{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T18:30:05Z","timestamp":1791916205213,"version":"4.3.4"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.virol.2024.109983","type":"journal-article","created":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T16:45:04Z","timestamp":1704473104000},"page":"109983","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Cucumber mosaic virus impairs the physiological homeostasis of Panax notoginseng and induces saponin-mediated resistance"],"prefix":"10.1016","volume":"591","author":[{"given":"Yongchao","family":"Cheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianrui","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daoyong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiding","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahong","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1314-1262","authenticated-orcid":false,"given":"Dehui","family":"Xi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.virol.2024.109983_bib1","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1007\/s00344-012-9272-x","article-title":"Role of secondary metabolites and brassinosteroids in plant defense against environmental stresses","volume":"32","author":"Bartwal","year":"2013","journal-title":"J. Plant Growth Regul."},{"issue":"5","key":"10.1016\/j.virol.2024.109983_bib2","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1093\/jxb\/ert375","article-title":"ROS as key players in plant stress signalling","volume":"65","author":"Baxter","year":"2014","journal-title":"J. Exp. Bot."},{"issue":"2","key":"10.1016\/j.virol.2024.109983_bib3","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s00425-017-2785-6","article-title":"Tobacco alpha-expansin EXPA4 plays a role in Nicotiana benthamiana defence against Tobacco mosaic virus","volume":"247","author":"Chen","year":"2018","journal-title":"Planta"},{"issue":"3","key":"10.1016\/j.virol.2024.109983_bib4","first-page":"555","article-title":"Occurrence of Cucumber mosaic virus subgroup II and its genetic diversity in Sichuan, southwest of China","volume":"100","author":"Fei","year":"2018","journal-title":"J. Plant Physiol."},{"key":"10.1016\/j.virol.2024.109983_bib5","doi-asserted-by":"crossref","DOI":"10.1111\/ppl.14012","article-title":"Catalases mediate tobacco resistance to virus infection through crosstalk between salicylic acid and auxin signaling pathways","volume":"175","author":"Huang","year":"2023","journal-title":"Physiol. Plant.."},{"key":"10.1016\/j.virol.2024.109983_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.pmpp.2021.101751","article-title":"Influence of RNA interference of phytochrome A1 gene on activity of antioxidant system in cotton","volume":"117","author":"Kamburova","year":"2022","journal-title":"Physiol. Mol. Plant Pathol."},{"key":"10.1016\/j.virol.2024.109983_bib7","first-page":"266","article-title":"Ginsenoside Rb1 is an immune-stimulatory agent with antiviral activity against enterovirus","volume":"71","author":"Kang","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.virol.2024.109983_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.virusres.2020.198172","article-title":"The C-terminal region of the 2a protein and 2b protein of cucumber mosaic virus are involved in the induction of shoestring-like leaf blade in tomato","volume":"289","author":"Khaing","year":"2020","journal-title":"Virus Res."},{"issue":"3","key":"10.1016\/j.virol.2024.109983_bib9","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jgr.2017.11.008","article-title":"Dammarane-type triterpene oligoglycosides from the leaves and stems of Panax notoginseng and their antiinflammatory activities","volume":"43","author":"Li","year":"2019","journal-title":"J. Ginseng Res."},{"issue":"6","key":"10.1016\/j.virol.2024.109983_bib10","doi-asserted-by":"crossref","first-page":"4199","DOI":"10.15244\/pjoes\/120514","article-title":"Effects of lime application on activities of related enzymes and protein expression of saponin metabolism of Panax notoginseng under cadmium stress","volume":"29","author":"Li","year":"2020","journal-title":"Pol. J. Environ. Stud."},{"key":"10.1016\/j.virol.2024.109983_bib11","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.indcrop.2017.05.052","article-title":"Soil water stress attenuate the growth and development but enhance the saponin synthesis of Panax notogesing during flowering stage","volume":"108","author":"Liao","year":"2017","journal-title":"Ind. Crops Prod."},{"issue":"2","key":"10.1016\/j.virol.2024.109983_bib12","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1111\/ppl.12866","article-title":"Quantitative ROS bioreporters: a robust toolkit for studying biological roles of ROS in response to abiotic and biotic stresses","volume":"165","author":"Lim","year":"2019","journal-title":"Physiol. Plant"},{"issue":"6","key":"10.1016\/j.virol.2024.109983_bib13","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1111\/tpj.14899","article-title":"Factors affecting freezing tolerance: a comparative transcriptomics study between field and artificial cold acclimations in overwintering evergreens","volume":"103","author":"Liu","year":"2020","journal-title":"Plant J."