{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T12:34:44Z","timestamp":1793450084167,"version":"4.5.0"},"reference-count":66,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008766","name":"Fujian Agriculture and Forestry University","doi-asserted-by":"publisher","award":["xjq202018"],"award-info":[{"award-number":["xjq202018"]}],"id":[{"id":"10.13039\/501100008766","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2022J05033"],"award-info":[{"award-number":["2022J05033"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFD1800205"],"award-info":[{"award-number":["2021YFD1800205"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019939","name":"General Administration of Customs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019939","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virologica Sinica"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.virs.2026.09.003","type":"journal-article","created":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T14:57:05Z","timestamp":1788620225000},"page":"1106-1120","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["A HiBiT-Tagged influenza A virus reporter system reveals cytokine-inhibitory micropeptide 53 as a modulator of viral infection and immunopathology"],"prefix":"10.1016","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3087-6356","authenticated-orcid":false,"given":"Shujie","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sha","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conghui","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjun","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiacheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoxi","family":"Qiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanhuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peilin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.virs.2026.09.003_bib1","first-page":"73","article-title":"The NS1 protein: a multitasking virulence factor","volume":"386","author":"Ayllon","year":"2015","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.virs.2026.09.003_bib2","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1073\/pnas.031575198","article-title":"Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes","volume":"98","author":"Basler","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.virs.2026.09.003_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/v8070179","article-title":"Replication-competent influenza A viruses expressing reporter genes","volume":"8","author":"Breen","year":"2016","journal-title":"Viruses"},{"key":"10.1016\/j.virs.2026.09.003_bib4","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/978-1-0716-3533-9_4","article-title":"Use of reverse genetics for the generation of recombinant influenza viruses carrying nanoluciferase","volume":"2733","author":"Caceres","year":"2024","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.virs.2026.09.003_bib5","doi-asserted-by":"crossref","DOI":"10.1186\/s12950-025-00454-w","article-title":"Unveiling the anti-inflammatory potential of RF16, an interleukin 8-derived therapeutic peptide in macrophages","volume":"22","author":"Chang","year":"2025","journal-title":"J. Inflamm."},{"key":"10.1016\/j.virs.2026.09.003_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.crimmu.2023.100062","article-title":"Interplay of host and viral factors in inflammatory pathway mediated cytokine storm during RNA virus infection","volume":"4","author":"Chaudhary","year":"2023","journal-title":"Curr Res Immunol"},{"key":"10.1016\/j.virs.2026.09.003_bib7","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/S0140-6736(14)60111-2","article-title":"Clinical and epidemiological characteristics of a fatal case of Avian influenza A H10N8 virus infection: a descriptive study","volume":"383","author":"Chen","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.virs.2026.09.003_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1012461","article-title":"A small protein encoded by PCBP1-AS1 is identified as a key regulator of influenza virus replication via enhancing autophagy","volume":"20","author":"Chi","year":"2024","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.virs.2026.09.003_bib9","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/9296457","article-title":"The effect of Oseltamivir on the disease progression of lethal influenza A virus infection: Plasma cytokine and miRNA responses in a mouse model","volume":"2016","author":"Chockalingam","year":"2016","journal-title":"Dis. Markers"},{"key":"10.1016\/j.virs.2026.09.003_bib10","doi-asserted-by":"crossref","first-page":"7097","DOI":"10.1093\/nar\/gkac512","article-title":"TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway","volume":"50","author":"Choudhury","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.virs.2026.09.003_bib11","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/nri3344","article-title":"The broad-spectrum antiviral functions of IFIT and IFITM proteins","volume":"13","author":"Diamond","year":"2013","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.virs.2026.09.003_bib12","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1021\/acschembio.5b00753","article-title":"NanoLuc complementation reporter optimized for accurate measurement of protein interactions in cells","volume":"11","author":"Dixon","year":"2016","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.virs.2026.09.003_bib13","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1128\/JVI.75.1.408-419.2001","article-title":"Interaction