{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:55:32Z","timestamp":1792169732051,"version":"4.4.0"},"reference-count":86,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01HD090065"],"award-info":[{"award-number":["R01HD090065"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI098984"],"award-info":[{"award-number":["R01AI098984"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI100933"],"award-info":[{"award-number":["R01AI100933"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008333","name":"University of Alabama at Birmingham","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008333","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.virol.2020.05.012","type":"journal-article","created":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T08:05:38Z","timestamp":1591862738000},"page":"236-249","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Guinea pig cytomegalovirus trimer complex gH\/gL\/gO uses PDGFRA as universal receptor for cell fusion and entry"],"prefix":"10.1016","volume":"548","author":[{"given":"Nadia S.","family":"El-Hamdi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Yeon","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alistair","family":"McGregor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virol.2020.05.012_bib1","series-title":"Seminars in Perinatology","first-page":"10","article-title":"Recent advances in the prevention and treatment of congenital cytomegalovirus infections","author":"Adler","year":"2007"},{"key":"10.1016\/j.virol.2020.05.012_bib2","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.coviro.2014.06.004","article-title":"Influenza virus\u2013glycan interactions","volume":"7","author":"Air","year":"2014","journal-title":"Curr. Opin. Virol."},{"issue":"7","key":"10.1016\/j.virol.2020.05.012_bib3","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1093\/glycob\/cwy021","article-title":"Global aspects of viral glycosylation","volume":"28","author":"Bagdonaite","year":"2018","journal-title":"Glycobiology"},{"key":"10.1016\/j.virol.2020.05.012_bib4","article-title":"DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-1\/2 that promotes efficient DNA repair","volume":"4","author":"Belin","year":"2015","journal-title":"Elife"},{"issue":"2","key":"10.1016\/j.virol.2020.05.012_bib5","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.virol.2004.03.039","article-title":"Influence of N-linked glycans on intracellular transport of hepatitis C virus E1 chimeric glycoprotein and its role in pseudotype virus infectivity","volume":"324","author":"Beyene","year":"2004","journal-title":"Virology"},{"issue":"1","key":"10.1016\/j.virol.2020.05.012_bib6","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1093\/infdis\/171.1.182","article-title":"Virus-specific antibody responses to human cytomegalovirus (HCMV) in human immunodeficiency virus type 1-infected persons with HCMV retinitis","volume":"171","author":"Boppana","year":"1995","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2020.05.012_bib7","series-title":"Congenital cytomegalovirus infection: clinical outcome. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America","first-page":"S178","author":"Boppana","year":"2013"},{"issue":"9","key":"10.1016\/j.virol.2020.05.012_bib8","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1002\/jmv.21241","article-title":"Genotypic analysis of two hypervariable human cytomegalovirus genes","volume":"80","author":"Bradley","year":"2008","journal-title":"J. Med. Virol."},{"issue":"2","key":"10.1016\/j.virol.2020.05.012_bib9","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1006\/viro.1994.1294","article-title":"Identification of an abundant disulfide-linked complex of glycoproteins in the envelope of Guinea pig cytomegalovirus","volume":"201","author":"Britt","year":"1994","journal-title":"Virology"},{"issue":"5\u20136","key":"10.1016\/j.virol.2020.05.012_bib10","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1159\/000150510","article-title":"Human cytomegalovirus glycoproteins","volume":"39","author":"Britt","year":"1996","journal-title":"Intervirology"},{"issue":"5","key":"10.1016\/j.virol.2020.05.012_bib11","first-page":"12","article-title":"Opposing regulation of the EGF receptor: a molecular switch controlling cytomegalovirus latency and replication","author":"Buehler","year":"2016","journal-title":"PLoS Pathog."