{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T12:45:32Z","timestamp":1774442732397,"version":"3.50.1"},"reference-count":96,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000097","name":"NCRR","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"crossref"}]},{"name":"NIH","award":["RR023343"],"award-info":[{"award-number":["RR023343"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.virol.2018.04.007","type":"journal-article","created":{"date-parts":[[2018,4,22]],"date-time":"2018-04-22T13:09:17Z","timestamp":1524402557000},"page":"106-120","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Macaque homologs of Kaposi's sarcoma-associated herpesvirus (KSHV) infect germinal center lymphoid cells, epithelial cells in skin and gastrointestinal tract and gonadal germ cells in naturally infected macaques"],"prefix":"10.1016","volume":"519","author":[{"given":"Helle","family":"Bielefeldt-Ohmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Gregory","family":"Bruce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kellie","family":"Howard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minako","family":"Ikoma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret E.","family":"Thouless","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7646-0028","authenticated-orcid":false,"given":"Timothy M.","family":"Rose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.virol.2018.04.007_bib1","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/j.1440-1827.2006.02017.x","article-title":"Distinct expression of Kaposi's sarcoma-associated herpesvirus-encoded proteins in Kaposi's sarcoma and multicentric Castleman's disease","volume":"56","author":"Abe","year":"2006","journal-title":"Pathol. Int"},{"key":"10.1016\/j.virol.2018.04.007_bib2","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0092-8674(02)00628-1","article-title":"Integrin alpha3beta1 (CD 49c\/29) is a cellular receptor for Kaposi's sarcoma-associated herpesvirus (KSHV\/HHV-8) entry into the target cells","volume":"108","author":"Akula","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.virol.2018.04.007_bib3","doi-asserted-by":"crossref","first-page":"3388","DOI":"10.1128\/JVI.74.7.3388-3398.2000","article-title":"The primary sequence of rhesus monkey rhadinovirus isolate 26-95: sequence similarities to Kaposi's sarcoma-associated herpesvirus and rhesus monkey rhadinovirus isolate 17577","volume":"74","author":"Alexander","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib4","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.virol.2011.06.015","article-title":"Multiple phosphorylation sites at the C-terminus regulate nuclear import of HCMV DNA polymerase processivity factor ppUL44","volume":"417","author":"Alvisi","year":"2011","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib5","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1128\/JVI.74.1.584-590.2000","article-title":"Species specificity of macaque rhadinovirus glycoprotein B sequences","volume":"74","author":"Auerbach","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib6","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1515\/BMC.2011.044","article-title":"Origin and function of embryonic Sertoli cells","volume":"2","author":"Barrionuevo","year":"2011","journal-title":"Biomol. Concepts"},{"key":"10.1016\/j.virol.2018.04.007_bib7","doi-asserted-by":"crossref","first-page":"6474","DOI":"10.1128\/JVI.77.11.6474-6481.2003","article-title":"Host range of Kaposi's sarcoma-associated herpesvirus in cultured cells","volume":"77","author":"Bechtel","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib8","doi-asserted-by":"crossref","first-page":"7874","DOI":"10.1128\/JVI.73.9.7874-7876.1999","article-title":"Rhesus rhadinovirus establishes a latent infection in B lymphocytes in vivo","volume":"73","author":"Bergquam","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib9","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1354\/vp.42-3-391","article-title":"Intestinal stromal tumors in a simian immunodeficiency virus-infected, simian retrovirus-2 negative rhesus macaque (Macaca mulatta)","volume":"42","author":"Bielefeldt-Ohmann","year":"2005","journal-title":"Vet. Pathol."