{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:37:20Z","timestamp":1792255040757,"version":"4.4.0"},"reference-count":55,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":503,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["1R15CA101873-01"],"award-info":[{"award-number":["1R15CA101873-01"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["1R15CA126855-01"],"award-info":[{"award-number":["1R15CA126855-01"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1016\/j.virol.2011.12.023","type":"journal-article","created":{"date-parts":[[2012,1,30]],"date-time":"2012-01-30T21:19:22Z","timestamp":1327958362000},"page":"53-60","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":97,"title":["Human papillomavirus type 16 E6 and E 7 proteins alter NF-kB in cultured cervical epithelial cells and inhibition of NF-kB promotes cell growth and immortalization"],"prefix":"10.1016","volume":"425","author":[{"given":"Erik R.","family":"Vandermark","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krysta A.","family":"Deluca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney R.","family":"Gardner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel F.","family":"Marker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia N.","family":"Schreiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Strickland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katelynn M.","family":"Wilton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumona","family":"Mondal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig D.","family":"Woodworth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.virol.2011.12.023_bb0005","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/nrd2781","article-title":"Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls","volume":"8","author":"Baud","year":"2009","journal-title":"Nat. Rev. Drug Discov."},{"issue":"8","key":"10.1016\/j.virol.2011.12.023_bb0010","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/dc.20514","article-title":"Upregulation of nuclear factor-kappaB (NF-kappaB) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus or disease outcome in cervical cancer","volume":"34","author":"Branca","year":"2006","journal-title":"Diagn. Cytopathol."},{"issue":"1","key":"10.1016\/j.virol.2011.12.023_bb0015","first-page":"117","article-title":"Site and origin of squamous cervical cancer: a histomorphologic study","volume":"62","author":"Burghardt","year":"1983","journal-title":"Obstet. Gynecol."},{"issue":"9","key":"10.1016\/j.virol.2011.12.023_bb0020","doi-asserted-by":"crossref","first-page":"4174","DOI":"10.1128\/JVI.74.9.4174-4182.2000","article-title":"Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31","volume":"74","author":"Chang","year":"2000","journal-title":"J. Virol."},{"issue":"15","key":"10.1016\/j.virol.2011.12.023_bb0025","doi-asserted-by":"crossref","first-page":"9966","DOI":"10.1073\/pnas.162082999","article-title":"Role of the E1A Rb-binding domain in repression of the NF-kappa B-dependent defense against tumor necrosis factor-alpha","volume":"99","author":"Cook","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"6923","key":"10.1016\/j.virol.2011.12.023_bb0030","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/nature01283","article-title":"NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia","volume":"421","author":"Dajee","year":"2003","journal-title":"Nature"},{"issue":"10","key":"10.1016\/j.virol.2011.12.023_bb0035","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1177\/154405910808701011","article-title":"Host defense peptides in the oral cavity and the lung: similarities and differences","volume":"87","author":"Diamond","year":"2008","journal-title":"J. Dent. Res."},{"issue":"6","key":"10.1016\/j.virol.2011.12.023_bb0040","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.1128\/jvi.63.6.2650-2656.1989","article-title":"A point mutational analysis of human papillomavirus type 16 E7 protein","volume":"63","author":"Edmonds","year":"1989","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.virol.2011.12.023_bb0045","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ccr.2009.12.041","article-title":"Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner","volume":"17","author":"Erez","year":"2010","journal-title":"Cancer Cell"},{"issue":"1","key":"10.1016\/j.virol.2011.12.023_bb0050","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1006\/viro.2000.0363","article-title":"A functional NF-kappaB binding site in the human papillomavirus type 16 long control region","volume":"272","author":"Fontaine","year":"2000","journal-title":"Virology"},{"issue":"42","key":"10.1016\/j.virol.2011.12.023_bb0055","doi-asserted-by":"crossref","first-page":"4930","DOI":"10.1038\/sj.onc.1203860","article-title":"Transcriptional regulation of the major histocompatibility complex (MHC) class