},{"issue":"52","key":"10.1016\/j.virol.2020.05.012_bib12","doi-asserted-by":"crossref","first-page":"22369","DOI":"10.1073\/pnas.0908787106","article-title":"Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility","volume":"106","author":"Chan","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"10","key":"10.1016\/j.virol.2020.05.012_bib16","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.1016\/j.vaccine.2020.01.063","article-title":"Neutralizing antibodies to gB based CMV vaccine requires full length antigen but reduced virus neutralization on non-fibroblast cells limits vaccine efficacy in the Guinea pig model","volume":"38","author":"Choi","year":"2020","journal-title":"Vaccine"},{"issue":"17","key":"10.1016\/j.virol.2020.05.012_bib13","doi-asserted-by":"crossref","first-page":"7902","DOI":"10.1128\/JVI.00283-16","article-title":"A novel non-replication-competent cytomegalovirus capsid mutant vaccine strategy is Effective in reducing congenital infection","volume":"90","author":"Choi","year":"2016","journal-title":"J. Virol."},{"issue":"22","key":"10.1016\/j.virol.2020.05.012_bib14","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.01442-19","article-title":"Inclusion of the viral pentamer complex in a vaccine design greatly improves protection against congenital cytomegalovirus in the Guinea pig model","volume":"93","author":"Choi","year":"2019","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.virol.2020.05.012_bib15","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1099\/jgv.0.001394","article-title":"Requirements for Guinea pig cytomegalovirus tropism and antibody neutralization on placental amniotic sac cells","volume":"101","author":"Choi","year":"2020","journal-title":"J. Generl. Virol."},{"issue":"52","key":"10.1016\/j.virol.2020.05.012_bib17","doi-asserted-by":"crossref","first-page":"18153","DOI":"10.1073\/pnas.0405172102","article-title":"Influenza virus entry and infection require host cell N-linked glycoprotein","volume":"101","author":"Chu","year":"2004","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"issue":"6","key":"10.1016\/j.virol.2020.05.012_bib18","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1073\/pnas.1424818112","article-title":"Structural and biochemical studies of HCMV gH\/gL\/gO and Pentamer reveal mutually exclusive cell entry complexes","volume":"112","author":"Ciferri","year":"2015","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"key":"10.1016\/j.virol.2020.05.012_bib22","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.virol.2017.06.008","article-title":"Cytomegalovirus UL128 homolog mutants that form a pentameric complex produce virus with impaired epithelial and trophoblast cell tropism and altered pathogenicity in the Guinea pig","volume":"509","author":"Coleman","year":"2017","journal-title":"Virology"},{"issue":"7","key":"10.1016\/j.virol.2020.05.012_bib20","first-page":"12","article-title":"A homolog pentameric complex dictates viral epithelial tropism, pathogenicity and congenital infection rate in Guinea pig cytomegalovirus","author":"Coleman","year":"2016","journal-title":"PLoS pathogens"},{"issue":"8","key":"10.1016\/j.virol.2020.05.012_bib19","first-page":"10","article-title":"Viral glycoprotein complex formation, essential function and immunogenicity in the Guinea pig model for cytomegalovirus","author":"Coleman","year":"2015","journal-title":"PloS One"},{"issue":"24","key":"10.1016\/j.virol.2020.05.012_bib23","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00622-17","volume":"91","author":"Collins-McMillen","year":"2017","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virol.2020.05.012_bib24","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/0042-6822(92)90200-9","article-title":"Human cytomegalovirus penetrates host cells by pH-independent fusion at the cell surface","volume":"191","author":"Compton","year":"1992","journal-title":"Virology"},{"issue":"1","key":"10.1016\/j.virol.2020.05.012_bib25","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1038\/s41598-018-19451-6","article-title":"Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma","volume":"8","author":"Connolly","year":"2018","journal-title":"Sci. Rep."