{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T21:41:53Z","timestamp":1787953313004,"version":"build-2784847793"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.virol.2022.08.013","type":"journal-article","created":{"date-parts":[[2022,9,10]],"date-time":"2022-09-10T07:59:18Z","timestamp":1662796758000},"page":"18-29","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Regional mutations in CHIKV-ECSA genomes and detection of other viruses in the serum of acute febrile patients by a metagenomic approach in Mato Grosso, Central-Western Brazil, 2018"],"prefix":"10.1016","volume":"576","author":[{"given":"Marcelo Adriano","family":"Mendes dos Santos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Silva","family":"Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janeth Aracely","family":"Ramirez Pavon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Elisa","family":"Viniski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio Lu\u00eds","family":"Campos Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Andrey","family":"Pepato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verg\u00ednia","family":"Correa de Azevedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcio Roberto","family":"Teixeira Nunes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3246-899X","authenticated-orcid":false,"given":"Renata Dezengrini","family":"Slhessarenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.virol.2022.08.013_bib1","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1056\/NEJM198701223160403","article-title":"Human parvovirus infection in pregnancy and hydrops Fetalis","volume":"316","author":"Anand","year":"1987","journal-title":"N. Engl. J. Med."},{"issue":"7","key":"10.1016\/j.virol.2022.08.013_bib2","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1099\/vir.0.82714-0","article-title":"Genetic divergence of Chikungunya viruses in India (1963\u20132006) with special reference to the 2005\u20132006 explosive epidemic","volume":"88","author":"Arankalle","year":"2007","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2022.08.013_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/S0034-8910.2015049006219","article-title":"Chikungunya risk for Brazil","volume":"49","author":"Azevedo","year":"2015","journal-title":"Rev. Saude Publica"},{"key":"10.1016\/j.virol.2022.08.013_bib4","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.idcr.2016.07.008","article-title":"Neonatal encephalitis due to Chikungunya vertical transmission: first report in Brazil","volume":"5","author":"Bandeira","year":"2016","journal-title":"IDCases"},{"issue":"5","key":"10.1016\/j.virol.2022.08.013_bib5","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1089\/cmb.2012.0021","article-title":"SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing","volume":"19","author":"Bankevich","year":"2012","journal-title":"J. Comput. Biol."},{"issue":"1","key":"10.1016\/j.virol.2022.08.013_bib6","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1089\/vim.2012.0061","article-title":"Nonstructural protein 2 (nsP2) of chikungunya virus (CHIKV) enhances protective immunity mediated by a CHIKV envelope protein expressing DNA vaccine","volume":"26","author":"Bao","year":"2013","journal-title":"Viral Immunol."},{"issue":"2","key":"10.1016\/j.virol.2022.08.013_bib7","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1099\/0022-1317-80-2-419","article-title":"Determination and phylogenetic analysis of partial sequences from TT virus isolates","volume":"80","author":"Biagini","year":"1999","journal-title":"J. Gen. Virol."},{"issue":"15","key":"10.1016\/j.virol.2022.08.013_bib8","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"issue":"1","key":"10.1016\/j.virol.2022.08.013_bib9","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nmeth.3176","article-title":"Fast and sensitive protein alignment using DIAMOND","volume":"12","author":"Buchfink","year":"2014","journal-title":"Nat. Methods"},{"issue":"6","key":"10.1016\/j.virol.2022.08.013_bib10","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1590\/0074-02760150123","article-title":"Detection of oropouche virus segment S in patients and in Culex quinquefasciatus in the state of Mato Grosso, Brazil","volume":"110","author":"Cardoso","year":"2015","journal-title":"Mem. Inst. Oswaldo Cruz"},{"issue":"1","key":"10.1016\/j.virol.2022.08.013_bib11","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1099\/vir.0.002360-0","article-title":"Genetic