},{"key":"10.1016\/j.virol.2018.04.007_bib10","doi-asserted-by":"crossref","first-page":"3644","DOI":"10.1128\/JVI.80.7.3644-3649.2006","article-title":"Infection and persistence of rhesus monkey rhadinovirus in immortalized B-cell lines","volume":"80","author":"Bilello","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib11","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1097\/00002030-200006160-00009","article-title":"The restricted cellular host range of human herpesvirus 8","volume":"14","author":"Blackbourn","year":"2000","journal-title":"AIDS"},{"key":"10.1016\/j.virol.2018.04.007_bib12","doi-asserted-by":"crossref","first-page":"7963","DOI":"10.1128\/jvi.71.10.7963-7968.1997","article-title":"Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8","volume":"71","author":"Blasig","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib13","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1038\/nm1295-1274","article-title":"Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells","volume":"1","author":"Boshoff","year":"1995","journal-title":"Nat. Med"},{"key":"10.1016\/j.virol.2018.04.007_bib14","doi-asserted-by":"crossref","first-page":"3529","DOI":"10.1099\/vir.0.82339-0","article-title":"High levels of retroperitoneal fibromatosis (RF)-associated herpesvirus in RF lesions in macaques are associated with ORF73 LANA expression in spindleoid tumour cells","volume":"87","author":"Bruce","year":"2006","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib15","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1186\/1743-422X-6-205","article-title":"The ORF59 DNA polymerase processivity factor homologs of Old World primate RV2 rhadinoviruses are highly conserved nuclear antigens expressed in differentiated epithelium in infected macaques","volume":"6","author":"Bruce","year":"2009","journal-title":"Virol. J."},{"key":"10.1016\/j.virol.2018.04.007_bib16","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1743-422X-2-2","article-title":"Development of a real-time QPCR assay for the detection of RV2 lineage-specific rhadinoviruses in macaques and baboons","volume":"2","author":"Bruce","year":"2005","journal-title":"Virol. J."},{"key":"10.1016\/j.virol.2018.04.007_bib17","doi-asserted-by":"crossref","first-page":"e1002962","DOI":"10.1371\/journal.ppat.1002962","article-title":"Macaque homologs of EBV and KSHV show uniquely different associations with simian AIDS-related lymphomas","volume":"8","author":"Bruce","year":"2012","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2018.04.007_bib18","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.virol.2016.04.003","article-title":"Conservation of the glycoprotein B homologs of the Kaposis sarcoma-associated herpesvirus (KSHV\/HHV8) and old world primate rhadinoviruses of chimpanzees and macaques","volume":"494","author":"Bruce","year":"2016","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib19","doi-asserted-by":"crossref","first-page":"13676","DOI":"10.1128\/JVI.02331-13","article-title":"Next-generation sequence analysis of the genome of RFHVMn, the macaque homolog of Kaposi's sarcoma (KS)-associated herpesvirus, from a KS-like tumor of a pig-tailed macaque","volume":"87","author":"Bruce","year":"2013","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib20","doi-asserted-by":"crossref","first-page":"3888","DOI":"10.1128\/JVI.03597-14","article-title":"Complete genome sequence of Pig-tailed macaque rhadinovirus 2 and its evolutionary relationship with rhesus macaque rhadinovirus and human herpesvirus 8\/Kaposi's sarcoma-associated herpesvirus","volume":"89","author":"Bruce","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib21","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.virol.2006.06.022","article-title":"RFHVMn ORF73 is structurally related to the KSHV ORF73 latency-associated nuclear antigen (LANA) and is expressed in retroperitoneal fibromatosis (RF) tumor cells","volume":"354","author":"Burnside","year":"2006","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib22","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1056\/NEJM199505043321802","article-title":"Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas [see comments]","volume":"332","author":"Cesarman","year":"1995","journal-title":"N. Engl. J. Med"},{"key":"10.1016\/j.virol.2018.04.007_bib23","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ijporl.2005.04.030","article-title":"Detection of herpesvirus type 8 (HHV8) in children's tonsils and adenoids by immunohistochemistry and in situ hybridization","volume":"70","author":"Chagas","year":"2006","journal-title":"Int J. Pediatr. Otorhinolaryngol."