I heavy chain, TAP1 and LMP2 genes by the human papillomavirus (HPV) type 6b, 16 and 18 E7 oncoproteins","volume":"19","author":"Georgopoulos","year":"2000","journal-title":"Oncogene"},{"issue":"3","key":"10.1016\/j.virol.2011.12.023_bb0060","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.cell.2004.07.013","article-title":"IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer","volume":"118","author":"Greten","year":"2004","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.virol.2011.12.023_bb0065","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1128\/jvi.65.1.473-478.1991","article-title":"The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells","volume":"65","author":"Halbert","year":"1991","journal-title":"J. Virol."},{"issue":"5","key":"10.1016\/j.virol.2011.12.023_bb0070","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.4049\/jimmunol.178.5.3186","article-title":"TLR9 expression and function is abolished by the cervical cancer-associated human papillomavirus type 16","volume":"178","author":"Hasan","year":"2007","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.virol.2011.12.023_bb0075","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1006\/viro.2002.1468","article-title":"Differential production of cytokines and activation of NF-kappaB in HPV-transformed keratinocytes","volume":"298","author":"Havard","year":"2002","journal-title":"Virology"},{"issue":"2","key":"10.1016\/j.virol.2011.12.023_bb0080","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.virol.2004.10.030","article-title":"High levels of p105 (NFKB1) and p100 (NFKB2) proteins in HPV16-transformed keratinocytes: role of E6 and E7 oncoproteins","volume":"331","author":"Havard","year":"2005","journal-title":"Virology"},{"issue":"51","key":"10.1016\/j.virol.2011.12.023_bb0085","doi-asserted-by":"crossref","first-page":"6758","DOI":"10.1038\/sj.onc.1209943","article-title":"NF-kappaB and the immune response","volume":"25","author":"Hayden","year":"2006","journal-title":"Oncogene"},{"issue":"13","key":"10.1016\/j.virol.2011.12.023_bb0090","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1038\/sj.onc.1206198","article-title":"Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin","volume":"22","author":"Hinata","year":"2003","journal-title":"Oncogene"},{"issue":"51","key":"10.1016\/j.virol.2011.12.023_bb0095","doi-asserted-by":"crossref","first-page":"6844","DOI":"10.1038\/sj.onc.1209941","article-title":"Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses","volume":"25","author":"Hiscott","year":"2006","journal-title":"Oncogene"},{"issue":"17","key":"10.1016\/j.virol.2011.12.023_bb0100","doi-asserted-by":"crossref","first-page":"8710","DOI":"10.1128\/JVI.76.17.8710-8721.2002","article-title":"Down regulation of the interleukin-8 promoter by human papillomavirus type 16 E6 and E7 through effects on CREB binding protein\/p300 and P\/CAF","volume":"76","author":"Huang","year":"2002","journal-title":"J. Virol."},{"issue":"17","key":"10.1016\/j.virol.2011.12.023_bb0105","doi-asserted-by":"crossref","first-page":"9013","DOI":"10.1128\/JVI.00002-11","article-title":"NF-{kappa}B protects HPV38E6\/E7-immortalized human keratinocyte against TNF-{alpha} and UV-mediated apoptosis","volume":"85","author":"Hussain","year":"2011","journal-title":"J. Virol."},{"issue":"11","key":"10.1016\/j.virol.2011.12.023_bb0110","doi-asserted-by":"crossref","first-page":"5301","DOI":"10.1128\/JVI.01942-05","article-title":"Human papillomavirus type 16 E6 activates NF-kappaB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner","volume":"80","author":"James","year":"2006","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virol.2011.12.023_bb0115","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1006\/viro.1997.8851","article-title":"Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis","volume":"239","author":"Jones","year":"1997","journal-title":"Virology"},{"issue":"7092","key":"10.1016\/j.virol.2011.12.023_bb0120","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/nature04870","article-title":"Nuclear factor-kappaB in cancer development and progression","volume":"441","author":"Karin","year":"2006","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.virol.2011.12.023_bb0125","doi-asserted-by":"crossref","first-page":"a000141","DOI":"10.1101\/cshperspect.a000141","article-title":"NF-kappaB as a critical link between inflammation and cancer","volume":"1","author":"Karin","year":"2009","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"1","key":"10.1016\/j.virol.2011.12.023_bb0130","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1006\/excr.1997.3729","article-title":"Glucocorticoids stimulate growth of human papillomavirus type 16 (HPV16)-immortalized human keratinocytes and support HPV16-mediated immortalization without affecting the levels of HPV16 E6\/E7 mRNA","volume":"236","author":"Khan","year":"1997","journal-title":"Exp. Cell Res."