of the influenza virus nucleoprotein with the cellular CRM1-mediated nuclear export pathway","volume":"75","author":"Elton","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.virs.2026.09.003_bib14","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1056\/NEJMra2026131","article-title":"Cytokine storm","volume":"383","author":"Fajgenbaum","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.virs.2026.09.003_bib15","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms7600","article-title":"Multi-spectral fluorescent reporter influenza viruses (Color-flu) as powerful tools for in vivo studies","volume":"6","author":"Fukuyama","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.virs.2026.09.003_bib16","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1038\/s41586-024-08254-7","article-title":"A human isolate of bovine H5N1 is transmissible and lethal in animal models","volume":"636","author":"Gu","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.virs.2026.09.003_bib17","doi-asserted-by":"crossref","DOI":"10.3390\/v13071362","article-title":"The mechanism behind influenza virus cytokine storm","volume":"13","author":"Gu","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.virs.2026.09.003_bib18","first-page":"636","article-title":"SmProt: a database of small proteins encoded by annotated coding and non-coding RNA loci","volume":"19","author":"Hao","year":"2018","journal-title":"Briefings Bioinf."},{"key":"10.1016\/j.virs.2026.09.003_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.antiviral.2020.104968","article-title":"Development and characterization of recombinant tick-borne encephalitis virus expressing mCherry reporter protein: a new tool for high-throughput screening of antiviral compounds, and neutralizing antibody assays","volume":"185","author":"Haviernik","year":"2021","journal-title":"Antivir. Res."},{"key":"10.1016\/j.virs.2026.09.003_bib20","doi-asserted-by":"crossref","DOI":"10.1080\/22221751.2024.2343912","article-title":"Evolution of H7N9 highly pathogenic avian influenza virus in the context of vaccination","volume":"13","author":"Hou","year":"2024","journal-title":"Emerg. Microb. Infect."},{"key":"10.1016\/j.virs.2026.09.003_bib21","series-title":"HTS Assay Validation","author":"Iversen","year":"2012"},{"key":"10.1016\/j.virs.2026.09.003_bib22","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/nri3665","article-title":"Innate immunity to influenza virus infection","volume":"14","author":"Iwasaki","year":"2014","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.virs.2026.09.003_bib23","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1128\/JVI.01698-07","article-title":"A single-amino-acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice","volume":"82","author":"Jiao","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.virs.2026.09.003_bib24","doi-asserted-by":"crossref","first-page":"3942","DOI":"10.1128\/JVI.03109-13","article-title":"Activation of the interferon induction cascade by influenza a viruses requires viral RNA synthesis and nuclear export","volume":"88","author":"Killip","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.virs.2026.09.003_bib25","article-title":"High cleavage efficiency of a 2A peptide derived from porcine teschovirus-1 in human cell lines, zebrafish and mice","volume":"6","author":"Kim","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.virs.2026.09.003_bib26","doi-asserted-by":"crossref","DOI":"10.1038\/srep11233","article-title":"A live attenuated vaccine prevents replication and transmission of H7N9 virus in mammals","volume":"5","author":"Kong","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.virs.2026.09.003_bib27","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.ymthe.2023.11.002","article-title":"Intracellular delivery of nuclear localization sequence peptide mitigates COVID-19 by inhibiting nuclear transport of inflammation-associated transcription factors","volume":"32","author":"Lee","year":"2024","journal-title":"Mol. Ther."},{"key":"10.1016\/j.virs.2026.09.003_bib28","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.antiviral.2019.05.013","article-title":"Development of a rapid antiviral screening assay based on eGFP reporter virus of Mayaro virus","volume":"168","author":"Li","year":"2019","journal-title":"Antivir. Res."},{"key":"10.1016\/j.virs.2026.09.003_bib29","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.gpb.2021.09.002","article-title":"SmProt: a reliable repository with comprehensive annotation of small proteins identified from ribosome profiling","volume":"19","author":"Li","year":"2021","journal-title":"Genom. Proteom. Bioinform."},{"key":"10.1016\/j.virs.2026.09.003_bib30","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2020.02100","article-title":"Development of HiBiT-Tagged recombinant infectious bronchitis coronavirus for efficient in vitro and in vivo viral quantification","volume":"11","author":"Liang","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.virs.2026.09.003_bib31","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/cmi.2015.74","article-title":"The cytokine storm of severe influenza and development of immunomodulatory therapy","volume":"13","author":"Liu","year":"2016","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.virs.2026.09.003_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.01843","article-title":"Influenza virus-induced robust expression of SOCS3 contributes to excessive production of IL-6","volume":"10","author":"Liu","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.virs.2026.09.003_bib33","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.01530-19","article-title":"Amino acid mutations A286V and T437M in the nucleoprotein attenuate H7N9 viruses in mice","volume":"94","author":"Ma","year":"2020","journal-title":"J. Virol."