},{"key":"10.1016\/j.virol.2018.04.007_bib24","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1126\/science.7997879","article-title":"Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma [see comments]","volume":"266","author":"Chang","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.virol.2018.04.007_bib25","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.virol.2005.06.017","article-title":"Processivity factor of KSHV contains a nuclear localization signal and binding domains for transporting viral DNA polymerase into the nucleus","volume":"340","author":"Chen","year":"2005","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib26","doi-asserted-by":"crossref","first-page":"e18920","DOI":"10.1371\/journal.pone.0018920","article-title":"Conservation of complex nuclear localization signals utilizing classical and non-classical nuclear import pathways in LANA homologs of KSHV and RFHV","volume":"6","author":"Cherezova","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.virol.2018.04.007_bib27","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1093\/oxfordjournals.bmb.a072515","article-title":"Viral persistence and disease: cytopathology in the absence of cytolysis","volume":"47","author":"de la Torre","year":"1991","journal-title":"Br. Med Bull."},{"key":"10.1016\/j.virol.2018.04.007_bib28","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.virol.2013.10.013","article-title":"A critical Sp1 element in the rhesus rhadinovirus (RRV) Rta promoter confers high-level activity that correlates with cellular permissivity for viral replication","volume":"448","author":"DeMaster","year":"2014","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib29","doi-asserted-by":"crossref","first-page":"9764","DOI":"10.1128\/jvi.71.12.9764-9769.1997","article-title":"A herpesvirus of rhesus monkeys related to the human Kaposi's sarcoma-associated herpesvirus","volume":"71","author":"Desrosiers","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib30","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1128\/JVI.79.5.3127-3138.2005","article-title":"The latency-associated nuclear antigen of rhesus monkey rhadinovirus inhibits viral replication through repression of Orf50\/Rta transcriptional activation","volume":"79","author":"DeWire","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib31","doi-asserted-by":"crossref","first-page":"4546","DOI":"10.1073\/pnas.96.8.4546","article-title":"Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma","volume":"96","author":"Dupin","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.virol.2018.04.007_bib32","doi-asserted-by":"crossref","first-page":"2971","DOI":"10.1172\/JCI119492","article-title":"In situ polymerase chain reaction-based localization studies support role of human herpesvirus-8 as the cause of two AIDS-related neoplasms: kaposi's sarcoma and body cavity lymphoma","volume":"99","author":"Foreman","year":"1997","journal-title":"J. Clin. Invest"},{"key":"10.1016\/j.virol.2018.04.007_bib33","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/0140-6736(90)93392-3","article-title":"Human herpesvirus 6 in salivary glands","volume":"336","author":"Fox","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.virol.2018.04.007_bib34","doi-asserted-by":"crossref","first-page":"3162","DOI":"10.4049\/jimmunol.137.10.3162","article-title":"Detection of Epstein-Barr virus-associated antigens and DNA in salivary gland biopsies from patients with Sjogren's syndrome","volume":"137","author":"Fox","year":"1986","journal-title":"J. Immunol."},{"key":"10.1016\/j.virol.2018.04.007_bib35","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.virol.2014.06.035","article-title":"KSHV attachment and entry are dependent on alphaVbeta3 integrin localized to specific cell surface microdomains and do not correlate with the presence of heparan sulfate","volume":"464\u2013465","author":"Garrigues","year":"2014","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib36","doi-asserted-by":"crossref","first-page":"e01532-17","DOI":"10.1128\/JVI.01532-17","article-title":"Full-length isoforms of KSHV LANA accumulate in the cytoplasm of cells undergoing the lytic cycle of replication","volume":"91","author":"Garrigues","year":"2017","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib37","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1128\/JVI.01673-07","article-title":"Integrin alphaVbeta3 Binds to the RGD motif of glycoprotein B of Kaposi's sarcoma-associated herpesvirus and functions as an RGD-dependent entry receptor","volume":"82","author":"Garrigues","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib38","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.virol.2014.01.006","article-title":"KSHV cell attachment sites revealed by ultra sensitive tyramide signal amplification (TSA) localize to membrane microdomains that are up-regulated on mitotic cells","volume":"452\u2013453","author":"Garrigues","year":"2014","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib39","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1128\/JVI.74.3.1572-1577.2000","article-title":"Two distinct gamma-2 herpesviruses in African green monkeys: a second gamma-2 herpesvirus lineage among old world primates?","volume":"74","author":"Greensill","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib40","doi-asserted-by":"crossref","first-page":"e1003360","DOI":"10.1371\/journal.ppat.1003360","article-title":"Rhesus monkey rhadinovirus uses eph family receptors for entry into B cells and endothelial cells but not fibroblasts","volume":"9","author":"Hahn","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2018.04.007_bib41","doi-asserted-by":"crossref","first-page":"8724","DOI":"10.1128\/JVI.01392-14","article-title":"Binding of the Kaposi's sarcoma-associated herpesvirus to the ephrin binding surface of the EphA2 receptor and its inhibition by a small molecule","volume":"88","author":"Hahn","year":"2014","journal-title":"J. Virol."