},{"issue":"6569","key":"10.1016\/j.virol.2011.12.023_bb0135","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/380079a0","article-title":"Telomerase activation by the E6 gene product of human papillomavirus type 16","volume":"380","author":"Klingelhutz","year":"1996","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.virol.2011.12.023_bb0140","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.it.2005.04.003","article-title":"Inflammation-associated cancer: NF-kappaB is the lynchpin","volume":"26","author":"Li","year":"2005","journal-title":"Trends Immunol."},{"issue":"7","key":"10.1016\/j.virol.2011.12.023_bb0145","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.cell.2005.04.014","article-title":"IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis","volume":"121","author":"Maeda","year":"2005","journal-title":"Cell"},{"issue":"10","key":"10.1016\/j.virol.2011.12.023_bb0150","doi-asserted-by":"crossref","first-page":"4417","DOI":"10.1128\/jvi.63.10.4417-4421.1989","article-title":"The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes","volume":"63","author":"Munger","year":"1989","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virol.2011.12.023_bb0155","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/sj.onc.1206043","article-title":"NF-kappaB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix","volume":"22","author":"Nair","year":"2003","journal-title":"Oncogene"},{"issue":"9","key":"10.1016\/j.virol.2011.12.023_bb0160","doi-asserted-by":"crossref","first-page":"4283","DOI":"10.1128\/JVI.75.9.4283-4296.2001","article-title":"Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappaB-responsive genes in cervical keratinocytes","volume":"75","author":"Nees","year":"2001","journal-title":"J. Virol."},{"issue":"6","key":"10.1016\/j.virol.2011.12.023_bb0165","first-page":"661","article-title":"Human papillomavirus type 16 E7 impairs the activation of the interferon regulatory factor-1","volume":"5","author":"Perea","year":"2000","journal-title":"Int. J. Mol. Med."},{"issue":"9","key":"10.1016\/j.virol.2011.12.023_bb0170","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","article-title":"A new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"Pfaffl","year":"2001","journal-title":"Nucleic Acids Res."},{"issue":"7007","key":"10.1016\/j.virol.2011.12.023_bb0175","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/nature02924","article-title":"NF-kappaB functions as a tumour promoter in inflammation-associated cancer","volume":"431","author":"Pikarsky","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.virol.2011.12.023_bb0180","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.2741\/1635","article-title":"Constitutive activation of nuclear factor -kB: preferntial homodimerization of p50 subunits in cervical carcinoma","volume":"10","author":"Prusty","year":"2005","journal-title":"Front. Biosci."},{"issue":"13","key":"10.1016\/j.virol.2011.12.023_bb0185","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1101\/gad.12.13.2061","article-title":"Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity","volume":"12","author":"Ronco","year":"1998","journal-title":"Genes Dev."},{"issue":"20","key":"10.1016\/j.virol.2011.12.023_bb0190","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1038\/onc.2010.611","article-title":"Activation of nuclear factor-kappa B signalling promotes cellular senescence","volume":"30","author":"Rovillain","year":"2011","journal-title":"Oncogene"},{"issue":"6","key":"10.1016\/j.virol.2011.12.023_bb0195","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/0092-8674(90)90409-8","article-title":"The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53","volume":"63","author":"Scheffner","year":"1990","journal-title":"Cell"},{"issue":"5","key":"10.1016\/j.virol.2011.12.023_bb0200","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1073\/pnas.95.5.2307","article-title":"Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB","volume":"95","author":"Seitz","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"28","key":"10.1016\/j.virol.2011.12.023_bb0205","doi-asserted-by":"crossref","first-page":"25576","DOI":"10.1074\/jbc.M201884200","article-title":"The human papillomavirus oncoprotein E7 attenuates NF-kappa B activation by targeting the Ikappa B kinase complex","volume":"277","author":"Spitkovsky","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"17","key":"10.1016\/j.virol.2011.12.023_bb0210","doi-asserted-by":"crossref","first-page":"14897","DOI":"10.1074\/jbc.M210849200","article-title":"NF-kappa B-dependent induction of cyclin D1 by retinoblastoma protein (pRB) family proteins and tumor-derived pRB