{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:27:03Z","timestamp":1777728423286,"version":"3.51.4"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001501","name":"University Grants Commission","doi-asserted-by":"publisher","award":["No.F.4-2\/2006 (BSR)\/BL\/17-18\/0289"],"award-info":[{"award-number":["No.F.4-2\/2006 (BSR)\/BL\/17-18\/0289"]}],"id":[{"id":"10.13039\/501100001501","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009104","name":"Department of Health Research, India","doi-asserted-by":"publisher","award":["ID-2024-1066)-ICM000020"],"award-info":[{"award-number":["ID-2024-1066)-ICM000020"]}],"id":[{"id":"10.13039\/501100009104","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.virol.2026.110827","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T16:40:46Z","timestamp":1771000846000},"page":"110827","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["\u03b2-catenin: A crucial transcriptional activator of KSHV latency genes and small molecule target in primary effusion lymphoma"],"prefix":"10.1016","volume":"618","author":[{"given":"Nilanjana","family":"Das","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koushik","family":"Chakraborty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunny","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nabanita Roy","family":"Chattopadhyay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sibani","family":"Sarkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piyanki","family":"Das","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koustav","family":"Chatterjee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudipa","family":"Mal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4022-0318","authenticated-orcid":false,"given":"Tathagata","family":"Choudhuri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.virol.2026.110827_bib1","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1080\/10428194.2020.1762881","article-title":"Clinicopathologic characteristics and survival of patients with primary effusion lymphoma","volume":"61","author":"Aguilar","year":"2020","journal-title":"Leuk. Lymphoma"},{"issue":"2","key":"10.1016\/j.virol.2026.110827_bib2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/mt.2014.202","article-title":"Exosome-mediated delivery of the intrinsic C-terminus domain of PTEN protects it from proteasomal degradation and ablates tumorigenesis","volume":"23","author":"Ahmed","year":"2015","journal-title":"Mol. Ther."},{"issue":"22","key":"10.1016\/j.virol.2026.110827_bib3","doi-asserted-by":"crossref","first-page":"3371","DOI":"10.1038\/sj.onc.1206407","article-title":"Kaposi's sarcoma-associated herpesvirus encoded vFLIP induces cellular IL-6 expression: the role of the NF-\u03baB and JNK\/AP1 pathways","volume":"22","author":"An","year":"2003","journal-title":"Oncogene"},{"issue":"1","key":"10.1016\/j.virol.2026.110827_bib4","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1186\/s12885-020-07537-2","article-title":"The majority of \u03b2-catenin mutations in colorectal cancer is homozygous","volume":"20","author":"Arnold","year":"2020","journal-title":"BMC Cancer"},{"issue":"7","key":"10.1016\/j.virol.2026.110827_bib5","doi-asserted-by":"crossref","first-page":"3250","DOI":"10.1128\/JVI.75.7.3250-3258.2001","article-title":"Kaposi's sarcoma-associated Herpesvirus latency-associated nuclear antigen 1 mediates episome persistence through cis -Acting Terminal Repeat (TR) sequence and specifically binds TR DNA","volume":"75","author":"Ballestas","year":"2001","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.virol.2026.110827_bib6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s40588-018-0102-1","article-title":"Transcriptional and post-transcriptional regulation of viral gene expression in the gamma-herpesvirus kaposi's sarcoma-associated herpesvirus","volume":"5","author":"Butnaru","year":"2018","journal-title":"Curr