{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T02:54:06Z","timestamp":1787453646306,"version":"build-2736575974"},"reference-count":113,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003977","name":"Israel Science Foundation","doi-asserted-by":"publisher","award":["3479\/24"],"award-info":[{"award-number":["3479\/24"]}],"id":[{"id":"10.13039\/501100003977","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006031","name":"United States Israel Binational Agricultural Research and Development Fund","doi-asserted-by":"publisher","award":["IS-5596-23"],"award-info":[{"award-number":["IS-5596-23"]}],"id":[{"id":"10.13039\/100006031","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.virol.2025.110462","type":"journal-article","created":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:15:14Z","timestamp":1740136514000},"page":"110462","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Immunity responses as checkpoints for efficient transmission of begomoviruses by whiteflies"],"prefix":"10.1016","volume":"605","author":[{"given":"Ilana","family":"Kuzminsky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6628-8308","authenticated-orcid":false,"given":"Murad","family":"Ghanim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virol.2025.110462_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep17696","article-title":"Rapid accumulation and low degradation: key parameters of Tomato yellow leaf curl virus persistence in its insect vector Bemisia tabaci","volume":"5","author":"Becker","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2025.110462_bib2","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1146\/annurev-ento-112408-085301","article-title":"Beyond Drosophila: RNAi in vivo and functional genomics in insects","volume":"55","author":"Bell\u00e9s","year":"2010","journal-title":"Annu. Rev. Entomol."},{"key":"10.1016\/j.virol.2025.110462_bib3","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/j.cell.2007.10.048","article-title":"Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila","volume":"131","author":"Berry","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.virol.2025.110462_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/cells11050833","article-title":"Topical spray of dsRNA induces mortality and inhibits Chilli leaf curl virus transmission by Bemisia tabaci Asia II 1","volume":"11","author":"Chakraborty","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.virol.2025.110462_bib5","doi-asserted-by":"crossref","first-page":"13045","DOI":"10.1074\/jbc.M110636200","article-title":"The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi","volume":"277","author":"Chen","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virol.2025.110462_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12915-016-0321-y","article-title":"The draft genome of whitefly Bemisia tabaci MEAM1, a global crop pest, provides novel insights into virus transmission, host adaptation, and insecticide resistance","volume":"14","author":"Chen","year":"2016","journal-title":"BMC Biol."},{"key":"10.1016\/j.virol.2025.110462_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006727","article-title":"Autophagy pathway induced by a plant virus facilitates viral spread and transmission by its insect vector","volume":"13","author":"Chen","year":"2017","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2025.110462_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007510","article-title":"Fibrillar structures induced by a plant reovirus target mitochondria to activate typical apoptotic response and promote viral infection in insect vectors","volume":"15","author":"Chen","year":"2019","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2025.110462_bib9","doi-asserted-by":"crossref","first-page":"9640","DOI":"10.3390\/ijms22179640","article-title":"The roles of c-Jun N-Terminal Kinase (JNK) in infectious diseases","volume":"22","author":"Chen","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.virol.2025.110462_bib10","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1186\/s12929-023-00899-2","article-title":"The role of autophagy in viral infections","volume":"30","author":"Chen","year":"2023","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.virol.2025.110462_bib11","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1017\/S0007485307005159","article-title":"Biotype-dependent secondary symbiont communities in sympatric populations of Bemisia tabaci","volume":"97","author":"Chiel","year":"2007","journal-title":"Bull. Entomol. Res."},{"key":"10.1016\/j.virol.2025.110462_bib12","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1017\/S0007485311000083","article-title":"Further insights into the strange role of bacterial endosymbionts in whitefly, Bemisia tabaci: comparison of secondary symbionts from biotypes B and Q in China","volume":"101","author":"Chu","year":"2011","journal-title":"Bull. Entomol. Res."