characterization of orthobunyavirus Melao, strains BE AR633512 and BE AR8033, and experimental infection in golden hamsters (Mesocricetus auratus)","volume":"90","author":"Carvalho","year":"2009","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2022.08.013_bib12","author":"Cotmore"},{"issue":"4","key":"10.1016\/j.virol.2022.08.013_bib13","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jcv.2007.05.008","article-title":"Molecular diagnosis and analysis of Chikungunya virus","volume":"39","author":"Edwards","year":"2007","journal-title":"J Clin Virol [Internet]"},{"issue":"6283","key":"10.1016\/j.virol.2022.08.013_bib14","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1126\/science.aaf5036","article-title":"Zika virus in the Americas: early epidemiological and genetic findings","volume":"352","author":"Faria","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.virol.2022.08.013_bib15","author":"Felsenstein"},{"key":"10.1016\/j.virol.2022.08.013_bib16","doi-asserted-by":"crossref","DOI":"10.1590\/0037-8682-0304-2019","article-title":"Human parvovirus B19 genotype 1 in suspected dengue patients of Tef\u00e9, Amazonas State, Brazil","volume":"52","author":"Figueiredo","year":"2019","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"10.1016\/j.virol.2022.08.013_bib17","series-title":"Chikungunya Infection in Pregnancy - Reassuring Maternal and Perinatal Outcomes: a Retrospective Observational Study","author":"Foeller","year":"2021"},{"issue":"8","key":"10.1016\/j.virol.2022.08.013_bib18","article-title":"Arboviral etiologies of acute febrile illnesses in Western South America, 2000\u20132007","volume":"4","author":"Forshey","year":"2010","journal-title":"PLoS Negl Trop Dis [Internet]"},{"issue":"1","key":"10.1016\/j.virol.2022.08.013_bib19","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jcv.2008.03.033","article-title":"Molecular characterization of human erythrovirus B19 strains obtained from patients with several clinical presentations in the Amazon region of Brazil","volume":"43","author":"Freitas","year":"2008","journal-title":"J. Clin. Virol."},{"key":"10.1016\/j.virol.2022.08.013_bib20","series-title":"Hematologic Diseases Associated with Eritrov\u00edrus","author":"Garcia","year":"2009"},{"issue":"12","key":"10.1016\/j.virol.2022.08.013_bib21","doi-asserted-by":"crossref","first-page":"2670","DOI":"10.1099\/vir.0.055509-0","article-title":"Deep sequencing identifies two genotypes and high viral genetic diversity of human pegivirus (GB virus C) in rural Ugandan patients","volume":"94","author":"Ghai","year":"2013","journal-title":"J. Gen. Virol."},{"issue":"6","key":"10.1016\/j.virol.2022.08.013_bib22","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1590\/S0036-46652015000600005","article-title":"Dengue outbreak in Mato Grosso state, midwestern Brazil","volume":"57","author":"Heinen","year":"2015","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"issue":"3","key":"10.1016\/j.virol.2022.08.013_bib23","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1590\/S0036-46652015000300006","article-title":"Saint Louis encephalitis virus in Mato Grosso, central-Western Brazil","volume":"57","author":"Heinen","year":"2015","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"issue":"3","key":"10.1016\/j.virol.2022.08.013_bib24","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1093\/femsre\/fuaa007","article-title":"Human anelloviruses: diverse, omnipresent and commensal members of the virome","volume":"44","author":"Kaczorowska","year":"2020","journal-title":"FEMS Microbiol. Rev."},{"issue":"4","key":"10.1016\/j.virol.2022.08.013_bib25","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1093\/molbev\/mst010","article-title":"MAFFT multiple sequence alignment software version 7: improvements in performance and usability","volume":"30","author":"Katoh","year":"2013","journal-title":"Mol. Biol. Evol."