},{"issue":"43","key":"10.1016\/j.virol.2020.05.012_bib27","doi-asserted-by":"crossref","first-page":"15470","DOI":"10.1073\/pnas.0406821101","article-title":"Cellular integrins function as entry receptors for human cytomegalovirus via a highly conserved disintegrin-like domain","volume":"101","author":"Feire","year":"2004","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"issue":"Pt 6","key":"10.1016\/j.virol.2020.05.012_bib26","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1099\/vir.0.018994-0","article-title":"Sequential mutations associated with adaptation of human cytomegalovirus to growth in cell culture","volume":"91","author":"Dargan","year":"2010","journal-title":"J. Generl. Virol."},{"issue":"19","key":"10.1016\/j.virol.2020.05.012_bib28","doi-asserted-by":"crossref","first-page":"10026","DOI":"10.1128\/JVI.00710-10","article-title":"The glycoprotein B disintegrin-like domain binds beta 1 integrin to mediate cytomegalovirus entry","volume":"84","author":"Feire","year":"2010","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.virol.2020.05.012_bib29","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1007\/s11481-013-9479-z","article-title":"The roles of PDGF in development and during neurogenesis in the normal and diseased nervous system. Journal of neuroimmune pharmacology","volume":"9","author":"Funa","year":"2014","journal-title":"Offc. J. Soc. Neuroimm. Pharamcol."},{"issue":"3","key":"10.1016\/j.virol.2020.05.012_bib30","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1128\/MMBR.00018-16","article-title":"Virion glycoprotein-mediated immune evasion by human cytomegalovirus: a sticky virus makes a slick getaway","volume":"80","author":"Gardner","year":"2016","journal-title":"Microbiol. Mol. Biol. Rev."},{"issue":"6","key":"10.1016\/j.virol.2020.05.012_bib33","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1093\/infdis\/141.6.787","article-title":"Cytomegalovirus infection in Guinea pigs: IV. Maternal infection at different stages of gestation","volume":"141","author":"Griffith","year":"1980","journal-title":"J. Infect. Dis."},{"issue":"6","key":"10.1016\/j.virol.2020.05.012_bib31","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1128\/jvi.62.6.1956-1962.1988","article-title":"A multigene family encodes the human cytomegalovirus glycoprotein complex gcII (gp47-52 complex)","volume":"62","author":"Gretch","year":"1988","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.virol.2020.05.012_bib32","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1128\/jvi.62.3.875-881.1988","article-title":"Identification and characterization of three distinct families of glycoprotein complexes in the envelopes of human cytomegalovirus","volume":"62","author":"Gretch","year":"1988","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.virol.2020.05.012_bib34","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1128\/jvi.55.2.402-409.1985","article-title":"The placenta as a site of cytomegalovirus infection in Guinea pigs","volume":"55","author":"Griffith","year":"1985","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2020.05.012_bib35","series-title":"New Trends in Cancer for the 21st Century","first-page":"235","article-title":"Development of the epidermal growth factor receptor inhibitor Tarceva\u2122(OSI-774)","author":"Gr\u00fcnwald","year":"2003"},{"issue":"21","key":"10.1016\/j.virol.2020.05.012_bib36","doi-asserted-by":"crossref","first-page":"10708","DOI":"10.1128\/JVI.76.21.10708-10716.2002","article-title":"The transmembrane domain and cytoplasmic tail of herpes simplex virus type 1 glycoprotein H play a role in membrane fusion","volume":"76","author":"Harman","year":"2002","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.virol.2020.05.012_bib37","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/tra.12355","article-title":"HCMV induces macropinocytosis for host cell entry in fibroblasts","volume":"17","author":"Hetzenecker","year":"2016","journal-title":"Traffic"},{"key":"10.1016\/j.virol.2020.05.012_bib38","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.virol.2017.01.023","article-title":"The essential role of Guinea pig cytomegalovirus (GPCMV) IE1 and IE2 homologs in viral replication and IE1-mediated ND10 targeting","volume":"504","author":"Hornig","year":"2017","journal-title":"Virology"},{"issue":"12","key":"10.1016\/j.virol.2020.05.012_bib39","doi-asserted-by":"crossref","first-page":"4701","DOI":"10.1021\/jm100395q","volume":"53","author":"Huang","year":"2010","journal-title":"J. Med. Chem."