},{"issue":"12","key":"10.1016\/j.virol.2024.109983_bib14","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1007\/s13258-019-00865-z","article-title":"A transcriptome analysis uncovers Panax notoginseng resistance to Fusarium solani induced by methyl jasmonate","volume":"41","author":"Liu","year":"2019","journal-title":"Genes Genom"},{"issue":"1","key":"10.1016\/j.virol.2024.109983_bib15","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s42161-022-01262-4","article-title":"First report of tomato spotted wilt virus (TSWV) infecting Panax notoginseng (Burk.) F.H. Chen in China","volume":"105","author":"Ma","year":"2023","journal-title":"J. Plant Pathol."},{"issue":"3","key":"10.1016\/j.virol.2024.109983_bib16","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1364-3703.2011.00749.x","article-title":"Cucumber mosaic virus: viral genes as virulence determinants","volume":"13","author":"Mochizuki","year":"2012","journal-title":"Mol. Plant Pathol."},{"key":"10.1016\/j.virol.2024.109983_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2022.870976","article-title":"Regulation of plant tannin synthesis in crop species","volume":"13","author":"Mora","year":"2022","journal-title":"Front. Genet."},{"issue":"2","key":"10.1016\/j.virol.2024.109983_bib18","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s00425-022-03825-2","article-title":"Vitamin E protects from lipid peroxidation during winter stress in the seagrass Cymodocea nodosa","volume":"255","author":"Munn\u00e9-Bosch","year":"2022","journal-title":"Planta"},{"key":"10.1016\/j.virol.2024.109983_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2020.595095","article-title":"Lowering nitrogen and increasing potassium application level can improve the yield and quality of Panax notoginseng","volume":"11","author":"Ou","year":"2020","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.virol.2024.109983_bib20","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.plaphy.2020.02.030","article-title":"Exogenous vanillic acid enhances salt tolerance of tomato: insight into plant antioxidant defense and glyoxalase systems","volume":"150","author":"Parvin","year":"2020","journal-title":"Plant Physiol. Biochem."},{"key":"10.1016\/j.virol.2024.109983_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.112955","article-title":"Anticoagulant active ingredients identification of total saponin extraction of different Panax medicinal plants based on grey relational analysis combined with UPLC-MS and molecular docking","volume":"260","author":"Ren","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.virol.2024.109983_bib22","series-title":"Panax Notoginseng (Notoginseng or Sanqi) BT - Encyclopedia of Plant Viruses and Viroids","first-page":"1712","author":"Sastry","year":"2019"},{"issue":"9","key":"10.1016\/j.virol.2024.109983_bib23","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1111\/j.1364-3703.2011.00752.x","article-title":"Top 10 plant viruses in molecular plant pathology","volume":"12","author":"Scholthof","year":"2011","journal-title":"Mol. Plant Pathol."},{"issue":"6","key":"10.1016\/j.virol.2024.109983_bib24","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1094\/MPMI-12-10-0290","article-title":"The 2b silencing suppressor of a mild strain of Cucumber mosaic virus alone is sufficient for synergistic interaction with Tobacco mosaic virus and induction of severe leaf malformation in 2b-transgenic tobacco plants","volume":"24","author":"Siddiqui","year":"2011","journal-title":"Mol. Plant Microbe Interact."},{"issue":"4","key":"10.1016\/j.virol.2024.109983_bib25","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/jobm.201600464","article-title":"Diversity and composition of rhizospheric soil and root endogenous bacteria in Panax notoginseng during continuous cropping practices","volume":"57","author":"Tan","year":"2017","journal-title":"J. Basic Microbiol."},{"key":"10.1016\/j.virol.2024.109983_bib26","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2019.01448","article-title":"Dual mode of the saponin aescin in plant protection: antifungal agent and plant defense elicitor","volume":"10","author":"Trd\u00e1","year":"2019","journal-title":"Front. Plant Sci."},{"issue":"2","key":"10.1016\/j.virol.2024.109983_bib27","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1111\/mpp.12892","article-title":"Cucumber mosaic virus 2b proteins inhibit virus-induced aphid resistance in tobacco","volume":"21","author":"Tungadi","year":"2020","journal-title":"Mol. Plant Pathol."},{"issue":"14","key":"10.1016\/j.virol.2024.109983_bib28","doi-asserted-by":"crossref","first-page":"3313","DOI":"10.1093\/jxb\/ery198","article-title":"ROS and RNS: key signalling molecules in plants","volume":"69","author":"Turkan","year":"2018","journal-title":"J. Exp. Bot."