{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T17:55:37Z","timestamp":1791482137099,"version":"4.3.4"},"reference-count":27,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,2,5]],"date-time":"2014-02-05T00:00:00Z","timestamp":1391558400000},"content-version":"vor","delay-in-days":369,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"NIH\/NIAID","award":["U01AI075419"],"award-info":[{"award-number":["U01AI075419"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.virol.2012.09.041","type":"journal-article","created":{"date-parts":[[2012,10,24]],"date-time":"2012-10-24T09:46:38Z","timestamp":1351071998000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":137,"title":["P-body components LSM1, GW182, DDX3, DDX6 and XRN1 are recruited to WNV replication sites and positively regulate viral replication"],"prefix":"10.1016","volume":"436","author":[{"given":"Harendra S.","family":"Chahar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuiping","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Manjunath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virol.2012.09.041_bib1","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1099\/vir.0.015909-0","article-title":"Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein","volume":"91","author":"Angus","year":"2010","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2012.09.041_bib2","doi-asserted-by":"crossref","first-page":"13922","DOI":"10.1128\/JVI.01517-07","article-title":"DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication","volume":"81","author":"Ariumi","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2012.09.041_bib3","doi-asserted-by":"crossref","first-page":"6882","DOI":"10.1128\/JVI.02418-10","article-title":"Hepatitis C virus hijacks P-body and stress granule components around lipid droplets","volume":"85","author":"Ariumi","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2012.09.041_bib4","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.cell.2005.07.031","article-title":"Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation","volume":"122","author":"Bagga","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.virol.2012.09.041_bib5","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.chom.2008.03.004","article-title":"P-bodies, stress granules, and viral life cycles","volume":"3","author":"Beckham","year":"2008","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.virol.2012.09.041_bib6","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1101\/gad.1424106","article-title":"mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1a:DCP2 decapping complexes","volume":"20","author":"Behm-Ansmant","year":"2006","journal-title":"Genes Dev."},{"key":"10.1016\/j.virol.2012.09.041_bib7","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1146\/annurev.micro.56.012302.160654","article-title":"The molecular biology of West Nile Virus: a new invader of the western hemisphere","volume":"56","author":"Brinton","year":"2002","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.virol.2012.09.041_bib8","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1742-4690-6-26","article-title":"Suppression of HIV-1 replication by microRNA effectors","volume":"6","author":"Chable-Bessia","year":"2009","journal-title":"Retrovirology"},{"key":"10.1016\/j.virol.2012.09.041_bib9","doi-asserted-by":"crossref","first-page":"e27551","DOI":"10.1371\/journal.pone.0027551","article-title":"Ago-2-mediated slicer activity is essential for anti-flaviviral efficacy of RNAi","volume":"6","author":"Chen","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.virol.2012.09.041_bib10","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1128\/JVI.01657-10","article-title":"Poliovirus-mediated disruption of cytoplasmic processing bodies","volume":"85","author":"Dougherty","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2012.09.041_bib11","doi-asserted-by":"crossref","first-page":"9041","DOI":"10.1073\/pnas.0703348104","article-title":"Interaction of TIA-1\/TIAR with West Nile and dengue virus products in infected cells interferes with stress granule formation and processing body assembly","volume":"104","author":"Emara","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.virol.2012.09.041_bib12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nrm2080","article-title":"P-bodies: at the crossroads of post-transcriptional pathways","volume":"8","author":"Eulalio","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.virol.2012.09.041_bib13","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1091\/mbc.01-11-0544","article-title":"A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles","volume":"13","author":"Eystathioy","year":"2002","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.virol.2012.09.041_bib14","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1261\/rna.5810203","article-title":"The GW182 protein colocalizes with mRNA degradation associated proteins hDCP1a and hLSm4 in cytoplasmic GW bodies","volume":"9","author":"Eystathioy","year":"2003","journal-title":"RNA"},{"key":"10.1016\/j.virol.2012.09.041_bib15","doi-asserted-by":"crossref","first-page":"3015","DOI":"10.2174\/092986711796391688","article-title":"Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication","volume":"18","author":"Garbelli","year":"2011","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.virol.2012.09.041_bib16","doi-asserted-by":"crossref","first-page":"10438","DOI":"10.1128\/JVI.00986-10","article-title":"The endoplasmic reticulum provides the membrane platform for biogenesis of the flavivirus replication complex","volume":"84","author":"Gillespie","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2012.09.041_bib17","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1126\/science.1122689","article-title":"Zebrafish miR-430 promotes deadenylation and clearance of maternal mRNAs","volume":"312","author":"Giraldez","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.virol.2012.09.041_bib18","doi-asserted-by":"crossref","first-page":"6810","DOI":"10.1128\/JVI.00397-10","article-title":"DDX6 (Rck\/p54) is required for efficient hepatitis C virus replication but not for internal ribosome entry site-directed translation","volume":"84","author":"Jangra","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2012.09.041_bib19","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0065-3527(03)59002-9","article-title":"Molecular biology of flaviviruses","volume":"59","author":"Lindenbach","year":"2003","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.virol.2012.09.041_bib20","doi-asserted-by":"crossref","first-page":"S98","DOI":"10.1038\/nm1144","article-title":"Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses","volume":"10","author":"Mackenzie","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.virol.2012.09.041_bib21","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.molcel.2009.06.003","article-title":"Cellular microRNA and P-bodies modulate host\u2013HIV-1 interactions","volume":"34","author":"Nathans","year":"2009","journal-title":"Mol. Cell"},{"key":"10.1016\/j.virol.2012.09.041_bib22","doi-asserted-by":"crossref","first-page":"8740","DOI":"10.1128\/JVI.07167-11","article-title":"Hepatitis C virus infection alters P-body composition but is independent of P-body granules","volume":"86","author":"P\u00e9rezVilar\u00f3","year":"2012","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2012.09.041_bib23","doi-asserted-by":"crossref","first-page":"319","DOI":"10.3201\/eid0604.000401","article-title":"Migratory birds and spread of West Nile virus in the Western Hemisphere","volume":"6","author":"Rappole","year":"2000","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.virol.2012.09.041_bib24","doi-asserted-by":"crossref","first-page":"13517","DOI":"10.1073\/pnas.0906413106","article-title":"Translation and replication of Hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates","volume":"106","author":"Scheller","year":"2009","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.virol.2012.09.041_bib25","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.4161\/rna.8.6.17836","article-title":"Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3\u2032 UTR structures","volume":"8","author":"Ward","year":"2011","journal-title":"RNA Biol."},{"key":"10.1016\/j.virol.2012.09.041_bib26","doi-asserted-by":"crossref","first-page":"4034","DOI":"10.1073\/pnas.0510928103","article-title":"MicroRNAs direct rapid deadenylation of mRNA","volume":"103","author":"Wu","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.virol.2012.09.041_bib27","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.cell.2004.09.029","article-title":"Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function","volume":"119","author":"Yedavalli","year":"2004","journal-title":"Cell"}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004268221200493X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004268221200493X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:16:52Z","timestamp":1758586612000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004268221200493X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S004268221200493X"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2012.09.041","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"P-body components LSM1, GW182, DDX3, DDX6 and XRN1 are recruited to WNV replication sites and positively regulate viral replication","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2012.09.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}