},{"issue":"3","key":"10.1016\/j.virol.2022.08.013_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0151921","article-title":"Metagenomic survey of viral diversity obtained from feces of subantarctic and South American Fur seals. Munderloh UG, editor","volume":"11","author":"Kluge","year":"2016","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.virol.2022.08.013_bib27","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01360-14","article-title":"Standards for sequencing viral genomes in the era of high-throughput sequencing","volume":"5","author":"Ladner","year":"2014","journal-title":"mBio"},{"issue":"9916","key":"10.1016\/j.virol.2022.08.013_bib28","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/S0140-6736(14)60185-9","article-title":"Chikungunya in the Americas","volume":"383","author":"Leparc-Goffart","year":"2014","journal-title":"Lancet"},{"issue":"10","key":"10.1016\/j.virol.2022.08.013_bib29","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.3390\/v3101849","article-title":"Next generation sequencing technologies for insect virus discovery","volume":"3","author":"Liu","year":"2011","journal-title":"Viruses"},{"issue":"20","key":"10.1016\/j.virol.2022.08.013_bib30","doi-asserted-by":"crossref","first-page":"3359","DOI":"10.1093\/bioinformatics\/btv362","article-title":"IBS: an illustrator for the presentation and visualization of biological sequences","volume":"31","author":"Liu","year":"2015","journal-title":"Bioinformatics"},{"issue":"6","key":"10.1016\/j.virol.2022.08.013_bib31","doi-asserted-by":"crossref","first-page":"2729","DOI":"10.1128\/JVI.75.6.2729-2740.2001","article-title":"Evolutionary relationships among parvoviruses: virus\u2013host coevolution among autonomous primate parvoviruses and links between adeno-associated and Avian parvoviruses","volume":"75","author":"Lukashov","year":"2001","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.virol.2022.08.013_bib32","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/mve.12369","article-title":"Natural vertical infection by dengue virus serotype 4, Zika virus and Mayaro virus in Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus","volume":"33","author":"Maia","year":"2019","journal-title":"Med. Vet. Entomol."},{"key":"10.1016\/j.virol.2022.08.013_bib33","year":"2018"},{"issue":"8","key":"10.1016\/j.virol.2022.08.013_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0043206","article-title":"Global Co-existence of two evolutionary lineages of parvovirus B19 1a, different in genome-Wide synonymous positions. Vasilakis N","volume":"7","author":"Molenaar-de Backer","year":"2012","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.virol.2022.08.013_bib35","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.cmi.2018.05.001","article-title":"Epidemiology of acute febrile illness in Latin America","volume":"24","author":"Moreira","year":"2018","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.virol.2022.08.013_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2019\/8048670","article-title":"Molecular and clinical profiles of human pegivirus type 1 infection in individuals living with HIV-1 in the extreme South of Brazil","author":"Mota","year":"2019","journal-title":"BioMed Res. Int."},{"issue":"1","key":"10.1016\/j.virol.2022.08.013_bib37","doi-asserted-by":"crossref","DOI":"10.1186\/1743-422X-7-189","article-title":"Molecular characterization of Chikungunya virus isolates from clinical samples and adult Aedes albopictus mosquitoes emerged from larvae from Kerala, South India","volume":"7","author":"Niyas","year":"2010","journal-title":"Virol. J."},{"issue":"1","key":"10.1016\/j.virol.2022.08.013_bib38","article-title":"Emergence and potential for spread of Chikungunya virus in Brazil","volume":"13","author":"Nunes","year":"2015","journal-title":"BMC Med [Internet"},{"issue":"4","key":"10.1016\/j.virol.2022.08.013_bib39","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0009290","article-title":"Short report: introduction of chikungunya virus ECSA genotype into the Brazilian Midwest and its dispersion through the Americas. Forshey BM","volume":"15","author":"de Oliveira","year":"2021","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.virol.2022.08.013_bib40","series-title":"Uncovering Earth's Virome","first-page":"425","author":"Paez-Espino","year":"2016"},{"issue":"6","key":"10.1016\/j.virol.2022.08.013_bib42","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1128\/JVI.02158-08","article-title":"Role of conserved cysteines in the Alphavirus E3 protein","volume":"83","author":"Parrott","year":"2009","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2022.08.013_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcv.2021.105056","article-title":"Neurological infection by chikungunya and a triple arbovirus coinfection in Mato Grosso, central Western Brazil during 2019","volume":"146","author":"Pavon","year":"2022","journal-title":"J. Clin. Virol."