},{"key":"10.1016\/j.virol.2025.110462_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0007436","article-title":"The Imd pathway is involved in antiviral immune responses in Drosophila","volume":"4","author":"Costa","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.virol.2025.110462_bib14","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S2095-3119(12)60007-0","article-title":"Back to basics: are begomoviruses whitefly pathogens?","volume":"11","author":"Czosnek","year":"2012","journal-title":"J. Integr. Agric."},{"key":"10.1016\/j.virol.2025.110462_bib15","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-32913-1","article-title":"Distribution and phylogenetics of whiteflies and their endosymbiont relationships after the Mediterranean species invasion in Brazil","volume":"8","author":"de Moraes","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2025.110462_bib16","doi-asserted-by":"crossref","first-page":"302","DOI":"10.3389\/fphys.2019.00302","article-title":"Transcriptome profiling of the whitefly Bemisia tabaci MED in response to single infection of Tomato yellow leaf curl virus, Tomato chlorosis virus, and their co-infection","volume":"10","author":"Ding","year":"2019","journal-title":"Front. Physiol."},{"key":"10.1016\/j.virol.2025.110462_bib17","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1159\/000346388","article-title":"Autophagy and viruses: adversaries or allies?","volume":"5","author":"Dong","year":"2013","journal-title":"J. Innate Immun."},{"key":"10.1016\/j.virol.2025.110462_bib18","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.190009","article-title":"Role of autophagy during the replication and pathogenesis of common mosquito-borne flavi- and alphaviruses","volume":"9","author":"Echavarria-Consuegra","year":"2019","journal-title":"Open Biol."},{"key":"10.1016\/j.virol.2025.110462_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep02876","article-title":"Tomato yellow leaf curl virus alters the host preferences of its vector Bemisia tabaci","volume":"3","author":"Fang","year":"2013","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2025.110462_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2022.1040547","article-title":"Cotton leaf curl Multan virus differentially regulates innate antiviral immunity of whitefly (Bemisia tabaci) vector to promote cryptic species-dependent virus acquisition","volume":"13","author":"Farooq","year":"2022","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.virol.2025.110462_bib21","doi-asserted-by":"crossref","first-page":"E255","DOI":"10.1038\/ncb1101-e255","article-title":"Organelle-specific initiation of cell death pathways","volume":"3","author":"Ferri","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.virol.2025.110462_bib22","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1094\/PHYTO-07-19-0273-FI","article-title":"Transmission of begomoviruses and other whitefly-borne viruses: dependence on the vector species","volume":"110","author":"Fiallo-Oliv\u00e9","year":"2020","journal-title":"Phytopathology"},{"key":"10.1016\/j.virol.2025.110462_bib23","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/35888","article-title":"Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans","volume":"391","author":"Fire","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.virol.2025.110462_bib24","doi-asserted-by":"crossref","first-page":"895","DOI":"10.3390\/plants9070895","article-title":"Feeding behavior and virus-transmission ability of insect vectors exposed to systemic insecticides","volume":"9","author":"Garzo","year":"2020","journal-title":"Plants"},{"key":"10.1016\/j.virol.2025.110462_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12985-018-0926-6","article-title":"Transcriptome profiling of whitefly guts in response to Tomato yellow leaf curl virus infection","volume":"15","author":"Geng","year":"2018","journal-title":"Virol. J."},{"key":"10.1016\/j.virol.2025.110462_bib26","first-page":"171","article-title":"Localization of tomato yellow leaf curl virus in its whitefly vector Bemisia tabaci. Tomato yellow leaf curl virus disease: management","author":"Ghanim","year":"2007","journal-title":"Molecular Biology, Breeding for Resistance"},{"key":"10.1016\/j.virol.2025.110462_bib27","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.ibmb.2007.04.006","article-title":"Tissue-specific gene silencing by RNA interference in the whitefly Bemisia tabaci (Gennadius)","volume":"37","author":"Ghanim","year":"2007","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.virol.2025.110462_bib28","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.3390\/v13091808","article-title":"Factors determining transmission of persistent viruses by Bemisia tabaci and emergence of new virus\u2013vector relationships","volume":"13","author":"Ghosh","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.virol.2025.110462_bib29","doi-asserted-by":"crossref","first-page":"9310","DOI":"10.1128\/JVI.00423-10","article-title":"The transmission efficiency of Tomato yellow leaf curl virus by the whitefly Bemisia tabaci is correlated with the presence of a specific symbiotic bacterium species","volume":"84","author":"Gottlieb","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2025.110462_bib30","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.01067-23","article-title":"The essential role of clathrin-mediated endocytosis and early