},{"issue":"10","key":"10.1016\/j.virol.2020.05.012_bib40","doi-asserted-by":"crossref","first-page":"8191","DOI":"10.1128\/JVI.72.10.8191-8197.1998","article-title":"The human cytomegalovirus UL74 gene encodes the third component of the glycoprotein H-glycoprotein L-containing envelope complex","volume":"72","author":"Huber","year":"1998","journal-title":"J. Virol."},{"issue":"8","key":"10.1016\/j.virol.2020.05.012_bib41","doi-asserted-by":"crossref","first-page":"3891","DOI":"10.1128\/JVI.01251-08","article-title":"Human cytomegalovirus glycoprotein B is required for virus entry and cell-to-cell spread but not for virion attachment, assembly, or egress","volume":"83","author":"Isaacson","year":"2009","journal-title":"J. Virol."},{"issue":"12","key":"10.1016\/j.virol.2020.05.012_bib42","doi-asserted-by":"crossref","first-page":"6241","DOI":"10.1128\/JVI.00169-07","article-title":"Epidermal growth factor receptor is not required for human cytomegalovirus entry or signaling","volume":"81","author":"Isaacson","year":"2007","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.virol.2020.05.012_bib43","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/infdis\/120.4.445","article-title":"Mouse cytomegalovirus: placental infection","volume":"120","author":"Johnson","year":"1969","journal-title":"J. Infect. Dis."},{"issue":"8","key":"10.1016\/j.virol.2020.05.012_bib44","doi-asserted-by":"crossref","first-page":"16082","DOI":"10.1038\/nmicrobiol.2016.82","article-title":"Platelet-derived growth factor-alpha receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer","volume":"1","author":"Kabanova","year":"2016","journal-title":"Nat Microbiol"},{"issue":"5","key":"10.1016\/j.virol.2020.05.012_bib45","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.01206-16","article-title":"Human cytomegalovirus requires epidermal growth factor receptor signaling to enter and initiate the early steps in the establishment of latency in CD34+ human progenitor cells","volume":"91","author":"Kim","year":"2017","journal-title":"J. Virol."},{"issue":"19","key":"10.1016\/j.virol.2020.05.012_bib46","doi-asserted-by":"crossref","first-page":"9444","DOI":"10.1128\/JVI.00572-06","article-title":"Soluble Epstein-Barr virus glycoproteins gH, gL, and gp42 form a 1: 1: 1 stable complex that acts like soluble gp42 in B-cell fusion but not in epithelial cell fusion","volume":"80","author":"Kirschner","year":"2006","journal-title":"J. Virol."},{"issue":"19","key":"10.1016\/j.virol.2020.05.012_bib47","doi-asserted-by":"crossref","first-page":"10316","DOI":"10.1128\/JVI.00375-07","article-title":"The cytoplasmic tail of glycoprotein M (gpUL100) expresses trafficking signals required for human cytomegalovirus assembly and replication","volume":"81","author":"Krzyzaniak","year":"2007","journal-title":"J. Virol."},{"issue":"5","key":"10.1016\/j.virol.2020.05.012_bib48","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1093\/infdis\/138.5.650","article-title":"Experimental congenital infection with cytomegalovirus: a Guinea pig model","volume":"138","author":"Kumar","year":"1978","journal-title":"J. Infect. Dis."},{"issue":"14","key":"10.1016\/j.virol.2020.05.012_bib49","doi-asserted-by":"crossref","first-page":"4471","DOI":"10.1073\/pnas.1419875112","article-title":"A viral regulator of glycoprotein complexes contributes to human cytomegalovirus cell tropism","volume":"112","author":"Li","year":"2015","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"issue":"10","key":"10.1016\/j.virol.2020.05.012_bib50","doi-asserted-by":"crossref","first-page":"5212","DOI":"10.1128\/JVI.01463-06","article-title":"The carboxy-terminal domain of glycoprotein N of human cytomegalovirus is required for virion morphogenesis","volume":"81","author":"Mach","year":"2007","journal-title":"J. Virol."