Clin Micro Rpt"},{"issue":"1","key":"10.1016\/j.virol.2026.110827_bib7","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s13027-020-00317-4","article-title":"The interplay between EBV and KSHV viral products and NF-\u03baB pathway in oncogenesis","volume":"15","author":"Charostad","year":"2020","journal-title":"Infect. Agents Cancer"},{"issue":"11","key":"10.1016\/j.virol.2026.110827_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005255","article-title":"Kaposi's sarcoma-associated herpesvirus (KSHV) induces the oncogenic miR-17-92 cluster and down-regulates TGF-\u03b2 signaling","volume":"11","author":"Choi","year":"2015","journal-title":"PLoS Pathog."},{"issue":"6","key":"10.1016\/j.virol.2026.110827_bib9","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.cell.2012.05.012","article-title":"Wnt\/\u03b2-catenin signaling and disease","volume":"149","author":"Clevers","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.virol.2026.110827_bib10","unstructured":"CTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment | Nat. Commun. Accessed August 29, 2025. https:\/\/www.nature.com\/articles\/s41467-024-49684-1."},{"key":"10.1016\/j.virol.2026.110827_bib11","unstructured":"CTCF regulates kaposi's sarcoma-associated Herpesvirus latency transcription by Nucleosome displacement and RNA polymerase programming | J. Virol. Accessed August 29, 2025. https:\/\/journals.asm.org\/doi\/full\/10.1128\/jvi.02283-12."},{"key":"10.1016\/j.virol.2026.110827_bib12","series-title":"The Role of Host Cell Factors in the Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus from Latency","author":"Dalton-Griffin","year":"2010"},{"issue":"6","key":"10.1016\/j.virol.2026.110827_bib13","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.cellsig.2016.03.007","article-title":"Estrogen receptor alpha transcriptionally activates casein kinase 2 alpha: a pivotal regulator of promyelocytic leukaemia protein (PML) and AKT in oncogenesis","volume":"28","author":"Das","year":"2016","journal-title":"Cell. Signal."},{"issue":"6","key":"10.1016\/j.virol.2026.110827_bib14","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.cellsig.2016.03.007","article-title":"Estrogen receptor alpha transcriptionally activates casein kinase 2 alpha: a pivotal regulator of promyelocytic leukaemia protein (PML) and AKT in oncogenesis","volume":"28","author":"Das","year":"2016","journal-title":"Cell. Signal."},{"key":"10.1016\/j.virol.2026.110827_bib15","unstructured":"DEAD-box protein p68 is regulated by \u03b2-catenin\/transcription factor 4 to maintain a positive feedback loop in control of breast cancer progression | Breast Cancer Res. Accessed August 29, 2025. https:\/\/link.springer.com\/article\/10.1186\/s13058-014-0496-5."},{"issue":"11","key":"10.1016\/j.virol.2026.110827_bib16","article-title":"Combination of arsenic and Interferon-\u03b1 inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion lymphomas","volume":"8","author":"El","year":"2013","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.virol.2026.110827_bib18","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/nm829","article-title":"A novel viral mechanism for dysregulation of \u03b2-catenin in Kaposi's sarcoma\u2013associated herpesvirus latency","volume":"9","author":"Fujimuro","year":"2003","journal-title":"Nat. Med."},{"issue":"3","key":"10.1016\/j.virol.2026.110827_bib19","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/nm829","article-title":"A novel viral mechanism for dysregulation of \u03b2-catenin in Kaposi's sarcoma\u2013associated herpesvirus latency","volume":"9","author":"Fujimuro","year":"2003","journal-title":"Nat. Med."},{"issue":"3","key":"10.1016\/j.virol.2026.110827_bib20","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/nm829","article-title":"A novel viral mechanism for dysregulation of \u03b2-catenin in Kaposi's sarcoma\u2013associated herpesvirus latency","volume":"9","author":"Fujimuro","year":"2003","journal-title":"Nat. Med."