{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T23:48:22Z","timestamp":1789775302857,"version":"4.0.1"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T00:00:00Z","timestamp":1621900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R21AI142504"],"award-info":[{"award-number":["R21AI142504"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.virol.2021.05.001","type":"journal-article","created":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T08:02:30Z","timestamp":1620979350000},"page":"43-53","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Persistence of Zika virus RNA in the epididymis of the murine male reproductive tract"],"prefix":"10.1016","volume":"560","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4520-3077","authenticated-orcid":false,"given":"Megan B.","family":"Vogt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Frere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seth A.","family":"Hawks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0186-843X","authenticated-orcid":false,"given":"Claudia E.","family":"Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7385-3969","authenticated-orcid":false,"given":"Sheryl","family":"Coutermarsh-Ott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9893-8069","authenticated-orcid":false,"given":"Nisha K.","family":"Duggal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virol.2021.05.001_bib1","article-title":"Characterization of lethal Zika virus infection in AG129 mice","volume":"10","author":"Aliota","year":"2016","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib2","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0010649","article-title":"Persistence of West Nile virus in the central nervous system and periphery of mice","volume":"5","author":"Appler","year":"2010","journal-title":"PloS One"},{"key":"10.1016\/j.virol.2021.05.001_bib3","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1093\/cid\/cix967","article-title":"Virus and antibody dynamics in travelers with acute Zika virus infection","volume":"66","author":"Barzon","year":"2018","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib4","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1093\/infdis\/jis221","article-title":"Evaluation for West Nile virus (WNV) RNA in urine of patients within 5 months of WNV infection","volume":"205","author":"Baty","year":"2012","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib5","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.ajpath.2017.12.019","article-title":"Comparative histopathologic lesions of the male reproductive tract during acute infection of Zika virus in AG129 and ifnar(-\/-) mice","volume":"188","author":"Clancy","year":"2018","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.virol.2021.05.001_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1002611","article-title":"Sexual transmission of Zika virus and other flaviviruses: a living systematic review","volume":"15","author":"Counotte","year":"2018","journal-title":"PLoS Med."},{"key":"10.1016\/j.virol.2021.05.001_bib7","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.mce.2010.04.005","article-title":"The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights","volume":"335","author":"Coutinho","year":"2011","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.virol.2021.05.001_bib8","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1056\/NEJMc1604449","article-title":"Evidence of sexual transmission of Zika virus","volume":"374","author":"D'Ortenzio","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.virol.2021.05.001_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004658","article-title":"A susceptible mouse model for Zika virus infection","volume":"10","author":"Dowall","year":"2016","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib10","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1016\/j.celrep.2017.01.056","article-title":"Frequent Zika virus sexual transmission and prolonged viral RNA shedding in an immunodeficient mouse model","volume":"18","author":"Duggal","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.virol.2021.05.001_bib11","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.4269\/ajtmh.17-0263","article-title":"Differential neurovirulence of african and asian genotype Zika virus isolates in outbred immunocompetent mice","volume":"97","author":"Duggal","year":"2017","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.virol.2021.05.001_bib12","doi-asserted-by":"crossref","first-page":"4510","DOI":"10.1038\/s41598-018-22840-6","article-title":"Sexual transmission of Zika virus enhances in utero transmission in a mouse model","volume":"8","author":"Duggal","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2021.05.001_bib13","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1093\/cid\/ciy261","article-title":"Duration of Zika viremia in serum","volume":"67","author":"Fontaine","year":"2018","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib14","doi-asserted-by":"crossref","first-page":"880","DOI":"10.3201\/eid1705.101939","article-title":"Probable non-vector-borne transmission of Zika virus, Colorado, USA","volume":"17","author":"Foy","year":"2011","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib15","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2016.21.23.30254","article-title":"Sexual transmission of Zika virus in an entirely asymptomatic couple returning from a Zika epidemic area, France","volume":"21","author":"Freour","year":"2016","journal-title":"Euro Surveill."