{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:51:38Z","timestamp":1791193898959,"version":"4.1.0"},"reference-count":77,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,9,25]],"date-time":"2015-09-25T00:00:00Z","timestamp":1443139200000},"content-version":"vor","delay-in-days":632,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Jiangsu Higher Education Institutions"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.virol.2013.11.008","type":"journal-article","created":{"date-parts":[[2013,11,25]],"date-time":"2013-11-25T23:30:50Z","timestamp":1385422250000},"page":"70-81","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":86,"special_numbering":"C","title":["Cellular DDX3 regulates Japanese encephalitis virus replication by interacting with viral un-translated regions"],"prefix":"10.1016","volume":"449","author":[{"given":"Chen","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling-ling","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng-peng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan-juan","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-xia","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-qiang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-chun","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Ishag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virol.2013.11.008_bib1","doi-asserted-by":"crossref","first-page":"39926","DOI":"10.1074\/jbc.M104248200","article-title":"De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase","volume":"276","author":"Ackermann","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virol.2013.11.008_bib2","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1099\/vir.0.015909-0","article-title":"Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein","volume":"91","author":"Angus","year":"2010","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib3","doi-asserted-by":"crossref","first-page":"13922","DOI":"10.1128\/JVI.01517-07","article-title":"DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication","volume":"81","author":"Ariumi","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib4","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkt543","article-title":"Hepatitis C virus 3\u2032UTR regulates viral translation through direct interactions with the host translation machinery","author":"Bai","year":"2013","journal-title":"Nucleic Acids. Res."},{"key":"10.1016\/j.virol.2013.11.008_bib5","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1091\/mbc.e07-09-0954","article-title":"The DEAD-box RNA helicase Ded1p affects and accumulates in Saccharomyces cerevisiae P-bodies","volume":"19","author":"Beckham","year":"2008","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.virol.2013.11.008_bib6","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.1128\/JVI.77.5.3181-3190.2003","article-title":"Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture","volume":"77","author":"Blight","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib7","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/0042-6822(88)90468-0","article-title":"Sequence and secondary structure analysis of the 5\u2032-terminal region of flavivirus genome RNA","volume":"162","author":"Brinton","year":"1988","journal-title":"Virology"},{"key":"10.1016\/j.virol.2013.11.008_bib8","doi-asserted-by":"crossref","first-page":"6579","DOI":"10.1158\/0008-5472.CAN-05-2415","article-title":"DDX3, a DEAD box RNA helicase with tumor growth\u2013suppressive property and transcriptional regulation activity of the p21waf1\/cip1 promoter, is a candidate tumor suppressor","volume":"66","author":"Chao","year":"2006","journal-title":"Cancer Res."},{"key":"10.1016\/j.virol.2013.11.008_bib9","doi-asserted-by":"crossref","first-page":"3466","DOI":"10.1128\/jvi.71.5.3466-3473.1997","article-title":"RNA-protein interactions: involvement of NS3, NS5, and 3\u2032noncoding regions of Japanese encephalitis virus genomic RNA","volume":"71","author":"Chen","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib10","doi-asserted-by":"crossref","first-page":"4698","DOI":"10.1128\/JVI.01950-10","article-title":"FUSE binding protein 1 interacts with untranslated regions of Japanese encephalitis virus RNA and negatively regulates viral replication","volume":"85","author":"Chien","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib11","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.virol.2008.06.017","article-title":"Bovine lactoferrin inhibits Japanese encephalitis virus by binding to heparan sulfate and receptor for low density lipoprotein","volume":"379","author":"Chien","year":"2008","journal-title":"Virology"},{"key":"10.1016\/j.virol.2013.11.008_bib12","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1002\/jcb.23428","article-title":"The DEAD-box RNA helicase DDX3 interacts with DDX5, co-localizes with it in the cytoplasm during the G2\/M phase of the cycle, and affects its shuttling during mRNP export","volume":"113","author":"Choi","year":"2012","journal-title":"J. Cell Biochem."