{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T10:24:14Z","timestamp":1790763854098,"version":"4.1.0"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,1,15]],"date-time":"2019-01-15T00:00:00Z","timestamp":1547510400000},"content-version":"vor","delay-in-days":379,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003074","name":"Agencia Nacional de Promoci\u00c3\u00b3n Cient\u00c3\u00adfica y Tecnol\u00c3\u00b3gica","doi-asserted-by":"publisher","award":["BID-PICT 517"],"award-info":[{"award-number":["BID-PICT 517"]}],"id":[{"id":"10.13039\/501100003074","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009613","name":"Centro de Investigaciones Energ\u00c3\u00a9ticas, Medioambientales y Tecnol\u00c3\u00b3gicas","doi-asserted-by":"publisher","award":["PIP-0293"],"award-info":[{"award-number":["PIP-0293"]}],"id":[{"id":"10.13039\/501100009613","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005363","name":"Universidad de Buenos Aires","doi-asserted-by":"publisher","award":["20020120100033"],"award-info":[{"award-number":["20020120100033"]}],"id":[{"id":"10.13039\/501100005363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.virol.2017.10.012","type":"journal-article","created":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T18:47:05Z","timestamp":1512154025000},"page":"216-229","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["The interplay between viperin antiviral activity, lipid droplets and Jun\u00edn mammarenavirus multiplication"],"prefix":"10.1016","volume":"514","author":[{"given":"Jos\u00e9 R.","family":"Pe\u00f1a C\u00e1rcamo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda L.","family":"Morell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia A.","family":"V\u00e1zquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sezen","family":"Vatansever","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arunkumar S.","family":"Upadhyay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna K.","family":"\u00d6verby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra M.","family":"Cordo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cybele C.","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.virol.2017.10.012_bib1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.antiviral.2009.07.001","article-title":"Inhibition of Junin virus replication by small interfering RNAs","volume":"84","author":"Artuso","year":"2009","journal-title":"Antivir. Res."},{"key":"10.1016\/j.virol.2017.10.012_bib2","doi-asserted-by":"crossref","first-page":"19928","DOI":"10.1038\/srep19928","article-title":"Emerging role of lipid droplets in Aedesaegypti immune response against bacteria and Dengue virus","volume":"6","author":"Barletta","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2017.10.012_bib3","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S1387-2656(05)11004-7","article-title":"Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction","volume":"11","author":"Berridge","year":"2005","journal-title":"Biotechnol. Annu. Rev."},{"key":"10.1016\/j.virol.2017.10.012_bib4","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1084\/jem.186.6.909","article-title":"Eosinophil lipid bodies: specific, inducible intracellular sites for enhanced eicosanoid formation","volume":"186","author":"Bozza","year":"1997","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.virol.2017.10.012_bib5","doi-asserted-by":"crossref","first-page":"46835","DOI":"10.1074\/jbc.M409340200","article-title":"Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes","volume":"279","author":"Brasaemle","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virol.2017.10.012_bib6","doi-asserted-by":"crossref","first-page":"11548","DOI":"10.1128\/JVI.01773-12","article-title":"Viperin, MTAP44, and protein kinase R contribute to the interferon-induced inhibition of Bunyamwera Orthobunyavirus replication","volume":"86","author":"Carlton-Smith","year":"2012","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib7","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1002\/jcb.10266","article-title":"Oleic acid-induced PKC isozyme translocation in RAW 264.7 macrophages","volume":"86","author":"Chen","year":"2002","journal-title":"J. Cell Biochem."