},{"issue":"152\u2013164","key":"10.1016\/j.virol.2018.04.007_bib42","article-title":"ORF73 LANA homologs of RRV and MneRV2 contain an extended RGG\/RG-rich nuclear and nucleolar localization signal that interacts directly with importin beta1 for non-classical nuclear import","volume":"511","author":"Howard","year":"2017","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib43","doi-asserted-by":"crossref","first-page":"F15","DOI":"10.1097\/00002030-199702000-00001","article-title":"Detection of human herpesvirus 8 DNA in semen from HIV-infected individuals but not healthy semen donors","volume":"11","author":"Howard","year":"1997","journal-title":"AIDS"},{"key":"10.1016\/j.virol.2018.04.007_bib44","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0140-6736(95)90641-X","article-title":"Human herpesvirus-like nucleic acid in various forms of Kaposi's sarcoma","volume":"345","author":"Huang","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.virol.2018.04.007_bib45","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1600-0684.2004.00079.x","article-title":"Perinatal transmission of SHIV-SF162P3 in Macaca nemestrina","volume":"33","author":"Jayaraman","year":"2004","journal-title":"J. Med Primatol."},{"key":"10.1016\/j.virol.2018.04.007_bib46","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1128\/JVI.01759-06","article-title":"Evidence for persistent, occult infection in neonatal macaques following perinatal transmission of simian-human immunodeficiency virus SF162P3","volume":"81","author":"Jayaraman","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib47","doi-asserted-by":"crossref","first-page":"13769","DOI":"10.1128\/JVI.79.21.13769-13777.2005","article-title":"Activation of Kaposi's sarcoma-associated herpesvirus lytic gene expression during epithelial differentiation","volume":"79","author":"Johnson","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib48","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1126\/science.1120878","article-title":"Kaposi's sarcoma-associated herpesvirus fusion-entry receptor: cystine transporter xCT","volume":"311","author":"Kaleeba","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.virol.2018.04.007_bib49","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1006\/viro.2000.0196","article-title":"Expression and localization of human herpesvirus 8-encoded proteins in primary effusion lymphoma, Kaposi's sarcoma, and multicentric Castleman's disease","volume":"269","author":"Katano","year":"2000","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib50","doi-asserted-by":"crossref","first-page":"5149","DOI":"10.1128\/JVI.73.6.5149-5155.1999","article-title":"Characterization of monoclonal antibodies raised against the latent nuclear antigen of human herpesvirus 8","volume":"73","author":"Kellam","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib51","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S1386-6532(99)00077-3","article-title":"Human herpesvirus type 8 in salivary gland tumors","volume":"16","author":"Klussmann","year":"2000","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib52","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1034\/j.1600-0714.2003.00092.x","article-title":"Detection of HHV-8 sequences and antigens in a MALT lymphoma associated with Sjogren's syndrome","volume":"32","author":"Klussmann","year":"2003","journal-title":"J. Oral. Pathol. Med"},{"key":"10.1016\/j.virol.2018.04.007_bib53","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1086\/514045","article-title":"Frequent detection of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in saliva of human immunodeficiency virus-infected men: clinical and immunologic correlates","volume":"176","author":"Koelle","year":"1997","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2018.04.007_bib54","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/0140-6736(90)92874-H","article-title":"Latent herpesvirus-6 in salivary and bronchial