},{"key":"10.1016\/j.virol.2013.11.008_bib13","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.gene.2005.10.019","article-title":"The DEAD-box protein family of RNA helicases","volume":"367","author":"Cordin","year":"2006","journal-title":"Gene"},{"key":"10.1016\/j.virol.2013.11.008_bib14","doi-asserted-by":"crossref","first-page":"4599","DOI":"10.1128\/JVI.79.8.4599-4609.2005","article-title":"Inhibition of flavivirus infections by antisense oligomers specifically suppressing viral translation and RNA replication","volume":"79","author":"Deas","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib15","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/j.1348-0421.1993.tb03206.x","article-title":"Localization and functions of Japanese encephalitis virus nonstructural proteins NS3 and NS5 for viral RNA synthesis in the infected cells","volume":"37","author":"Edward","year":"1993","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.virol.2013.11.008_bib16","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.1093\/emboj\/21.11.2757","article-title":"An RNA cap (nucleoside-2\u2032-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization","volume":"21","author":"Egloff","year":"2002","journal-title":"EMBO J."},{"key":"10.1016\/j.virol.2013.11.008_bib17","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1186\/1743-422X-8-492","article-title":"Small noncoding RNA modulates Japanese encephalitis virus replication and translation in trans","volume":"8","author":"Fan","year":"2011","journal-title":"Virol J."},{"key":"10.1016\/j.virol.2013.11.008_bib18","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.virol.2005.03.017","article-title":"The RNA helicase DDX1 is involved in restricted HIV-1 Rev function in human astrocytes","volume":"336","author":"Fang","year":"2005","journal-title":"Virology"},{"key":"10.1016\/j.virol.2013.11.008_bib19","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.virol.2004.09.039","article-title":"A DEAD box protein facilitates HIV-1 replication as a cellular co-factor of Rev","volume":"330","author":"Fang","year":"2004","journal-title":"Virology"},{"key":"10.1016\/j.virol.2013.11.008_bib20","doi-asserted-by":"crossref","first-page":"3015","DOI":"10.2174\/092986711796391688","article-title":"Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication","volume":"18","author":"Garbelli","year":"2011","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.virol.2013.11.008_bib21","doi-asserted-by":"crossref","first-page":"4998","DOI":"10.1093\/nar\/gks070","article-title":"The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes","volume":"40","author":"Geissler","year":"2012","journal-title":"Nucleic. Acids. Res."},{"key":"10.1016\/j.virol.2013.11.008_bib22","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0166-0934(00)00270-6","article-title":"Expression and purification of enzymatically active recombinant RNA-dependent RNA polymerase (NS5) of the flavivirus Kunjin","volume":"92","author":"Guyatt","year":"2001","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.virol.2013.11.008_bib23","first-page":"47","article-title":"Tobramycin affinity tag purification of spliceosomes","volume":"257","author":"Hartmuth","year":"2004","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.virol.2013.11.008_bib24","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.virusres.2012.10.032","article-title":"Inhibition of Japanese encephalitis virus infection in vitro and in vivo by pokeweed antiviral protein","volume":"171","author":"Ishag","year":"2013","journal-title":"Virus Res."},{"key":"10.1016\/j.virol.2013.11.008_bib25","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s00705-012-1489-2","article-title":"Griffithsin inhibits Japanese encephalitis virus infection in vitro and in vivo","volume":"158","author":"Ishag","year":"2013","journal-title":"Arch. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib26","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.virusres.2012.05.003","article-title":"Core protein-mediated 5\u2032-3\u2032 annealing of the West Nile virus genomic RNA in vitro","volume":"167","author":"Ivanyi-Nagy","year":"2012","journal-title":"Virus Res."},{"key":"10.1016\/j.virol.2013.11.008_bib27","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.jmb.2008.09.048","article-title":"Poxvirus K7 protein adopts a Bcl-2 fold: biochemical mapping of its interactions with human DEAD box RNA helicase DDX3","volume":"385","author":"Kalverda","year":"2009","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.virol.2013.11.008_bib28","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S1016-8478(23)17085-3","article-title":"Gene structure of the human DDX3 and chromosome mapping of its related sequences","volume":"12","author":"Kim","year":"2001","journal-title":"Mol. Cells"},{"key":"10.1016\/j.virol.2013.11.008_bib29","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1099\/0022-1317-74-4-733","article-title":"Computer-assisted identification of a putative methyltransferase domain in NS5 protein of flaviviruses and lambda 2 protein of reovirus","volume":"74","author":"Koonin","year":"1993","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib30","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1099\/0022-1317-77-9-2077","article-title":"Characterizationof