},{"key":"10.1016\/j.virol.2017.10.012_bib8","doi-asserted-by":"crossref","first-page":"15125","DOI":"10.1073\/pnas.011593298","article-title":"Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus","volume":"98","author":"Chin","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.virol.2017.10.012_bib9","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/bioinformatics\/btg371","article-title":"ClusPro: an automated docking and discrimination method for the prediction of protein complexes","volume":"20","author":"Comeau","year":"2004","journal-title":"Bioinformatics"},{"key":"10.1016\/j.virol.2017.10.012_bib10","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S1286-4579(99)80060-4","article-title":"Myristic acid analogs are inhibitors of Junin virus replication","volume":"8","author":"Cordo","year":"1999","journal-title":"Microbes Infect."},{"key":"10.1016\/j.virol.2017.10.012_bib11","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1016\/j.bbrc.2012.12.053","article-title":"Membrane localization of Jun\u00edn virus glycoproteins requires cholesterol and cholesterol rich membranes","volume":"430","author":"Cordo","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.virol.2017.10.012_bib12","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1038\/sj.embor.7400002","article-title":"Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor","volume":"4","author":"Eichler","year":"2003","journal-title":"EMBO Rep."},{"key":"10.1016\/j.virol.2017.10.012_bib13","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.antiviral.2007.10.010","article-title":"Treatment of Argentine hemorrhagic fever","volume":"78","author":"Enria","year":"2008","journal-title":"Antivir. Res."},{"key":"10.1016\/j.virol.2017.10.012_bib14","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1128\/JVI.01362-09","article-title":"Z proteins of New World arenaviruses bind RIG-I and interfere with type I interferon induction","volume":"84","author":"Fan","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib15","doi-asserted-by":"crossref","first-page":"6806","DOI":"10.1073\/pnas.1705402114","article-title":"Structural studies of viperin, an antiviral radical SAM enzyme","volume":"114","author":"Fenwick","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"4","key":"10.1016\/j.virol.2017.10.012_bib16","doi-asserted-by":"crossref","DOI":"10.1101\/pdb.prot087379","article-title":"Crystal violet assay for determining viability of cultured cells","author":"Feoktistova","year":"2016","journal-title":"Cold Spring Harb. Protoc."},{"key":"10.1016\/j.virol.2017.10.012_bib17","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1083\/jcb.152.5.1079","article-title":"Caveolin-2 is targeted to lipid droplets, a new \u201cmembrane domain\u201d in the cell","volume":"152","author":"Fujimoto","year":"2001","journal-title":"J. Cell Biol."},{"issue":"1","key":"10.1016\/j.virol.2017.10.012_bib18","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.virusres.2009.03.010","article-title":"Characterization of Jun\u00edn virus particles inactivated by a zinc finger-reactive compound","volume":"143","author":"Garc\u00eda","year":"2009","journal-title":"Virus Res."},{"key":"10.1016\/j.virol.2017.10.012_bib19","doi-asserted-by":"crossref","first-page":"6022","DOI":"10.1038\/ncomms7022","article-title":"Sorting of small infectious virus particles by flow virometry reveals distinct infectivity profiles","volume":"6","author":"Gaudin","year":"2015","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.virol.2017.10.012_bib20","doi-asserted-by":"crossref","first-page":"e0125690","DOI":"10.1371\/journal.pone.0125690","article-title":"Cellular promyelocytic leukemia protein is an important dengue virus restriction factor","volume":"10","author":"Giovannoni","year":"2015","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.virol.2017.10.012_bib21","doi-asserted-by":"crossref","first-page":"e1137","DOI":"10.1371\/journal.pntd.0001137","article-title":"Tacaribe virus but not junin virus infection induces cytokine release from primary human monocytes and macrophages","volume":"5","author":"Groseth","year":"2011","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"6","key":"10.1016\/j.virol.2017.10.012_bib22","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1016\/j.jmb.2013.10.019","article-title":"The role of viperin in the innate antiviral response","volume":"426","author":"Helbig","year":"2014","journal-title":"J. Mol. Biol."},{"issue":"4","key":"10.1016\/j.virol.2017.10.012_bib23","doi-asserted-by":"crossref","first-page":"e2178","DOI":"10.1371\/journal.pntd.0002178","article-title":"Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin","volume":"18","author":"Helbig","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.virol.2017.10.012_bib24","doi-asserted-by":"crossref","first-page":"20452","DOI":"10.1073\/pnas.0911679106","article-title":"The antiviral protein, viperin, localizes to lipid droplets via its N-terminal amphipathic alpha-helix","volume":"106","author":"Hinson","year":"2009","journal-title":"Proc. Natl. Acad. Sci. Usa."