},{"issue":"16","key":"10.1016\/j.virol.2026.110827_bib21","doi-asserted-by":"crossref","first-page":"10429","DOI":"10.1128\/JVI.79.16.10429-10441.2005","article-title":"Regulation of the interaction between Glycogen synthase kinase 3 and the kaposi's sarcoma-associated Herpesvirus latency-associated nuclear antigen","volume":"79","author":"Fujimuro","year":"2005","journal-title":"J. Virol."},{"issue":"16","key":"10.1016\/j.virol.2026.110827_bib22","doi-asserted-by":"crossref","first-page":"10429","DOI":"10.1128\/JVI.79.16.10429-10441.2005","article-title":"Regulation of the interaction between Glycogen Synthase Kinase 3 and the kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen","volume":"79","author":"Fujimuro","year":"2005","journal-title":"J. Virol."},{"issue":"49","key":"10.1016\/j.virol.2026.110827_bib23","doi-asserted-by":"crossref","first-page":"7290","DOI":"10.1038\/sj.onc.1208894","article-title":"PI3K-AKT pathway negatively controls EGFR-dependent DNA-binding activity of Stat3 in glioblastoma multiforme cells","volume":"24","author":"Ghosh","year":"2005","journal-title":"Oncogene"},{"key":"10.1016\/j.virol.2026.110827_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.123018","article-title":"GBM immunotherapy: exploring molecular and clinical frontiers","author":"Ghosh","year":"2024","journal-title":"Life Sci."},{"key":"10.1016\/j.virol.2026.110827_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbagrm.2025.195120","article-title":"Identification of a novel p65-p68 loop: a crucial determinant for p68 gene regulation in oncogenesis","author":"Ghosh","year":"2025","journal-title":"Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms"},{"key":"10.1016\/j.virol.2026.110827_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbagrm.2025.195120","article-title":"Identification of a novel p65-p68 loop: a crucial determinant for p68 gene regulation in oncogenesis","author":"Ghosh","year":"2025","journal-title":"Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms"},{"issue":"1","key":"10.1016\/j.virol.2026.110827_bib27","doi-asserted-by":"crossref","DOI":"10.3402\/jom.v5i0.22766","article-title":"Herpesviruses: latency and reactivation \u2013 viral strategies and host response","volume":"5","author":"Grinde","year":"2013","journal-title":"J. Oral Microbiol."},{"issue":"4","key":"10.1016\/j.virol.2026.110827_bib28","doi-asserted-by":"crossref","first-page":"878","DOI":"10.3390\/cancers13040878","article-title":"Primary effusion lymphoma: a clinicopathological study of 70 cases","volume":"13","author":"Hu","year":"2021","journal-title":"Cancers"},{"issue":"5-6","key":"10.1016\/j.virol.2026.110827_bib29","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1101\/gad.352235.124","article-title":"Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain","volume":"39","author":"Huang","year":"2025","journal-title":"Genes Dev."},{"issue":"3","key":"10.1016\/j.virol.2026.110827_bib30","doi-asserted-by":"crossref","first-page":"46","DOI":"10.3892\/or.2022.8257","article-title":"A pyridinium-type fullerene derivative suppresses primary effusion lymphoma cell viability via the downregulation of the Wnt signaling pathway through the destabilization of \u03b2-catenin","volume":"47","author":"Kadota","year":"2022","journal-title":"Oncol. Rep."},{"issue":"8","key":"10.1016\/j.virol.2026.110827_bib31","doi-asserted-by":"crossref","first-page":"3295","DOI":"10.1182\/blood-2005-07-2730","article-title":"NF-\u03baB is essential for the progression of KSHV-and EBV-infected lymphomas in vivo","volume":"107","author":"Keller","year":"2006","journal-title":"Blood"},{"issue":"6","key":"10.1016\/j.virol.2026.110827_bib32","doi-asserted-by":"crossref","first-page":"e166","DOI":"10.1038\/emm.2015.33","article-title":"CTCF as a multifunctional protein in genome regulation and gene expression","volume":"47","author":"Kim","year":"2015","journal-title":"Exp. Mol. Med."