0.18647-0","article-title":"Sequencing of \u2018untypable\u2019 enteroviruses reveals two new types, EV-77 and EV-78, within human enterovirus type B and substitutions in the BC loop of the VP1 protein for known types","volume":"84","author":"Norder","year":"2003","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2011.11.021_bb0125","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1128\/JVI.73.3.1941-1948.1999","article-title":"Molecular evolution of the human enteroviruses: correlation of serotype with VP1 sequence and application to picornavirus classification","volume":"73","author":"Oberste","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2011.11.021_bb0130","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1099\/vir.0.79925-0","article-title":"Enterovirus 68 is associated with respiratory illness and shares biological features with both the enteroviruses and the rhinoviruses","volume":"85","author":"Oberste","year":"2004","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2011.11.021_bb0135","first-page":"321","article-title":"Proefonderzoek naar de frequentie en de aetiologie van griepachtige ziekten in de winter 1963\u20131964","volume":"8","author":"Pel","year":"1965","journal-title":"Huisarts Wet."},{"key":"10.1016\/j.virol.2011.11.021_bb0140","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.patbio.2010.07.010","article-title":"Molecular diagnosis of respiratory enterovirus infections: use of PCR and molecular identification for a best approach of the main circulating strains during 2008","volume":"59","author":"Petitjean-Lecherbonnier","year":"2011","journal-title":"Pathol. Biol. (Paris)"},{"key":"10.1016\/j.virol.2011.11.021_bb0145","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1128\/JCM.01814-10","article-title":"Phylogenetic patterns of human respiratory picornavirus species, including the newly identified group C rhinoviruses, during one-year surveillance of an hospitalized patient population in Italy","volume":"49","author":"Piralla","year":"2011","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.virol.2011.11.021_bb0155","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.jcv.2011.06.019","article-title":"Upsurge of human enterovirus 68 infections in patients with severe respiratory tract infections","volume":"52","author":"Rahamat-Langendoen","year":"2011","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.virol.2011.11.021_bb0150","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/nature06945","article-title":"The genomic and epidemiological dynamics of human influenza A virus","volume":"453","author":"Rambaut","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.virol.2011.11.021_bb0160","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1086\/524312","article-title":"A recently identified rhinovirus genotype is associated with severe respiratory-tract infection in children in Germany","volume":"196","author":"Renwick","year":"2007","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2011.11.021_bb0165","series-title":"Human Enterovirus Infections","author":"Rotbart","year":"1995"},{"key":"10.1016\/j.virol.2011.11.021_bb0170","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1099\/0022-1317-83-2-333","article-title":"Genetic clustering of all 102 human rhinovirus prototype strains: serotype 87 is close to human enterovirus 70","volume":"83","author":"Savolainen","year":"2002","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2011.11.021_bb0175","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.3390\/v1031178","article-title":"All known human rhinovirus species are present in sputum specimens of military recruits during respiratory infection","volume":"1","author":"Savolainen-Kopra","year":"2009","journal-title":"Viruses"},{"key":"10.1016\/j.virol.2011.11.021_bb0180","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1093\/oxfordjournals.aje.a120693","article-title":"A probable new human picornavirus associated with respiratory diseases","volume":"85","author":"Schieble","year":"1967","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.virol.2011.11.021_bb0185","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.jviromet.2009.12.016","article-title":"Performance of enterovirus genotyping targeting the VP1 and VP2 regions on non-typeable isolates and patient specimens","volume":"165","author":"She","year":"2010","journal-title":"J. Virol. Meth."},{"key":"10.1016\/j.virol.2011.11.021_bb0190","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1002\/jmv.21894","article-title":"Cellular tropism of human enterovirus D species serotypes EV-94, EV-70, and EV-68 in vitro: implications for pathogenesis","volume":"82","author":"Smura","year":"2010","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.virol.2011.11.021_bb0195","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1080\/10635150390238879","article-title":"Hierarchical phylogenetic models for analyzing multipartite sequence data","volume":"52","author":"Suchard","year":"2003","journal-title":"Syst. Biol."},{"key":"10.1016\/j.virol.2011.11.021_bb0200","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1186\/1743-422X-8-288","article-title":"Longitudinal molecular microbial analysis of influenza-like illness in New York City, May 2009 through May 2010","volume":"8","author":"Tokarz","year":"2011","journal-title":"Virol. J."},{"key":"10.1016\/j.virol.2011.11.021_bb0205","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1164\/rccm.200905-0716OC","article-title":"The influence of neonatal lung function on rhinovirus associated wheeze","volume":"183","author":"van der Zalm","year":"2011","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.virol.2011.11.021_bb0210","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1542\/peds.2007-3139","article-title":"Prevalence and impact of respiratory viral infections in young children with cystic fibrosis: prospective cohort study","volume":"122","author":"van Ewijk","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.virol.2011.11.021_bb0215","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1086\/431982","article-title":"A case\u2013control study of acute respiratory tract infection in general practice patients in The Netherlands","volume":"41","author":"van Gageldonk-Lafeber","year":"2005","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.virol.2011.11.021_bb0220","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s00248-010-9636-3","article-title":"Broad spectrum respiratory pathogen analysis of throat swabs from military recruits reveals interference between rhinoviruses and adenoviruses","volume":"59","author":"Wang","year":"2010","journal-title":"Microb. Ecol."},{"key":"10.1016\/j.virol.2011.11.021_bb0225","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1542\/pir.19.6.183","article-title":"Enterovirus infections","volume":"19","author":"Zaoutis","year":"1998","journal-title":"Pediatr. Rev."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682211005502?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682211005502?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:13:46Z","timestamp":1758586426000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682211005502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S0042682211005502"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2011.11.021","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2012,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Emergence and epidemic occurrence of enterovirus 68 respiratory infections in The Netherlands in 2010","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2011.11.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}