endosomes in the trafficking of begomoviruses through the primary salivary glands of their whitefly vectors","volume":"97","author":"Guo","year":"2023","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2025.110462_bib31","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/ncb2738","article-title":"ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death","volume":"15","author":"Han","year":"2013","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.virol.2025.110462_bib32","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/16729","article-title":"Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase","volume":"397","author":"Harding","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.virol.2025.110462_bib33","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S1097-2765(03)00105-9","article-title":"An integrated stress response regulates amino acid metabolism and resistance to oxidative stress","volume":"11","author":"Harding","year":"2003","journal-title":"Mol Cell"},{"key":"10.1016\/j.virol.2025.110462_bib34","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.virol.2017.10.008","article-title":"Comparative transcriptome analysis reveals networks of genes activated in the whitefly, Bemisia tabaci when fed on tomato plants infected with Tomato yellow leaf curl virus","volume":"513","author":"Hasegawa","year":"2018","journal-title":"Virology"},{"key":"10.1016\/j.virol.2025.110462_bib35","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/sj.cdd.4401833","article-title":"Viruses, endoplasmic reticulum stress, and interferon responses","volume":"13","author":"He","year":"2006","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.virol.2025.110462_bib36","doi-asserted-by":"crossref","first-page":"16928","DOI":"10.1073\/pnas.1820132117","article-title":"A plant DNA virus replicates in the salivary glands of its insect vector via recruitment of host DNA synthesis machinery","volume":"117","author":"He","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.virol.2025.110462_bib37","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.0709178104","article-title":"Plant virus transmission from the insect point of view","volume":"104","author":"Hohn","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.virol.2025.110462_bib38","series-title":"Encyclopedia of Microbiology","first-page":"430","article-title":"Plant pathogens: DNA viruses","author":"Hohn","year":"2009"},{"key":"10.1016\/j.virol.2025.110462_bib39","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1083\/jcb.200712091","article-title":"Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis","volume":"182","author":"Hou","year":"2008","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.virol.2025.110462_bib40","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.virol.2019.03.015","article-title":"Apoptosis as a primary defense mechanism in response to viral infection in invasive fire ant Solenopsis invicta","volume":"531","author":"Hsu","year":"2019","journal-title":"Virology"},{"key":"10.1016\/j.virol.2025.110462_bib41","article-title":"Rice ragged stunt virus-induced apoptosis affects virus transmission from its insect vector, the brown planthopper to the rice plant","volume":"5","author":"Huang","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2025.110462_bib42","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1038\/ni1112","article-title":"Toll-like receptor control of the adaptive immune responses","volume":"5","author":"Iwasaki","year":"2004","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.virol.2025.110462_bib43","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.15252\/embr.201643426","article-title":"The ins and outs of endoplasmic reticulum-controlled lipid biosynthesis","volume":"18","author":"Jacquemyn","year":"2017","journal-title":"EMBO Rep."},{"key":"10.1016\/j.virol.2025.110462_bib44","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1111\/imb.12842","article-title":"Association of endoplasmic reticulum associated degradation (ERAD) with the transmission of Liberibacter solanacearum by its psyllid vector","volume":"32","author":"Jassar","year":"2023","journal-title":"Insect Mol. Biol."},{"key":"10.1016\/j.virol.2025.110462_bib45","doi-asserted-by":"crossref","first-page":"115","DOI":"10.5424\/sjar\/2004021-68","article-title":"Short communication. Effect of Bemisia tabaci biotype in the transmission of Tomato Yellow leaf curl sardinia virus (TYLCSV-ES) between tomato and common weeds","volume":"2","author":"Jiang","year":"2004","journal-title":"Spanish J. Agric. Res."