},{"issue":"6","key":"10.1016\/j.virol.2026.110827_bib33","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/j.gendis.2021.08.003","article-title":"Chaperone-assisted E3 ligase CHIP: a double agent in cancer","volume":"9","author":"Kumar","year":"2022","journal-title":"Genes Dis."},{"issue":"4","key":"10.1016\/j.virol.2026.110827_bib34","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/j.gendis.2022.07.024","article-title":"Targeting PD-1\/PD-L1 in cancer immunotherapy: an effective strategy for treatment of triple-negative breast cancer (TNBC) patients","volume":"10","author":"Kumar","year":"2023","journal-title":"Genes Dis."},{"key":"10.1016\/j.virol.2026.110827_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2024.119827","article-title":"E3 ubiquitin ligases and deubiquitinases in colorectal cancer: emerging molecular insights and therapeutic opportunities","author":"Kumar","year":"2024","journal-title":"Biochim. Biophys. Acta Mol. Cell Res."},{"key":"10.1016\/j.virol.2026.110827_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2025.120049","article-title":"CHIP modulates Wnt\/\u03b2-catenin signalling in colorectal cancer through proteasomal degradation of DDX17","author":"Kumar","year":"2025","journal-title":"Biochim. Biophys. Acta Mol. Cell Res."},{"key":"10.1016\/j.virol.2026.110827_bib37","first-page":"1","article-title":"Phytochemical profiling of Andrographis beddomei C.B. Clarke using UHPLC-ORBITRAP-MS\/MS approach and assessment of cytotoxicity in cisplatin-resistant ovarian cancer","author":"Kumar","year":"2025","journal-title":"Nat. Prod. Res."},{"issue":"13","key":"10.1016\/j.virol.2026.110827_bib38","doi-asserted-by":"crossref","first-page":"6411","DOI":"10.1128\/JVI.00239-06","article-title":"Intracellular activated Notch1 is critical for proliferation of Kaposi's sarcoma-associated herpesvirus-associated B-Lymphoma cell lines in vitro","volume":"80","author":"Lan","year":"2006","journal-title":"J. Virol."},{"issue":"19","key":"10.1016\/j.virol.2026.110827_bib39","doi-asserted-by":"crossref","first-page":"10451","DOI":"10.1128\/JVI.00804-07","article-title":"The kaposi's sarcoma-associated herpesvirus LANA protein stabilizes and activates c-Myc","volume":"81","author":"Liu","year":"2007","journal-title":"J. Virol."},{"issue":"13","key":"10.1016\/j.virol.2026.110827_bib40","doi-asserted-by":"crossref","first-page":"7203","DOI":"10.3390\/ijms23137203","article-title":"Human gammaherpesvirus 8 oncogenes associated with Kaposi's sarcoma","volume":"23","author":"Lopes","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.virol.2026.110827_bib41","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.devcel.2009.06.016","article-title":"Wnt\/\u03b2-catenin signaling: components, mechanisms, and diseases","volume":"17","author":"MacDonald","year":"2009","journal-title":"Dev. Cell"},{"issue":"1","key":"10.1016\/j.virol.2026.110827_bib42","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.devcel.2009.06.016","article-title":"Wnt\/\u03b2-Catenin signaling: components, mechanisms, and diseases","volume":"17","author":"MacDonald","year":"2009","journal-title":"Dev. Cell"},{"issue":"9","key":"10.1016\/j.virol.2026.110827_bib43","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1007\/s10495-017-1391-1","article-title":"Multi-targeted therapy of everolimus in Kaposi's sarcoma associated herpes virus infected primary effusion lymphoma","volume":"22","author":"Mohanty","year":"2017","journal-title":"Apoptosis"},{"issue":"9","key":"10.1016\/j.virol.2026.110827_bib44","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1007\/s10495-017-1391-1","article-title":"Multi-targeted therapy of everolimus in Kaposi's sarcoma associated herpes virus infected primary effusion