},{"key":"10.1016\/j.virol.2021.05.001_bib16","article-title":"Prevention and control of Zika as a mosquito-borne and sexually transmitted disease: a mathematical modeling analysis","volume":"6","author":"Gao","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2021.05.001_bib17","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s40425-018-0371-5","article-title":"Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy","volume":"6","author":"Giles","year":"2018","journal-title":"J Immunother Cancer"},{"key":"10.1016\/j.virol.2021.05.001_bib18","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1038\/nature20556","article-title":"Zika virus infection damages the testes in mice","volume":"540","author":"Govero","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.virol.2021.05.001_bib19","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1128\/JVI.77.1.25-36.2003","article-title":"Characterization of a siberian virus isolated from a patient with progressive chronic tick-borne encephalitis","volume":"77","author":"Gritsun","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2021.05.001_bib20","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1093\/infdis\/jiz533","article-title":"Zika virus causes acute and chronic prostatitis in mice and macaques","volume":"221","author":"Halabi","year":"2020","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib21","doi-asserted-by":"crossref","first-page":"5957","DOI":"10.1128\/JVI.74.13.5957-5967.2000","article-title":"Optimized viral dose and transient immunosuppression enable herpes simplex virus ICP0-null mutants to establish wild-type levels of latency in vivo","volume":"74","author":"Halford","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2021.05.001_bib22","doi-asserted-by":"crossref","first-page":"215","DOI":"10.15585\/mmwr.mm6508e2","article-title":"Transmission of Zika virus through sexual contact with travelers to areas of ongoing transmission - continental United States, 2016","volume":"65","author":"Hills","year":"2016","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.virol.2021.05.001_bib23","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1001\/jama.2016.19006","article-title":"Birth defects among fetuses and infants of US women with evidence of possible Zika virus infection during pregnancy","volume":"317","author":"Honein","year":"2017","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.virol.2021.05.001_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008509","article-title":"Matrix metalloproteinase 9 facilitates Zika virus invasion of the testis by modulating the integrity of the blood-testis barrier","volume":"16","author":"Hui","year":"2020","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2021.05.001_bib25","first-page":"7177","article-title":"An improved and versatile immunosuppression protocol for the development of tumor xenograft in mice","volume":"34","author":"Jivrajani","year":"2014","journal-title":"Anticancer Res."},{"key":"10.1016\/j.virol.2021.05.001_bib26","doi-asserted-by":"crossref","first-page":"5477","DOI":"10.1038\/s41598-018-23899-x","article-title":"Human Sertoli cells support high levels of Zika virus replication and persistence","volume":"8","author":"Kumar","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2021.05.001_bib27","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.3201\/eid1408.080287","article-title":"Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007","volume":"14","author":"Lanciotti","year":"2008","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib28","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.chom.2016.03.010","article-title":"A mouse model of Zika virus pathogenesis","volume":"19","author":"Lazear","year":"2016","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.virol.2021.05.001_bib29","doi-asserted-by":"crossref","first-page":"152","DOI":"10.3389\/fimmu.2012.00152","article-title":"Structural, cellular and molecular aspects of immune privilege in the testis","volume":"3","author":"Li","year":"2012","journal-title":"Front. Immunol."},{"key":"10.1016\/j.virol.2021.05.001_bib30","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/j.cell.2016.11.016","article-title":"Zika virus causes testis damage and leads to male infertility in mice","volume":"167","author":"Ma","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.virol.2021.05.001_bib31","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/S1473-3099(20)30834-3","article-title":"Long-term Zika virus infection of non-sperm cells in semen","volume":"20","author":"Mahe","year":"2020","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib32","doi-asserted-by":"crossref","first-page":"863","DOI":"10.3201\/eid2305.161631","article-title":"Zika virus infection and prolonged viremia in whole-blood specimens","volume":"23","author":"Mansuy","year":"2017","journal-title":"Emerg. Infect. Dis."