},{"key":"10.1016\/j.virol.2017.10.012_bib25","doi-asserted-by":"crossref","first-page":"4705","DOI":"10.1074\/jbc.M807261200","article-title":"The N-terminal amphipathic alpha-helix of viperin mediates localization to the cytosolic face of the endoplasmic reticulum and inhibits protein secretion","volume":"284","author":"Hinson","year":"2009","journal-title":"J. Biol. Chem."},{"issue":"10","key":"10.1016\/j.virol.2017.10.012_bib26","doi-asserted-by":"crossref","first-page":"5723","DOI":"10.4049\/jimmunol.0903752","article-title":"Viperin is highly induced in neutrophils and macrophages during acute and chronic lymphocytic choriomeningitis virus infection","volume":"184","author":"Hinson","year":"2010","journal-title":"J. Immunol."},{"issue":"5","key":"10.1016\/j.virol.2017.10.012_bib27","doi-asserted-by":"crossref","first-page":"e1659","DOI":"10.1371\/journal.pntd.0001659","article-title":"Jun\u00edn Virus Infection Activates the Type I Interferon Pathway in a RIG-I-Dependent Manner","volume":"6","author":"Huang","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.virol.2017.10.012_bib28","doi-asserted-by":"crossref","first-page":"e2933","DOI":"10.1371\/journal.pntd.0002933","article-title":"Potent inhibition of Jun\u00edn virus infection by interferon in murine cells","volume":"8","author":"Huang","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.virol.2017.10.012_bib29","doi-asserted-by":"crossref","first-page":"7079","DOI":"10.1128\/JVI.00526-15","article-title":"Highly pathogenic new world and old world human arenaviruses induce distinct interferon responses in human cells","volume":"89","author":"Huang","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib30","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.immuni.2011.03.012","article-title":"Viperin links lipid bodies to immune defense","volume":"34","author":"Jiang","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.virol.2017.10.012_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2015.10.019","article-title":"SnapShot: antiviral restriction factors","volume":"163","author":"Kluge","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.virol.2017.10.012_bib32","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.tips.2005.09.002","article-title":"The connections between C75 and obesity drug-target pathways","volume":"26","author":"Kuhajda","year":"2005","journal-title":"Trends Pharmacol. Sci."},{"issue":"3","key":"10.1016\/j.virol.2017.10.012_bib33","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1093\/infdis\/149.3.428","article-title":"Endogenous interferon in Argentine hemorrhagic fever","volume":"149","author":"Levis","year":"1984","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2017.10.012_bib34","doi-asserted-by":"crossref","first-page":"3787","DOI":"10.1074\/jbc.M311945200","article-title":"Chinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane traffic","volume":"279","author":"Liu","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virol.2017.10.012_bib35","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1126\/science.288.5475.2379","article-title":"Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors","volume":"288","author":"Loftus","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.virol.2017.10.012_bib36","doi-asserted-by":"crossref","first-page":"26806","DOI":"10.1074\/jbc.M116.751040","article-title":"Does viperin function as a radical S-Adenosyl-L-methionine-dependent enzyme in regulating farnesylpyrophosphate synthase expression and activity?","volume":"291","author":"Makins","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virol.2017.10.012_bib37","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1365-2818.1993.tb03313.x","article-title":"Measurement of co-localization of objects in dual-colour confocal images","volume":"169","author":"Manders","year":"1993","journal-title":"J. Microsc."},{"key":"10.1016\/j.virol.2017.10.012_bib38","doi-asserted-by":"crossref","first-page":"9192","DOI":"10.1128\/JVI.00555-06","article-title":"Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus","volume":"80","author":"Mart\u00ednez-Sobrido","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib39","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1159\/000342473","article-title":"Replication of respiratory syncytial virus is inhibited by the host defense molecule viperin","volume":"5","author":"McGillivary","year":"2013","journal-title":"J. Innate Immun."