lymphoma","volume":"22","author":"Mohanty","year":"2017","journal-title":"Apoptosis"},{"issue":"5307","key":"10.1016\/j.virol.2026.110827_bib45","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1126\/science.275.5307.1787","article-title":"Activation of \u03b2-Catenin-Tcf signaling in Colon cancer by mutations in \u03b2-Catenin or APC","volume":"275","author":"Morin","year":"1997","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.virol.2026.110827_bib46","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1128\/JVI.06266-11","article-title":"Role of \u03b2-Catenin and TCF\/LEF family members in transcriptional activity of HIV in astrocytes","volume":"86","author":"Narasipura","year":"2012","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virol.2026.110827_bib47","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s13027-016-0086-5","article-title":"Establishing and characterizing a new primary effusion lymphoma cell line harboring Kaposi's sarcoma\u2013associated herpesvirus","volume":"11","author":"Osawa","year":"2016","journal-title":"Infect. Agents Cancer"},{"issue":"18","key":"10.1016\/j.virol.2026.110827_bib48","doi-asserted-by":"crossref","first-page":"19153","DOI":"10.1021\/acs.jmedchem.5c01229","article-title":"Isoquinolinone\u2013naphthoquinone hybrids as potent PARP-1 inhibitors induce apoptosis in glioma via DNA damage and ROS generation","volume":"68","author":"Pathi","year":"2025","journal-title":"J. Med. Chem."},{"issue":"7","key":"10.1016\/j.virol.2026.110827_bib49","doi-asserted-by":"crossref","first-page":"3574","DOI":"10.3390\/v7072791","article-title":"Targeting CTCF to control virus gene expression: a common theme amongst diverse DNA viruses","volume":"7","author":"Pentland","year":"2015","journal-title":"Viruses"},{"issue":"1","key":"10.1016\/j.virol.2026.110827_bib50","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1472-6807-8-38","article-title":"Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB\/DNA interactions and inhibitory effects on IL-8 gene expression","volume":"8","author":"Piccagli","year":"2008","journal-title":"BMC Struct. Biol."},{"issue":"12","key":"10.1016\/j.virol.2026.110827_bib51","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1038\/onc.2009.460","article-title":"Kaposi's sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a","volume":"29","author":"Punj","year":"2010","journal-title":"Oncogene"},{"issue":"11","key":"10.1016\/j.virol.2026.110827_bib52","doi-asserted-by":"crossref","DOI":"10.1002\/jmv.70718","article-title":"Recent advances in development of Kaposi's sarcoma\u2010associated herpesvirus\u2010latency\u2010associated nuclear antigen targeted therapies","volume":"97","author":"Qin","year":"2025","journal-title":"J. Med. Virol."},{"issue":"47","key":"10.1016\/j.virol.2026.110827_bib53","doi-asserted-by":"crossref","first-page":"5843","DOI":"10.1038\/onc.2015.42","article-title":"The DEAD box protein p68: a crucial regulator of AKT\/FOXO3a signaling axis in oncogenesis","volume":"34","author":"Sarkar","year":"2015","journal-title":"Oncogene"},{"key":"10.1016\/j.virol.2026.110827_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2024.124697","article-title":"Glioma nanotherapy: unleashing the synergy of dual-loaded DIM and TMZ","volume":"665","author":"Sarkar","year":"2024","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.virol.2026.110827_bib55","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.mce.2017.02.008","article-title":"Revisiting the role of Wnt\/\u03b2-catenin signaling in prostate cancer","volume":"462","author":"Schneider","year":"2018","journal-title":"Mol. Cell. Endocrinol."