glands","volume":"336","author":"Krueger","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.virol.2018.04.007_bib55","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/35025145","article-title":"KSHV-like herpesviruses in chimps and gorillas","volume":"407","author":"Lacoste","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.virol.2018.04.007_bib56","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1101\/gr.158601","article-title":"A novel gamma 2-herpesvirus of the Rhadinovirus 2 lineage in chimpanzees","volume":"11","author":"Lacoste","year":"2001","journal-title":"Genome Res"},{"key":"10.1016\/j.virol.2018.04.007_bib57","doi-asserted-by":"crossref","first-page":"11993","DOI":"10.1128\/JVI.74.24.11993-11999.2000","article-title":"Simian Homologues of Human Gamma-2 and Betaherpesviruses in Mandrill and Drill Monkeys","volume":"74","author":"Lacoste","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib58","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1128\/jvi.76.5.2440-2448.2002","article-title":"De novo infection and serial transmission of Kaposi's sarcoma-associated herpesvirus in cultured endothelial cells","volume":"76","author":"Lagunoff","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib59","doi-asserted-by":"crossref","first-page":"10320","DOI":"10.1128\/JVI.73.12.10320-10328.1999","article-title":"Experimental infection of rhesus and pig-tailed macaques with macaque rhadinoviruses","volume":"73","author":"Mansfield","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib60","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/j.1600-0684.1993.tb00690.x","article-title":"Viral persistence of simian type D retrovirus (SRV-2\/W) in naturally infected pigtailed macaques (Macaca nemestrina)","volume":"22","author":"Moazed","year":"1993","journal-title":"J. Med Primatol."},{"key":"10.1016\/j.virol.2018.04.007_bib61","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1056\/NEJM199605023341805","article-title":"Kaposi's sarcoma-associated herpesvirus DNA sequences in prostate tissue and human semen","volume":"334","author":"Monini","year":"1996","journal-title":"N. Engl. J. Med"},{"key":"10.1016\/j.virol.2018.04.007_bib62","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1093\/oxfordjournals.jncimonographs.a024179","article-title":"Novel organizational features, captured cellular genes, and strain variability within the genome of KSHV\/HHV8","author":"Nicholas","year":"1998","journal-title":"J. Natl. Cancer Inst. Monogr."},{"key":"10.1016\/j.virol.2018.04.007_bib63","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1126\/science.7146898","article-title":"Virus-induced alterations in homeostasis: alteration in differentiated functions of infected cells in vivo","volume":"218","author":"Oldstone","year":"1982","journal-title":"Science"},{"key":"10.1016\/j.virol.2018.04.007_bib64","doi-asserted-by":"crossref","first-page":"F35","DOI":"10.1097\/00002030-199705000-00001","article-title":"Visualization of human herpesvirus type 8 in Kaposi's sarcoma by light and transmission electron microscopy","volume":"11","author":"Orenstein","year":"1997","journal-title":"AIDS"},{"issue":"Suppl 1","key":"10.1016\/j.virol.2018.04.007_bib65","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1600-0684.2009.00369.x","article-title":"Viral interleukin-6 encoded by rhesus macaque rhadinovirus is associated with lymphoproliferative disorder (LPD)","volume":"38","author":"Orzechowska","year":"2009","journal-title":"J. Med Primatol."},{"key":"10.1016\/j.virol.2018.04.007_bib66","doi-asserted-by":"crossref","first-page":"4227","DOI":"10.1182\/blood-2008-04-151498","article-title":"Rhesus macaque rhadinovirus-associated non-Hodgkin lymphoma: animal model for KSHV-associated malignancies","volume":"112","author":"Orzechowska","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.virol.2018.04.007_bib67","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1056\/NEJM200011093431904","article-title":"Mucosal shedding of human herpesvirus 8 in men","volume":"343","author":"Pauk","year":"2000","journal-title":"N. Engl. J. Med"},{"key":"10.1016\/j.virol.2018.04.007_bib68","first-page":"421","article-title":"Infection of intestinal epithelial cells and development of systemic disease following gastric instillation of murine gammaherpesvirus-68","volume":"81","author":"Peacock","year":"2000","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib69","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00909-17","article-title":"Human Herpesvirus 8 Infects and Replicates in Langerhans Cells and Interstitial Dermal Dendritic Cells and Impairs Their Function","volume":"91","author":"Rappocciolo","year":"2017","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib70","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.4049\/jimmunol.176.3.1741","article-title":"DC-SIGN