},{"issue":"5","key":"10.1016\/j.virol.2020.05.012_bib51","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/j.cell.2018.06.028","article-title":"An unbiased screen for human cytomegalovirus identifies neuropilin-2 as a central viral receptor","volume":"174","author":"Martinez-Martin","year":"2018","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.virol.2020.05.012_bib52","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1006\/mgme.2000.3102","article-title":"Molecular cloning of the Guinea pig cytomegalovirus (GPCMV) genome as an infectious bacterial artificial chromosome (BAC) in Escherichia coli","volume":"72","author":"McGregor","year":"2001","journal-title":"Mol. Genet. Metabol."},{"issue":"18","key":"10.1016\/j.virol.2020.05.012_bib53","doi-asserted-by":"crossref","first-page":"9872","DOI":"10.1128\/JVI.78.18.9872-9889.2004","article-title":"Molecular, biological, and in vivo characterization of the Guinea pig cytomegalovirus (CMV) homologs of the human CMV matrix proteins pp71 (UL82) and pp65 (UL83)","volume":"78","author":"McGregor","year":"2004","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virol.2020.05.012_bib54","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.virol.2010.10.028","article-title":"Guinea pig cytomegalovirus GP84 is a functional homolog of the human cytomegalovirus (HCMV) UL84 gene that can complement for the loss of UL84 in a chimeric HCMV","volume":"410","author":"McGregor","year":"2011","journal-title":"Virology"},{"issue":"19","key":"10.1016\/j.virol.2020.05.012_bib55","doi-asserted-by":"crossref","first-page":"10489","DOI":"10.1128\/JVI.01546-13","article-title":"Impact of sequence variation in the UL128 locus on production of human cytomegalovirus in fibroblast and epithelial cells","volume":"87","author":"Murrell","year":"2013","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virol.2020.05.012_bib87","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1038\/s41598-020-57471-3","article-title":"Differential Expression of PDGF receptor-\u03b1 in human placental trophoblasts Leads to different entry Pathways by human cytomegalovirus strains","volume":"10","author":"Naing","year":"2020","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.virol.2020.05.012_bib56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41541-018-0074-4","article-title":"A new era in cytomegalovirus vaccinology: considerations for rational design of next-generation vaccines to prevent congenital cytomegalovirus infection","volume":"3","author":"Nelson","year":"2018","journal-title":"NPJ Vaccines"},{"issue":"18","key":"10.1016\/j.virol.2020.05.012_bib57","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00688-18","article-title":"Human cytomegalovirus tropism modulator UL148 interacts with SEL1L, a cellular factor that governs endoplasmic reticulum-associated degradation of the viral envelope glycoprotein gO","volume":"92","author":"Nguyen","year":"2018","journal-title":"J. Virol."},{"issue":"5","key":"10.1016\/j.virol.2020.05.012_bib58","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.ccr.2009.09.028","article-title":"AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance","volume":"16","author":"Zhou","year":"2009","journal-title":"Canc. Cell"},{"issue":"12","key":"10.1016\/j.virol.2020.05.012_bib59","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1056\/NEJMoa0804749","article-title":"Vaccine prevention of maternal cytomegalovirus infection","volume":"360","author":"Pass","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.virol.2020.05.012_bib60","series-title":"Proceedings of the National Academy of Sciences of the United States of America","article-title":"Limits and patterns of cytomegalovirus genomic diversity in humans","volume":"112","author":"Renzette","year":"2015"},{"issue":"3","key":"10.1016\/j.virol.2020.05.012_bib61","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/rmv.645","article-title":"Human cytomegalovirus tropism for endothelial\/epithelial cells: scientific background and clinical implications","volume":"20","author":"Revello","year":"2010","journal-title":"Rev. Med. Virol."