},{"key":"10.1016\/j.virol.2017.10.012_bib40","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1182\/blood-2012-01-407395","article-title":"HIV-1 infection of human macrophages directly induces viperin which inhibits viral production","volume":"120","author":"Nasr","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.virol.2017.10.012_bib41","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1146\/annurev-pathol-020712-164041","article-title":"Pathogenesis of the viral hemorrhagic fevers","volume":"8","author":"Paessler","year":"2013","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.virol.2017.10.012_bib42","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1002\/jcc.20084","article-title":"UCSF Chimera a visualization system for exploratory research and analysis","volume":"25","author":"Pettersen","year":"2004","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.virol.2017.10.012_bib43","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1093\/bioinformatics\/btu097","article-title":"ZDock server: interactive docking prediction of protein-protein complexes and symmetric multimers","volume":"30","author":"Pierce","year":"2014","journal-title":"Bioinformatics"},{"issue":"6","key":"10.1016\/j.virol.2017.10.012_bib44","doi-asserted-by":"crossref","first-page":"3882","DOI":"10.1128\/JVI.77.6.3882-3887.2003","article-title":"Role of the virus nucleoprotein in the regulation of lymphocytic choriomeningitis virus transcription and RNA replication","volume":"77","author":"Pinschewer","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib45","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1083\/jcb.201311051","article-title":"Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites","volume":"204","author":"Pol","year":"2014","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.virol.2017.10.012_bib46","doi-asserted-by":"crossref","first-page":"6240","DOI":"10.1128\/JVI.00610-15","article-title":"Lymphocytic Choriomeningitis virus differentially affects the virus-induced type I Interferon response and mitochondrial apoptosis mediated by RIG-I\/MAVS","volume":"89","author":"Pythoud","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib47","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1007\/s00705-015-2418-y","article-title":"Past, present, and future of arenavirus taxonomy","volume":"160","author":"Radoshitzky","year":"2015","journal-title":"Arch. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib48","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.physbeh.2005.04.014","article-title":"Fatty acid metabolism as a target for obesity treatment","volume":"85","author":"Ronnett","year":"2005","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.virol.2017.10.012_bib49","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1146\/annurev-cellbio-092910-153958","article-title":"Emerging roles for lipid droplets in immunity and host-pathogen interactions","volume":"28","author":"Saka","year":"2012","journal-title":"Annu. Rev. Cell Dev. Biol."},{"issue":"10","key":"10.1016\/j.virol.2017.10.012_bib50","doi-asserted-by":"crossref","first-page":"e1000632","DOI":"10.1371\/journal.ppat.1000632","article-title":"Dengue virus capsid protein usurps lipid droplets for viral particle formation","volume":"5","author":"Samsa","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2017.10.012_bib51","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1099\/0022-1317-70-5-1125","article-title":"Junin virus monoclonal antibodies: characterization and cross-reactivity with other arenaviruses","volume":"70","author":"Sanchez","year":"1989","journal-title":"J. Gen. Virol."},{"issue":"8","key":"10.1016\/j.virol.2017.10.012_bib52","doi-asserted-by":"crossref","first-page":"e1003497","DOI":"10.1371\/journal.ppat.1003497","article-title":"Viperin regulates cellular lipid metabolism during human cytomegalovirus infection","volume":"9","author":"Seo","year":"2013","journal-title":"PLoS Pathog."},{"issue":"6","key":"10.1016\/j.virol.2017.10.012_bib53","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.chom.2011.11.004","article-title":"Viperin: a multifunctional, interferon-inducible protein that regulates virus replication","volume":"10","author":"Seo","year":"2011","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.virol.2017.10.012_bib54","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1016\/j.bbrc.2009.12.070","article-title":"Structural characterization reveals that viperin is a S-adenosyl-L-methionine (SAM) enzyme","volume":"391","author":"Shaveta","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.virol.2017.10.012_bib55","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1099\/vir.0.040824-0","article-title":"In vivo and in vitro studies on the antiviral activities of viperin against influenza