{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T14:33:56Z","timestamp":1788878036783,"version":"build-2803163510"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,1,15]],"date-time":"2018-01-15T00:00:00Z","timestamp":1515974400000},"content-version":"vor","delay-in-days":379,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.virol.2016.11.010","type":"journal-article","created":{"date-parts":[[2016,11,26]],"date-time":"2016-11-26T19:46:40Z","timestamp":1480189600000},"page":"107-114","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["A homolog of the variola virus B22 membrane protein contributes to ectromelia virus pathogenicity in the mouse footpad model"],"prefix":"10.1016","volume":"501","author":[{"given":"Sara E.","family":"Reynolds","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia L.","family":"Earl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahnaz","family":"Minai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Moss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virol.2016.11.010_bib1","doi-asserted-by":"crossref","first-page":"e1004123","DOI":"10.1371\/journal.ppat.1004123","article-title":"T cell inactivation by poxviral B22 family proteins increases viral virulence","volume":"10","author":"Alzhanova","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2016.11.010_bib2","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.virol.2003.11.015","article-title":"Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model","volume":"318","author":"Buller","year":"2004","journal-title":"Virology"},{"key":"10.1016\/j.virol.2016.11.010_bib3","doi-asserted-by":"crossref","first-page":"9057","DOI":"10.1073\/pnas.0402949101","article-title":"Polarized type 1 cytokine response and cell-mediated immunity determine genetic resistance to mousepox","volume":"101","author":"Chaudhri","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.virol.2016.11.010_bib4","doi-asserted-by":"crossref","DOI":"10.1002\/9780471729259.mc14a03s39","article-title":"Preparation of cell cultures and vaccinia virus stocks","volume":"39","author":"Cotter","year":"2015","journal-title":"Curr. Protoc. Microbiol"},{"key":"10.1016\/j.virol.2016.11.010_bib5","series-title":"Fields Virology","first-page":"2160","article-title":"Poxviruses","author":"Damon","year":"2013"},{"key":"10.1016\/j.virol.2016.11.010_bib6","doi-asserted-by":"crossref","first-page":"2645","DOI":"10.1099\/vir.0.81090-0","article-title":"Ectromelia virus: the causative agent of mousepox","volume":"86","author":"Esteban","year":"2005","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2016.11.010_bib7","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/S0140-6736(48)91599-2","article-title":"The pathogenesis of the acute exanthems; an interpretation based on experimental investigations with mousepox; infectious ectromelia of mice","volume":"2","author":"Fenner","year":"1948","journal-title":"Lancet"},{"key":"10.1016\/j.virol.2016.11.010_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/icb.1949.1","article-title":"Studies in mousepox, infectious ectromelia of mice; quantitative investigations on the spread of virus through the host in actively and passively immunized animals","volume":"27","author":"Fenner","year":"1949","journal-title":"Aust. J. Exp. Biol. Med Sci."},{"key":"10.1016\/j.virol.2016.11.010_bib9","doi-asserted-by":"crossref","first-page":"9348","DOI":"10.1128\/JVI.01174-15","article-title":"Salmon gill poxvirus, the deepest representative of the chordopoxvirinae","volume":"89","author":"Gjessing","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2016.11.010_bib10","first-page":"16","article-title":"Mousepox in inbred mice innately resistant or susceptible to lethal infection with ectromelia virus. II. Pathogenesis","volume":"37","author":"Jacoby","year":"1987","journal-title":"Lab. Anim. Sci."},{"key":"10.1016\/j.virol.2016.11.010_bib11","first-page":"16","article-title":"Mousepox in inbred mice innately resistant or susceptible to lethal infection with ectromelia virus. II. Pathogenesis","volume":"37","author":"Jacoby","year":"1987","journal-title":"Lab Anim. Sci."},{"key":"10.1016\/j.virol.2016.11.010_bib12","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1002\/path.1700330317","article-title":"Infectious Ectromelia. A Hitherto undescribed virus disease of mice","volume":"33","author":"Marchal","year":"1930","journal-title":"J. Path. Bact."},{"key":"10.1016\/j.virol.2016.11.010_bib13","doi-asserted-by":"crossref","first-page":"11170","DOI":"10.1128\/JVI.00256-11","article-title":"The Ectromelia virus SPI-2 protein causes lethal mousepox by preventing NK cell responses","volume":"85","author":"Melo-Silva","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2016.11.010_bib14","first-page":"5","article-title":"Poxvirus DNA replication","author":"Moss","year":"2013","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.virol.2016.11.010_bib15","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1159\/000322101","article-title":"Orthopox viruses: infections in humans","volume":"37","author":"Pauli","year":"2010","journal-title":"Transfus. Med Hemother"},{"key":"10.1016\/j.virol.2016.11.010_bib16","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.virol.2015.04.014","article-title":"Characterization of a large, proteolytically processed cowpox virus membrane glycoprotein conserved in most chordopoxviruses","volume":"483","author":"Reynolds","year":"2015","journal-title":"Virology"},{"key":"10.1016\/j.virol.2016.11.010_bib17","first-page":"289","article-title":"Mouse models for studying orthopoxvirus respiratory infections","volume":"269","author":"Schriewer","year":"2004","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.virol.2016.11.010_bib18","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1099\/vir.0.055921-0","article-title":"Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity","volume":"94","author":"Smith","year":"2013","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2016.11.010_bib19","first-page":"41","article-title":"Kinetics of ectromelia virus (mousepox) transmission and clinical response in C57BL\/6j, BALB\/cByj and AKR\/J inbred mice","volume":"35","author":"Wallace","year":"1985","journal-title":"Lab. Anim. Sci."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682216303555?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682216303555?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:39:20Z","timestamp":1758587960000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682216303555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":19,"alternative-id":["S0042682216303555"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2016.11.010","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A homolog of the variola virus B22 membrane protein contributes to ectromelia virus pathogenicity in the mouse footpad model","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2016.11.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}