},{"issue":"Pt 2","key":"10.1016\/j.virol.2021.05.001_bib33","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1099\/0022-1317-67-2-381","article-title":"Persistence, latency and reactivation of Japanese encephalitis virus infection in mice","volume":"67","author":"Mathur","year":"1986","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2021.05.001_bib34","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0162-3109(00)00192-2","article-title":"Mechanisms of action of cyclosporine","volume":"47","author":"Matsuda","year":"2000","journal-title":"Immunopharmacology"},{"key":"10.1016\/j.virol.2021.05.001_bib35","doi-asserted-by":"crossref","first-page":"4697","DOI":"10.1172\/JCI121735","article-title":"Zika virus infects human testicular tissue and germ cells","volume":"128","author":"Matusali","year":"2018","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.virol.2021.05.001_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0005990","article-title":"Pathogenesis and sexual transmission of Spondweni and Zika viruses","volume":"11","author":"McDonald","year":"2017","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006691","article-title":"Infection of epididymal epithelial cells and leukocytes drives seminal shedding of Zika virus in a mouse model","volume":"12","author":"McDonald","year":"2018","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.virol.2019.06.010","article-title":"Duration of seminal Zika viral RNA shedding in immunocompetent mice inoculated with Asian and African genotype viruses","volume":"535","author":"McDonald","year":"2019","journal-title":"Virology"},{"key":"10.1016\/j.virol.2021.05.001_bib39","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1056\/NEJMoa1711038","article-title":"Zika virus shedding in semen of symptomatic infected men","volume":"378","author":"Mead","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.virol.2021.05.001_bib40","first-page":"31","article-title":"Duration of the presence of infectious Zika virus in semen and serum","volume":"219","author":"Medina","year":"2019","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib41","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.vetpar.2006.04.016","article-title":"Characterization of a single dose methylprednisolone acetate immune suppression model using Cryptosporidium muris and Cryptosporidium parvum","volume":"141","author":"Miller","year":"2006","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.virol.2021.05.001_bib42","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.vetpar.2007.08.017","article-title":"Changes in mouse circulating leukocyte numbers in C57BL\/6 mice immunosuppressed with dexamethasone for Cryptosporidium parvum oocyst production","volume":"149","author":"Miller","year":"2007","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.virol.2021.05.001_bib43","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1095\/biolreprod.110.087452","article-title":"The blood-testis and blood-epididymis barriers are more than just their tight junctions","volume":"84","author":"Mital","year":"2011","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.virol.2021.05.001_bib44","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/2049-632X.12178","article-title":"The role of viral persistence in flavivirus biology","volume":"71","author":"Mlera","year":"2014","journal-title":"Pathog Dis"},{"key":"10.1016\/j.virol.2021.05.001_bib45","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1086\/648731","article-title":"Persistent infection with West Nile virus years after initial infection","volume":"201","author":"Murray","year":"2010","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib46","doi-asserted-by":"crossref","first-page":"359","DOI":"10.3201\/eid2102.141363","article-title":"Potential sexual transmission of Zika virus","volume":"21","author":"Musso","year":"2015","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib47","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.01434-19","article-title":"Zika virus infection, reproductive organ targeting, and semen transmission in the male olive baboon","volume":"94","author":"Peregrine","year":"2019","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2021.05.001_bib48","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.3201\/eid2508.181543","article-title":"Prolonged Zika virus RNA detection in semen of immunosuppressed patient","volume":"25","author":"Petridou","year":"2019","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib49","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/BF01314128","article-title":"Study on West Nile virus persistence in monkeys","volume":"75","author":"Pogodina","year":"1983","journal-title":"Arch. Virol."