H1N1 virus infection","volume":"93","author":"Tan","year":"2012","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib56","doi-asserted-by":"crossref","first-page":"4447","DOI":"10.1172\/JCI63120","article-title":"Viperin restricts chikungunya virus replication and pathology","volume":"122","author":"Teng","year":"2012","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.virol.2017.10.012_bib57","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1099\/0022-1317-82-1-121","article-title":"Zinc-binding properties of Jun\u00edn virus nucleocapsid protein","volume":"82","author":"Tortorici","year":"2001","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib58","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1111\/cmi.12241","article-title":"Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity","volume":"16","author":"Upadhyay","year":"2014","journal-title":"Cell Microbiol."},{"key":"10.1016\/j.virol.2017.10.012_bib59","doi-asserted-by":"crossref","first-page":"13879","DOI":"10.1074\/jbc.M117.780122","article-title":"Cellular requirements for iron-sulfur cluster insertion into the antiviral radical SAM protein viperin","volume":"292","author":"Upadhyay","year":"2017","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virol.2017.10.012_bib60","doi-asserted-by":"crossref","first-page":"4475","DOI":"10.1038\/s41598-017-04138-1","article-title":"Viperin is an important host restriction factor in control of Zika virus infection","volume":"7","author":"Van der Hoek","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2017.10.012_bib61","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1096\/fj.06-6711com","article-title":"Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies","volume":"21","author":"Wan","year":"2007","journal-title":"FASEB J."},{"key":"10.1016\/j.virol.2017.10.012_bib62","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/B978-0-12-408051-5.00007-3","article-title":"Analysis of lipid droplets in hepatocytes","volume":"116","author":"Wang","year":"2013","journal-title":"Methods Cell Biol."},{"key":"10.1016\/j.virol.2017.10.012_bib63","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1099\/vir.0.033860-0","article-title":"Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein hVAP-33","volume":"93","author":"Wang","year":"2012","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib64","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.chom.2007.06.009","article-title":"The interferon-inducible protein viperin inhibits influenza virus release by perturbing lipid rafts","volume":"2","author":"Wang","year":"2007","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.virol.2017.10.012_bib65","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.1128\/JVI.03349-14","article-title":"The Z proteins of pathogenic but not nonpathogenic arenaviruses inhibit RIG-I-like receptor-dependent interferon production","volume":"89","author":"Xing","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib66","doi-asserted-by":"crossref","first-page":"10783","DOI":"10.1128\/JVI.78.19.10783-10792.2004","article-title":"The signal peptide of the Jun\u00edn arenavirus envelope glycoprotein is myristoylated and forms an essential subunit of the mature G1-G2 complex","volume":"78","author":"York","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2017.10.012_bib67","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1182\/blood.V95.3.1078.003k16_1078_1085","article-title":"Phosphatidylinositide 3-kinase localizes to cytoplasmic lipid bodies in human polymorphonuclear leukocytes and other myeloid-derived cells","volume":"95","author":"Yu","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.virol.2017.10.012_bib68","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1099\/vir.0.055053-0","article-title":"Crystal structure of Junin virus nucleoprotein","volume":"94","author":"Zhang","year":"2013","journal-title":"J. Gen. Virol."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682217303616?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682217303616?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:45:23Z","timestamp":1758588323000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682217303616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":68,"alternative-id":["S0042682217303616"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2017.10.012","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The interplay between viperin antiviral activity, lipid droplets and Jun\u00edn mammarenavirus multiplication","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2017.10.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}