mutants","volume":"278","author":"Takebayashi","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"5288","key":"10.1016\/j.virol.2011.12.023_bb0215","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1126\/science.274.5288.787","article-title":"Suppression of TNF-alpha-induced apoptosis by NF-kappaB","volume":"274","author":"Van Antwerp","year":"1996","journal-title":"Science"},{"issue":"14","key":"10.1016\/j.virol.2011.12.023_bb0220","first-page":"3299","article-title":"Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel\/nuclear factor-kappaB signaling","volume":"59","author":"van Hogerlinden","year":"1999","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.virol.2011.12.023_bb0225","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/mc.20116","article-title":"Biological and chemical inhibitors of NF-kappaB sensitize SiHa cells to cisplatin-induced apoptosis","volume":"44","author":"Venkatraman","year":"2005","journal-title":"Mol. Carcinog."},{"issue":"5","key":"10.1016\/j.virol.2011.12.023_bb0230","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1002\/ijc.2910510527","article-title":"Inhibition of tumorigenicity of cervical cancer cells in nude mice by HPV E6-E7 anti-sense RNA","volume":"51","author":"von Knebel Doeberitz","year":"1992","journal-title":"Int. J. Cancer"},{"issue":"5","key":"10.1016\/j.virol.2011.12.023_bb0235","doi-asserted-by":"crossref","first-page":"3485","DOI":"10.1128\/MCB.19.5.3485","article-title":"Transcriptional cross talk between NF-kappaB and p53","volume":"19","author":"Webster","year":"1999","journal-title":"Mol. Cell. Biol."},{"issue":"5","key":"10.1016\/j.virol.2011.12.023_bb0260","first-page":"1544","article-title":"Comparative lymphokine secretion by cultured normal human cervical keratinocytes, papillomavirus-immortalized, and carcinoma cell lines","volume":"142","author":"Woodworth","year":"1993","journal-title":"Am. J. Pathol."},{"issue":"8","key":"10.1016\/j.virol.2011.12.023_bb0240","first-page":"4018","article-title":"Transformation of rat hepatocytes by transfection with simian virus 40 DNA to yield proliferating differentiated cells","volume":"46","author":"Woodworth","year":"1986","journal-title":"Cancer Res."},{"issue":"16","key":"10.1016\/j.virol.2011.12.023_bb0245","first-page":"4620","article-title":"Characterization of normal human exocervical epithelial cells immortalized in vitro by papillomavirus types 16 and 18 DNA","volume":"48","author":"Woodworth","year":"1988","journal-title":"Cancer Res."},{"issue":"12","key":"10.1016\/j.virol.2011.12.023_bb0265","first-page":"3709","article-title":"Human cervical and foreskin epithelial cells immortalized by human papillomavirus DNAs exhibit dysplastic differentiation in vivo","volume":"50","author":"Woodworth","year":"1990","journal-title":"Cancer Res."},{"issue":"4","key":"10.1016\/j.virol.2011.12.023_bb0250","first-page":"619","article-title":"Recombinant retroviruses encoding human papillomavirus type 18 E6 and E7 genes stimulate proliferation and delay differentiation of human keratinocytes early after infection","volume":"7","author":"Woodworth","year":"1992","journal-title":"Oncogene"},{"issue":"7","key":"10.1016\/j.virol.2011.12.023_bb0255","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1073\/pnas.92.7.2840","article-title":"Interleukin 1 alpha and tumor necrosis factor alpha stimulate autocrine amphiregulin expression and proliferation of human papillomavirus-immortalized and carcinoma-derived cervical epithelial cells","volume":"92","author":"Woodworth","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"21","key":"10.1016\/j.virol.2011.12.023_bb0270","doi-asserted-by":"crossref","first-page":"11461","DOI":"10.1128\/JVI.00538-10","article-title":"NFX1 plays a role in human papillomavirus type 16 E6 activation of NFkappaB activity","volume":"84","author":"Xu","year":"2010","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virol.2011.12.023_bb0275","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1101\/gad.1160904","article-title":"NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK","volume":"18","author":"Zhang","year":"2004","journal-title":"Genes Dev."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682212000165?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682212000165?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:14:11Z","timestamp":1758586451000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682212000165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":55,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S0042682212000165"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2011.12.023","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Human papillomavirus type 16 E6 and E 7 proteins alter NF-kB in cultured cervical epithelial cells and inhibition of NF-kB promotes cell growth and immortalization","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2011.12.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}