},{"key":"10.1016\/j.virol.2025.110462_bib46","doi-asserted-by":"crossref","first-page":"329","DOI":"10.3390\/v8120329","article-title":"RNA interference in insect vectors for plant viruses","volume":"8","author":"Kanakala","year":"2016","journal-title":"Viruses"},{"key":"10.1016\/j.virol.2025.110462_bib47","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.3389\/fpls.2016.01702","article-title":"Implication of the whitefly Bemisia tabaci Cyclophilin B protein in the Transmission of Tomato yellow leaf curl virus","volume":"7","author":"Kanakala","year":"2016","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.virol.2025.110462_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0213946","article-title":"Global genetic diversity and geographical distribution of Bemisia tabaci and its bacterial endosymbionts","volume":"14","author":"Kanakala","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.virol.2025.110462_bib49","doi-asserted-by":"crossref","first-page":"557","DOI":"10.3389\/fphys.2019.00557","article-title":"Plant-Mediated silencing of the whitefly Bemisia tabaci Cyclophilin B and heat shock protein 70 impairs insect development and virus transmission","volume":"10","author":"Kanakala","year":"2019","journal-title":"Front. Physiol."},{"key":"10.1016\/j.virol.2025.110462_bib50","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1099\/vir.0.042846-0","article-title":"Apoptosis in mosquito salivary glands: Sindbis virus-associated and tissue homeostasis","volume":"93","author":"Kelly","year":"2012","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2025.110462_bib51","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1038\/nrd2755","article-title":"Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities","volume":"7","author":"Kim","year":"2008","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.virol.2025.110462_bib52","doi-asserted-by":"crossref","first-page":"3636","DOI":"10.1242\/jcs.028654","article-title":"Overexpressed cyclophilin B suppresses apoptosis associated with ROS and Ca2+ homeostasis after ER stress","volume":"121","author":"Kim","year":"2008","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.virol.2025.110462_bib53","doi-asserted-by":"crossref","first-page":"5652","DOI":"10.1128\/JVI.00071-14","article-title":"Implication of the bacterial endosymbiont Rickettsia spp. in Interactions of the whitefly Bemisia tabaci with Tomato yellow leaf curl virus","volume":"88","author":"Kliot","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2025.110462_bib54","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2020.00917","article-title":"The use of engineered plant viruses in a trans-kingdom silencing strategy against their insect vectors","volume":"11","author":"Kolliopoulou","year":"2020","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.virol.2025.110462_bib55","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1080\/08830180305210","article-title":"Physiological significance of apoptosis during animal virus infection","volume":"22","author":"Koyama","year":"2003","journal-title":"Int. Rev. Immunol."},{"key":"10.1016\/j.virol.2025.110462_bib56","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.virol.2008.02.016","article-title":"Autophagic machinery activated by dengue virus enhances virus replication","volume":"374","author":"Lee","year":"2008","journal-title":"Virology"},{"key":"10.1016\/j.virol.2025.110462_bib57","doi-asserted-by":"crossref","first-page":"4929","DOI":"10.1128\/JVI.03571-12","article-title":"Multiple forms of vector manipulation by a plant-infecting virus: Bemisia tabaci and Tomato yellow leaf curl virus","volume":"87","author":"Liu","year":"2013","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2025.110462_bib58","doi-asserted-by":"crossref","first-page":"3330","DOI":"10.1128\/JVI.02507-10","article-title":"Global analysis of the transcriptional response of whitefly to Tomato yellow leaf curl China virus reveals the relationship of coevolved adaptations","volume":"85","author":"Luan","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2025.110462_bib59","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1146\/annurev-virology-091919-100543","article-title":"Interaction of viruses with the insect intestine","volume":"8","author":"Ma","year":"2021","journal-title":"Annu Rev Virol"},{"key":"10.1016\/j.virol.2025.110462_bib60","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/nrm3735","article-title":"Self-consumption: the interplay of autophagy and apoptosis","volume":"15","author":"Mari\u00f1o","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.virol.2025.110462_bib61","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0108363","article-title":"Diversity and localization of bacterial endosymbionts from whitefly species collected in Brazil","volume":"9","author":"Marubayashi","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.virol.2025.110462_bib62","doi-asserted-by":"crossref","first-page":"10849","DOI":"10.1128\/JVI.01151-07","article-title":"West Nile virus infection activates the unfolded protein response, leading to CHOP induction and apoptosis","volume":"81","author":"Medigeshi","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2025.110462_bib63","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/35100529","article-title":"Toll-like receptors and innate immunity","volume":"1","author":"Medzhitov","year":"2001","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.virol.2025.110462_bib64","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1080\/21505594.2019.1605803","article-title":"The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections","volume":"10","author":"Mehrbod","year":"2019","journal-title":"Virulence"},{"key":"10.1016\/j.virol.2025.110462_bib65","doi-asserted-by":"crossref","first-page":"4029","DOI":"10.3390\/ijms23074029","article-title":"Interactions