},{"issue":"5","key":"10.1016\/j.virol.2022.08.013_bib44","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1093\/sysbio\/syy032","article-title":"Posterior summarization in bayesian phylogenetics using tracer 1.7. Susko E","volume":"67","author":"Rambaut","year":"2018","journal-title":"Syst. Biol."},{"key":"10.1016\/j.virol.2022.08.013_bib45","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.antiviral.2013.12.010","article-title":"Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo","volume":"103","author":"Rathore","year":"2014","journal-title":"Antivir. Res."},{"key":"10.1016\/j.virol.2022.08.013_bib46","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/nbt.4306","article-title":"Minimum information about an uncultivated virus genome (MIUViG)","author":"Roux","year":"2019","journal-title":"Nat. Biotechnol."},{"issue":"9","key":"10.1016\/j.virol.2022.08.013_bib47","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1128\/JCM.00877-16","article-title":"Coinfections of Zika and chikungunya viruses in Bahia, Brazil, identified by metagenomic next-generation sequencing. Loeffelholz MJ","volume":"54","author":"Sardi","year":"2016","journal-title":"J. Clin. Microbiol."},{"issue":"7","key":"10.1016\/j.virol.2022.08.013_bib48","doi-asserted-by":"crossref","first-page":"e263","DOI":"10.1371\/journal.pmed.0030263","article-title":"Genome Microevolution of chikungunya viruses causing the Indian ocean outbreak. IV HV, editor","volume":"3","author":"Schuffenecker","year":"2006","journal-title":"PLoS Med."},{"key":"10.1016\/j.virol.2022.08.013_bib49","series-title":"Boletim Epidemiol\u00f3gico n\u00b0 45 Ed. 01 SE 52\/2017. Dengue, Febre Chikungunya e Febre pelo Virus Zika","first-page":"9","author":"Secretaria Estadual de Sa\u00fade de MT","year":"2017"},{"issue":"1","key":"10.1016\/j.virol.2022.08.013_bib51","doi-asserted-by":"crossref","DOI":"10.1186\/s12985-020-01427-6","article-title":"Human pegivirus (HPgV, GBV-C) RNA in volunteer blood donors from a public hemotherapy service in Northern Brazil","volume":"17","author":"Silva","year":"2020","journal-title":"Virol. J."},{"issue":"4","key":"10.1016\/j.virol.2022.08.013_bib52","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.tracli.2019.06.005","article-title":"Human pegivirus-1 (HPgV-1) RNA prevalence and genotypes in volunteer blood donors from the Brazilian Amazon","volume":"26","author":"Slavov","year":"2019","journal-title":"Transfus. Clin. Biol."},{"issue":"2","key":"10.1016\/j.virol.2022.08.013_bib53","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.transci.2019.01.002","article-title":"Human pegivirus-1 (HPgV-1, GBV-C) RNA prevalence and genotype diversity among volunteer blood donors from an intrahospital hemotherapy service in Southern Brazil","volume":"58","author":"Slavov","year":"2019","journal-title":"Transfus. Apher. Sci."},{"issue":"2","key":"10.1016\/j.virol.2022.08.013_bib54","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.coviro.2013.03.007","article-title":"Virus discovery: one step beyond","volume":"3","author":"Smits","year":"2013","journal-title":"Curr Opin Virol"},{"key":"10.1016\/j.virol.2022.08.013_bib55","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.actatropica.2018.12.019","article-title":"Arbovirus investigation in patients from Mato Grosso during Zika and chikungunya virus introduction in Brazil, 2015\u20132016","volume":"190","author":"de Souza Costa","year":"2019","journal-title":"Acta Trop."},{"key":"10.1016\/j.virol.2022.08.013_bib56","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.virol.2017.11.001","article-title":"Discovery of novel anelloviruses in small mammals expands the host range and diversity of the Anelloviridae","volume":"514","author":"de Souza","year":"2018","journal-title":"Virology"},{"issue":"2","key":"10.1016\/j.virol.2022.08.013_bib57","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1128\/JCM.43.2.716-720.2005","article-title":"Characterization of virus isolates by particle-associated nucleic acid PCR","author":"Stang","year":"2005","journal-title":"J Clin Microbiol [Internet]"},{"issue":"1","key":"10.1016\/j.virol.2022.08.013_bib58","doi-asserted-by":"crossref","DOI":"10.1093\/ve\/vey016","article-title":"Bayesian phylogenetic and phylodynamic data integration using BEAST 1.10","volume":"4","author":"Suchard","year":"2018","journal-title":"Virus Evol"},{"issue":"4","key":"10.1016\/j.virol.2022.08.013_bib59","doi-asserted-by":"crossref","first-page":"3022","DOI":"10.1093\/molbev\/msab120","article-title":"MEGA11: molecular evolutionary genetics analysis version 11","volume":"38","author":"Tamura","year":"2021","journal-title":"Mol. Biol. Evol."