},{"key":"10.1016\/j.virs.2026.09.003_bib34","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1093\/jmcb\/mjaa047","article-title":"Rapid quantitative screening assay for SARS-CoV-2 neutralizing antibodies using HiBiT-tagged virus-like particles","volume":"12","author":"Miyakawa","year":"2020","journal-title":"J. Mol. Cell Biol."},{"key":"10.1016\/j.virs.2026.09.003_bib35","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.00508-23","article-title":"Development of a HiBiT-tagged reporter hepatitis E virus and its utility as an antiviral drug screening platform","volume":"97","author":"Nagashima","year":"2023","journal-title":"J. Virol."},{"key":"10.1016\/j.virs.2026.09.003_bib36","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1093\/infdis\/jiae353","article-title":"Establishment of a hepatitis B virus reporter system harboring a HiBiT-tag in the PreS2 region","volume":"231","author":"Nakaya","year":"2024","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.virs.2026.09.003_bib37","doi-asserted-by":"crossref","first-page":"9345","DOI":"10.1073\/pnas.96.16.9345","article-title":"Generation of influenza A viruses entirely from cloned cDNAs","volume":"96","author":"Neumann","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.virs.2026.09.003_bib38","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aaz2059","article-title":"A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation","volume":"6","author":"Niu","year":"2020","journal-title":"Sci. Adv."},{"key":"10.1016\/j.virs.2026.09.003_bib39","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/1348-0421.13122","article-title":"Rapid quantitative detection system for measles virus-neutralizing antibodies using HiBiT-tagged virus-like particles","volume":"68","author":"Okura","year":"2024","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.virs.2026.09.003_bib40","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1038\/s41586-024-08054-z","article-title":"The global H5N1 influenza panzootic in mammals","volume":"637","author":"Peacock","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.virs.2026.09.003_bib41","doi-asserted-by":"crossref","DOI":"10.3390\/v15101989","article-title":"Three distinct reporter systems of hepatitis E virus and their utility as drug screening platforms","volume":"15","author":"Primadharsini","year":"2023","journal-title":"Viruses"},{"key":"10.1016\/j.virs.2026.09.003_bib42","doi-asserted-by":"crossref","DOI":"10.1186\/s12896-017-0367-0","article-title":"Evaluation of Gaussia luciferase and foot-and-mouth disease virus 2A translational interrupter chimeras as polycistronic reporters for transgene expression","volume":"17","author":"Puckette","year":"2017","journal-title":"BMC Biotechnol."},{"key":"10.1016\/j.virs.2026.09.003_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e31905","article-title":"Highly sensitive and quantitative HiBiT-tagged Nipah virus-like particles: a platform for rapid antibody neutralization studies","volume":"10","author":"Rajan","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.virs.2026.09.003_bib44","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-021-22964-w","article-title":"Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models","volume":"12","author":"Saito","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.virs.2026.09.003_bib45","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1021\/acschembio.7b00549","article-title":"CRISPR-Mediated tagging of endogenous proteins with a luminescent peptide","volume":"13","author":"Schwinn","year":"2018","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.virs.2026.09.003_bib46","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1038\/cr.2017.129","article-title":"H7N9 virulent mutants detected in chickens in China pose an increased threat to humans","volume":"27","author":"Shi","year":"2017","journal-title":"Cell Res."},{"key":"10.1016\/j.virs.2026.09.003_bib47","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.virs.2023.06.007","article-title":"A high throughput antiviral screening platform for alphaviruses based on Semliki Forest virus expressing eGFP reporter gene","volume":"38","author":"Shi","year":"2023","journal-title":"Virol. Sin."},{"key":"10.1016\/j.virs.2026.09.003_bib48","article-title":"Current perspectives on functional involvement of micropeptides in virus-host interactions","volume":"26","author":"Sun","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.virs.2026.09.003_bib49","doi-asserted-by":"crossref","first-page":"4074","DOI":"10.1016\/j.cell.2023.08.011","article-title":"Airborne transmission of human-isolated avian H3N8 influenza virus between ferrets","volume":"186","author":"Sun","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.virs.2026.09.003_bib50","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1038\/s41590-025-02280-x","article-title":"Delaying pyroptosis with an AI-screened gasdermin D pore blocker mitigates inflammatory response","volume":"26","author":"Sun","year":"2025","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.virs.2026.09.003_bib51","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1038\/s41564-018-0240-5","article-title":"Mini viral RNAs act as innate immune agonists during influenza virus infection","volume":"3","author":"Te Velthuis","year":"2018","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.virs.2026.09.003_bib52","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jim.2014.03.023","article-title":"Animal models for influenza virus pathogenesis, transmission, and immunology","volume":"410","author":"Thangavel","year":"2014","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.virs.2026.09.003_bib53","first-page":"e01707","article-title":"The G protein-coupled receptor FFAR2 promotes internalization during influenza A virus entry","volume":"94","author":"Wang","year":"2020","journal-title":"J. Virol."