of liberibacter species with their psyllid vectors: molecular, biological and behavioural mechanisms","volume":"23","author":"Mishra","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.virol.2025.110462_bib66","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1006\/viro.2000.0549","article-title":"The GroEL protein of the whitefly Bemisia tabaci interacts with the coat protein of transmissible and nontransmissible begomoviruses in the yeast two-hybrid system","volume":"276","author":"Morin","year":"2000","journal-title":"Virology"},{"key":"10.1016\/j.virol.2025.110462_bib67","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.immuni.2013.10.020","article-title":"Antiviral autophagy restricts Rift Valley fever virus infection and is conserved from flies to mammals","volume":"40","author":"Moy","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.virol.2025.110462_bib68","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-018-20956-3","article-title":"African ancestry of new world, Bemisia tabaci-whitefly species","volume":"8","author":"Mugerwa","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2025.110462_bib69","doi-asserted-by":"crossref","first-page":"5696","DOI":"10.4049\/jimmunol.1500613","article-title":"Protection of insects against viral infection by apoptosis-dependent phagocytosis","volume":"195","author":"Nainu","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.virol.2025.110462_bib70","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/j.1364-3703.2004.00240.x","article-title":"Transmission of plant viruses by aphid vectors","volume":"5","author":"Ng","year":"2004","journal-title":"Mol. Plant Pathol."},{"key":"10.1016\/j.virol.2025.110462_bib71","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1038\/cdd.2012.27","article-title":"Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response","volume":"19","author":"Pagliarini","year":"2012","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.virol.2025.110462_bib72","doi-asserted-by":"crossref","first-page":"9791","DOI":"10.1128\/JVI.00779-15","article-title":"Replication of Tomato yellow leaf curl virus in its whitefly vector, Bemisia tabaci","volume":"89","author":"Pakkianathan","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2025.110462_bib73","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.virol.2016.12.029","article-title":"Clathrin-mediated endocytosis is involved in Tomato yellow leaf curl virus transport across the midgut barrier of its whitefly vector","volume":"502","author":"Pan","year":"2017","journal-title":"Virology"},{"key":"10.1016\/j.virol.2025.110462_bib74","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.mito.2021.03.008","article-title":"Endoplasmic reticulum & mitochondrial calcium homeostasis: the interplay with viruses","volume":"58","author":"Panda","year":"2021","journal-title":"Mitochondrion"},{"key":"10.1016\/j.virol.2025.110462_bib75","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.aspen.2011.10.005","article-title":"Identification of biotypes and secondary endosymbionts of Bemisia tabaci in Korea and relationships with the occurrence of TYLCV disease","volume":"15","author":"Park","year":"2012","journal-title":"J. Asia Pac. Entomol."},{"key":"10.1016\/j.virol.2025.110462_bib76","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/bs.aivir.2016.02.002","article-title":"Autophagy and mammalian viruses: roles in immune response, viral replication, and beyond","volume":"95","author":"Paul","year":"2016","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.virol.2025.110462_bib77","doi-asserted-by":"crossref","first-page":"287","DOI":"10.3390\/v13020287","article-title":"Transcriptomic responses of the honey bee brain to infection with deformed wing virus","volume":"13","author":"Pizzorno","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.virol.2025.110462_bib78","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.dci.2010.01.006","article-title":"The Toll immune signaling pathway control conserved anti-dengue defenses across diverse Ae. aegypti strains and against multiple dengue virus serotypes","volume":"34","author":"Ramirez","year":"2010","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.virol.2025.110462_bib79","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.629777","article-title":"Arthropods under pressure: stress responses and immunity at the pathogen-vector interface","volume":"11","author":"Rosche","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.virol.2025.110462_bib80","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s13337-014-0217-9","article-title":"Antiviral responses of arthropod vectors: an update on recent advances","volume":"25","author":"R\u00fcckert","year":"2014","journal-title":"Virusdisease"},{"key":"10.1016\/j.virol.2025.110462_bib81","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1099\/0022-1317-78-10-2683","article-title":"Long-term association of Tomato yellow leaf curl virus with its whitefly vector Bemisia tabaci: effect on the insect transmission capacity, longevity