is a receptor for human herpesvirus 8 on dendritic cells and macrophages","volume":"176","author":"Rappocciolo","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.virol.2018.04.007_bib71","doi-asserted-by":"crossref","first-page":"3825","DOI":"10.1182\/blood.V91.10.3825","article-title":"Demonstration of Kaposi's sarcoma-associated herpes virus cyclin D homolog in cutaneous Kaposi's sarcoma by colorimetric in situ hybridization using a catalyzed signal amplification system","volume":"91","author":"Reed","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.virol.2018.04.007_bib72","doi-asserted-by":"crossref","first-page":"5182","DOI":"10.1128\/JVI.72.6.5182-5188.1998","article-title":"Limited transmission of Kaposi's sarcoma-associated herpesvirus in cultured cells","volume":"72","author":"Renne","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib73","doi-asserted-by":"crossref","first-page":"5084","DOI":"10.1128\/JVI.77.9.5084-5097.2003","article-title":"Analysis of 4.3 Kb of the divergent locus-B of macaque retroperitoneal fibromatosis-associated herpesvirus (RFHV) reveals close similiarity to Kaposi's sarcoma-associated herpesvirus (KSHV) in gene sequence and genome organization","volume":"77","author":"Rose","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib74","doi-asserted-by":"crossref","first-page":"4138","DOI":"10.1128\/jvi.71.5.4138-4144.1997","article-title":"Identification of two homologs of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in retroperitoneal fibromatosis of different macaque species","volume":"71","author":"Rose","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib75","doi-asserted-by":"crossref","first-page":"14862","DOI":"10.1073\/pnas.93.25.14862","article-title":"Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)","volume":"93","author":"Russo","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.virol.2018.04.007_bib76","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1128\/CVI.00673-12","article-title":"Development of whole-virus multiplex luminex-based serological assays for diagnosis of infections with kaposi's sarcoma-associated herpesvirus\/human herpesvirus 8 homologs in macaques","volume":"20","author":"Ryan","year":"2013","journal-title":"Clin. Vaccin. Immunol."},{"key":"10.1016\/j.virol.2018.04.007_bib77","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/nm0795-707","article-title":"A role for a new herpes virus (KSHV) in different forms of Kaposi's sarcoma","volume":"1","author":"Schalling","year":"1995","journal-title":"Nat. Med"},{"key":"10.1016\/j.virol.2018.04.007_bib78","doi-asserted-by":"crossref","first-page":"4919","DOI":"10.1128\/jvi.74.10.4919-4928.2000","article-title":"Characterization of two divergent lineages of macaque rhadinoviruses related to Kaposi's sarcoma-associated herpesvirus","volume":"74","author":"Schultz","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib79","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.coviro.2015.08.016","article-title":"Kaposi Sarcoma-associated Herpesvirus: mechanisms of oncogenesis","volume":"14","author":"Schulz","year":"2015","journal-title":"Curr. Opin. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib80","doi-asserted-by":"crossref","first-page":"3040","DOI":"10.1128\/JVI.73.4.3040-3053.1999","article-title":"Sequence and genomic analysis of a rhesus macaque rhadinovirus with similarity to Kaposi's sarcoma-associated herpesvirus\/human herpesvirus 8","volume":"73","author":"Searles","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib81","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.virol.2010.10.023","article-title":"The lytic activation of KSHV during keratinocyte differentiation is dependent upon a suprabasal position, the loss of integrin engagement, and calcium, but not the interaction of cadherins","volume":"410","author":"Seifi","year":"2011","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib82","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.virol.2010.01.030","article-title":"Glycoprotein gene sequence variation in rhesus monkey rhadinovirus","volume":"400","author":"Shin","year":"2010","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib83","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/j.1349-7006.1998.tb00557.x","article-title":"Establishment of Epstein-Barr virus-positive human gastric epithelial cell lines","volume":"89","author":"Tajima","year":"1998","journal-title":"Jpn J. Cancer Res"},{"key":"10.1016\/j.virol.2018.04.007_bib84","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1006\/viro.1998.9231","article-title":"Productive infection of Epstein-Barr virus (EBV) in EBV-genome-positive