},{"key":"10.1016\/j.virol.2021.05.001_bib50","doi-asserted-by":"crossref","first-page":"366","DOI":"10.15585\/mmwr.mm6613e1","article-title":"Vital signs: update on Zika virus-associated birth defects and evaluation of all U.S. Infants with congenital Zika virus exposure - U.S. Zika pregnancy registry, 2016","volume":"66","author":"Reynolds","year":"2017","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.virol.2021.05.001_bib51","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.4269\/ajtmh.16-0111","article-title":"Characterization of a novel murine model to study Zika virus","volume":"94","author":"Rossi","year":"2016","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.virol.2021.05.001_bib52","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/0049-0172(92)90009-3","article-title":"Mechanisms of action of cyclosporine and effects on connective tissues","volume":"21","author":"Russell","year":"1992","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.virol.2021.05.001_bib53","doi-asserted-by":"crossref","first-page":"615","DOI":"10.15585\/mmwr.mm6623e1","article-title":"Pregnancy outcomes after maternal Zika virus infection during pregnancy - U.S. Territories, january 1, 2016-april 25, 2017","volume":"66","author":"Shapiro-Mendoza","year":"2017","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.virol.2021.05.001_bib54","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1365-2249.1991.tb05687.x","article-title":"Japanese encephalitis virus latency in peripheral blood lymphocytes and recurrence of infection in children","volume":"85","author":"Sharma","year":"1991","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.virol.2021.05.001_bib55","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1089\/jir.2006.26.804","article-title":"Blocking monoclonal antibodies specific for mouse IFN-alpha\/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection","volume":"26","author":"Sheehan","year":"2006","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.virol.2021.05.001_bib56","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00623-17","article-title":"Zika virus infects human sertoli cells and modulates the integrity of the in vitro blood-testis barrier model","volume":"91","author":"Siemann","year":"2017","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2021.05.001_bib57","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0005296","article-title":"Neuropathogenesis of Zika virus in a highly susceptible immunocompetent mouse model after antibody blockade of type I interferon","volume":"11","author":"Smith","year":"2017","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib58","doi-asserted-by":"crossref","first-page":"67","DOI":"10.15585\/mmwr.mm6903a3","article-title":"Population-based surveillance for birth defects potentially related to Zika virus infection - 22 states and territories, january 2016-june 2017","volume":"69","author":"Smoots","year":"2020","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.virol.2021.05.001_bib59","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1093\/infdis\/jix436","article-title":"Replication of Zika virus in human prostate cells: a potential source of sexually transmitted virus","volume":"217","author":"Spencer","year":"2018","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib60","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006733","article-title":"Estimating the effects of variation in viremia on mosquito susceptibility, infectiousness, and R0 of Zika in Aedes aegypti","volume":"12","author":"Tesla","year":"2018","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.virol.2021.05.001_bib61","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.epidem.2016.10.003","article-title":"Estimate of the reproduction number of the 2015 Zika virus outbreak in Barranquilla, Colombia, and estimation of the relative role of sexual transmission","volume":"17","author":"Towers","year":"2016","journal-title":"Epidemics"},{"key":"10.1016\/j.virol.2021.05.001_bib62","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.1602899","article-title":"Zika virus causes testicular atrophy","volume":"3","author":"Uraki","year":"2017","journal-title":"Sci Adv"},{"key":"10.1016\/j.virol.2021.05.001_bib63","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40738-018-0053-5","article-title":"Congenital Zika syndrome arising from sexual transmission of Zika virus, a case report","volume":"5","author":"Yarrington","year":"2019","journal-title":"Fertil Res Pract"},{"key":"10.1016\/j.virol.2021.05.001_bib64","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1038\/cmi.2014.38","article-title":"Testicular defense systems: immune privilege and innate immunity","volume":"11","author":"Zhao","year":"2014","journal-title":"Cell. Mol. Immunol."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682221001057?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682221001057?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:54:39Z","timestamp":1758588879000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682221001057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":64,"alternative-id":["S0042682221001057"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2021.05.001","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.10.08.330019","asserted-by":"object"}]},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Persistence of Zika virus RNA in the epididymis of the murine male reproductive tract","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2021.05.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}