},{"issue":"10","key":"10.1016\/j.virol.2022.08.013_bib60","doi-asserted-by":"crossref","first-page":"2941","DOI":"10.1099\/vir.0.82037-0","article-title":"Phylogenetic analysis of human parvovirus B19, indicating two subgroups of genotype 1 in Vietnamese patients","volume":"87","author":"Toan","year":"2006","journal-title":"J. Gen. Virol."},{"issue":"12","key":"10.1016\/j.virol.2022.08.013_bib61","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.0030201","article-title":"A single mutation in chikungunya virus affects vector specificity and epidemic potential. Holmes EC","volume":"3","author":"Tsetsarkin","year":"2007","journal-title":"PLoS Pathog."},{"issue":"8","key":"10.1016\/j.virol.2022.08.013_bib62","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0006835","article-title":"Epistatic roles of E2 glycoprotein mutations in adaptation of chikungunya virus to Aedes albopictus and Ae. Aegypti mosquitoes. Schneider BS","volume":"4","author":"Tsetsarkin","year":"2009","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.virol.2022.08.013_bib63","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002412","article-title":"Sequential adaptive mutations enhance efficient vector switching by chikungunya virus and its epidemic emergence","volume":"7","author":"Tsetsarkin","year":"2011","journal-title":"PLoS Pathog."},{"issue":"1","key":"10.1016\/j.virol.2022.08.013_bib64","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms5084","article-title":"Multipeaked adaptive landscape for chikungunya virus evolution predicts continued fitness optimization in Aedes albopictus mosquitoes","volume":"5","author":"Tsetsarkin","year":"2014","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.virol.2022.08.013_bib65","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1007\/s00705-019-04174-4","article-title":"Genome sequences of chikungunya virus isolates circulating in Midwestern Brazil","volume":"164","author":"Vasconcellos","year":"2019","journal-title":"Arch. Virol."},{"issue":"1","key":"10.1016\/j.virol.2022.08.013_bib66","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s12560-012-9096-7","article-title":"Presence of torque teno virus (TTV) in tap Water in public schools from southern Brazil","volume":"5","author":"Vecchia","year":"2012","journal-title":"Food Environ Virol"},{"issue":"2","key":"10.1016\/j.virol.2022.08.013_bib67","first-page":"105","article-title":"The emergence of chikungunya ECSA lineage in a Mayaro endemic region on the southern border of the Amazon forest","volume":"5","author":"Vieira","year":"2020","journal-title":"Trav. Med. Infect. Dis."},{"issue":"6","key":"10.1016\/j.virol.2022.08.013_bib68","doi-asserted-by":"crossref","first-page":"821","DOI":"10.3892\/br.2015.508","article-title":"Molecular characterization of human Torque Teno virus","volume":"3","author":"Wei","year":"2015","journal-title":"Biomed Rep"},{"issue":"2","key":"10.1016\/j.virol.2022.08.013_bib69","doi-asserted-by":"crossref","first-page":"e1485","DOI":"10.1371\/journal.pntd.0001485","article-title":"Virus identification in unknown tropical febrile illness cases using deep sequencing","volume":"6","author":"Yozwiak","year":"2012","journal-title":"PLoS Neglected Trop. Dis."},{"issue":"6","key":"10.1016\/j.virol.2022.08.013_bib70","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1590\/0074-0276140108","article-title":"Molecular detection of Mayaro virus during a dengue outbreak in the state of Mato Grosso, Central-West Brazil","volume":"109","author":"Zuchi","year":"2014","journal-title":"Mem. Inst. Oswaldo Cruz"}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682222001441?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682222001441?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:56:53Z","timestamp":1758589013000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682222001441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":68,"alternative-id":["S0042682222001441"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2022.08.013","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Regional mutations in CHIKV-ECSA genomes and detection of other viruses in the serum of acute febrile patients by a metagenomic approach in Mato Grosso, Central-Western Brazil, 2018","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2022.08.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}