epithelial cell lines (GT38 and GT39) derived from gastric tissues","volume":"247","author":"Takasaka","year":"1998","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib85","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1182\/blood.V89.5.1686","article-title":"Is Kaposi's sarcoma--associated herpesvirus ubiquitous in urogenital and prostate tissues?","volume":"89","author":"Tasaka","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.virol.2018.04.007_bib86","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1128\/JVI.03061-12","article-title":"Complex alternative cytoplasmic protein isoforms of the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 generated through noncanonical translation initiation","volume":"87","author":"Toptan","year":"2013","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib87","doi-asserted-by":"crossref","first-page":"7249","DOI":"10.1128\/JVI.02754-06","article-title":"Epstein-Barr virus infection of Langerhans cell precursors as a mechanism of oral epithelial entry, persistence, and reactivation","volume":"81","author":"Walling","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2018.04.007_bib88","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1177\/154407370601900118","article-title":"Oral EBV and KSHV infection in HIV","volume":"19","author":"Webster-Cyriaque","year":"2006","journal-title":"Adv. Dent. Res"},{"key":"10.1016\/j.virol.2018.04.007_bib89","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1006\/viro.1996.8352","article-title":"Epstein-Barr virus (EBV) infection in salivary gland tumors: lytic EBV infection in nonmalignant epithelial cells surrounded by EBV-positive T-lymphoma cells","volume":"227","author":"Wen","year":"1997","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib90","first-page":"1511","article-title":"Association of Epstein-Barr virus (EBV) with Sjogren's syndrome: differential EBV expression between epithelial cells and lymphocytes in salivary glands","volume":"149","author":"Wen","year":"1996","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.virol.2018.04.007_bib91","first-page":"383","article-title":"Prevalence of viremia and oral shedding of rhesus rhadinovirus and retroperitoneal fibromatosis herpesvirus in large age-structured breeding groups of rhesus macaques (Macaca mulatta)","volume":"59","author":"White","year":"2009","journal-title":"Comp. Med"},{"key":"10.1016\/j.virol.2018.04.007_bib92","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.virol.2006.01.043","article-title":"Immunization with HIV-1 SF162-derived Envelope gp140 proteins does not protect macaques from heterologous simian-human immunodeficiency virus SHIV89.6P infection","volume":"349","author":"Xu","year":"2006","journal-title":"Virology"},{"key":"10.1016\/j.virol.2018.04.007_bib93","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/S0003-9969(97)00049-6","article-title":"Detection of human herpesvirus 7 in salivary glands","volume":"42","author":"Yadav","year":"1997","journal-title":"Arch. Oral. Biol."},{"key":"10.1016\/j.virol.2018.04.007_bib94","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/(SICI)1096-9896(199711)183:3<293::AID-PATH937>3.0.CO;2-C","article-title":"Epstein-Barr virus infection in non-carcinomatous gastric epithelium","volume":"183","author":"Yanai","year":"1997","journal-title":"J. Pathol."},{"key":"10.1016\/j.virol.2018.04.007_bib95","first-page":"E1034","article-title":"Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS","volume":"113","author":"Zhang","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.virol.2018.04.007_bib96","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.bbrc.2010.05.147","article-title":"Kaposi's sarcoma-associated herpesvirus processivity factor-8 dimerizes in cytoplasm before being translocated to nucleus","volume":"397","author":"Zhou","year":"2010","journal-title":"Biochem Biophys. Res Commun."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682218301181?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682218301181?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:44:50Z","timestamp":1758588290000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682218301181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":96,"alternative-id":["S0042682218301181"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2018.04.007","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Macaque homologs of Kaposi's sarcoma-associated herpesvirus (KSHV) infect germinal center lymphoid cells, epithelial cells in skin and gastrointestinal tract and gonadal germ cells in naturally infected macaques","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2018.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}