},{"issue":"4","key":"10.1016\/j.virol.2024.109983_bib29","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/jph.12049","article-title":"Expression of the CMV-CP gene in synechocystis 6803 affects cyanobacterial photosynthesis","volume":"161","author":"Wang","year":"2013","journal-title":"J. Phytopathol."},{"issue":"2","key":"10.1016\/j.virol.2024.109983_bib30","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/bab.1580","article-title":"Construct a gene-to-metabolite network to screen the key genes of triterpene saponin biosynthetic pathway in Panax notoginseng","volume":"65","author":"Wang","year":"2018","journal-title":"Biotechnol. Appl. Biochem."},{"issue":"11","key":"10.1016\/j.virol.2024.109983_bib31","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.tplants.2020.08.001","article-title":"Fine-tuning of RBOH-mediated ROS signaling in plant immunity","volume":"25","author":"Wang","year":"2020","journal-title":"Trends Plant Sci."},{"issue":"6","key":"10.1016\/j.virol.2024.109983_bib32","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1007\/s00705-010-0672-6","article-title":"Identification and molecular characterization of a new potyvirus from Panax notoginseng","volume":"155","author":"Yan","year":"2010","journal-title":"Arch. Virol."},{"key":"10.1016\/j.virol.2024.109983_bib33","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/s00425-022-04010-1","article-title":"Glucose-6-phosphate dehydrogenase promotes the infection of chilli veinal mottle virus through affecting ROS signaling in Nicotiana benthamiana","volume":"256","author":"Yang","year":"2022","journal-title":"Planta"},{"key":"10.1016\/j.virol.2024.109983_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.jplph.2021.153466","article-title":"Melatonin increases leaf disease resistance and saponin biosynthesis in Panax notogiseng","volume":"263","author":"Yang","year":"2021","journal-title":"J. Plant Physiol."},{"key":"10.1016\/j.virol.2024.109983_bib35","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.jplph.2018.08.013","article-title":"N gene enhances resistance to Chilli veinal mottle virus and hypersensitivity to salt stress in tobacco","volume":"230","author":"Yang","year":"2018","journal-title":"J. Plant Physiol."},{"key":"10.1016\/j.virol.2024.109983_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2019.117243","article-title":"Identification of unhealthy Panax notoginseng from different geographical origins by means of multi-label classification","volume":"222","author":"Yang","year":"2019","journal-title":"Spectrochim. Acta"},{"key":"10.1016\/j.virol.2024.109983_bib37","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1111\/ppa.13763","article-title":"HCPro affects heterologous virus infection through salicylic acid and auxin pathways","volume":"72","author":"Zeng","year":"2023","journal-title":"Plant Pathol."},{"issue":"6","key":"10.1016\/j.virol.2024.109983_bib38","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.molp.2017.02.011","article-title":"The Medicinal herb Panax notoginseng genome provides insights into ginsenoside biosynthesis and genome evolution","volume":"10","author":"Zhang","year":"2017","journal-title":"Mol. Plant"},{"key":"10.1016\/j.virol.2024.109983_bib39","doi-asserted-by":"crossref","first-page":"396","DOI":"10.7150\/ijbs.34978","article-title":"Ophiopogon saponin C1 inhibits lung tumors by stabilizing endothelium permeability via inhibition of PKC\u03b4","volume":"16","author":"Zhang","year":"2020","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.virol.2024.109983_bib40","article-title":"Detection and diversity analysis of viruses infecting Panax notoginrseng in Yunnan province, Sichuan province and Chongqing municipality","volume":"59","author":"Zheng","year":"2022","journal-title":"J. Sicuan Univ: Nat Si Ed"},{"key":"10.1016\/j.virol.2024.109983_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.plgene.2018.08.001","article-title":"Transcriptome analysis of main roots of Panax notoginseng identifies genes involved in saponin biosynthesis under arsenic stress","volume":"16","author":"Zu","year":"2018","journal-title":"Plant Gene"}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682224000047?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682224000047?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T04:54:28Z","timestamp":1740804868000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682224000047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":41,"alternative-id":["S0042682224000047"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2024.109983","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cucumber mosaic virus impairs the physiological homeostasis of Panax notoginseng and induces saponin-mediated resistance","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2024.109983","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"109983"}}