},{"key":"10.1016\/j.virs.2026.09.003_bib54","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.scib.2018.01.002","article-title":"Generation and application of replication-competent Venus-expressing H5N1, H7N9, and H9N2 influenza A viruses","volume":"63","author":"Wang","year":"2018","journal-title":"Sci Bull (Beijing)"},{"key":"10.1016\/j.virs.2026.09.003_bib55","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007189","article-title":"Metabotropic Glutamate Receptor Subtype 2 is a Cellular Receptor for Rabies Virus","volume":"vol. 14","author":"Wang","year":"2018","journal-title":"PLoS pathogens"},{"key":"10.1016\/j.virs.2026.09.003_bib56","doi-asserted-by":"crossref","DOI":"10.1038\/s41426-018-0154-6","article-title":"A live attenuated vaccine prevents replication and transmission of H7N9 highly pathogenic influenza viruses in mammals","volume":"7","author":"Yang","year":"2018","journal-title":"Emerg. Microb. Infect."},{"key":"10.1016\/j.virs.2026.09.003_bib57","article-title":"Development of an HiBiT-tagged reporter H3N2 influenza A virus and its utility as an antiviral screening platform","volume":"95","author":"Zhang","year":"2023","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.virs.2026.09.003_bib58","doi-asserted-by":"crossref","DOI":"10.1186\/s13567-025-01484-1","article-title":"Emergence of a novel reassortant H3N3 avian influenza virus with enhanced pathogenicity and transmissibility in chickens in China","volume":"56","author":"Zhang","year":"2025","journal-title":"Vet Res"},{"key":"10.1016\/j.virs.2026.09.003_bib59","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1177\/108705719900400206","article-title":"A simple statistical parameter for use in evaluation and validation of high throughput screening assays","volume":"4","author":"Zhang","year":"1999","journal-title":"J. Biomol. Screen"},{"key":"10.1016\/j.virs.2026.09.003_bib60","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1007\/s12250-020-00316-0","article-title":"Generation of a stable GFP-reporter zika virus system for high-throughput screening of zika virus inhibitors","volume":"36","author":"Zhang","year":"2021","journal-title":"Virol. Sin."},{"key":"10.1016\/j.virs.2026.09.003_bib61","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1126\/science.1240532","article-title":"H7N9 influenza viruses are transmissible in ferrets by respiratory droplet","volume":"341","author":"Zhang","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.virs.2026.09.003_bib62","doi-asserted-by":"crossref","DOI":"10.1186\/s12943-025-02278-x","article-title":"Small open reading frame-encoded microproteins in cancer: identification, biological functions and clinical significance","volume":"24","author":"Zhang","year":"2025","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.virs.2026.09.003_bib63","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1126\/science.1229455","article-title":"H5N1 hybrid viruses bearing 2009\/H1N1 virus genes transmit in Guinea pigs by respiratory droplet","volume":"340","author":"Zhang","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.virs.2026.09.003_bib64","article-title":"Characteristics of the first domestic duck-origin H12N8 avian influenza virus in China","volume":"26","author":"Zhao","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.virs.2026.09.003_bib65","article-title":"Proteomic analysis of differentially expressed proteins in A549 cells infected with H9N2 avian influenza virus","volume":"26","author":"Zhao","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.virs.2026.09.003_bib66","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1016\/S1473-3099(16)00078-5","article-title":"Host-directed therapies for infectious diseases: current status, recent progress, and future prospects","volume":"16","author":"Zumla","year":"2016","journal-title":"Lancet Infect. Dis."}],"container-title":["Virologica Sinica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1995820X26001641?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1995820X26001641?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T12:19:27Z","timestamp":1793449167000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1995820X26001641"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":66,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S1995820X26001641"],"URL":"https:\/\/doi.org\/10.1016\/j.virs.2026.09.003","relation":{},"ISSN":["1995-820X"],"issn-type":[{"value":"1995-820X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A HiBiT-Tagged influenza A virus reporter system reveals cytokine-inhibitory micropeptide 53 as a modulator of viral infection and immunopathology","name":"articletitle","label":"Article Title"},{"value":"Virologica Sinica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.virs.2026.09.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.","name":"copyright","label":"Copyright"}]}}