the NTPase activity of japanese encephalitis virus NS3 protein","volume":"77","author":"Kuo","year":"1996","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib31","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1038\/nrd1853","article-title":"Viral and cellular RNA helicases as antiviral targets","volume":"4","author":"Kwong","year":"2005","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.virol.2013.11.008_bib32","doi-asserted-by":"crossref","first-page":"3847","DOI":"10.1091\/mbc.e07-12-1264","article-title":"The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control","volume":"19","author":"Lai","year":"2008","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.virol.2013.11.008_bib34","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.antiviral.2011.01.002","article-title":"Rana catesbeiana ribonuclease inhibits Japanese encephalitis virus (JEV) replication and enhances apoptosis of JEV-infected BHK-21 cells","volume":"89","author":"Lee","year":"2011","journal-title":"Antiviral Res."},{"key":"10.1016\/j.virol.2013.11.008_bib35","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.antiviral.2013.09.002","article-title":"The DEAD-box RNA helicase DDX5 acts as a positive regulator of Japanese encephalitis virus replication by binding to viral 3\u2032 UTR","volume":"100","author":"Li","year":"2013","journal-title":"Antiviral Res."},{"key":"10.1016\/j.virol.2013.11.008_bib36","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.antiviral.2012.03.002","article-title":"Inhibition of Japanese encephalitis virus entry into the cells by the envelope glycoprotein domain III (EDIII) and the loop3 peptide derived from EDIII","volume":"94","author":"Li","year":"2012","journal-title":"Antiviral Res."},{"key":"10.1016\/j.virol.2013.11.008_bib37","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1126\/science.1114016","article-title":"Complete replication of hepatitis C virus in cell culture","volume":"309","author":"Lindenbach","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.virol.2013.11.008_bib38","first-page":"991","article-title":"Flaviviridae: the viruses and their replication","volume":"1","author":"Lindenbach","year":"2001","journal-title":"Fields Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib39","doi-asserted-by":"crossref","first-page":"9608","DOI":"10.1128\/jvi.71.12.9608-9617.1997","article-title":"Trans-complementation of yellow fever virus NS1 reveals a role in early RNA replication","volume":"71","author":"Lindenbach","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib40","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0065-3527(03)59002-9","article-title":"Molecular biology of flaviviruses","volume":"59","author":"Lindenbach","year":"2003","journal-title":"Adv. Virus. Res."},{"key":"10.1016\/j.virol.2013.11.008_bib41","doi-asserted-by":"crossref","first-page":"10004","DOI":"10.1128\/JVI.77.18.10004-10014.2003","article-title":"Functional analysis of mosquito-borne flavivirus conserved sequence elements within 3\u2032 untranslated region of West Nile virus by use of a reporting replicon that differentiates between viral translation and RNA replication","volume":"77","author":"Lo","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib42","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1006\/viro.1998.9156","article-title":"Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A","volume":"245","author":"Mackenzie","year":"1998","journal-title":"Virology"},{"key":"10.1016\/j.virol.2013.11.008_bib43","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1002\/cmdc.201100166","article-title":"Toward the discovery of novel anti-HIV drugs. Second-generation inhibitors of the cellular ATPase DDX3 with improved anti-HIV activity: synthesis, structure-activity relationship analysis, cytotoxicity studies, and target validation","volume":"6","author":"Maga","year":"2011","journal-title":"ChemMedChem"},{"key":"10.1016\/j.virol.2013.11.008_bib44","doi-asserted-by":"crossref","first-page":"15751","DOI":"10.1074\/jbc.274.22.15751","article-title":"Hepatitis C virus core protein binds to a DEAD box RNA helicase","volume":"274","author":"Mamiya","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virol.2013.11.008_bib45","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1099\/vir.0.18883-0","article-title":"Interference in Japanese encephalitis virus infection of Vero cells by a cationic amphiphilic drug, chlorpromazine","volume":"84","author":"Nawa","year":"2003","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib46","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1006\/viro.1999.9659","article-title":"Hepatitis C virus core protein interacts with a human DEAD box protein DDX3","volume":"257","author":"Owsianka","year":"1999","journal-title":"Virology"},{"key":"10.1016\/j.virol.2013.11.008_bib47","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1159\/000015022","article-title":"Assignment of a human putative RNA helicase gene, DDX3, to human X chromosome bands p11. 3\u2192p11. 