},{"issue":"2","key":"10.1016\/j.virol.2020.05.012_bib62","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1128\/JVI.80.2.710-722.2006","article-title":"Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion","volume":"80","author":"Ryckman","year":"2006","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.virol.2020.05.012_bib63","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0092-8674(00)00114-8","article-title":"Cell signaling by receptor tyrosine kinases","volume":"103","author":"Schlessinger","year":"2000","journal-title":"Cell"},{"issue":"17","key":"10.1016\/j.virol.2020.05.012_bib64","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1016\/j.vaccine.2007.01.011","article-title":"DNA vaccines expressing glycoprotein complex II antigens gM and gN elicited neutralizing antibodies against multiple human cytomegalovirus (HCMV) isolates","volume":"25","author":"Shen","year":"2007","journal-title":"Vaccine"},{"issue":"9","key":"10.1016\/j.virol.2020.05.012_bib65","doi-asserted-by":"crossref","first-page":"4591","DOI":"10.1128\/JVI.80.9.4591-4600.2006","article-title":"Human cytomegalovirus infection elicits a glycoprotein M (gM)\/gN-specific virus-neutralizing antibody response","volume":"80","author":"Shimamura","year":"2006","journal-title":"J. Virol."},{"issue":"12","key":"10.1016\/j.virol.2020.05.012_bib66","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007452","article-title":"Different functional states of fusion protein gB revealed on human cytomegalovirus by cryo electron tomography with Volta phase plate","volume":"14","author":"Si","year":"2018","journal-title":"PLoS Pathog."},{"issue":"7211","key":"10.1016\/j.virol.2020.05.012_bib67","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/nature07209","article-title":"Platelet-derived growth factor-\u03b1 receptor activation is required for human cytomegalovirus infection","volume":"455","author":"Soroceanu","year":"2008","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.virol.2020.05.012_bib68","first-page":"13","article-title":"A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells","author":"Stegmann","year":"2017","journal-title":"PLoS pathogens"},{"issue":"11","key":"10.1016\/j.virol.2020.05.012_bib69","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00138-19","article-title":"The N Terminus of human cytomegalovirus glycoprotein O is Important for Binding to the cellular receptor PDGFR\u03b1","volume":"93","author":"Stegmann","year":"2019","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virol.2020.05.012_bib70","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1038\/s41467-019-10587-1","article-title":"CD46 facilitates entry and dissemination of human cytomegalovirus","volume":"10","author":"Stein","year":"2019","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.virol.2020.05.012_bib75","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005564","article-title":"Human Cytomegalovirus gH\/gL Forms a stable Complex with the fusion Protein gB in virions","volume":"12","author":"Vanarsdall","year":"2016","journal-title":"PLoS pathog"},{"issue":"1","key":"10.1016\/j.virol.2020.05.012_bib72","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.coviro.2012.01.001","article-title":"Human cytomegalovirus entry into cells","volume":"2","author":"Vanarsdall","year":"2012","journal-title":"Curr. Opin. Virol."},{"issue":"6220","key":"10.1016\/j.virol.2020.05.012_bib71","doi-asserted-by":"crossref","DOI":"10.1126\/science.1260419","article-title":"Tissue-based map of the human proteome","volume":"347","author":"Uhl\u00e9n","year":"2015","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.virol.2020.05.012_bib76","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00781-18","article-title":"CD147 promotes entry of pentamer-expressing human cytomegalovirus into epithelial and endothelial cells","volume":"9","author":"Vanarsdall","year":"2018","journal-title":"mBio"},{"issue":"23","key":"10.1016\/j.virol.2020.05.012_bib73","doi-asserted-by":"crossref","first-page":"11837","DOI":"10.1128\/JVI.01623-08","article-title":"Human cytomegalovirus glycoproteins gB and gH\/gL mediate epithelial cell-cell fusion when expressed either in cis or in trans","volume":"82","author":"Vanarsdall","year":"2008","journal-title":"J. Virol."