},{"issue":"1732","key":"10.1016\/j.virol.2026.110827_bib56","doi-asserted-by":"crossref","DOI":"10.1098\/rstb.2016.0271","article-title":"Epstein\u2013Barr virus-associated lymphomas","volume":"372","author":"Shannon-Lowe","year":"2017","journal-title":"Philos. Trans. R. Soc. B"},{"issue":"12","key":"10.1016\/j.virol.2026.110827_bib58","doi-asserted-by":"crossref","first-page":"7362","DOI":"10.1074\/jbc.C115.637918","article-title":"Oncovirus Kaposi sarcoma herpesvirus (KSHV) represses tumor suppressor PDLIM2 to persistently activate nuclear factor \u03baB (NF-\u03baB) and STAT3 transcription factors for tumorigenesis and tumor maintenance","volume":"290","author":"Sun","year":"2015","journal-title":"J. Biol. Chem."},{"issue":"12","key":"10.1016\/j.virol.2026.110827_bib59","doi-asserted-by":"crossref","first-page":"4961","DOI":"10.3390\/v6124961","article-title":"KSHV LANA--the master regulator of KSHV latency","volume":"6","author":"Uppal","year":"2014","journal-title":"Viruses"},{"issue":"5","key":"10.1016\/j.virol.2026.110827_bib60","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1128\/JVI.80.5.2243-2256.2006","article-title":"Latency-associated nuclear antigen (LANA) of Kaposi's sarcoma-associated herpesvirus interacts with origin recognition complexes at the LANA binding sequence within the terminal repeats","volume":"80","author":"Verma","year":"2006","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.virol.2026.110827_bib61","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s40659-020-00301-7","article-title":"\u03b2-Catenin: oncogenic role and therapeutic target in cervical cancer","volume":"53","author":"Wang","year":"2020","journal-title":"Biol. Res."},{"issue":"1","key":"10.1016\/j.virol.2026.110827_bib62","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s40659-020-00301-7","article-title":"\u03b2-Catenin: oncogenic role and therapeutic target in cervical cancer","volume":"53","author":"Wang","year":"2020","journal-title":"Biol. Res."},{"issue":"S1","key":"10.1016\/j.virol.2026.110827_bib63","doi-asserted-by":"crossref","DOI":"10.1186\/1477-5956-10-S1-S17","article-title":"High performance transcription factor-DNA docking with GPU computing","volume":"10","author":"Wu","year":"2012","journal-title":"Proteome Sci."},{"issue":"W1","key":"10.1016\/j.virol.2026.110827_bib64","doi-asserted-by":"crossref","first-page":"W365","DOI":"10.1093\/nar\/gkx407","article-title":"HDOCK: a web server for protein\u2013protein and protein\u2013DNA\/RNA docking based on a hybrid strategy","volume":"45","author":"Yan","year":"2017","journal-title":"Nucleic Acids Res."},{"issue":"4","key":"10.1016\/j.virol.2026.110827_bib65","doi-asserted-by":"crossref","first-page":"144","DOI":"10.5501\/wjv.v5.i4.144","article-title":"Regulation of Wnt\/\u03b2-catenin signaling by herpesviruses","volume":"5","author":"Zwezdaryk","year":"2016","journal-title":"World J. Virol."},{"issue":"4","key":"10.1016\/j.virol.2026.110827_bib66","doi-asserted-by":"crossref","first-page":"144","DOI":"10.5501\/wjv.v5.i4.144","article-title":"Regulation of Wnt\/\u03b2-catenin signaling by herpesviruses","volume":"5","author":"Zwezdaryk","year":"2016","journal-title":"World J. Virol."},{"key":"10.1016\/j.virol.2026.110827_bib67","unstructured":"2,2\u2032-Diphenyl-3,3\u2032-Diindolylmethane: a potent compound induces apoptosis in breast cancer cells by inhibiting EGFR pathway | PLoS One. Accessed August 29, 2025. https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0059798."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682226000425?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682226000425?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:52:02Z","timestamp":1777459922000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682226000425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":65,"alternative-id":["S0042682226000425"],"URL":"https:\/\/doi.org\/10.1016\/j.virol.2026.110827","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"\u03b2-catenin: A crucial transcriptional activator of KSHV latency genes and small molecule target in primary effusion lymphoma","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virol.2026.110827","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110827"}}