23","volume":"81","author":"Park","year":"1998","journal-title":"Cytogenet. Cell Genet."},{"key":"10.1016\/j.virol.2013.11.008_bib48","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1016\/j.bmcl.2011.12.135","article-title":"Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors","volume":"22","author":"Radi","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.virol.2013.11.008_bib49","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2174\/157489106775244055","article-title":"Recent advances in flavivirus antiviral drug discovery and vaccine development","volume":"1","author":"Ray","year":"2006","journal-title":"Recent Pat. Antiinfect. Drug Discov."},{"key":"10.1016\/j.virol.2013.11.008_bib50","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/nrm1335","article-title":"DEAD-box proteins: the driving forces behind RNA metabolism","volume":"5","author":"Rocak","year":"2004","journal-title":"Nat. Rev. Mol. Cell Bio."},{"key":"10.1016\/j.virol.2013.11.008_bib51","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.bcp.2009.08.032","article-title":"Human DEAD-box protein 3 has multiple functions in gene regulation and cell cycle control and is a prime target for viral manipulation","volume":"79","author":"Schr\u00f6der","year":"2010","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.virol.2013.11.008_bib52","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/sj.onc.1210687","article-title":"Candidate tumor suppressor DDX3 RNA helicase specifically represses cap-dependent translation by acting as an eIF4E inhibitory protein","volume":"27","author":"Shih","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.virol.2013.11.008_bib53","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1080\/13550280390194037","article-title":"Recent advances in Japanese encephalitis","volume":"9","author":"Solomon","year":"2003","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.virol.2013.11.008_bib54","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1261\/rna.993608","article-title":"A complex RNA motif defined by three discontinuous 5-nucleotide-long strands is essential for Flavivirus RNA replication","volume":"14","author":"Song","year":"2008","journal-title":"RNA."},{"key":"10.1016\/j.virol.2013.11.008_bib55","doi-asserted-by":"crossref","first-page":"3745","DOI":"10.1038\/emboj.2012.220","article-title":"DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs","volume":"31","author":"Soto-Rifo","year":"2012","journal-title":"EMBO J."},{"key":"10.1016\/j.virol.2013.11.008_bib56","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1038\/emboj.2008.126","article-title":"The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response","volume":"27","author":"Soulat","year":"2008","journal-title":"EMBO J."},{"key":"10.1016\/j.virol.2013.11.008_bib57","doi-asserted-by":"crossref","first-page":"e53276","DOI":"10.1371\/journal.pone.0053276","article-title":"Analysis of virion-incorporated host proteins required for Herpes simplex virus type 1 Infection through a RNA interference screen","volume":"8","author":"Stegen","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.virol.2013.11.008_bib58","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1128\/mr.58.3.491-562.1994","article-title":"The alphaviruses: gene expression, replication, and evolution","volume":"58","author":"Strauss","year":"1994","journal-title":"Microbiol. Rev."},{"key":"10.1016\/j.virol.2013.11.008_bib59","doi-asserted-by":"crossref","first-page":"e12826","DOI":"10.1371\/journal.pone.0012826","article-title":"Hepatitis C virus core-derived peptides inhibit genotype 1b viral genome replication via interaction with DDX3X","volume":"5","author":"Sun","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.virol.2013.11.008_bib60","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.1016\/S0264-410X(00)00111-0","article-title":"Adverse events after Japanese encephalitis vaccination: review of post-marketing surveillance data from Japan and the United States","volume":"18","author":"Takahashi","year":"2000","journal-title":"Vaccine"},{"key":"10.1016\/j.virol.2013.11.008_bib61","doi-asserted-by":"crossref","unstructured":"Tsai, T.F., 2000. New initiatives for the control of Japanese encephalitis by vaccination: Minutes of a WHO\/CVI meeting, Bangkok, Thailand, 13\u201315 October 1998. Vaccine 18, pp. 1\u201325.","DOI":"10.1016\/S0264-410X(00)00037-2"},{"key":"10.1016\/j.virol.2013.11.008_bib62","doi-asserted-by":"crossref","first-page":"24388","DOI":"10.1074\/jbc.M301717200","article-title":"Architecture of the flaviviral replication complex protease, nuclease, and detergents reveal encasement within Double-layered membrane compartments","volume":"278","author":"Uchil","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virol.2013.11.008_bib63","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1006\/viro.1998.9564","article-title":"Noncytopathic flavivirus replicon RNA-based system for expression and delivery of heterologous