},{"issue":"9","key":"10.1016\/j.virol.2020.05.012_bib74","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002905","article-title":"PDGF receptor-\u03b1 does not promote HCMV entry into epithelial and endothelial cells but increased quantities stimulate entry by an abnormal pathway","volume":"8","author":"Vanarsdall","year":"2012","journal-title":"PLoS pathogens"},{"issue":"6947","key":"10.1016\/j.virol.2020.05.012_bib77","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/nature01818","article-title":"Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus","volume":"424","author":"Wang","year":"2003","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.virol.2020.05.012_bib78","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/nm1236","article-title":"Integrin \u03b1v\u03b23 is a coreceptor for human cytomegalovirus","volume":"11","author":"Wang","year":"2005","journal-title":"Nat. Med."},{"issue":"3","key":"10.1016\/j.virol.2020.05.012_bib79","first-page":"4","article-title":"Human cytomegalovirus (HCMV) glycoprotein gB promotes virus entry in trans acting as the viral fusion protein rather than as a receptor-binding protein","author":"Wille","year":"2013","journal-title":"mBio"},{"issue":"3 Suppl. 3","key":"10.1016\/j.virol.2020.05.012_bib80","first-page":"32","article-title":"Guinea pig model of congenital CMV-induced hearing loss: a review","volume":"23","author":"Woolf","year":"1991","journal-title":"Transplant. Proc."},{"issue":"4","key":"10.1016\/j.virol.2020.05.012_bib81","first-page":"13","article-title":"Human cytomegalovirus glycoprotein complex gH\/gL\/gO uses PDGFR-alpha as a key for entry","author":"Wu","year":"2017","journal-title":"PLoS Pathog."},{"issue":"42","key":"10.1016\/j.virol.2020.05.012_bib82","first-page":"115","article-title":"Role of PDGF receptor-alpha during human cytomegalovirus entry into fibroblasts","author":"Wu","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"14","key":"10.1016\/j.virol.2020.05.012_bib83","doi-asserted-by":"crossref","first-page":"7043","DOI":"10.1073\/pnas.1814850116","article-title":"OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism","volume":"116","author":"Xiaofei","year":"2019","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"issue":"Pt 6","key":"10.1016\/j.virol.2020.05.012_bib84","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1099\/vir.0.064527-0","article-title":"Guinea pig cytomegalovirus GP129\/131\/133, homologues of human cytomegalovirus UL128\/130\/131A, are necessary for infection of monocytes and macrophages","volume":"95","author":"Yamada","year":"2014","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2020.05.012_bib85","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2019.103776","article-title":"Blocking cellular N-glycosylation suppresses human cytomegalovirus entry in human fibroblasts","volume":"138","author":"Zheng","year":"2020","journal-title":"Microb. Pathog."},{"issue":"17","key":"10.1016\/j.virol.2020.05.012_bib86","doi-asserted-by":"crossref","first-page":"8999","DOI":"10.1128\/JVI.01325-15","article-title":"Human cytomegalovirus gH\/gL\/gO promotes the fusion step of entry into all cell types, whereas gH\/gL\/UL128-131 broadens virus tropism through a distinct mechanism","volume":"89","author":"Zhou","year":"2015","journal-title":"J. Virol."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682220300982?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682220300982?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:39:19Z","timestamp":1792168759000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682220300982"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":86,"alternative-id":["S0042682220300982"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2020.05.012","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Guinea pig cytomegalovirus trimer complex gH\/gL\/gO uses PDGFRA as universal receptor for cell fusion and entry","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2020.05.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}