and fecundity","volume":"78","author":"Rubinstein","year":"1997","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.virol.2025.110462_bib82","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep30942","article-title":"Tomato yellow leaf curl virus: No evidence for replication in the insect vector Bemisia tabaci","volume":"6","author":"S\u00e1nchez-Campos","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2025.110462_bib83","doi-asserted-by":"crossref","first-page":"37264","DOI":"10.1074\/jbc.M111.259085","article-title":"Role of the endoplasmic reticulum-associated degradation (ERAD) pathway in degradation of hepatitis C virus envelope proteins and production of virus particles","volume":"286","author":"Saeed","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.virol.2025.110462_bib84","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.01301-23","article-title":"The plant pathogenic bacterium Candidatus Liberibacter solanacearum induces calcium-regulated autophagy in midgut cells of its insect vector Bactericera trigonica","volume":"11","author":"Sarkar","year":"2023","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.virol.2025.110462_bib85","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.mrfmmm.2004.06.056","article-title":"ER stress and the unfolded protein response","volume":"569","author":"Schr\u00f6der","year":"2005","journal-title":"Mutat. Res."},{"key":"10.1016\/j.virol.2025.110462_bib86","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cub.2006.10.053","article-title":"Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death","volume":"17","author":"Scott","year":"2007","journal-title":"Curr. Biol."},{"key":"10.1016\/j.virol.2025.110462_bib87","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1007\/s12192-017-0810-0","article-title":"Participation of dengue virus NS4B protein in the modulation of immune effectors dependent on ER stress in insect cells","volume":"22","author":"Sep\u00falveda-Salinas","year":"2017","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.virol.2025.110462_bib88","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3390\/v8070205","article-title":"The whitefly Bemisia tabaci Knottin-1 gene is implicated in regulating the quantity of Tomato yellow leaf curl virus ingested and transmitted by the insect","volume":"8","author":"Shalev","year":"2016","journal-title":"Viruses"},{"key":"10.1016\/j.virol.2025.110462_bib89","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.immuni.2009.02.009","article-title":"Autophagy plays an essential anti-viral role in Drosophila against vesicular stomatitis virus","volume":"30","author":"Shelly","year":"2009","journal-title":"Immunity"},{"key":"10.1016\/j.virol.2025.110462_bib90","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1002\/jcp.25785","article-title":"Crosstalk of autophagy and apoptosis: involvement of the dual role of autophagy under ER stress","volume":"232","author":"Song","year":"2017","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.virol.2025.110462_bib91","doi-asserted-by":"crossref","first-page":"5753","DOI":"10.3390\/ijms24065753","article-title":"Unraveling the role of antimicrobial peptides in insects","volume":"24","author":"St\u0105czek","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.virol.2025.110462_bib92","doi-asserted-by":"crossref","DOI":"10.1038\/srep01367","article-title":"Insect symbiont facilitates vector acquisition, retention, and transmission of plant virus","volume":"3","author":"Su","year":"2013","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2025.110462_bib93","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2023.1136262","article-title":"Effect of silencing Bemisia tabaci TLR3 and TOB1 on fitness and begomovirus transmission","volume":"14","author":"Thesnim","year":"2023","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.virol.2025.110462_bib94","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1513\/pats.200508-089JS","article-title":"Humoral immune defense (antibodies): recent advances","volume":"2","author":"Twigg","year":"2005","journal-title":"Proc. Am. Thorac. Soc."},{"key":"10.1016\/j.virol.2025.110462_bib95","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1080\/15548627.2016.1192749","article-title":"The autophagy pathway participates in resistance to Tomato yellow leaf curl virus infection in whiteflies","volume":"12","author":"Wang","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.virol.2025.110462_bib96","article-title":"A peptidoglycan recognition protein acts in whitefly (Bemisia tabaci) immunity and involves in begomovirus acquisition","volume":"6","author":"Wang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virol.2025.110462_bib97","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1002\/ps.4472","article-title":"RNA interference of an antimicrobial peptide, Btdef, reduces Tomato yellow leaf curl China virus accumulation in the whitefly Bemisia tabaci","volume":"73","author":"Wang","year":"2017","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.virol.2025.110462_bib98","article-title":"Infectious bursal disease virus subverts autophagic vacuoles to promote viral maturation and release","volume":"91","author":"Wang","year":"2017","journal-title":"J. Virol."