genes","volume":"255","author":"Varnavski","year":"1999","journal-title":"Virology"},{"key":"10.1016\/j.virol.2013.11.008_bib64","doi-asserted-by":"crossref","first-page":"10960","DOI":"10.1128\/JVI.78.20.10960-10966.2004","article-title":"Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome","volume":"78","author":"Varnum","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib65","doi-asserted-by":"crossref","first-page":"11977","DOI":"10.1128\/JVI.00432-12","article-title":"Identification of RNA-protein interaction networks involved in the norovirus life cycle","volume":"86","author":"Vashist","year":"2012","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib66","doi-asserted-by":"crossref","first-page":"5815","DOI":"10.1128\/JVI.00011-09","article-title":"DDX3 DEAD-Box RNA helicase inhibits hepatitis B virus reverse transcription by incorporation into nucleocapsids","volume":"83","author":"Wang","year":"2009","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib67","doi-asserted-by":"crossref","first-page":"e1000986","DOI":"10.1371\/journal.ppat.1000986","article-title":"Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion","volume":"6","author":"Wang","year":"2010","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2013.11.008_bib68","doi-asserted-by":"crossref","first-page":"6650","DOI":"10.1128\/jvi.71.9.6650-6661.1997","article-title":"Ultrastructure of Kunjin virus-infected cells: colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures","volume":"71","author":"Westaway","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib69","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0065-3527(03)59004-2","article-title":"Kunjin RNA replication and applications ofKunjin replicons","volume":"59","author":"Westaway","year":"2003","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.virol.2013.11.008_bib70","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1146\/annurev.ge.27.120193.002033","article-title":"Genetics of poliovirus","volume":"27","author":"Wimmer","year":"1993","journal-title":"Annu. Rev. Genet."},{"key":"10.1016\/j.virol.2013.11.008_bib71","doi-asserted-by":"crossref","first-page":"8571","DOI":"10.1128\/JVI.00392-10","article-title":"The cellular RNA helicase DDX1 interacts with coronavirus nonstructural protein 14 and enhances viral replication","volume":"84","author":"Xu","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib72","doi-asserted-by":"crossref","first-page":"5571","DOI":"10.1128\/JVI.01933-10","article-title":"The capsid-binding nucleolar helicase DDX56 is important for infectivity of West Nile virus","volume":"85","author":"Xu","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib73","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.virol.2012.08.011","article-title":"The helicase activity of DDX56 is required for its role in assembly of infectious West Nile virus particles","volume":"433","author":"Xu","year":"2012","journal-title":"Virology"},{"key":"10.1016\/j.virol.2013.11.008_bib74","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.cell.2004.09.029","article-title":"Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function","volume":"119","author":"Yedavalli","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.virol.2013.11.008_bib75","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s10822-009-9263-6","article-title":"Identification of novel target sites and an inhibitor of the dengue virus E protein","volume":"23","author":"Yennamalli","year":"2009","journal-title":"J. Comput. Aid. Mol. Des."},{"key":"10.1016\/j.virol.2013.11.008_bib76","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.antiviral.2009.02.187","article-title":"Inhibition of Japanese encephalitis virus replication by peptide nucleic acids targeting cis-acting elements on the plus-and minus-strands of viral RNA","volume":"82","author":"Yoo","year":"2009","journal-title":"Antivir. Res."},{"key":"10.1016\/j.virol.2013.11.008_bib77","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1128\/JVI.73.4.2841-2853.1999","article-title":"Hepatitis C virus core protein interacts with cellular putative RNA helicase","volume":"73","author":"You","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2013.11.008_bib78","doi-asserted-by":"crossref","first-page":"15581","DOI":"10.1074\/jbc.M010923200","article-title":"In vitro RNA synthesis from exogenous dengue viral RNA templates requires long range interactions between 5\u2032- and 3\u2032-terminal regions that influence RNA structure","volume":"276","author":"You","year":"2001","journal-title":"J. Biol. Chem."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682213006211?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682213006211?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:22:10Z","timestamp":1758586930000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682213006211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":77,"alternative-id":["S0042682213006211"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2013.11.008","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cellular DDX3 regulates Japanese encephalitis virus replication by interacting with viral un-translated regions","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2013.11.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}