},{"key":"10.1016\/j.virol.2025.110462_bib99","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1111\/imb.12515","article-title":"The functions of caspase in whitefly Bemisia tabaci apoptosis in response to ultraviolet irradiation","volume":"27","author":"Wang","year":"2018","journal-title":"Insect Mol. Biol."},{"key":"10.1016\/j.virol.2025.110462_bib100","doi-asserted-by":"crossref","DOI":"10.1128\/mSystems.00433-20","article-title":"Apoptosis in a whitefly vector activated by a begomovirus enhances viral transmission","volume":"5","author":"Wang","year":"2020","journal-title":"mSystems"},{"key":"10.1016\/j.virol.2025.110462_bib101","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.56168","article-title":"Apoptotic neurodegeneration in whitefly promotes the spread of TYLCV","volume":"9","author":"Wang","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.virol.2025.110462_bib102","first-page":"1","article-title":"PEBP balances apoptosis and autophagy in whitefly upon arbovirus infection","volume":"13","author":"Wang","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.virol.2025.110462_bib103","doi-asserted-by":"crossref","DOI":"10.1002\/arch.21857","article-title":"Effects of heat stress on virus transmission and virus-mediated apoptosis in whitefly Bemisia tabaci","volume":"110","author":"Wang","year":"2022","journal-title":"Arch. Insect Biochem. Physiol."},{"key":"10.1016\/j.virol.2025.110462_bib104","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006866","article-title":"Intracellular trafficking of begomoviruses in the midgut cells of their insect vector","volume":"14","author":"Xia","year":"2018","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2025.110462_bib105","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004027","article-title":"Complement-related proteins control the flavivirus infection of Aedes aegypti by inducing antimicrobial peptides","volume":"10","author":"Xiao","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2025.110462_bib106","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12864-018-4448-9","article-title":"The invasive MED\/Q Bemisia tabaci genome: a tale of gene loss and gene gain","volume":"19","author":"Xie","year":"2018","journal-title":"BMC Genom."},{"key":"10.1016\/j.virol.2025.110462_bib107","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S0092-8674(01)00611-0","article-title":"XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor","volume":"107","author":"Yoshida","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.virol.2025.110462_bib108","doi-asserted-by":"crossref","first-page":"7257","DOI":"10.1073\/pnas.0409181102","article-title":"The Toll pathway is important for an antiviral response in Drosophila","volume":"102","author":"Zambon","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.virol.2025.110462_bib109","doi-asserted-by":"crossref","first-page":"293","DOI":"10.3389\/fpls.2012.00293","article-title":"Virus-induced ER stress and the unfolded protein response","volume":"3","author":"Zhang","year":"2012","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.virol.2025.110462_bib110","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1011266","article-title":"The JAK-STAT pathway promotes persistent viral infection by activating apoptosis in insect vectors","volume":"19","author":"Zhang","year":"2023","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2025.110462_bib111","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1009053","article-title":"A vector whitefly endocytic receptor facilitates the entry of begomoviruses into its midgut cells via binding to virion capsid proteins","volume":"16","author":"Zhao","year":"2020","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virol.2025.110462_bib112","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.3389\/fimmu.2020.01596","article-title":"Proteomic analyses of whitefly-begomovirus interactions reveal the inhibitory role of tumorous Imaginal discs in viral retention","volume":"11","author":"Zhao","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.virol.2025.110462_bib113","doi-asserted-by":"crossref","first-page":"3835","DOI":"10.3390\/ijms25073835","article-title":"Insect antimicrobial peptides as guardians of immunity and beyond: a review","volume":"25","author":"Zhou","year":"2024","journal-title":"Int. J. Mol. Sci."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682225000741?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682225000741?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T01:58:19Z","timestamp":1762221499000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682225000741"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":113,"alternative-id":["S0042682225000741"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2025.110462","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immunity responses as checkpoints for efficient transmission of begomoviruses by whiteflies","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2025.110462","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110462"}}